LOCUS       NM_001081395            8951 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus angiomotin-like 1 (Amotl1), mRNA.
ACCESSION   NM_001081395 XM_976419
VERSION     NM_001081395.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8951)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8951)
  AUTHORS   Peralta,M., Ortiz Lopez,L., Jerabkova,K., Lucchesi,T., Vitre,B.,
            Han,D., Guillemot,L., Dingare,C., Sumara,I., Mercader,N.,
            Lecaudey,V., Delaval,B., Meilhac,S.M. and Vermot,J.
  TITLE     Intraflagellar Transport Complex B Proteins Regulate the Hippo
            Effector Yap1 during Cardiogenesis
  JOURNAL   Cell Rep 32 (3), 107932 (2020)
   PUBMED   32698004
REFERENCE   3  (bases 1 to 8951)
  AUTHORS   Phua,Y.L., Chen,K.H., Hemker,S.L., Marrone,A.K., Bodnar,A.J.,
            Liu,X., Clugston,A., Kostka,D., Butterworth,M.B. and Ho,J.
  TITLE     Loss of miR-17~92 results in dysregulation of Cftr in nephron
            progenitors
  JOURNAL   Am J Physiol Renal Physiol 316 (5), F993-F1005 (2019)
   PUBMED   30838872
REFERENCE   4  (bases 1 to 8951)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8951)
  AUTHORS   Liegel,R.P., Finnerty,E., Blizzard,L., DiStasio,A., Hufnagel,R.B.,
            Saal,H.M., Sund,K.L., Prows,C.A. and Stottmann,R.W.
  TITLE     Using human sequencing to guide craniofacial research
  JOURNAL   Genesis 57 (1), e23259 (2019)
   PUBMED   30375152
REFERENCE   6  (bases 1 to 8951)
  AUTHORS   Ernkvist,M., Luna Persson,N., Audebert,S., Lecine,P., Sinha,I.,
            Liu,M., Schlueter,M., Horowitz,A., Aase,K., Weide,T., Borg,J.P.,
            Majumdar,A. and Holmgren,L.
  TITLE     The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase
            activity in migrating endothelial cells
  JOURNAL   Blood 113 (1), 244-253 (2009)
   PUBMED   18824598
REFERENCE   7  (bases 1 to 8951)
  AUTHORS   Aase,K., Ernkvist,M., Ebarasi,L., Jakobsson,L., Majumdar,A., Yi,C.,
            Birot,O., Ming,Y., Kvanta,A., Edholm,D., Aspenstrom,P., Kissil,J.,
            Claesson-Welsh,L., Shimono,A. and Holmgren,L.
  TITLE     Angiomotin regulates endothelial cell migration during embryonic
            angiogenesis
  JOURNAL   Genes Dev 21 (16), 2055-2068 (2007)
   PUBMED   17699752
REFERENCE   8  (bases 1 to 8951)
  AUTHORS   Sugihara-Mizuno,Y., Adachi,M., Kobayashi,Y., Hamazaki,Y.,
            Nishimura,M., Imai,T., Furuse,M. and Tsukita,S.
  TITLE     Molecular characterization of angiomotin/JEAP family proteins:
            interaction with MUPP1/Patj and their endogenous properties
  JOURNAL   Genes Cells 12 (4), 473-486 (2007)
   PUBMED   17397395
  REMARK    GeneRIF: Data show that MUPP1 interacts with angiomotin (Amot),
            JEAP/Amot-like 1 and MASCOT/Amot-like 2, and that all the Amot/JEAP
            family proteins also interacted with Patj, a close relative of
            MUPP1.
REFERENCE   9  (bases 1 to 8951)
  AUTHORS   Bratt,A., Wilson,W.J., Troyanovsky,B., Aase,K., Kessler,R., Van
            Meir,E.G. and Holmgren,L.
  TITLE     Angiomotin belongs to a novel protein family with conserved
            coiled-coil and PDZ binding domains
  JOURNAL   Gene 298 (1), 69-77 (2002)
   PUBMED   12406577
  REMARK    Erratum:[Gene. 2003 May 22;310;231. Meir, EG [corrected to Van
            Meir, EG]]
REFERENCE   10 (bases 1 to 8951)
  AUTHORS   Nishimura,M., Kakizaki,M., Ono,Y., Morimoto,K., Takeuchi,M.,
            Inoue,Y., Imai,T. and Takai,Y.
