LOCUS       NM_175179               8476 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus APC membrane recruitment 1 (Amer1), mRNA.
ACCESSION   NM_175179
VERSION     NM_175179.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8476)
  AUTHORS   Comai,G., Boutet,A., Tanneberger,K., Massa,F., Rocha,A.S.,
            Charlet,A., Panzolini,C., Jian Motamedi,F., Brommage,R., Hans,W.,
            Funck-Brentano,T., Hrabe de Angelis,M., Hartmann,C.,
            Cohen-Solal,M., Behrens,J. and Schedl,A.
  TITLE     Genetic and Molecular Insights Into Genotype-Phenotype
            Relationships in Osteopathia Striata With Cranial Sclerosis (OSCS)
            Through the Analysis of Novel Mouse Wtx Mutant Alleles
  JOURNAL   J Bone Miner Res 33 (5), 875-887 (2018)
   PUBMED   29329488
  REMARK    GeneRIF: analysis provides a novel model for WTX-caused bone
            diseases and explains on the molecular level how truncation
            mutations in this gene may retain some of WTX-protein functions.
REFERENCE   2  (bases 1 to 8476)
  AUTHORS   Kim,W.J., Wittner,B.S., Amzallag,A., Brannigan,B.W., Ting,D.T.,
            Ramaswamy,S., Maheswaran,S. and Haber,D.A.
  TITLE     The WTX Tumor Suppressor Interacts with the Transcriptional
            Corepressor TRIM28
  JOURNAL   J Biol Chem 290 (23), 14381-14390 (2015)
   PUBMED   25882849
  REMARK    GeneRIF: WTX stabilized chromatin binding by TRIM28 and contributed
            to transcriptional repression of repetitive sequences by TRIM28 in
            mouse embryonic stem cells.
REFERENCE   3  (bases 1 to 8476)
  AUTHORS   Moisan,A., Rivera,M.N., Lotinun,S., Akhavanfard,S., Coffman,E.J.,
            Cook,E.B., Stoykova,S., Mukherjee,S., Schoonmaker,J.A., Burger,A.,
            Kim,W.J., Kronenberg,H.M., Baron,R., Haber,D.A. and Bardeesy,N.
  TITLE     The WTX tumor suppressor regulates mesenchymal progenitor cell fate
            specification
  JOURNAL   Dev Cell 20 (5), 583-596 (2011)
   PUBMED   21571217
  REMARK    GeneRIF: The constellation of anomalies in Wtx null mice suggests
            that this tumor suppressor broadly regulates mesenchymal progenitor
            cells in multiple tissues.
            Erratum:[Dev Cell. 2012 May 15;22(5):1109-17]
REFERENCE   4  (bases 1 to 8476)
  AUTHORS   Comai,G., Boutet,A., Neirijnck,Y. and Schedl,A.
  TITLE     Expression patterns of the Wtx/Amer gene family during mouse
            embryonic development
  JOURNAL   Dev Dyn 239 (6), 1867-1878 (2010)
   PUBMED   20503382
REFERENCE   5  (bases 1 to 8476)
  AUTHORS   Jenkins,Z.A., van Kogelenberg,M., Morgan,T., Jeffs,A., Fukuzawa,R.,
            Pearl,E., Thaller,C., Hing,A.V., Porteous,M.E., Garcia-Minaur,S.,
            Bohring,A., Lacombe,D., Stewart,F., Fiskerstrand,T., Bindoff,L.,
            Berland,S., Ades,L.C., Tchan,M., David,A., Wilson,L.C.,
            Hennekam,R.C., Donnai,D., Mansour,S., Cormier-Daire,V. and
            Robertson,S.P.
  TITLE     Germline mutations in WTX cause a sclerosing skeletal dysplasia but
            do not predispose to tumorigenesis
  JOURNAL   Nat Genet 41 (1), 95-100 (2009)
   PUBMED   19079258
  REMARK    GeneRIF: The observed phenotypic discordance dependent upon whether
            a mutation is germline or occurs somatically suggests the existence
            of temporal or spatial constraints on the action of WTX during
            tumorigenesis.
