LOCUS       NM_198111              10263 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus A kinase anchor protein 6 (Akap6), mRNA.
ACCESSION   NM_198111 XM_885325 XM_913082 XM_982248
VERSION     NM_198111.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10263)
  AUTHORS   Dias,A.P., Rehmani,T., Salih,M. and Tuana,B.
  TITLE     Tail-anchored membrane protein SLMAP3 is essential for targeting
            centrosomal proteins to the nuclear envelope in skeletal myogenesis
  JOURNAL   Open Biol 14 (10), 240094 (2024)
   PUBMED   39378988
REFERENCE   2  (bases 1 to 10263)
  AUTHORS   Martinez,E.C., Li,J., Ataam,J.A., Tokarski,K., Thakur,H.,
            Karakikes,I., Dodge-Kafka,K. and Kapiloff,M.S.
  TITLE     Targeting mAKAPbeta expression as a therapeutic approach for
            ischemic cardiomyopathy
  JOURNAL   Gene Ther 30 (7-8), 543-551 (2023)
   PUBMED   35102273
REFERENCE   3  (bases 1 to 10263)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10263)
  AUTHORS   Hakem Zadeh,F., Teng,A.C.T., Kuzmanov,U., Chambers,P.J.,
            Tupling,A.R. and Gramolini,A.O.
  TITLE     AKAP6 and phospholamban colocalize and interact in HEK-293T cells
            and primary murine cardiomyocytes
  JOURNAL   Physiol Rep 7 (14), e14144 (2019)
   PUBMED   31325238
  REMARK    GeneRIF: AKAP6 interacts with PLN in HEK-293T and murine
            cardiomyocytes.
REFERENCE   5  (bases 1 to 10263)
  AUTHORS   Ohlemiller,K.K., Kiener,A.L. and Gagnon,P.M.
  TITLE     QTL Mapping of Endocochlear Potential Differences between C57BL/6J
            and BALB/cJ mice
  JOURNAL   J Assoc Res Otolaryngol 17 (3), 173-194 (2016)
   PUBMED   26980469
REFERENCE   6  (bases 1 to 10263)
  AUTHORS   Kapiloff,M.S., Piggott,L.A., Sadana,R., Li,J., Heredia,L.A.,
            Henson,E., Efendiev,R. and Dessauer,C.W.
  TITLE     An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP
            levels in cardiac myocytes
  JOURNAL   J Biol Chem 284 (35), 23540-23546 (2009)
   PUBMED   19574217
  REMARK    GeneRIF: The association of AC5 with the AKAP6 complex is required
            for the regulation of cAMP second messenger controlling cardiac
            myocyte hypertrophy.
REFERENCE   7  (bases 1 to 10263)
  AUTHORS   Michel,J.J., Townley,I.K., Dodge-Kafka,K.L., Zhang,F.,
            Kapiloff,M.S. and Scott,J.D.
  TITLE     Spatial restriction of PDK1 activation cascades by anchoring to
            mAKAPalpha
  JOURNAL   Mol Cell 20 (5), 661-672 (2005)
   PUBMED   16337591
  REMARK    GeneRIF: two alternatively spliced forms of mAKAP are expressed:
            mAKAPalpha, the longer form, and mAKAPbeta. mAKAPalpha is
            preferentially expressed in brain
REFERENCE   8  (bases 1 to 10263)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   9  (bases 1 to 10263)
  AUTHORS   Kapiloff,M.S., Jackson,N. and Airhart,N.
  TITLE     mAKAP and the ryanodine receptor are part of a multi-component
            signaling complex on the cardiomyocyte nuclear envelope
  JOURNAL   J Cell Sci 114 (Pt 17), 3167-3176 (2001)
   PUBMED   11590243
REFERENCE   10 (bases 1 to 10263)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147248.1, BC057114.1, AK147371.1, AK129115.1 and CT030137.13.