  TITLE     JEAP, a novel component of tight junctions in exocrine cells
  JOURNAL   J Biol Chem 277 (7), 5583-5587 (2002)
   PUBMED   11733531
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CT030247.6 and
            CT485607.8.
            
            On Feb 6, 2007 this sequence version replaced XM_976419.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151000.1, SRR10223971.8892.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               CT030247.6         203508-203774
            268-417             CT485607.8         194650-194799       c
            418-1375            CT485607.8         190953-191910       c
            1376-1664           CT485607.8         173350-173638       c
            1665-1809           CT485607.8         170874-171018       c
            1810-1899           CT485607.8         169822-169911       c
            1900-2045           CT485607.8         160274-160419       c
            2046-2195           CT485607.8         156658-156807       c
            2196-2386           CT485607.8         153773-153963       c
            2387-2512           CT485607.8         149821-149946       c
            2513-2742           CT485607.8         148591-148820       c
            2743-3018           CT485607.8         146730-147005       c
            3019-8951           CT485607.8         140165-146097       c
FEATURES             Location/Qualifiers
     source          1..8951
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 4.12 cM"
     gene            1..8951
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /note="angiomotin-like 1"
                     /db_xref="GeneID:75723"
                     /db_xref="MGI:MGI:1922973"
     exon            1..267
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     CDS             219..3125
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /note="junction-enriched and -associated protein"
                     /codon_start=1
                     /product="angiomotin-like protein 1"
                     /protein_id="NP_001074864.1"
                     /db_xref="CCDS:CCDS40535.1"
                     /db_xref="GeneID:75723"
                     /db_xref="MGI:MGI:1922973"
                     /translation="MRRAKSRRGPCEPVLRAPPPICYSPSSPVQILEDPAYFYPDLQL
                     YSGRHEASTLTVEASGGLRGKSVEDPLSSFHSPNFLRTPEVEMRGSEDVASGRVLQRL
                     IQEQLRYGTPTENMNLLAIQHQATGSAGPAHATTNFSSTETLTQEDPQMVYQSARQEP
                     QGQEHQGDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQQQQQQQQ
                     QQQGQGPLSHTYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSER
                     IMQLSLERNGAKQHLPSSGNGKSFKAGGEPSPAQPVCKALDPRGPPPEYPFKTKPMKS
                     PVSKNQDHGLYYNDQHPGVLHEMVKPYPAPQPARTEVAVLRYQPPPEYGVTSRPCQLP
                     FPSTVQQHSPMSSQTSSIGGTLHSVSLPLPLPISLAASQPLPASPNQQLGPDAFAIVE
                     RAQQMVEILTEENRVLHQELQGCYDNADKLHKFEKELQSISEAYESLVKSTTKRESLD
                     KAMRTKLEGEIRRLHDFNRDLRDRLETANRQLSSREYDGHEDKAAESHYVSQNKEFLK
                     EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQ
                     QALTQLQSACEKRGQMERRLRTWLERELDALRTQQKHGTGPPVSLPECNAPALMELVR