REFERENCE   6  (bases 1 to 8476)
  AUTHORS   Rivera,M.N., Kim,W.J., Wells,J., Driscoll,D.R., Brannigan,B.W.,
            Han,M., Kim,J.C., Feinberg,A.P., Gerald,W.L., Vargas,S.O., Chin,L.,
            Iafrate,A.J., Bell,D.W. and Haber,D.A.
  TITLE     An X chromosome gene, WTX, is commonly inactivated in Wilms tumor
  JOURNAL   Science 315 (5812), 642-645 (2007)
   PUBMED   17204608
REFERENCE   7  (bases 1 to 8476)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK392507.1, AL671765.6 and CD645252.1.
            
            On Oct 30, 2007 this sequence version replaced NM_175179.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK392507.1, AK049774.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-433               CK392507.1         1-433
            434-8404            AL671765.6         39842-47812         c
            8405-8476           CD645252.1         278-349
FEATURES             Location/Qualifiers
     source          1..8476
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 41.99 cM"
     gene            1..8476
                     /gene="Amer1"
                     /gene_synonym="2810002O09Rik; Fam123b; Wtx"
                     /note="APC membrane recruitment 1"
                     /db_xref="GeneID:72345"
                     /db_xref="MGI:MGI:1919595"
     exon            1..183
                     /gene="Amer1"
                     /gene_synonym="2810002O09Rik; Fam123b; Wtx"
                     /inference="alignment:Splign:2.1.0"
     exon            184..8469
                     /gene="Amer1"
                     /gene_synonym="2810002O09Rik; Fam123b; Wtx"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..3670
                     /gene="Amer1"
                     /gene_synonym="2810002O09Rik; Fam123b; Wtx"
                     /note="protein Fam123b; family with sequence similarity
                     123, member B"
                     /codon_start=1
                     /product="APC membrane recruitment protein 1"
                     /protein_id="NP_780388.2"
                     /db_xref="CCDS:CCDS41067.1"
                     /db_xref="GeneID:72345"
                     /db_xref="MGI:MGI:1919595"
                     /translation="MESQQDEAVQTKGASTSSDAQDQGAEKGAKNKTTEATEGPTSEP
                     PLSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKVSSKKSLNKSKTHDGLSEA
                     SQGPEDVVIEETDLSTPLSKSSAQFPSSQSANGALEIGSKHKTSGTEAIEKAGVEKVP
                     SVHKPKKSLKSFFSSIRRHRKGKTSGADQSVPGAKELEGARTRSHEHVSSISLPSSEE
                     IFRDTRKENAKPQDAPGPKMSPAQVHFSPTTEKAACKNPEKLTRTCASEFMQPKPVLE
                     GGSLEEPHTSETEGKVVAGEVNPPNGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQ
                     DMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDNDDEEEEEEEEEEE
                     EEEEEEEEEEEEEEEEELLEDEEEVKDGEENDDLEYLWASAQIYPRFNMNLGYHTAIS
                     PSHQGYMLLDPVQSYPNLGLGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALG
                     LAHRDCLPRDSYSGDALYEFYEPDDSLEHSPPGDDCLYDLRGRNSEMLDPFLNLEPFS
                     SRPPGAMETEEERLVTIQKQLLYWELRREQREAQEACAREAHAREAYARDTHTRESYG
                     RNVRARETQALEAHSQEGRVQETKVRQEKPALEYQMRPLGPSVMGLVAGTSGGSQTSH
                     RGTTSAFPATSSSEPDWRDFRPLEKRFEGTCSKKDQSTCLMQLFQSDAMFEPDMQEAN
                     FGGSPRKAYPSYSPPEEPEEEEEEKEGNATVSFSQALVEFTSNGNLFTSMSYSSDSDS
                     SFTQNLPELPPMVTFDIADVERDGEGKCEENPEFNNDEDLTASLEAFELGYYHKHAFN
                     SYHSRFYQGLPWGVSSLPRYLGLPGVHPRPPPAAMALNRRSRSLDNAESLELELSSSH
                     LAQGYMESDELQAHQEDSDEEGEEEEGEWGRDSPLSLYTEPPGVYDWPPWAHCPLPVG
                     PGLAWMSPNQLYEPFNQSSYVQATCCVPPVAMPVSVPGRTPGDSVSQLARPSHLPLPM
                     GPCYNLQSQASQSGRAKPRDVLLPVDEPSCSSISGANSQSQAKPVGITHGIPQLPRVR
                     PEPFQLQPNHYRASNLDLSKERGEQGASLSTSYSSTAMNGNLAK"
     regulatory      8430..8435
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Amer1"
                     /gene_synonym="2810002O09Rik; Fam123b; Wtx"
                     /note="hexamer: AATAAA"
     polyA_site      8464
                     /gene="Amer1"
                     /gene_synonym="2810002O09Rik; Fam123b; Wtx"
                     /note="major polyA site"
ORIGIN      
        1 ccggggtgaa gggggtatgg gggagctgcc cagagcctgg agaagggtag tcggcgcaga
       61 agactgctgt agtcccggtg aaggctgcgg caggagcagt ggtggcgttc tcagcagagg
      121 ctccagctca aatcggagca gcgcagcaga caataaacag cgctgggagc tggacctggc
      181 aggaccccac tgtgatgctt cctgactgat catgttataa gtgtgcccgg aatccaaagg
      241 cagcatatcc agtggaagaa ttgtcttcat catggagagt caacaggatg aagctgttca
      301 aaccaaagga gcatcaactt ctagcgatgc ccaagaccag ggagctgaaa agggagccaa
      361 gaataagaca actgaggcaa cagaaggacc aacatcagag cctcccttat caggcccagg
      421 taggctgaag aaaactgcca tgaaactctt tggtggcaag aagggaatct gtactctgcc
      481 tagtttcttt gggggtggac gaagcaaagg ttctgggaaa gtcagctcta agaaaagtct
      541 aaacaagagt aagactcacg atggtctaag tgaagcgtct cagggacctg aagatgttgt
      601 cattgaagaa acagacctct ctacaccttt gtccaagtca tctgctcaat ttcctagctc
      661 ccagagtgcc aatggagcgt tggagatagg ctctaaacat aagacatctg ggactgaagc
      721 catagaaaaa gctggagttg agaaggtacc ctctgtgcac aagccgaaga aaagcctaaa
      781 aagcttcttt agcagtatcc gccgtcaccg gaagggcaag acttctgggg ctgaccaaag
      841 tgtgccaggg gccaaggaac ttgagggggc aagaaccagg tctcatgagc atgtgagttc
      901 aatctctctg cccagctctg aggagatatt ccgagacact agaaaggaaa atgccaaacc
      961 ccaggatgcc cctggaccaa aaatgtctcc agcacaagta catttttcac caactactga
     1021 gaaggcagct tgtaaaaatc cagaaaaact cacaaggacc tgtgcctcag agttcatgca
     1081 gcccaagcct gttcttgaag gtggtagtct agaggagccc cacacttcag aaacagaagg
     1141 aaaagtggtg gcaggagaag taaacccacc caatggccct gttggggatc agctaagcct
     1201 cttgtttggg gatgttacat cgctaaaaag ctttgactca ctgacaggtt gtggtgacat
     1261 tatagcagaa caggacatgg acagcatgac agatagcatg gcctctggtg gccagagggc
     1321 caaccgagat gggaccaagc gaagttcctg cttggtaacc taccaaggag gtggggagga
