LOCUS       NM_009654               2076 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus albumin (Alb), mRNA.
ACCESSION   NM_009654
VERSION     NM_009654.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2076)
  AUTHORS   Ito,J., Nakamura,T., Toyama,T., Chen,D., Berndt,C., Poschmann,G.,
            Mourao,A.S.D., Doll,S., Suzuki,M., Zhang,W., Zheng,J., Trumbach,D.,
            Yamada,N., Ono,K., Yazaki,M., Kawai,Y., Arisawa,M., Ohsaki,Y.,
            Shirakawa,H., Wahida,A., Proneth,B., Saito,Y., Nakagawa,K.,
            Mishima,E. and Conrad,M.
  TITLE     PRDX6 dictates ferroptosis sensitivity by directing cellular
            selenium utilization
  JOURNAL   Mol Cell 84 (23), 4629-4644 (2024)
   PUBMED   39547222
REFERENCE   2  (bases 1 to 2076)
  AUTHORS   Siegerist,F., Kliewe,F., Hammer,E., Schakau,P., Chi Soh,J.E.,
            Weber,C., Lindenmeyer,M., Reichelt-Wurm,S., Drenic,V.,
            Chatziantoniou,C., Chadjichristos,C.E., Zhang,Y., Simm,S.,
            Banas,M.C., Nauck,M., Volker,U. and Endlich,N.
  TITLE     The role of the tricellular junction protein ILDR2 in
            glomerulopathies: Expression patterns and functional insights
  JOURNAL   iScience 27 (12), 111329 (2024)
   PUBMED   39640577
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2076)
  AUTHORS   Stark,K., Kilani,B., Stockhausen,S., Busse,J., Schubert,I.,
            Tran,T.D., Gaertner,F., Leunig,A., Pekayvaz,K., Nicolai,L.,
            Fumagalli,V., Stermann,J., Stephan,F., David,C., Muller,M.B.,
            Heyman,B., Lux,A., da Palma Guerreiro,A., Frenzel,L.P.,
            Schmidt,C.Q., Dopler,A., Moser,M., Chandraratne,S., von Bruhl,M.L.,
            Lorenz,M., Korff,T., Rudelius,M., Popp,O., Kirchner,M., Mertins,P.,
            Nimmerjahn,F., Iannacone,M., Sperandio,M., Engelmann,B.,
            Verschoor,A. and Massberg,S.
  TITLE     Antibodies and complement are key drivers of thrombosis
  JOURNAL   Immunity 57 (9), 2140-2156 (2024)
   PUBMED   39226900
REFERENCE   4  (bases 1 to 2076)
  AUTHORS   Feola,K., Venable,A.H., Broomfield,T., Villegas,M., Fu,X.,
            Burgess,S. and Huen,S.C.
  TITLE     Hepatic ketogenesis is not required for starvation adaptation in
            mice
  JOURNAL   Mol Metab 86, 101967 (2024)
   PUBMED   38876267
REFERENCE   5  (bases 1 to 2076)
  AUTHORS   Miura,S., Horisawa,K., Iwamori,T., Tsujino,S., Inoue,K.,
            Karasawa,S., Yamamoto,J., Ohkawa,Y., Sekiya,S. and Suzuki,A.
  TITLE     Hepatocytes differentiate into intestinal epithelial cells through
            a hybrid epithelial/mesenchymal cell state in culture
  JOURNAL   Nat Commun 15 (1), 3940 (2024)
   PUBMED   38750036
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2076)
  AUTHORS   Giometti,C.S., Taylor,J. and Tollaksen,S.L.
  TITLE     Mouse liver protein database: a catalog of proteins detected by
            two-dimensional gel electrophoresis
  JOURNAL   Electrophoresis 13 (12), 970-991 (1992)
   PUBMED   1286668
REFERENCE   7  (bases 1 to 2076)
  AUTHORS   Le Roy,H., Simon-Chazottes,D., Montagutelli,X. and Guenet,J.L.
