LOCUS       NM_001033441            3727 bp    mRNA    linear   ROD 30-DEC-2022
DEFINITION  Mus musculus asparagine-linked glycosylation 10B
            (alpha-1,2-glucosyltransferase) (Alg10b), mRNA.
ACCESSION   NM_001033441 XM_354869 XM_894966 XM_902214 XM_913778 XM_922897
            XM_922905
VERSION     NM_001033441.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3727)
  AUTHORS   Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK,
            Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L,
            Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre
            JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A,
            Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ,
            Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall
            S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA,
            Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR,
            Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana
            S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, MacArthur DG,
            Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC,
            Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL,
            de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown
            SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M and Murray
            SA.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   2  (bases 1 to 3727)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3727)
  AUTHORS   Probst FJ, Corrigan RR, Del Gaudio D, Salinger AP, Lorenzo I, Gao
            SS, Chiu I, Xia A, Oghalai JS and Justice MJ.
  TITLE     A point mutation in the gene for asparagine-linked glycosylation
            10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus
            musculus)
  JOURNAL   PLoS One 8 (11), e80408 (2013)
   PUBMED   24303013
  REMARK    GeneRIF: A point mutation in the gene for asparagine-linked
            glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment
            in mice.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3727)
  AUTHORS   Kile BT, Hentges KE, Clark AT, Nakamura H, Salinger AP, Liu B, Box
            N, Stockton DW, Johnson RL, Behringer RR, Bradley A and Justice MJ.
  TITLE     Functional genetic analysis of mouse chromosome 11
  JOURNAL   Nature 425 (6953), 81-86 (2003)
   PUBMED   12955145
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC158922.8.
            
            [WARNING] On Apr 17, 2023 this sequence was replaced by
            NM_001033441.4.
            
            On May 2, 2007 this sequence version replaced NM_001033441.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147821.1, AK170450.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               AC158922.8         150870-151167       c
            299-496             AC158922.8         149624-149821       c
            497-3727            AC158922.8         144924-148154       c
FEATURES             Location/Qualifiers
     source          1..3727
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15"
     gene            1..3727
                     /gene="Alg10b"
                     /gene_synonym="Deaf1; Gm917; nse5"
                     /note="asparagine-linked glycosylation 10B
                     (alpha-1,2-glucosyltransferase)"
                     /db_xref="GeneID:380959"
                     /db_xref="MGI:MGI:2146159"