     1381 gatggccttg ccagatgatg atgacaatga tgatgaagaa gaagaagaag aagaagaaga
     1441 agaagaagaa gaagaagaag aagaagaaga agaagaagaa gaagaagaag aagaagaatt
     1501 attagaggat gaagaggagg ttaaggatgg agaggaaaat gatgacttag agtatctgtg
     1561 ggcaagtgcc cagatatacc caagatttaa tatgaatctg ggctaccata ctgctatatc
     1621 tcccagccac cagggctaca tgcttcttga cccagttcag tcttatccta atctaggcct
     1681 tggagaactt ttgacacctc agagcgacca gcaagagtct gctcccaata gtgatgaagg
     1741 ttattatgac tctaccacac caggatttga ggatgattca ggtgaggctc tgggacttgc
     1801 ccacagggat tgtctaccca gggacagcta tagtggtgat gcgctatatg agttctatga
     1861 gccagatgac agtcttgagc actccccacc tggggatgac tgcctatatg acctccgtgg
     1921 acgcaactca gagatgttgg atcctttctt gaacttggag cccttttctt ctcggccacc
     1981 tggggcaatg gaaaccgagg aagaacggct agtgaccatc cagaagcagt tgctatactg
     2041 ggaacttcgc cgggagcagc gtgaggctca agaggcatgt gccagagagg ctcatgccag
     2101 agaagcttat gcccgagaca cccatactcg ggaatcttat ggcagaaatg tccgagcccg
     2161 agaaactcag gccttagagg ctcattctca agagggtcga gtccaagaga ccaaggtacg
     2221 gcaggagaag cctgccttgg agtatcagat gaggccctta ggtccctcag tgatgggtct
     2281 ggtggcaggg acatcaggag gttctcagac ttctcaccgg ggaaccactt cagctttccc
     2341 tgctacttct agcagtgagc cagactggag ggatttccgt cctctggaga agcgttttga
     2401 ggggacttgt tccaaaaaag atcaaagtac ttgtttaatg cagctcttcc agagtgatgc
     2461 catgtttgag ccagacatgc aagaagcaaa ttttggaggc tcacccagga aggcgtaccc
     2521 tagttactca ccccctgagg agccagagga agaagaagag gagaaggaag ggaatgccac
     2581 tgtgagtttc tcacaggccc tagtagagtt caccagcaat ggaaaccttt ttaccagcat
     2641 gtcctacagc tctgattctg actcatcctt cactcaaaac ctccctgagc tgccccccat
     2701 ggtcaccttt gatattgctg acgtggaacg agatggagaa ggcaagtgtg aagagaatcc
     2761 tgagttcaac aatgacgaag atcttacagc ctccttggaa gcttttgagc tgggttatta
     2821 ccacaaacat gccttcaaca gctatcacag tcggttctac caaggcctgc cctggggagt
     2881 tagcagcctc cctcgatact taggactccc cggagtccac cctcgacctc ctcctgctgc
     2941 aatggcactc aataggagaa gccgttccct tgacaatgca gagtctctgg agctggagct
     3001 ctccagttct cacctagccc agggttacat ggagtctgat gagctccagg cccaccagga
     3061 agattcagat gaagaaggtg aagaagagga aggagaatgg ggtcgggata gtcccttgtc
     3121 tctctacact gaacctccag gggtctatga ctggcctccc tgggctcact gtcctcttcc
     3181 agtggggcca ggtcttgctt ggatgagccc taatcagttg tatgagcctt tcaatcagtc
     3241 ttcctatgtg caggcaacct gttgtgtacc tcctgtggca atgccagtgt cagtgccagg
     3301 aagaacacct ggagactctg tgtctcagct agctcgacct tcgcacctac ccctgcccat
     3361 gggcccttgc tataaccttc aatcacaggc ctcccagagt gggagggcca agcctcggga
     3421 tgtactgctg cctgtagatg agcccagttg ctcttccatt tctggagcca actctcagtc
     3481 tcaagccaag cctgtaggta tcacccatgg tatccctcag ctgcccaggg tgcggcctga
     3541 acccttccag cttcaaccca atcactatcg agcttccaac cttgacctgt caaaggagag
     3601 gggtgagcaa ggtgcctctc tctctaccag ctactcctct actgccatga atggaaacct
     3661 agccaagtag ttatcaattc cagaatggag acctgagcat gtgaattggg ggtcaagggt
     3721 tgggcagagg ggtaggggtg agtagtgctg ttccacttga aaatcttatt ggctaagata
