LOCUS       NM_172935               1463 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus amidohydrolase domain containing 2 (Amdhd2), mRNA.
ACCESSION   NM_172935
VERSION     NM_172935.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1463)
  AUTHORS   Kroef,V., Ruegenberg,S., Horn,M., Allmeroth,K., Ebert,L.,
            Bozkus,S., Miethe,S., Elling,U., Schermer,B., Baumann,U. and
            Denzel,M.S.
  TITLE     GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine
            pathway
  JOURNAL   Elife 11, e69223 (2022)
   PUBMED   35229715
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1463)
  AUTHORS   Bergfeld,A.K., Pearce,O.M., Diaz,S.L., Pham,T. and Varki,A.
  TITLE     Metabolism of vertebrate amino sugars with N-glycolyl groups:
            elucidating the intracellular fate of the non-human sialic acid
            N-glycolylneuraminic acid
  JOURNAL   J Biol Chem 287 (34), 28865-28881 (2012)
   PUBMED   22692205
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CT010502.14.
            
            On May 2, 2007 this sequence version replaced NM_172935.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK168432.1, AK154209.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               CT010502.14        25812-25963
            153-289             CT010502.14        26213-26349
            290-429             CT010502.14        26430-26569
            430-484             CT010502.14        30851-30905
            485-697             CT010502.14        31023-31235
            698-786             CT010502.14        31313-31401
            787-931             CT010502.14        31483-31627
            932-1039            CT010502.14        31698-31805
            1040-1108           CT010502.14        31949-32017
            1109-1210           CT010502.14        32873-32974
            1211-1463           CT010502.14        33460-33712
FEATURES             Location/Qualifiers
     source          1..1463
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.28 cM"
     gene            1..1463
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /note="amidohydrolase domain containing 2"
                     /db_xref="GeneID:245847"
                     /db_xref="MGI:MGI:2443978"
     exon            1..152
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..1299
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /EC_number="3.5.1.25"
                     /note="putative N-acetylglucosamine-6-phosphate
                     deacetylase; amidohydrolase domain-containing protein 2;
                     glcNAc 6-P deacetylase"
                     /codon_start=1
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="NP_766523.2"
                     /db_xref="CCDS:CCDS28475.1"
                     /db_xref="GeneID:245847"
                     /db_xref="MGI:MGI:2443978"
                     /translation="MRSGQCAAGAPVLQFTNCRILRGGTLLREDLWVRGGRILDPEKL
                     FFEERRVADEQRDCGGRILAPGFIDVQINGGFGVDFSKATEDVGSGVALVARRLLSHG
                     VTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYL
                     RSFEANAFHDVLATYGPLDNVCIVTLAPELDRSHEVIQALTAQGIRVSLGHSVADLRA
                     AEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTNPA
                     ALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLGGSIAP
                     MDVCVRHFLQATGCSVESALEAASLHPAQMLGLEKTKGSLDFGADADFVVLDDTLHVQ
                     ATYISGELVWQAEEAGP"
     exon            153..289
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            290..429
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            430..484
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            485..697
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            698..786
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            787..931
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1039
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1108
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1210
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1463
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1443..1448
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /note="hexamer: AATACA"
     polyA_site      1463
                     /gene="Amdhd2"
                     /gene_synonym="5730457F11Rik"
                     /note="major polyA site"
ORIGIN      
        1 ttccgattac ggctgctccg ggctctgccg gcttgcgccc aaagcttgct gggttcggcg
       61 cgactcacga tgcgtagcgg gcagtgcgca gcgggggccc cggtgctcca gttcaccaac
      121 tgccgcatcc tgcgtggcgg cacgctcctc agggaggatc tgtgggtgcg cgggggccga
      181 atcctggacc cagaaaagct gttttttgag gagaggcgtg tggctgatga gcagcgggac
      241 tgcggaggcc gcatcctggc gcctggcttt atcgatgtgc agatcaacgg tggatttggt
      301 gttgacttct ccaaggctac ggaggacgtg ggttcggggg tcgccctagt ggcccggagg
      361 ctcctgtccc acggtgtcac ctccttctgt cccaccctgg tcacctcccc accagaggtt
      421 tatcacaagg tccttcctca gatccctgtg aagagtggag gtccccatgg ggcaggggtc
      481 ctcggggtgc acttggaggg cccattcatc agccgggaaa agcggggtgc acaccccgag
      541 gcctacctcc gctcctttga agccaatgct tttcatgatg tgttggccac atatgggccc
      601 ctggacaacg tctgcattgt gacacttgcc cctgaactag accggagcca tgaagtgatc
      661 caggcactga cagcccaagg catccgtgtg tctctagggc actcagtggc cgacctgcgg
      721 gctgcagaag tggcagtgca gagtggggcc accttcatca ctcacctctt caatgccatg
      781 ttgcctttcc accaccgtga cccaggcata gtagggcttc tgaccagtga ccagctgccc
      841 ccaggccact gcatcttcta tgggatgatt gctgatggca tacacaccaa ccctgcagct
      901 ctgcgcattg ctcaccgggc ccatccccag gggctggtgc tggtcactga tgctgtccct
      961 gccctgggct tgggcaatgg ccgccataca ctgggacagc aggaggtgga ggtagatggg
     1021 ctaatagcgt acattgcagg caccaagaca ctgggtggca gcatagcccc catggatgtg
     1081 tgcgtccggc atttcctgca ggctacaggc tgtagtgtgg agtcggccct ggaagctgcc
     1141 tccctccacc ctgcccagat gctggggctg gagaagacca aggggagcct ggactttggt
     1201 gctgatgcag actttgtggt gctcgacgac actctccatg tccaggccac ttacatctct
     1261 ggtgaattgg tgtggcaggc agaggaagct gggccgtgac tgagggtctt ggctggaaag
     1321 gacacttgga gaggccaggc agtccacgga gctggtctcc agggagcaag ctgagagccc
     1381 tgccctatgt ctaaaacaga acctcagtca tcactcctgg aggggaggca gtggcttgga
     1441 taaatacaga cagtgggact tgc
//