     exon            1..298
                     /gene="Alg10b"
                     /gene_synonym="Deaf1; Gm917; nse5"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1552
                     /gene="Alg10b"
                     /gene_synonym="Deaf1; Gm917; nse5"
                     /EC_number="2.4.1.256"
                     /note="potassium channel regulator 1; putative
                     alpha-1,2-glucosyltransferase ALG10-B;
                     alpha-2-glucosyltransferase ALG10-B; asparagine-linked
                     glycosylation protein 10 homolog B;
                     alpha-1,2-glucosyltransferase ALG10-A; asparagine-linked
                     glycosylation 10 homolog B (yeast,
                     alpha-1,2-glucosyltransferase)"
                     /codon_start=1
                     /product="putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol
                     alpha-1,2-glucosyltransferase"
                     /protein_id="NP_001028613.1"
                     /db_xref="CCDS:CCDS27757.1"
                     /db_xref="GeneID:380959"
                     /db_xref="MGI:MGI:2146159"
                     /translation="MAQLEGYYFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQ
                     AQRYCEGRFSLSQWDPMITTLPGLYLVSVGVVKPASWLLGWSEHVICSIGVLRFVNLL
                     FSVGNFYLLYLLFRKVQPRNKASSSIQRILSTLTLAVFPTLYFFNFLYYTEAGSVFFT
                     LFAYLMCLYGNHRTSALLGFCGFMFRQTNIIWAAFCAGHLIAQKCSEAWKIELQKKKE
                     ERLAPTKGPLSELRRVLQFLLVYAMSLKNLRMLFLLTWPYVLLLLAFFAFVVVNGGIV
                     VGDRSSHEACLHFPQLFYFFSFTAFFSFPHLLSLTKVKTFLSLVWKRRVQFSVVTLVS
                     ILLVWKFTYVHKYLLADNRHYTFYVWKRVFQRHEVVKYLLVPAYIFAGWAIADSLKAK
                     SIFWNLMFFVCLVASTVPQKLLEFRYFILPYIIYRLNIPLPPISRLVCELGCYTVVNF
                     VTFYIFLNKTFQWPNSQDIQRFMW"
     exon            299..496
                     /gene="Alg10b"
                     /gene_synonym="Deaf1; Gm917; nse5"
                     /inference="alignment:Splign:2.1.0"
     exon            497..3727
                     /gene="Alg10b"
                     /gene_synonym="Deaf1; Gm917; nse5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgtcctgtt ccctgctgtc cctcgtcccg cagcgctggg cctctgagcc cgcgttccgg
       61 gctcggcgct ccgggctgcc cagggctggg cccgggacgc ggctgcccgc ccgcccgccc
      121 gcccgccatg gcgcagctgg agggctatta cttctcggcc gccttgagct gcaccttcct
      181 ggtgtcctgc ctgctcttct ccgccttcag ccgcgctctg cgggagccgt acatggacga
      241 gatcttccac ctgccgcagg cgcagcggta ctgcgagggc cgcttctccc tgtcgcagtg
      301 ggatcctatg atcactacat tacctggcct gtatctggtg tcggtcggtg tggtcaaacc
      361 tgccagctgg ctccttggat ggtctgagca tgtgatctgc tccattgggg tgctcagatt
      421 tgtcaatctt ctcttcagcg ttggcaactt ctacttgctg tatttgctct tcaggaaggt
      481 gcaacccaga aacaaggctt cttcaagtat ccagagaatc ttgtcaacat taaccctagc
      541 agtgtttcca accctctatt tttttaactt cctttactat acagaagctg ggtctgtatt
      601 cttcactctt tttgcttatt tgatgtgtct ttatggcaac cataggacct cggccttgct
      661 tggattttgt ggtttcatgt ttcgtcagac caacatcatc tgggcggcct tctgtgcagg
      721 acacctcatt gcacagaagt gcagtgaagc ctggaagatt gagctgcaga agaagaagga
      781 ggagaggctt gcgcccacga agggaccgct ctcggagctc agaagagtgc tgcagtttct
      841 gctggtgtac gccatgtccc taaagaacct gagaatgctc ttcctgttga cctggcccta
      901 cgtgcttctg ctgttggcgt tctttgcctt tgtggtagtt aatggtggca ttgttgttgg
      961 tgaccggagt agtcacgagg cctgtctcca ttttcctcag ttgttctatt tcttctcctt