     3781 aactcctctg agttttcact ttgcccacct tcctctgcca tctttggcca ggttcagctc
     3841 aattatatct gcctagggag gctgctgctt ctgtgctcca atttttgctt tggagtttct
     3901 tgtgacctat acagggcttg ggatgcatcc ttattgcagg ctgaacccct cttctctggt
     3961 cccttgctga ctaatgaacc actgatgagc agccaatttt ttgcactgac tctcacccag
     4021 agatgggagg cttgctagct attagcaata taaagttatg gtacatagcc ttcctaaccc
     4081 cattcctttc tagcacatca aatgactata acctatttat cccagttagt tatgtttaga
     4141 gtgggtcaag tagcatgtgt ctcgctccct gttgctgtgg actttggtat cacaactaga
     4201 tgatgtcctt ttaacctggc ctgccatagt ctagattgaa gacaaaaaca ctaatcctca
     4261 taagggggtg attaaatctg tccatattca agcagaatac aaagatagat agcttatgga
     4321 aaatgctgtg aggtcttgag ctgtggaata ataatatatc tatcttgttt gtttcctaag
     4381 cctgtggctg ttgcaggcat tttagaactt cccccttttc ctgtccctga aaaatttcat
     4441 ctcatcacaa tgaatgtagt atcttaactg agttaaagga agagaagcca cctaaattgg
     4501 gcttgactat atagagcatt gggtgttgtg agatgcaaaa gaggaaaaca gacagggtga
     4561 tccatttatc taaacaccaa gaagggatct cagactttgg aacttgaagc aactcagatt
     4621 aggagggaaa acttttccca tcctttctcc caaaccaaaa gtaaataaat aaataaaccc
     4681 ttggccgccc ctttgtaaag tggttccaag cttgtctaag acaggatgcc aaaggcatct
     4741 cacctgttgt aggcacacta aaaagctttt atcttccagt tagccaagtt cttagcattt
     4801 tcaaaggacc aggcttcttg agaggaaaga ttgtaatgta cccttgctct gccaaactac
     4861 agggctgatt tgcatggcag ttgcagtcct ttctgaaatg aacagcaccc tctcttctct
     4921 tgcatccatg caggtttctt tttctttttt ctatattttt tttctggaca aggtcccaca
     4981 ctgtagttct ctctagcctg gaacttacca tgtagaccac gatggcttct aactaacaga
     5041 gatccacctg cctctgcctc caagcaagcc cagcctaaat gttggaaaca ctagggaaga
     5101 gcttggtgtc aggaaaacat tgcaacaggc tcatcttgac caggttcaac atttccttaa
     5161 tcatctatat gaaacagttt ctttaaaatt ctccatcagg cccggtgtgg aggtatgtgc
     5221 cttttatctc aacactcaga aggaagaggc aattggagtt atatgagtgt gagaccagcc
     5281 tgttctacat agtgagttct aggccactag ggctacatag caagatagac cttgttttaa
     5341 atttttttct gtattggaat atgaaatatt ttggggatcg atatgttgat caaagttaga
     5401 actttttaaa tcttctgccc atgtccctct tctcacctca aagccatctt cacatctact
     5461 aagtgaagat atcaataggg ctcttgctca aaataaggca atttaccttg agaacagatg
     5521 ctggtggcct tctgagtcaa gattgctttg tagacatact ttctttgcca gggcatatat
     5581 tcataatatt tttcacagtt tctaagcttg ggattggccc tgtgcctttc ccccaaaaga
     5641 gcagatttga ttggtaaaat ctaacccctt gtaagtaact tcataacttt gcatggcacc
     5701 agcactagaa ccacccctca aggacctcag atcagctctc ttggatgact ttggctacat
     5761 cacgaagaag tgcatctctt gtggatctgg ataatgaaag tgaaaaaggc cttccttacc
     5821 ccaaccacat cgtcataaga gacacatgcc cagattttaa ccacttggcc tcctaccaaa
     5881 gctgttctgg gaaggtgagg ctgaacttag cctggttggg tggcaggaag taagcactca
     5941 atgcctttac aacaggaaaa gccacacctc ttgcctagtc aaggtagctt gagttgctgt
     6001 ttacatgtcg ctgccatcta cagcaggcac tagagctgtc cacagcctcc atagcccact
     6061 ggagaagggc taccagcctg tttggaagag gaagaaggaa tctaccctca cagttcagga