  TITLE     A set of anonymous DNA clones as markers for mouse gene mapping
  JOURNAL   Mamm Genome 3 (4), 244-246 (1992)
   PUBMED   1351769
REFERENCE   8  (bases 1 to 2076)
  AUTHORS   Lalley,P.A., Minna,J.D. and Francke,U.
  TITLE     Conservation of autosomal gene synteny groups in mouse and man
  JOURNAL   Nature 274 (5667), 160-163 (1978)
   PUBMED   662012
REFERENCE   9  (bases 1 to 2076)
  AUTHORS   Petras,M.L. and MacLaren,I.A.
  TITLE     Structural differences between albumin A and albumin C of the house
            mouse, Mus musculus
  JOURNAL   Biochem Genet 14 (1-2), 67-73 (1976)
   PUBMED   1259705
REFERENCE   10 (bases 1 to 2076)
  AUTHORS   Nichols,E.A., Ruddle,F.H. and Petras,M.L.
  TITLE     Linkage of the locus for serum albumin in the house mouse, Mus
            musculus
  JOURNAL   Biochem Genet 13 (9-10), 551-555 (1975)
   PUBMED   1203054
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BY131635.1, AK131891.1 and
            W41729.1.
            
            On Oct 9, 2015 this sequence version replaced NM_009654.3.
            
            Summary: This gene encodes albumin, an abundant plasma protein
            essential for maintaining oncotic pressure that functions as a
            carrier protein for various molecules such as steriods and fatty
            acids in blood. This gene is primarily expressed in liver where the
            encoded protein undergoes proteolytic processing before secretion
            into the plasma. [provided by RefSeq, Oct 2015].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ011413.1, AK131891.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                BY131635.1         2-28
            28-2060             AK131891.1         1-2033
            2061-2076           W41729.1           386-401
FEATURES             Location/Qualifiers
     source          1..2076
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5"
     gene            1..2076
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /note="albumin"
                     /db_xref="GeneID:11657"
                     /db_xref="MGI:MGI:87991"
     exon            1..144
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1892
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /note="albumin 1; serum albumin"
                     /codon_start=1
                     /product="albumin preproprotein"
                     /protein_id="NP_033784.2"
                     /db_xref="CCDS:CCDS19412.1"
                     /db_xref="GeneID:11657"
                     /db_xref="MGI:MGI:87991"
                     /translation="MKWVTFLLLLFVSGSAFSRGVFRREAHKSEIAHRYNDLGEQHFK
                     GLVLIAFSQYLQKCSYDEHAKLVQEVTDFAKTCVADESAANCDKSLHTLFGDKLCAIP
                     NLRENYGELADCCTKQEPERNECFLQHKDDNPSLPPFERPEAEAMCTSFKENPTTFMG
                     HYLHEVARRHPYFYAPELLYYAEQYNEILTQCCAEADKESCLTPKLDGVKEKALVSSV
                     RQRMKCSSMQKFGERAFKAWAVARLSQTFPNADFAEITKLATDLTKVNKECCHGDLLE
                     CADDRAELAKYMCENQATISSKLQTCCDKPLLKKAHCLSEVEHDTMPADLPAIAADFV
                     EDQEVCKNYAEAKDVFLGTFLYEYSRRHPDYSVSLLLRLAKKYEATLEKCCAEANPPA
                     CYGTVLAEFQPLVEEPKNLVKTNCDLYEKLGEYGFQNAILVRYTQKAPQVSTPTLVEA
                     ARNLGRVGTKCCTLPEDQRLPCVEDYLSAILNRVCLLHEKTPVSEHVTKCCSGSLVER
                     RPCFSALTVDETYVPKEFKAETFTFHSDICTLPEKEKQIKKQTALAELVKHKPKATAE
                     QLKTVMDDFAQFLDTCCKAADKDTCFSTEGPNLVTRCKDALA"
     exon            145..202
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            203..335
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            336..547