                     EKEERILALEADMTKWEQKYLEESTIRHFAMSAAAAATAERDTTISNHSRNGSYGESS
                     LEAHIWPEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSAS
                     LRPARSVPSIAAATGTHSRQTSLTSSQLTEEKKEEKTTWKGSIGFLLGKEHQGQASAP
                     LLPTTPASALSLPASTTSASSTHAKTGSKDSSTQTDKSTELFWPSMASLPSRGRLSTA
                     PSNSPILKHPAAKGAVEKQENSPGHGKASEHRGRVSNLLHKPEFPDGEMMEVLI"
     exon            268..417
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            418..1375
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1664
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1809
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1899
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..2045
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..2195
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            2196..2386
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            2387..2512
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            2513..2742
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..3018
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     exon            3019..8951
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8930..8935
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /note="hexamer: AATAAA"
     polyA_site      8951
                     /gene="Amotl1"
                     /gene_synonym="2310010G08Rik; 2310067L22Rik;
                     4932416D09Rik; JEAP; mFLJ00155"
                     /note="major polyA site"
ORIGIN      
        1 accagcgacc ctcctgggta gcacgctggc gactgggagc gcggggcgcc cagggacccg
       61 gcagcggggt ggggtgggtg ggactggagg gggaacgggg catctctctg ctgcccgagt
      121 gcagaggcac ccttcgccgc gcctcccagc cgccatcccc ctgccgccat tcccctgccg
      181 ccgcgttgcc caagccagga tcgtcccatg atcgccccat gcggagggca aagtcgcgcc
      241 ggggaccttg cgagcctgtg cttagagctc ctcctcccat ctgctacagc cccagcagtc
      301 ctgtgcagat tctagaagac cccgcctact tctacccaga cttgcagctc tattctggga
      361 ggcatgaagc atctactttg acagtggagg caagtggagg cctaaggggg aaaagcgtag
      421 aggaccctct ctccagcttc cactccccga acttcctgag gacgcccgag gtggaaatga
      481 gaggttctga ggatgtagcc tctggaagag tgttacagcg gctgatccag gaacaactgc
      541 gctatggcac cccaactgag aacatgaacc tgctggccat tcagcaccag gccacaggga
      601 gtgcagggcc agcccacgcc accaccaact tttcttccac ggaaaccctc actcaagaag
      661 atccacaaat ggtctatcag tcggcccgcc aagaaccgca gggtcaagag catcagggag
      721 acaatacggt gatggagaag caggtccggt ccacacagcc tcagcagaac aacgaggagc
      781 tccccacgta tgaggaagcc aaggcccagt cccagttctt caggggacag cagcagcagc
      841 agcaacagca gcagcagcaa cagcagcagc aacagcagca gggacagggg ccccttagcc
      901 acacttatta catggccgga ggtaccagtc agaagtcccg cactgagggg aggcccacag
      961 tgaaccgggc caacagtgga caggcgcata aggatgaggc cctgaaagaa ctaaagcagg
     1021 gccatgtccg gtccctcagt gagaggatca tgcagctgtc actggagagg aatggggcta
     1081 agcaacacct ccccagctct ggaaatggaa agagcttcaa agctggagga gagccatccc
     1141 cagctcagcc tgtctgtaaa gcactggacc ctcgtggccc tccacctgaa taccccttca
     1201 agaccaagcc aatgaaatcc ccagtcagca agaaccaaga tcacggtctt tactacaatg
     1261 accagcaccc tggggtactc catgagatgg tcaaacctta cccagcacct cagcctgcga