     1021 tactgccttt ttctccttcc ctcacctact ttctctgacc aaagtcaaga ctttccttag
     1081 cttagtttgg aagcgtagag tccagttctc tgtggttacg ttagtctcga tacttttggt
     1141 ttggaaattc acttatgtcc ataagtattt actggcagac aataggcatt acacatttta
     1201 tgtgtggaaa agagtatttc agagacatga agttgtcaaa tatttattag ttccagccta
     1261 catttttgct ggttgggcta tagctgactc tttaaaggct aagtcaattt tctggaattt
     1321 aatgtttttt gtatgcttgg ttgcttctac agttcctcag aaactactag aattccgtta
     1381 cttcattcta ccatacatta tttataggct taacatacct ctgccaccca tatctagact
     1441 cgtttgtgaa ctgggttgct atacagttgt taattttgta actttttata tctttctgaa
     1501 caagactttt cagtggccaa atagtcagga catccaaagg tttatgtggt agtggtagga
     1561 ataatttgaa ctttaaaaga ctgtttctac aacaagtaac tgggtaaata gaagtggaat
     1621 ttcttttgag taaatccagg gaagtgagta gaattaagtt tgagactagc ctaaaagctc
     1681 tgaatagtag gaataaagtt gcttgcagtt gtcgtgagag tcttttcagc gtttggggaa
     1741 cttttctgtg tgtgtataga tttagggggc tgggtaagct gtgcagggct tgaacttact
     1801 caccaactct cttttgtaaa gaacagcaag taagttgaaa accacttaca aataaatgac
     1861 ccagcagtat ttctgagtga aattgccaga tattgtcgta cccacagctc cgatcttaga
     1921 atagatgcac atatgtaaca aatagtgcat tggaggcttt gggctaagag acaggtgttt
     1981 taatttaggg catagaagtg atgatagcat ttgaactaat tccttatttg cagtttatgc
     2041 aggccaaaga taaactgtgt tgattataat actttttatg gattatcttc tgaaacaatg
     2101 ccctgttagt tatccaggct cctacacaaa accagccaca aaccttctgg cttcagggtt
     2161 tctcctcaca tttgtataag ggcacctaaa ctcaagtgtt ggcaacgctc acaggagctg
     2221 agagtccatt gtccctgttt gccccactcc agcactgctt agaggggcct tgcttttgga
     2281 caggtccctc cagtctgtct gtgtctcata ggactgtctc cactggcttc ttgtgcagtt
     2341 aatgccattg ggtttaggga tcctctgatt cagggtagcg ttatctagag acccttgata
     2401 ttatctagaa aatgtttaaa gtaaggcccc attcataggt ctcacatcat tttggtgtgg
     2461 agtgggaggg ggagggggtg tatgtgataa gatgcccttg atgagagctt ttaagtaaaa
     2521 gtttgttttt aattgagaaa caacaaaaaa gccaaatggc caaggtcatg taatttacag
     2581 ttgtccctat tattcaaaac cagaagaact caaaaggtga gagaagtcat tggtttagtt
     2641 tcattttata atttagtgag cagtactagg tgtgactctg gggtttgctt tgtttcgctt
     2701 tcagttctgt gctactgtta taaactatgt ttctgcttta aattttaaaa agaattatca
     2761 agtatttttt tattaggcgt aattgacttt gttggctagt tagtgctcct aaggggctta
     2821 gtggttaaag gcttgggcca ccccttgcag ggacccccgg gggggttcct ggctcctagg
     2881 gcagcacaac cacttacaca tccacctcta gggcacagag tgccgcctct ggctctgcag
     2941 tctcccgtgc tcacctgcat aaaacctcca cccatgcgca tttaagttag aaatgctaac
     3001 aggtcattgt agaccatatc acccgctgaa ggggttgtgg gctctgcatt ctccaccacg
     3061 cttccagtag gatcttttaa agccttcgtg agaacgcccg tcttttgcct gagctgctct
     3121 gcgctcagta ctcagtttca gcagctctac tttatgtgaa catccacagg cctagcctcc
     3181 tctcccagat ctgactttgt gtgcagtgca gtgcgtttgc ttacatttgt gctttctgtg
     3241 gatctgtgct ttccccttat ggctgcatct ccccaaatga tgtggaagta gtggtttata
     3301 tttacactta gtaccttatc ttggaagagg aatttctggt ttcatagaca tctctgtttg
     3361 tcctgttaca agatgcccac tataagcaat gccgcttact tctagggaat ggtttagggt
     3421 acgatgtttc cagtgtggac tggactgact gggcgttatg atcatcacct ttgtctagag
     3481 acgacagaag ggattcacag ctttcattta taattcctag agactgaaca tatcttttag
     3541 gtccagttca aactgtattc agataaaatc atgtttattg tcttagagca attagaaagt
     3601 cttaatgtac ataatatttt tcatagagga aattaaataa gatgtagaaa aaaatgtcct
     3661 tgatttttgg ctccagaata aaaagacaaa ttgttgaagg acggttgttt gttcctaatc
     3721 tcaaatg
//