     6121 ggacagcaca gtgcaatatc tctgaaggga cctgctataa cttggatata ttttgctatg
     6181 ctttgaaact tcatacctta gagtaggacc tgaggcaaag tagaagtttg tggattgggt
     6241 aacatcattg ccttccaagt cctttcactg atctggctgc tagcctaggg acaaaatatt
     6301 tacaacctaa aatgggatag ccaagatgtc tacagaagca gactcctttt gagtatctaa
     6361 agcaaatact aactgcagcc tagaagggga aagaagattt ggctgcggat atatggtaat
     6421 ggcaacatga ttaccaatgg gatatgtaac caatctctag gtatctgtcc aaacatggac
     6481 aagtacttcc tttgctggca ccaaatatgc tacaaactac cagaagtgct gctattgtgt
     6541 tcaccctaag gctgtggcca gatgaacctc ctgactccat tgcaggtcct tggacaatgc
     6601 atttggatgt gactttaagg gaagatgtgc tgacagaagg aggctagctt tatgttgtta
     6661 cccagtacta ctatatagtg tcagctctga tcctgagaat ttcttagtaa cccagtccat
     6721 agaggaccag tgactgtggg tatggaaagc cacctagcag gcctcttcca aagccaggat
     6781 gccaatttct tggtgcttta gattctccaa ggaagctctg ccttggggat catctggctt
     6841 tagcttagat accagaccac aagcctcgtg gataatggtt tcagtaaatg ccagtgtccc
     6901 tcctcttagt gctatttcaa ggagggaagt agctttccac actcagaatg ttgggtgcat
     6961 gatttcatcc tgccaccagt ggctttttca cctgcaccag tgccaccact gccttcagcc
     7021 cttaggctca cttgctagag ggaggcatgg gggtttacca gggatacttc aagtttaccc
     7081 atgtgtatgt tgcatccaag ttgtttttaa tatatatata taaatatata tatcaaaagc
     7141 taattatcta tttttatatt gtttgcattt tatattcatg gaaacaatgt ttatcaattg
     7201 ttcttttctg atatatttta tttttaagcg gtgctgttta cagttttaaa caaaaaaaaa
     7261 agatgacaca aaaaatgctg ctgctcgtgc agagggatgt catctcaaag tgtctaggac
     7321 cctccctctt ttccctctcc cacctggctg tgtcacacta ttcattctct ttccacacgg
     7381 taaggacaga agatgcccat gtaccgaaga ccaataccag gtaacgcaag catgtggacc
     7441 ctggcagaca gcatgttttc tagctttcat tttatttacc ttttgagccc ttccttctct
     7501 tgtgtagacg ttttgaaagt actcctgcct cttgactttt attcttttcc tttctttata
     7561 ttttgtgctt gttttttgca aagtatcatg cccatattgt gtggtttgtt gtattaagtt
     7621 tctccaatgg agcattaggg gctcattcaa caccaggaga ctcgggatga cagatgacaa
     7681 tgctatttca acctccagga attggtcatc tccttgggag acacccttga atgagacttg
     7741 ccagcaattt agaagatggc aacattgtcc agaaaaggca ttaggtgatt ccttggtccc
     7801 tcttgctact ttgggagaat ctctccacat cctgcctcct ccttcccttc cctgttccag
     7861 ctcacaagtg gatggtactt ttggaaactg aactcttgtt gttttgtttt tttattgtaa
     7921 gtcttagccc ttaatggctg agttgtctct ttaaccagga tggcactttt aggaatggtg
     7981 actgttacag tcatggctgg gtggcctgat ccacggtttc tccatcctgt agtcattcca
     8041 aagaagaaaa tccacatggc atgtacattt gtgagggttg ggtctattaa gagggggctt
     8101 taattattcc tgttactatt ggtgcttatt ttccccgctg tatatggggg tggggaaggg
     8161 ctggggtaaa ccagaaatgt atatttaggt cacgttaaat aaaatggctg ggggaagaag
     8221 aaagatatga gtctaggtgt aagagttctc tcttccagga cagaaagggg attgtagctt
     8281 gttgctgcac ctgagcttcc cttccgcatt cctgagacat catggaatca tctgcatttg
     8341 ttacctctcc atccctagca ctcactggca tctggatatc ctgatacact gcctgtatgt
     8401 tacaacatat atttcatttg ctgaatgcta ataaacttct gtgctcatga gggacctcca
     8461 gtcactaaaa aaaaaa
//