     1321 gaacagaagt ggccgtcctg aggtatcagc cacccccgga gtatggcgtc accagccggc
     1381 cctgccagct gccttttcca tctacggtgc agcagcatag ccccatgtcc tctcagacct
     1441 cctccatcgg tggtactctg cactccgtct ccctgcctct tccacttccc ataagcctgg
     1501 cggcttcaca gcccctacca gcctccccca accagcagct tggaccggat gcctttgcga
     1561 ttgtggagcg agcccagcaa atggtagaga tcctgacaga ggagaaccgt gtgcttcacc
     1621 aggagcttca gggctgctat gacaacgctg acaagctcca caagtttgaa aaagagctgc
     1681 agagtatttc ggaggcctac gagagcctgg tcaagtccac caccaagcgt gagtctctgg
     1741 acaaggcaat gagaaccaag ctcgaaggcg agataaggag acttcatgac ttcaacagag
     1801 atctccgaga tcgactggag acagccaaca ggcagctgtc cagcagggaa tacgatgggc
     1861 atgaagacaa agctgcagag agccattacg tgtcccagaa caaagaattc ttgaaggaaa
     1921 aggaaaagtt ggaaatggag ttggcagcag tgcgtacggc aagtgaggac catcggaggc
     1981 acatcgagat cctggaccag gctttgagca atgcgcaggc tagagtgatc aaactggagg
     2041 aagagttacg agagaagcaa gcctatgtgg aaaaggtgga gaagctgcag caggccctga
     2101 cccagctgca gtcagcgtgc gagaagcgag ggcagatgga acgcaggttg cggacctggc
     2161 tggagaggga gctagacgct ctgaggacac agcagaaaca tggcacaggc cctccagtca
     2221 gtctcccaga atgtaatgct cctgccctca tggagctggt gagggagaag gaggagcgga
     2281 tcctcgcctt ggaggccgac atgaccaagt gggagcagaa gtacctggaa gagagcacca
     2341 tccggcactt tgccatgagc gcagctgccg ctgccacagc cgagagggac accaccatca
     2401 gcaaccactc gaggaatggc agctatgggg agagctccct ggaggcccac atctggccag
     2461 aggaagaaga agtggtgcag gccaacagga ggtgtcagga catggagtac actattaaaa
     2521 acctccatgc caaaatcata gagaaggatg ccatgataaa ggtcctgcag cagcgatccc
     2581 gtaaggatgc tgggaagacg gactctgcca gcctgaggcc tgcccgctct gtcccatcca
     2641 tcgctgcggc cactgggaca cattctcgcc agacttctct taccagcagc cagctgacag
     2701 aagagaaaaa ggaagagaag acgacctgga aagggagtat aggattcctg ctgggaaagg
     2761 aacaccaggg acaggcatct gcccctctgc tgccgaccac acctgcctct gcattgtccc
     2821 ttccggcctc taccacatcg gccagcagca cccacgccaa gacgggcagc aaggacagca
     2881 gcacacagac cgacaagagc acggagctct tctggcccag catggcttcc ctccccagcc
     2941 gtggcaggct gagcacagcc ccttccaaca gccccatcct aaagcatcca gctgccaaag
     3001 gagccgtgga gaagcaggag aactctcctg gtcatgggaa ggcatcggag cacagaggcc
     3061 gagtcagcaa cttgctgcac aagcctgagt tcccagatgg cgagatgatg gaagtgctca
     3121 tctagcgtcg tcctgtggcg cttgccagca tgctgacaga tgagaacaga ggctgaaaga
     3181 agagctccag atgggcagtt gcagtagcaa ctgcaaaacc aggacaggtg tggactcgtc
     3241 acaatgttac caaaacagct ggctcactat ctgcagaggg agtgagagag gacgcatgta
     3301 ggcttggaag cagagtagag aaggaggagg agtggaattt tccattgtag agaaattgta
     3361 tgtcttaggg aggctccatg cttccccatt cttggcttat aaacagatga agaagagctg
     3421 ggccttcctt ggaatcccct tgttcccttt gccttttagc aggtttggtt taagaagaat
     3481 ctgctagaaa tcctgaaagc ccatctcggc ataatggtgt gtgtgtgtgt gtgtgtgtgt
     3541 gtgtgtgtgt gtgtgtgtgt gtgtggtgtc cttagcaaat acatccagga taatggggaa
     3601 tttcaagttt tgtcaccttc ttggctgttt cgtttgtggt ttgtgatttc agagagtgtg
     3661 aagctttgct tgtttggatt ggatggtatt ttctaagcag gatgtgagca agatgccctt
     3721 gccctcaccc atcctgattt ctttgagctt atctgtctca tctctactta ctattttatt
     3781 gttgtatttt tcctgtttaa ttagacatag cagagttcct tatatatggg acttaggaga
     3841 ctaccatcct tgctgtggtg tccagatgga cagagcctcg tgttggcacc ccaactgctc
