LOCUS       NM_024178               2070 bp    mRNA    linear   ROD 16-JUN-2024
DEFINITION  Mus musculus asparagine-linked glycosylation 14 (Alg14), transcript
            variant 1, mRNA.
ACCESSION   NM_024178
VERSION     NM_024178.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2070)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161210.5 and AC105336.14.
            
            On Apr 12, 2018 this sequence version replaced NM_024178.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011733.1, BC002278.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               AC161210.5         52583-52826         c
            245-399             AC161210.5         45808-45962         c
            400-531             AC161210.5         24355-24486         c
            532-2070            AC105336.14        54681-56219
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 52.94 cM"
     gene            1..2070
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /note="asparagine-linked glycosylation 14"
                     /db_xref="GeneID:66789"
                     /db_xref="MGI:MGI:1914039"
     exon            1..244
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..762
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /note="UDP-N-acetylglucosamine transferase subunit ALG14
                     homolog; asparagine-linked glycosylation 14 homolog"
                     /codon_start=1
                     /product="UDP-N-acetylglucosamine transferase subunit
                     ALG14"
                     /protein_id="NP_077140.1"
                     /db_xref="CCDS:CCDS17801.1"
                     /db_xref="GeneID:66789"
                     /db_xref="MGI:MGI:1914039"
                     /translation="MLSILILAATAAGLVILLFQRLWTVLGPHHVTPRESLRLLIVAG
                     SGGHTTEILRLVGSLSNAYSPRHYVIAESDEMSAKKIHSLEELSRAQNDSTTEYPKYH
                     LHRIPRSREVRQSWLSSVFTTFYSMWFSFPLVLRIKPDLVLCNGPGTCVPICVSALLL
                     GILGVKKVIIVYVESICRVETLSLSGKILRHLSDYFIVQWPTLKEKYPKSVYLGRIV"
     exon            245..399
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            400..531
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            532..2070
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      966..971
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      996
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /note="major polyA site"
     regulatory      1913..1918
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1956
                     /gene="Alg14"
                     /gene_synonym="5430428G01Rik"
ORIGIN      
        1 accatccccg cccacagaga ggcgctttgc tccctgtttg ctcttaagcg cggtgcttgc
       61 aaactttaac cgctggcgcc aggtctacac gcatgcgcca tcctttgaat gctgagcatt
      121 ctgattctag ctgctacagc cgcagggcta gtgatcttgc tattccagcg actatggacc
      181 gtgcttgggc cccatcacgt cactccccga gagtctctca gactcttgat cgtggctgga
      241 tccggtggac acaccactga gatcttgagg ctggttggaa gcttgtccaa tgcctattca
      301 ccaaggcatt atgtcattgc tgagtctgat gaaatgagtg ccaagaaaat ccattctctt
      361 gaagaactct ctcgagccca gaatgactct actactgaat accccaagta ccaccttcac
      421 cgaattccga gaagccggga ggttcggcag tcctggctct cctccgtgtt cactaccttc
      481 tactccatgt ggttctcctt cccactggtt ctccgaataa agccagattt ggtgctgtgt
      541 aatggaccag gaacatgcgt ccctatctgt gtgtccgccc tgcttcttgg gatacttgga
      601 gtgaagaaag tgatcatcgt ctatgtcgag agcatctgcc gagtggagac gctatccctg
      661 tcagggaaga tcctgaggca cctctccgac tacttcattg ttcagtggcc cactctcaag
      721 gagaagtacc ccaagtctgt gtacctgggg cgaattgttt gacaaatggc aaccctaagt
      781 cttgagaaca ttacaagtac cgataatatt tactatatac tatctttact ataaagtttt
      841 tcaaaggtca aggaaatatc aatggtaaag aatttaaaat gtacaaataa ctcaatgaag
      901 aaagacaaac tttagcatat aatacccatc aagtagctat gtctgcacac gaaaacattt
      961 ttctaaataa aagtacatat aacactacta acactactca caggttctct tgggactctt
     1021 tgtttgtttg tttgttttta atggttttag agctttattg tagaaaggta gggataaaga
     1081 gagaaggtaa aaagagggag agaggccagc cctggccacg tggagagagg gggaagggag
     1141 agagagaagg agggctctac agagatgaga gtaagaaagg tgagagcttt aaaagctctc
     1201 ttgggactct tacagctgtg gggttttagt ttggtttttt tttttttttt ctcttaacct
     1261 aaatatagag tgtgtatgtt tagtaacatt tcctgtttta cagctttaaa taaaacaaaa
     1321 gtgttctcca ttataaaaag aaagtacagg ataaggcagg ttggaggcag gtattatcag
     1381 tgtgatccct ctctcaggag gcgagggagg aggatcagga gttgttggtg taaggagtgg
     1441 ggacagggaa gtaaggaaaa gggggttgct taagagcaag gcatcccttt ggtcctgttc
     1501 agacttgtca ggctttactc cttctgggga agcctcttag tgagctatct cagcctaaag
     1561 gaagcatgag ctatctcagc ctaaaggaag catgagctat ctcagcctaa aggaagcatg
     1621 agctatctca gcctaaagga agcatgagct atctcagcct aaaggaagca agagctatct
     1681 cagcctaaag gactcatgag ctatctcagc ctaaaggaag caagagctat ctcagcataa
     1741 aggaagcagt ttgttaaact ggtttcatgt ccatttacac tccacagact tccagatctc
     1801 tgactgtaaa caagagtctt tctttattct tcagtctgct tgatgtgttg ttggcctgga
     1861 tccagactgt attttaatat ctgtttggtt aaaatattgg cagtgtcttc ataataaatg
     1921 tatgattcta ttggtcagga atctaaattt tcaaaacatg aagaaaaagc ttttttttcc
     1981 cccaatggct gtaattgtct ctagcttttt gagatgctta tgtctgcctg gtggagggtg
     2041 tattaataaa catttatgta gtgcttgctg
//
