LOCUS       NM_007444               3201 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus S-adenosylmethionine decarboxylase 2 (Amd2), mRNA.
ACCESSION   NM_007444 XM_001476532
VERSION     NM_007444.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Sah,R.K., Yang,A., Bah,F.B., Adlat,S., Bohio,A.A., Oo,Z.M.,
            Wang,C., Myint,M.Z.Z., Bahadar,N., Zhang,L., Feng,X. and Zheng,Y.
  TITLE     Transcriptome profiling of mouse brain and lung under Dip2a
            regulation using RNA-sequencing
  JOURNAL   PLoS One 14 (7), e0213702 (2019)
   PUBMED   31291246
  REMARK    Erratum:[PLoS One. 2019 Nov 14;14(11):e0225570. doi:
            10.1371/journal.pone.0225570.. PMID: 31725791]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3201)
  AUTHORS   Jung,H., Park,H., Choi,Y., Kang,H., Lee,E., Kweon,H., Roh,J.D.,
            Ellegood,J., Choi,W., Kang,J., Rhim,I., Choi,S.Y., Bae,M.,
            Kim,S.G., Lee,J., Chung,C., Yoo,T., Park,H., Kim,Y., Ha,S.,
            Um,S.M., Mo,S., Kwon,Y., Mah,W., Bae,Y.C., Kim,H., Lerch,J.P.,
            Paik,S.B. and Kim,E.
  TITLE     Sexually dimorphic behavior, neuronal activity, and gene expression
            in Chd8-mutant mice
  JOURNAL   Nat Neurosci 21 (9), 1218-1228 (2018)
   PUBMED   30104731
REFERENCE   3  (bases 1 to 3201)
  AUTHORS   Persson,K., Heby,O. and Berger,F.G.
  TITLE     The functional intronless S-adenosylmethionine decarboxylase gene
            of the mouse (Amd-2) is linked to the ornithine decarboxylase gene
            (Odc) on chromosome 12 and is present in distantly related species
            of the genus Mus
  JOURNAL   Mamm Genome 10 (8), 784-788 (1999)
   PUBMED   10430664
REFERENCE   4  (bases 1 to 3201)
  AUTHORS   Nishimura,K., Liisanantti,M., Muta,Y., Kashiwagi,K., Shirahata,A.,
            Janne,M., Kankare,K., Janne,O.A. and Igarashi,K.
  TITLE     Structure and activity of mouse S-adenosylmethionine decarboxylase
            gene promoters and properties of the encoded proteins
  JOURNAL   Biochem J 332 (Pt 3) (Pt 3), 651-659 (1998)
   PUBMED   9620866
REFERENCE   5  (bases 1 to 3201)
  AUTHORS   Persson,K., Holm,I. and Heby,O.
  TITLE     Cloning and sequencing of an intronless mouse S-adenosylmethionine
            decarboxylase gene coding for a functional enzyme strongly
            expressed in the liver
  JOURNAL   J Biol Chem 270 (10), 5642-5648 (1995)
   PUBMED   7890685
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC147238.3.
            
            On or before Feb 22, 2008 this sequence version replaced
            XM_001476532.1, NM_007444.2.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            to make the sequence consistent with the reference genome assembly.
            The transcript and the encoded protein are based on published data
            (PMID:7890685).
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3201              AC147238.3         41481-44681         c
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 19.13 cM"
     gene            1..3201
                     /gene="Amd2"
                     /gene_synonym="AdoMetDC; Amd1; Amd3"
                     /note="S-adenosylmethionine decarboxylase 2"
                     /db_xref="GeneID:100041585"
                     /db_xref="MGI:MGI:1333111"
     exon            1..3201
                     /gene="Amd2"
                     /gene_synonym="AdoMetDC; Amd1; Amd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..1337
                     /gene="Amd2"
                     /gene_synonym="AdoMetDC; Amd1; Amd3"
                     /EC_number="4.1.1.50"
                     /note="adenosylmethionine decarboxylase 2; SAMDC 2;
                     adoMetDC 2; S-adenosylmethionine decarboxylase proenzyme
                     1; AdoMetDC 1; SAMDC 1"
                     /codon_start=1
                     /product="S-adenosylmethionine decarboxylase proenzyme 2"
                     /protein_id="NP_031470.3"
                     /db_xref="CCDS:CCDS48536.1"
                     /db_xref="GeneID:100041585"
                     /db_xref="MGI:MGI:1333111"
                     /translation="MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLL
                     KDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYS
                     GFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLY
                     TLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVI
                     DATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDHLIRKVVEVFK
                     PGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
                     "
ORIGIN      
        1 gcttacacag tatggccggc gacattagct agcgctcgct caactctcct aacgggaaag
       61 cagcggacta caagagactg aactgtatct gcctctattt ccaacagact cacgttcaac
      121 tttcgctcac gaaaatagcc gggaaaattt tattagtcct tttttaaaaa aaaaagttaa
      181 tataaaatta tagcaaaaaa aaaaaaaaaa aaaggaacct gaactttagt aacacagctg
      241 gaacaatccg cagcggcggc aggagcggcg ggagaagaga tttaatttag ttgattttct
      301 gtggttgttg gttgttcgct agtctcacgg tgatggaagc tgcacatttt ttcgaaggga
      361 cggagaaact gctggaggtc tggttttcca gacagcagtc cgacgcaagc cagggatctg
      421 gggatcttcg taccatccca agatctgaat gggatgtcct tttgaaggat gtgcagtgct
      481 caatcataag tgtgacaaag actgacaagc aggaagctta tgtactcagt gagagtagca
      541 tgtttgtctc caagagacgt ttcattttga agacatgtgg taccaccctc ttactgaaag
      601 cactggttcc cctgttgaag cttgctaggg attacagtgg gtttgactca attcaaagct
      661 tcttttattc tcgtaagaat ttcatgaagc cttctcacca agggtaccca caccggaatt
      721 tccaggaaga aatcgagttt cttaatgcaa ttttcccaaa tggagcagca tattgtatgg
      781 gacgcatgaa ttctgactgc tggtacttgt atactttgga tttcccagag agccgagtaa
      841 tcagtcagcc agatcaaaca ctggaaattc tgatgagtga gcttgaccca gcagttatgg
      901 accagttcta catgaaagat ggtgttactg caaaggatgt cactcgtgag agtggaattc
      961 gtgacctgat accaggttct gtcattgatg ccacactgtt caatccttgt ggctactcga
     1021 tgaatggaat gaaatcggat ggaacatatt ggactattca catcactcca gaaccagaat
     1081 tttcttatgt tagctttgaa acaaacctaa gtcagacctc ctatgaccac ctgatcagga
     1141 aagttgtgga agtcttcaag ccaggaaaat ttgtgaccac cttgtttgtt aatcagagtt
     1201 ctaaatgtcg cacagtgctt tcttcgcccc agaagattga cggctttaaa cgtcttgatt
     1261 gccagagtgc tatgttcaac gattacaatt ttgtttttac cagttttgct aagaaacagc
     1321 aacaacagca gagttgatta ggaaaaatga agaagaaaaa acgcaaaaag agaagacaca
     1381 caggaggtgg tggctgcttt ctagatgctg atcctgaggg ccatgctgac catgaccacc
     1441 acctcgtagt tgcagaaagc cctaggtgta atgatagtgt aatcattttg aagtgtatgc
     1501 attattatat caaggagtta ggtatcttgc atgaatgctc tcttctgtgt ttaggtgttc
     1561 tatgccactc ttgctgtgga actgaagtgc atgtagaaaa gacctttgac tgtatgaatc
     1621 tttacgacac ttgtgaaaat gatacaattt ggtttatgca cagtgtaata tttctgcagg
     1681 catcatccaa aattccccac agacaaggct ttcgtcccca ttagatgcgg cctcagctga
     1741 catctgtgac tgttctatta aattgctgcc agagttttta catccagtta cctccacttt
     1801 ctagggcata ttctctacta atgttactca aaaccaattt ctacttcata caggtgtttt
     1861 atgcaatggc aattaaagtt tttcttccac aagttgagtc tttgtaagaa aatgactcca
     1921 gttgcttgtt ttatgttctg ctgttttaat aattgctcct gcatttagag tcctatagtt
     1981 tttccaccac ctttgatgaa gcaatacact gttacactgt gggcttatat tataatttta
     2041 caccccaggt gagagtttgg agatggtccc ttgcttaatt ttttttccta agacataaga
     2101 atgtggtctc tttattggca tgaacttctg tggaagataa atgacaaaac tgaatgtatc
     2161 aaatgaaaag aactcacagt ctccagggcg atgagcaagg agaacccatt aaagaaaact
     2221 ccatggaaat gataggctgt gcagtgcacc ttaattagcg ttaatggagt gcctactatg
     2281 ccctcactaa tttactaaat gataggaatg tccactatgt caaagcagaa atgtagtcct
     2341 agcattctga cctcagtaag tgctgccgtt gccaccaggt tttatttact aaaggagatt
     2401 ttgattcgaa ggagaatctg gtttctactt gtcctgccgt cggctggtct ctggtcttcc
     2461 tttcaccgtg gccttcagat gatcagatga atgactgacc agagggagga ggcctctcca
     2521 ggttactcag ccaaatagtg aatgtatgaa tggatggaac ggcgcaatat tctgaatcta
     2581 tttaatggca ctagaaataa tgggcgttga agagtcggca tgttggtggg acttaaacag
     2641 aaaagagcaa actggactaa actccctatt tattgccctc ctgttttctt ggtagtttct
     2701 ggactgatgc agtgatgttt tgttccttcc gtatttataa cgaaacactt ttttagcgtt
     2761 tctaaacaga gtctacttgg tttgagatca agtggttgga acactgtctg gactctttct
     2821 acacggtgtt gattgaaggc ttctttgggg aagctttcgg tcagctttat ctgtctgatt
     2881 ctgtaatgag cacagcacct attttgaatt gctatttgga gggccagtgc ttatttaagc
     2941 tggattttgt aacccagtag attttggctt gaggtctgat ttccccgtct taaattaaga
     3001 atcctaatgt tgagaattgc ataggtttgt gtggaacaaa gcctagaaca actgtaggta
     3061 aactagtgat ctagtctaat tacaggtggg gaagttttgg tgccataatt tctctttgtt
     3121 ggtgttggac ttttaatcag ctgaaatgta tttctgtacc acaatgtaag cttcaataaa
     3181 agtttgctta attgtctagt a
//