     3901 ttcccacctt tgcttagcag aactgcagct gtcagcctta ttgtgagcta gagatacctg
     3961 gctgaggagt ccatgagttg ctgacataac atcatgcctc tgatgtgcat ctctctcacg
     4021 tccacactct tgctaggagg ttgacaatta caccccatcg ccctgtgggg aagacttcct
     4081 tgtgaatagg tgccacagga acccatgatg gcttacccag agctctctag gtagcatggg
     4141 aggtctcagc aggcatcccc agcctttctt gtatttgaag ctctcaggtg gtcttttgtt
     4201 gctctcccct gccccattct gccctggttg ctgttgataa gcacagtgcc atccctgatc
     4261 aattcttttt ccctgtgaat ttgtttcata acccatcaga ctggtagaca cacagcacaa
     4321 tcagtatcac agaaagggac acgacttacc tgaagtgagg cagcaaagtc atggaaatga
     4381 gtccctatga acaagaggca ggacctgagg ctgctgccac aagctctcat gttcattgct
     4441 gtggaagctg gcttcctgga aaccccagaa gaagctgccc aggggagggt gaactatctc
     4501 cagatcagta aggtttattt ccaagtcccc ttcctcatca ctcctttttg gctcaagaga
     4561 aaaatgaaaa gtggtaattc tgtgacgtca agtccctctt aagtgcagca ctgaaaatag
     4621 cttggctcag agagctctgc ttggatcatg tgtcctagga ctcatctcta ggatgagact
     4681 gtggcctccc caggttgagg tggtacatgt attgtgagag acgtagcctg gagaacagag
     4741 aagaagagag gcaaggggag gagagagcag tggtgtttcc ctacaggacc ctggaccatc
     4801 tgacaagaca gaggaggtgg gactagacta cccacactcc acttggcagt gggaaccagg
     4861 ctgggagcct cccaccccct ccttaactct tctctcagat cttgcagcct gagtactgag
     4921 cttgccctgt gccttgtggg gaagggagtg agaaggcagc ataagaggtc ttgccagttg
     4981 agacagaagc aggtaggtgc aggaactatt ttggataggg catgttgttc agttgatggc
     5041 aactaattct cttaagaaca tattgtctcc tattaatgtt ggggacaaac ccagaaaggg
     5101 aagggtatag agatggggaa ttggtgagat cttccagccc tgagaccatg tctgagccac
     5161 cccaaactta ggctatctcc cagcatagga gtgagacact gcccagttta ctcaaattct
     5221 agtgtacgtg ttccagacac attgcacaca cagacagaaa gtctcctgtt ccagccccct
     5281 gcctccctgc gttgtcagtc tgtttcagtt gtctgaaaac aaaggggaca cagaccaggg
     5341 ctttaactgc aagtgaactg tggcttttgt tcaagagtcc gtgttgagag agatgggcta
     5401 tgggctttca gatagaggcc cttcagtctt ctgtccttgt aattctcttg aagggtgcat
     5461 gatagaggag ccccaggcac tcgggagcct cgctgtgctc tggggagttc atgggatcta
     5521 aactctttcg acaccaaaca acagtactac ataggtattt tggtacaaac tgaaagcact
     5581 agaaaaagtg cctgttgaat ggtcctcaaa gcaccagaga aacgaggcca ggttctccct
     5641 cctggttgtt cagatgcaga agctggaccc aggaggcata cagcccatct ccaagcttca
     5701 cttaaagcaa agactcagaa caagaggctc agtcacaggc tgcacggcct tgaacatgcg
     5761 cagcgctatg cctggtgctc tgtggcccaa tttgtgatac ttgtgtgcac acagggaagc
     5821 tgtcacacct ctcagggcct gaaaacagga ctaaacccaa gcctcatata actaaccaca
     5881 ccgccaccat ccacaggcgt ggatggaagt cttcatgttc tgttataagc acaactacaa
     5941 agcaaattaa aaaaataaat aaataaaagt ccttcctcat agtgcagaag gctcgttttc
     6001 agatctcttg gagcatttga tcatagaact tgagggtctt ctcttgggat aaagaaagga
     6061 taaataaagg ctgtggcact tagtggtggt tggccagcat cctgctttgt ccttgagtga
     6121 gcagtgtggt gatgtctgaa tacttccagg tgtcgtgtgg aacctgagaa gtattgagat
     6181 catgtctctg tccctgtggt ttcagtaagt agattcttct atgtgtaagc actatttctc
     6241 tctggaggtt catagcacta agctgccaag aaaaacacgt tcatttgcaa agaattaaga
     6301 gtgtgtgcta aacacttgac attgttcttt gtttctcaga agctagtgac cagcaacgtg
     6361 gagtgttcag caagtcccca ccatgcctgc agggtggggc tgctcccttc cacacccagc
