LOCUS       NM_007439               5918 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus anaplastic lymphoma kinase (Alk), mRNA.
ACCESSION   NM_007439 XM_917918 XM_925350
VERSION     NM_007439.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5918)
  AUTHORS   Korai,A., Lin,X., Tago,K. and Funakoshi-Tago,M.
  TITLE     The acetylation of STAT3 at K685 attenuates NPM-ALK-induced
            tumorigenesis
  JOURNAL   Cell Signal 114, 110985 (2024)
   PUBMED   38000524
  REMARK    GeneRIF: The acetylation of STAT3 at K685 attenuates
            NPM-ALK-induced tumorigenesis.
REFERENCE   2  (bases 1 to 5918)
  AUTHORS   Christova,T., Ho,S.K., Liu,Y., Gill,M. and Attisano,L.
  TITLE     LTK and ALK promote neuronal polarity and cortical migration by
            inhibiting IGF1R activity
  JOURNAL   EMBO Rep 24 (7), e56937 (2023)
   PUBMED   37291945
  REMARK    GeneRIF: LTK and ALK promote neuronal polarity and cortical
            migration by inhibiting IGF1R activity.
REFERENCE   3  (bases 1 to 5918)
  AUTHORS   Van de Velde,L.A., Allen,E.K., Crawford,J.C., Wilson,T.L.,
            Guy,C.S., Russier,M., Zeitler,L., Bahrami,A., Finkelstein,D.,
            Pelletier,S., Schultz-Cherry,S., Thomas,P.G. and Murray,P.J.
  TITLE     Neuroblastoma Formation Requires Unconventional CD4 T Cells and
            Arginase-1-Dependent Myeloid Cells
  JOURNAL   Cancer Res 81 (19), 5047-5059 (2021)
   PUBMED   34301764
REFERENCE   4  (bases 1 to 5918)
  AUTHORS   Gao,A., Tang,H., Zhang,Q., Liu,R., Wang,L., Liu,Y., Qi,Z. and
            Shen,Y.
  TITLE     Mst1/2-ALK promotes NLRP3 inflammasome activation and cell
            apoptosis during Listeria monocytogenes infection
  JOURNAL   J Microbiol 59 (7), 681-692 (2021)
   PUBMED   33877580
  REMARK    GeneRIF: Mst1/2-ALK promotes NLRP3 inflammasome activation and cell
            apoptosis during Listeria monocytogenes infection.
REFERENCE   5  (bases 1 to 5918)
  AUTHORS   Murakami,K., Terakado,Y., Saito,K., Jomen,Y., Takeda,H., Oshima,M.
            and Barker,N.
  TITLE     A genome-scale CRISPR screen reveals factors regulating
            Wnt-dependent renewal of mouse gastric epithelial cells
  JOURNAL   Proc Natl Acad Sci U S A 118 (4) (2021)
   PUBMED   33479180
  REMARK    GeneRIF: A genome-scale CRISPR screen reveals factors regulating
            Wnt-dependent renewal of mouse gastric epithelial cells.
REFERENCE   6  (bases 1 to 5918)
  AUTHORS   Morris,S.W., Naeve,C., Mathew,P., James,P.L., Kirstein,M.N., Cui,X.
            and Witte,D.P.
  TITLE     ALK, the chromosome 2 gene locus altered by the t(2;5) in
            non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine
            kinase that is highly related to leukocyte tyrosine kinase (LTK)
  JOURNAL   Oncogene 14 (18), 2175-2188 (1997)
   PUBMED   9174053
  REMARK    Erratum:[Oncogene 1997 Dec 4;15(23):2883]
REFERENCE   7  (bases 1 to 5918)
  AUTHORS   Iwahara,T., Fujimoto,J., Wen,D., Cupples,R., Bucay,N., Arakawa,T.,
            Mori,S., Ratzkin,B. and Yamamoto,T.
  TITLE     Molecular characterization of ALK, a receptor tyrosine kinase
            expressed specifically in the nervous system
  JOURNAL   Oncogene 14 (4), 439-449 (1997)
   PUBMED   9053841
REFERENCE   8  (bases 1 to 5918)
  AUTHORS   Mathew,P., Morris,S.W., Kane,J.R., Shurtleff,S.A., Pasquini,M.,
            Jenkins,N.A., Gilbert,D.J. and Copeland,N.G.