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            548..680
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            681..778
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            779..908
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1123
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1256
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..1354
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1493
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1717
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1850
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1918
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2061
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2040..2045
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /note="hexamer: AATAAA"
     polyA_site      2061
                     /gene="Alb"
                     /gene_synonym="Alb-1; Alb1; BCL001; BCL002; BPL001"
                     /note="major polyA site"
ORIGIN      
        1 atattagagc gagtctttct gcacacagat cacctttcct atcaacccca ctagcctctg
       61 gcaaaatgaa gtgggtaacc tttctcctcc tcctcttcgt ctccggctct gctttttcca
      121 ggggtgtgtt tcgccgagaa gcacacaaga gtgagatcgc ccatcggtat aatgatttgg
      181 gagaacaaca tttcaaaggc ctagtcctga ttgccttttc ccagtatctc cagaaatgct
      241 catacgatga gcatgccaaa ttagtgcagg aagtaacaga ctttgcaaag acgtgtgttg
      301 ccgatgagtc tgccgccaac tgtgacaaat cccttcacac tctttttgga gataagttgt
      361 gtgccattcc aaacctccgt gaaaactatg gtgaactggc tgactgctgt acaaaacaag
      421 agcccgaaag aaacgaatgt ttcctgcaac acaaagatga caaccccagc ctgccaccat
      481 ttgaaaggcc agaggctgag gccatgtgca cctcctttaa ggaaaaccca accaccttta
      541 tgggacacta tttgcatgaa gttgccagaa gacatcctta tttctatgcc ccagaacttc
      601 tttactatgc tgagcagtac aatgagattc tgacccagtg ttgtgcagag gctgacaagg
      661 aaagctgcct gaccccgaag cttgatggtg tgaaggagaa agcattggtc tcatctgtcc
      721 gtcagagaat gaagtgctcc agtatgcaga agtttggaga gagagctttt aaagcatggg
      781 cagtagctcg tctgagccag acattcccca atgctgactt tgcagaaatc accaaattgg
      841 caacagacct gaccaaagtc aacaaggagt gctgccatgg tgacctgctg gaatgcgcag
      901 atgacagggc ggaacttgcc aagtacatgt gtgaaaacca ggcgactatc tccagcaaac
      961 tgcagacttg ctgcgataaa ccactgttga agaaagccca ctgtcttagt gaggtggagc
     1021 atgacaccat gcctgctgat ctgcctgcca ttgctgctga ttttgttgag gaccaggaag
     1081 tgtgcaagaa ctatgctgag gccaaggatg tcttcctggg cacgttcttg tatgaatatt
     1141 caagaagaca ccctgattac tctgtatccc tgttgctgag acttgctaag aaatatgaag
     1201 ccactctgga aaagtgctgc gctgaagcca atcctcccgc atgctacggc acagtgcttg
     1261 ctgaatttca gcctcttgta gaagagccta agaacttggt caaaaccaac tgtgatcttt
     1321 acgagaagct tggagaatat ggattccaaa atgccattct agttcgctac acccagaaag
     1381 cacctcaggt gtcaacccca actctcgtgg aggctgcaag aaacctagga agagtgggca
     1441 ccaagtgttg tacacttcct gaagatcaga gactgccttg tgtggaagac tatctgtctg
     1501 caatcctgaa ccgtgtgtgt ctgctgcatg agaagacccc agtgagtgag catgttacca
     1561 agtgctgtag tggatccctg gtggaaaggc ggccatgctt ctctgctctg acagttgatg
     1621 aaacatatgt ccccaaagag tttaaagctg agaccttcac cttccactct gatatctgca
     1681 cacttccaga gaaggagaag cagattaaga aacaaacggc tcttgctgag ctggtgaagc
     1741 acaagcccaa ggctacagcg gagcaactga agactgtcat ggatgacttt gcacagttcc
     1801 tggatacatg ttgcaaggct gctgacaagg acacctgctt ctcgactgag ggtccaaacc
     1861 ttgtcactag atgcaaagac gccttagcct aaacacatca caaccacaac cttctcaggc
     1921 taccctgaga aaaaaagaca tgaagactca ggactcatct tttctgttgg tgtaaaatca
     1981 acaccctaag gaacacaaat ttctttaaac atttgacttc ttgtctctgt gctgcaatta
     2041 ataaaaaatg gaaagaatct aaaaaaaaaa aaaaaa
//