            
            On or before Oct 25, 2006 this sequence version replaced
            XM_913082.2, XM_885325.2, XM_982248.1, NM_198111.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147248.1, AK147371.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1014              AK147248.1         2-1015
            1015-3670           BC057114.1         965-3620
            3671-6398           AK147371.1         3672-6399
            6399-8459           AK129115.1         1858-3918
            8460-10263          CT030137.13        171649-173452       c
FEATURES             Location/Qualifiers
     source          1..10263
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 22.18 cM"
     gene            1..10263
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /note="A kinase anchor protein 6"
                     /db_xref="GeneID:238161"
                     /db_xref="MGI:MGI:3050566"
     exon            1..60
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            61..424
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            425..676
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            677..2431
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            2432..2554
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            2555..2651
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2815
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..2964
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            2965..3085
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..3232
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            3233..3454
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            3455..3670
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            3671..7058
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     exon            7059..10263
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7977..7982
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /note="hexamer: AATAAA"
     polyA_site      8011
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /note="major polyA site"
     regulatory      10239..10244
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /note="hexamer: AATAAA"
     regulatory      10243..10248
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
                     /note="hexamer: AACAAG"
     polyA_site      10257
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
     polyA_site      10263
                     /gene="Akap6"
                     /gene_synonym="Akapalpha; Akapbeta; PRKA"
ORIGIN      
        1 agtattgcat cctacagatg tgctgtaaac atcaaaaggc gacgttggga gcaggagatg
       61 ctgttttgga aagaagtaag gcttagattt ctccatgtta accatgagtg tgaccctttc
      121 cccactgcgg tcccaggacc cagaccccat ggcgactgat gcctcgccca tggccatcaa
      181 catgacacct accgtggagc aggaggaagg agagggagaa gaggccgtga aggacgtggg
      241 tgctgagcag cagtatggaa agccacctcc actccacaca gcagccgact ggaagattgt
      301 cctgcactta cctgagattg agacctggct ccggatgacc tcagagaggg tccgtgacct
      361 aacctactcg gtccagcagg atgcagacag caagcatgtg gatgtgcatc tagttcagct
      421 aaaggatatt tgcgaggata tttccgacca cgtggagcag atccatgccc tccttgagac
      481 ggagttctcc ctgaagctgc tgtcctactc ggtcaatgtc atcgtagaca tccacgcagt
      541 gcagctgctc tggcaccagc tccgcgtatc cgtgctggtc ctccgggagc gcatcctaca
      601 aggtctgcag gacgccaatg gcaactacac caggcagact gacattctgc aagcattctc
      661 tgaagaaaca acagagggcc ggcttgactc cctcacagaa gtggacgact ctgggcagtt
      721 aactatcaaa tgctctcaga attatttgtc tctggattgt ggtattactg cctttgaact
      781 ttctgactac agtccaagtg aggatctgct tggtggcctg ggcgacatga ccactagcca
      841 ggccaaaact aaatcgtttg actcttggag ttacagcgag atggaaaagg aatttcccga