  TITLE     Localization of the murine homolog of the anaplastic lymphoma
            kinase (AlK) gene on mouse chromosome 17
  JOURNAL   Cytogenet Cell Genet 70 (1-2), 143-144 (1995)
   PUBMED   7736780
REFERENCE   9  (bases 1 to 5918)
  AUTHORS   Baniyash,M., Hsu,V.W., Seldin,M.F. and Klausner,R.D.
  TITLE     The isolation and characterization of the murine T cell antigen
            receptor zeta chain gene
  JOURNAL   J Biol Chem 264 (22), 13252-13257 (1989)
   PUBMED   2787796
REFERENCE   10 (bases 1 to 5918)
  AUTHORS   Fujita,N., Sato,S., Kurihara,T., Inuzuka,T., Takahashi,Y. and
            Miyatake,T.
  TITLE     Developmentally regulated alternative splicing of brain
            myelin-associated glycoprotein mRNA is lacking in the quaking mouse
  JOURNAL   FEBS Lett 232 (2), 323-327 (1988)
   PUBMED   2454205
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK051358.1, D83002.1, AC154458.2 and BE652096.1.
            
            On Jul 14, 2006 this sequence version replaced NM_007439.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849375, SAMN00849376
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1892              AK051358.1         2-1893
            1893-3167           D83002.1           1745-3019
            3168-3168           AC154458.2         128510-128510       c
            3169-3822           D83002.1           3021-3674
            3823-3824           AC154458.2         122146-122147       c
            3825-4833           D83002.1           3677-4685
            4834-5098           BE652096.1         184-448
            5099-5918           AC154458.2         93184-94003         c
FEATURES             Location/Qualifiers
     source          1..5918
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 43.77 cM"
     gene            1..5918
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /note="anaplastic lymphoma kinase"
                     /db_xref="GeneID:11682"
                     /db_xref="MGI:MGI:103305"
     exon            1..1280
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     CDS             599..5464
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /EC_number="2.7.10.1"
                     /note="ALK tyrosine kinase receptor"
                     /codon_start=1
                     /product="ALK tyrosine kinase receptor precursor"
                     /protein_id="NP_031465.2"
                     /db_xref="CCDS:CCDS37688.1"
                     /db_xref="GeneID:11682"
                     /db_xref="MGI:MGI:103305"
                     /translation="MGAAGFLWLLPPLLLAAASYSGAATDQRAGSPASGPPLQPREPL
                     SYSRLQRKSLAVDFVVPSLFRVYARDLLLPQPRSPSEPEAGGLEARGSLALDCEPLLR
                     LLGPLPGISWADGASSPSPEAGPTLSRVLKGGSVRKLRRAKQLVLELGEETILEGCIG
                     PPEEVAAVGILQFNLSELFSWWILHGEGRLRIRLMPEKKASEVGREGRLSSAIRASQP
                     RLLFQIFGTGHSSMESPSETPSPPGTFMWNLTWTMKDSFPFLSHRSRYGLECSFDFPC
                     ELEYSPPLHNHGNQSWSWRHVPSEEASRMNLLDGPEAEHSQEMPRGSFLLLNTSADSK
                     HTILSPWMRSSSDHCTLAVSVHRHLQPSGRYVAQLLPHNEAGREILLVPTPGKHGWTV
                     LQGRVGRPANPFRVALEYISSGNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNG
                     TVLQLGQACDFHQDCAQGEDEGQLCSKLPAGFYCNFENGFCGWTQSPLSPHMPRWQVR
                     TLRDAHSQGHQGRALLLSTTDILASEGATVTSATFPAPMKNSPCELRMSWLIRGVLRG
                     NVSLVLVENKTGKEQSRTVWHVATDEGLSLWQHTVLSLLDVTDRFWLQIVTWWGPGSR
                     ATVGFDNISISLDCYLTISGEEKMSLNSVPKSRNLFEKNPNKESKSWANISGPTPIFD
                     PTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGVQIWKVPATDTYSI
                     SGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPRANQLIQKVC
                     VGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAK
                     TETFHPERLESNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAM
                     KKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFISPLGILYTP
                     ALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT
                     PEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLR
                     TSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDP
                     SPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMA
                     GGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT
                     CPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFG
                     VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP
                     NFAIILERIEYCTQDPDVINTALPIEYGPVVEEEEKVPMRPKDPEGMPPLLVSPQPAK
                     HEEASAAPQPAALTAPGPSVKKPPGAGAGAGAGAGAGPVPRGAADRGHVNMAFSQPNP
                     PPELHKGPGSRNKPTSLWNPTYGSWFTEKPAKKTHPPPGAEPQARAGAAEGGWTGPGA
                     GPRRAEAALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQQQGLPLEATAAPGDTML
                     KSKNKVTQPGP"
     exon            1281..1397
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..1562
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1764
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1892
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..2024
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2025..2156
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2257
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2258..2427
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2428..2522
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..2651
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2814
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2815..2965
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            2966..3097
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3098..3242
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3243..3425
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3426..3524
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3525..3677
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3678..3782
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3783..3969
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            3970..4060
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4061..4125
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4126..4255
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4256..4353
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4354..4446
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4447..4548
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4549..4683
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4684..4774
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
     exon            4775..5918
                     /gene="Alk"
                     /gene_synonym="CD246; Tcrz"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgttcacgc ccagaagttc agcgggcagg gtgatcgatc cgaagacttc ctgcagcgga
       61 ggtcacttga gggggcgcta gaaagcagcc ccctccggtg gtccttgcct agacctggga
      121 aggagcgcag aggaggtgac aggagcggag gacgtgggca agacagtgac cgactcggag
      181 ccacggttca cagcctggaa agttgcagaa gattggaagc taagaggaga gctctggtcg
      241 ccgagggctc cttgaacggt acctaattgc cacctccctg gtccctgagc aaaggcctct