     6421 tttccttagg ggtggagaca gggaatggtg ggacctgtgt tgttccgtcc cgcagaggtc
     6481 tctctttgga gcccatgtat aaggcttgac atttttctgt gagtagattt agaggcagtt
     6541 gttccaagtg aattctggcc tcagtacaaa gaatccagtg gttctgacac tcgggacaaa
     6601 agctctggta tcccctgtag agaggctctg tcctgctttg ctccagccac tcacacatag
     6661 ttaataaagt ggctgaagct cctcccttcc cagagctgct gtgctgggga cgctgtctgc
     6721 agcccgcccg agtcccagag attggtgtga gcagtcagat aaggctgatc tgggagacgg
     6781 aggaggtggc catgacacaa ggtgttgtca ggagaagatg attgtgacac aaggtgttgt
     6841 caggaggaga tgactgtgac acaaggtgtc ttcaagcagc tcctttgtga gtaggctgca
     6901 gagagccatc ctgagtggga ggttgtgttg tttaaacaca tggtgtcttc tttgtctgca
     6961 ctggatggag cagggtttgt ttctatgtgt tctccaggtg agctcacacc ctctttaaga
     7021 aaaggggtct tgtggatgtt ggaagcaagg tctgtcaaac attcttaaat ggtgatgcta
     7081 gagaaaagcg agccccctgt aacttcccta aaagccgact cagccactaa gtatacatgt
     7141 tgactttctt ctactttttt tctagttaat cagtgtgatt taaatgtctt tagctgatgt
     7201 gaggactttt taaaaggcag tagtttgtgg tgcagctccg tggaacaggt tgtgtaataa
     7261 gaaacctcag aagccaggct tcaagggggc cgggtgtgtg tgtgtgtgcg gggtgcaccc
     7321 aggccagcct ttcagtggat tcctattctc atttagtaat tgaatggtat attacattat
     7381 atgtaagtgc atacatataa ggtggaattt ttctcaatat aaaaaaagaa agaaagaaag
     7441 aaagaaagaa agaaagaaag aaagagaaaa agaaagaaag aaatgtaaga aagagaaaga
     7501 aatccttttg ttttcctgtg agctcgctcc ttggggagga ctacagggct ccccatgtaa
     7561 aatggctgtt gactcctcta gcacaatggc ctccaaggtc tggcctgctc ctcggattcc
     7621 ctttgaagtg agaggtcatt gtcttttgag aatggattta agttttgaaa atagcccaca
     7681 ttgttccagc acaagggaac gaacataggg caactagtca gaatcagaac cccagggcca
     7741 tcagatgact tggtgaaaag gcacttccac caaagccaag acctgagttt gatccccagg
     7801 aaccccatag taggagagag ccaactgcag caagttgtcc tctgactcag acacacacac
     7861 acacacacac acacacacac acacacacgc gcgcgcacgc gcgcgcacat acatacacat
     7921 gcacacacac acttacatgc acacacatga acatgcacat gcacacacac acatgcatac
     7981 atacatacac atgcacacac acatatatgc acacacatga acatgcacac acacatacat
     8041 gcacacacac atacatgcac acacatgcac acgcacacac tcgtgcgcac acacagtttt
     8101 tagaagacta cctaatgtgt aggaaaaggg ttattagtac ctgcaacctc tagggcctcg
     8161 ttttcaagcc cgcttctctc tccaggcttc atatgtgtgc aacccctgca tacactacag
     8221 acctaagtac atataaatat gaacagccaa taggtactct gtaaaatgga tattcttaag
     8281 tgcatgttat tgttgtgtgt gccgtgactg aggtgtgtgt tcgtcatgag actttgcttc
     8341 ttagctgaat taagactctg ccctccctcc gaggcaggaa ataggctgca gcttctggaa
     8401 tcagcttctc acgttttccc gcctttgttg tgtttactcg tggctttgtc tgagagtctg
     8461 ttctcacata cacacctgta agtatttatt acaaggtaga atggggacag gcagccacag
     8521 tacttgtatt tgaatgtttc cagggaggga caatggagcc ccctcctcag tgaggtgctc
     8581 acagaatctg tgtcaaattc tgtgaaccag ggccaacact ggtaccagct tcaccctgac
     8641 ctggggccac tgccctctct ctccactgcc ttgtgtgtgt ataggtgtgg ttgtgtgtgt
     8701 gtgtctctgc tgggggcatg tgccgcactt cccagcggac tctggtatcc atgtgtaacc
     8761 tttggcacct gtgttactgg actgcattga caggtggtgt acagatctgt acagatgggt
     8821 ctgtgtgaag agttggggag tcccccccac agtgaatatg gatactgttg gtcagccaaa
     8881 gattttccta ttctttgctg cttaaacttt gtgccttaat attgtaaata ataaatgttt
     8941 aaaacagcaa a
//