      301 acaaatgggg cgcagcacgg cgagaggcgc aggatccagc tgttgagccc agggtgtctc
      361 actgtctccg aactaccccc tgactttgtc ttccgttttg ctgagaaccc ttctcgcctc
      421 cttgtagctt gggaaaagca agggcgctct atagtgtaca cacagtccct gagatctagt
      481 ggaaggagcc attcaggacc aaggactatt tggagccctt tcctgtttgg gggagagtga
      541 agggcgaggc tggaccagca agggaaggga gactagtgta aactcgccct ccagcgggat
      601 gggagctgct gggttcctgt ggctgctgcc tccactgctt ttggcagcag cctcgtactc
      661 cggagctgca accgatcagc gcgcgggttc cccagcctca gggcctcctc tgcagccccg
      721 ggagccgctc agttattcgc gcctgcagag gaagagtctg gcagtggact tcgttgtacc
      781 ctcgctcttc cgcgtctatg cccgagacct gctgctaccg cagccacggt ccccctcgga
      841 gcccgaggct ggcgggctgg aggcgcgggg atcactggcc ctggattgtg agcctctgct
      901 caggctgctg gggccactgc ctggaatctc ctgggcagat ggagccagtt ctcctagtcc
      961 cgaggcgggt ccgacgctgt ccagggtgct gaagggaggc tcggtgcgca agctcaggcg
     1021 tgccaaacag ctggtgctgg agctgggcga ggagacgatt cttgaaggct gtattggtcc
     1081 cccagaggag gtagcggctg tggggatact ccagttcaac ctcagcgagc tgttcagctg
     1141 gtggattctc cacggcgaag ggaggctgag gatccgcctg atgcctgaga agaaggcatc
     1201 ggaagtgggc agggagggaa ggctatccag tgcgatccga gcctcccagc cccgccttct
     1261 cttccagatc ttcgggacgg gacacagctc catggagtca ccctcagaaa cgccttctcc
     1321 tcctggtacc ttcatgtgga atctgacctg gacgatgaaa gactccttcc ctttcctttc
     1381 ccaccgcagt cgatatggtc tggagtgcag ctttgacttc ccctgtgagc tggaatattc
     1441 tcctcccctg cacaaccacg ggaatcagag ctggtcctgg cgccatgtgc cctccgagga
     1501 ggcctcgagg atgaacttgc tggatgggcc agaggcagag cattctcaag agatgcccag
     1561 aggctccttc ctcctcctga acacctctgc agattccaag cataccattc tgagcccatg
     1621 gatgaggagc agtagtgatc actgcacact ggctgtctcc gtgcacagac atctacagcc
     1681 ttcggggaga tatgttgccc agctcctacc ccacaacgaa gctggaagag agattctttt
     1741 ggtgcccacc ccagggaagc atggctggac agtgctgcag gggagagtcg ggcgcccagc
     1801 aaacccattt cgagtggctc tggaatacat ctccagtggc aaccggagct tgtcggcggt
     1861 ggatttcttt gccctgaaga actgcagtga agggacatcc ccaggctcca agatggcatt
     1921 gcagagttcc ttcacttgtt ggaatgggac cgtcctccag ctcgggcaag cctgtgattt
     1981 ccaccaggac tgtgcccaag gagaagatga gggccagctg tgcagtaaac ttcctgctgg
     2041 attttactgt aactttgaaa atggcttctg tggctggacc caaagtccac tctcacccca
     2101 tatgccccgg tggcaagtga ggaccctaag agatgcccat tcccagggcc accaaggccg
     2161 tgccctgttg ctcagcacca ctgacatcct cgcttctgaa ggtgcaacag tgaccagtgc
     2221 caccttccct gcaccaatga aaaattctcc ttgtgagctc cgcatgtcct ggctcatccg
     2281 cggggttttg agaggaaacg tatctctggt gctggtggag aacaaaaccg gaaaggagca
     2341 aagccggact gtctggcatg tcgccactga cgaaggctta agcctgtggc agcatacagt
     2401 gctgtccctc ctcgatgtga ctgacaggtt ctggctgcag atagtcacat ggtggggtcc
     2461 aggatccagg gcaaccgtgg gatttgacaa catttccatc agcctcgact gctaccttac
     2521 catcagtgga gaggagaaaa tgtccctgaa ttcagtaccc aaatctagaa atctgtttga
     2581 gaaaaaccca aacaaggagt caaaatcctg ggcaaacata tcaggaccaa ctcccatctt
     2641 cgaccctaca gttcactggc tgttcaccac gtgtggggcc agtggacctc atggccccac
     2701 ccaggcacag tgcaacaacg cctaccagaa ttccaacttg agcgtggtgg tgggaagtga
     2761 agggcccttg aagggagtcc agatttggaa agtgccagct actgacacct acagtatctc
     2821 gggctacgga gcagctggcg ggaaaggtgg gaaaaacacc atgatgcggt cccatggcgt
     2881 gtctgtcctg ggcatcttca atctggagaa aggtgacaca ctctacatcc ttgtcggtca
     2941 gcaaggggag gatgcctgtc ccagggcaaa ccaactaatc cagaaagtct gtgtgggtga
     3001 gaacaatgtc atagaagaag agatccgagt gaacagaagc gtgcacgagt gggcaggagg
     3061 aggaggaggt gggggtggag ccacctacgt gtttaagatg aaagatggcg tgcctgtacc
     3121 cctgatcatt gcagctggtg gtggtggcag ggcctatggg gccaagacag aaacgttcca
     3181 cccagagaga ctggagagta actcctcggt tctagggctg aacggcaatt ccggagccgc
     3241 aggtggtgga ggcggctgga atgataacac ttccttgctc tgggccggaa agtctttgct
     3301 ggagggtgcc gccggaggac attcctgccc ccaggccatg aagaagtggg ggtgggagac
     3361 aagagggggt ttcggagggg gtggaggggg gtgctcctca ggtggaggag gcggaggata
     3421 tataggtggc aacgcagcat caaacaatga ccccgaaatg gatggggaag atggggtttc
     3481 cttcatcagt ccattgggta tcctgtacac cccggcctta aaagtgatgg agggccacgg
     3541 ggaagtgaat atcaagcatt atctaaactg cagtcactgc gaggtagacg aatgtcacat
     3601 ggaccccgag agccacaaag tcatctgctt ctgtgatcat gggaccgtgc tggctgatga
     3661 tggtgtctcc tgcattgtgt cacccacccc ggagccccac ctgccgctct cattgatcct
     3721 ctccgtcgtg acctctgccc tggtggctgc ccttgttctg gcattctccg gcatcatgat
     3781 tgtgtaccgt cggaagcacc aggagttgca ggctatgcag atggaactgc agagccccga
     3841 gtataagctg agcaagctac ggacctcgac catcatgacc gactacaacc ccaactactg
     3901 cttcgctggc aagacttcct ccatcagtga cctgaaagaa gtgccacgga aaaacatcac
     3961 actcatccgg ggcctaggcc atggcgcatt tggggaggtg tatgaaggcc aggtgtctgg
     4021 aatgcccaat gacccaagcc ctctacaagt ggctgtaaag acgctgccag aagtgtgttc
     4081 agaacaagat gagctggact ttctcatgga agctctgatc atcagcaaat tcaaccacca
     4141 gaatattgtt cgctgcatcg gggtgagtct acaagccctg ccccgcttca tcctgctgga
     4201 actcatggct ggcggagacc tcaagtcctt cctcagggag acacgccctc gcccgaacca
     4261 acccacctcc ctggccatgc tggaccttct gcatgtggct cgggacattg cctgtggctg
     4321 tcagtaccta gaggagaatc actttatcca ccgggatatt gctgctagaa actgtctgtt
     4381 gacctgccca ggagctggaa gaatagcaaa gattggagac tttgggatgg cccgagatat
     4441 ctacagggcc agctactacc gaaagggagg ctgcgccatg ctgccggtca agtggatgcc
     4501 ccctgaagcc ttcatggaag ggatatttac ctctaaaaca gacacatggt cttttggagt
     4561 gttgctatgg gaaatatttt ctcttggata tatgccgtac cccagcaaga gcaaccagga
     4621 agttctggag tttgtcacca gcggaggacg gatggacccg cctaagaact gccccgggcc
     4681 tgtataccgg ataatgacgc agtgctggca gcatcagcct gaagacagac ccaacttcgc
     4741 catcattttg gagaggatcg aatactgcac ccaggacccc gatgtgatca acacagctct
     4801 gcccatcgaa tacggtccag tagtagaaga ggaggagaaa gtgcccatgc gccccaaaga
     4861 ccccgagggg atgccacctt tgctggtgtc tccccagcct gcgaagcacg aggaggcgtc
     4921 cgcagctccc cagcccgcag ccctgacggc accaggccca tcggtgaaga agcccccggg
     4981 tgcgggtgcg ggcgcgggcg cgggtgcggg tgccggcccg gtgccccgag gtgcggccga
     5041 tcggggccac gtgaacatgg ctttctctca gcccaaccct cccccggagc tgcacaaagg
     5101 cccgggatcc agaaacaagc cgaccagcct gtggaacccc acctacggct cgtggttcac
     5161 cgagaagcct gccaaaaaga cccatcctcc gccaggcgcc gagccgcagg cgcgggcagg
     5221 agcggccgag ggtggctgga ccgggccggg cgcggggccc cgcagagccg aggcagcgct
     5281 gctgctagag ccatcggcgc tgagcgccac catgaaggag gtgccgctgt tcaggctgcg
     5341 ccacttcccc tgcggcaatg tcaactatgg ttaccagcaa cagggtctcc ccttggaagc
     5401 cacagccgcg ccaggggaca ccatgctgaa aagcaagaat aaggtcaccc agccggggcc
     5461 ctgagccctg tactccacta gcttctcctc ctggcggagc cggagcccac ccagagggag
     5521 atggacagga tggctccacc acaaacccaa gaccaaaact ttcatttttg tgccaacttg
     5581 ttttgaagtg ccacatttta aaaaaaggaa acttgtgttt ttaagatgtg ttagaaggtt
     5641 ttttgagcat gggttcatct atcctctcaa aagaagaaaa tgccattctt taaaaaagaa
     5701 aaaaaagcaa tcagtgcaag gcccagattg gttgcgccaa gttttcgtgc atggtctgct
     5761 gtacagtccc ctaaggcttc tttccgattt ttgtgtgcgc tctgcttccg cgtagtcaga
     5821 aatagctgct tccatgtctc atagggggag tcctaggtgt ttcctttgcc ttatgaatat
     5881 gaaccactcg aggggcgggc gagggaacag aaataaag
//