      901 gctcatccga agcgttgggc tgcttacagt ggccactgag cctgtccctt ccagctgtgg
      961 agcagccaat gaggactcat ctcaagtgat cctttcagag gaccacagag gtggacatga
     1021 ggaagatggc gctcttgaac ctggagagca gctgggctca acactggaga cgtcttcctt
     1081 aggggacaca ctgacaaacg ctgctgaaca ccctccggag acagcaaacc aagactctac
     1141 ttcctctccg cagcttggtg cgaaaaaatc ccagcctggt ccttgtgaaa tgatgactcc
     1201 caagagatcc atccgcgatt gctttaatta taacgaggac tctcccacgc agcccacatt
     1261 gcccaaaaga gggctatttc taaaagaaac tcttaagaac gagcggagag gcagtgatgg
     1321 gaaggggagg gtggttgacc tgaagcctga gctgagcaga agcaccccgt ccctggtgga
     1381 accccctgac agatcgaagc tctgcctagt gttgcagtct tcctacccca gcagcccttc
     1441 tgccgccagc cagtcctatg agtgtttgca caaggtgggg atcggcaatc ttgaaaacat
     1501 agtcagaagt cacattaaag aaatttcttc cagtttggga aggcttactg actgccataa
     1561 agagaaaccg cgactgaaaa agcctcacaa gaccttggcc gaggtgtccc tgtgcaaaat
     1621 acctaaacgg ggaactggtt caggaaagca atccgagaat accaggagct cagtcgtgcc
     1681 gaccatggtg tctcctggag ctccgaaagc cacggcgaga ccagcaacag attctgcgtc
     1741 tacaacctca ggtgacacgt gccatcagag aaatcggggt ggaaaattgc cagcgcagtc
     1801 gaaggcctcc agctcatccc cttgtagtca cagcagtgag tcctctcttg gctcagacaa
     1861 catcaaatcc ccacttcctc tcctttcaaa aagccaaaaa ggctccccac ccgctccatg
     1921 tcacgccaca cagaacggtc aggtggtgga ggcctggtac ggctctgatg aatacctagc
     1981 gctgccatct cacctcaaac aaacggaggt gttagctctg aaactggaga acctaaccaa
     2041 gcttctaccc cagaaaccca gaggagagac tatccaggat attgatgact gggaactgtc
     2101 tgagatgaat tcagactctg aaatctatcc aacgtaccat atcaagaaaa aacacacaag
     2161 gctaggcacc gtctctccga gctcatccag cgacatagcc tcatctctcg gggagagcat
     2221 tgaatctggg cccctgagtg acattctttc tgatgaggac ttatgtatgc ccctctccgg
     2281 catgaaaaag ttcactgatg agaaatcaga gagaccttca tcctctgaga agaatgagag
     2341 ccattctgct acaaaatcag ccttaattca gaaactaatg aaagatattc agcaccaaga
     2401 taactatgaa gccatctggg aaagaattga ggggtttgtg aacaagctgg acgaattcat
     2461 tcagtggcta aacgaagcca tggagaccac ggagaactgg actccgccta aagccgagac
     2521 cgacagcctc cggctgtacc tggagacaca cttgagcttt aagttgaacg tagacagtca
     2581 ctgtgccctc aaggaagccg tggaggaaga aggacaccaa cttcttgagc tcattgcgtc
     2641 tcacaaagca ggactgaagg acatgctgaa gatgattgca agtcaatgga aggagctgca
     2701 gaggcaaatc aaacggcaac acagctggat tctcagagcc ctggacacca tcaaagccga
     2761 gatactggct actgatgtgt ctgtggagga cgaggagggg acggggagcc ccaaggctga
     2821 ggctcagctc tgctacctgg aagctcagag agacgctgtg gagcagatgt ccctcaagct
     2881 gtacagcgag cagtatacca gtggtagcaa gaggaaagaa gagtttgccg acatgtcgaa
     2941 agcgcattcg gtgggaagca atgggcttct ggactttgat tcagaatatc aggagctctg
     3001 ggattggctg attgacatgg agtcccttgt gatggacagc cacgacctga tgatgtcaga
     3061 ggagcagcag cagcatcttt acaagcgcta cagcgtggaa atgtccatca ggcacctgaa
     3121 aaagacagag ctacttagca aggttgaagc tttgaagaaa ggtggccttt cactaccaaa
     3181 tgatatcctg gaaaaagtgg attcaattaa tgaaaaatgg gagctgcttg ggaaaaccct
     3241 aagagagaag atacaggaca caatggcagg ccacagtggg tcgggcccac gtgacctgct
     3301 ctctcctgaa agcggaagcc tggtaaggca gctggaggtc aggatcaaag agctgaaaag
     3361 gtggctaaga gatacagagc ttttcatctt caattcctgt ctgagacaag agaaggaagg
     3421 aacgagcgcc gagaaacaac tccaatactt taagtcgctc tgtcatgaga tcaagcagcg
     3481 gcgtagagga gtggcctcca ttctgaggtt gtgccagcac cttctggatg accgggacac
     3541 ttgtaatctg aacgcagatc accagcccat gcagctgatc attgtaaacc ttgaaagaag
     3601 gtgggaagcc atcgtcatgc aagctgtcca gtggcaaaca cggttacgaa agaagatggg
     3661 aaaagaatct gagactctga atgtgattga ccctggcttg atggacctga atggaatgag
     3721 tgaggatgcc ctggaatggg atgagacaga cataagtaac aaactcatta gtgtgcatga
     3781 agaatccaac gaccttgatc aagacctgga gcctatggtc ccaacagtga aacttgaaga
     3841 gacacaccac aaggactccg gttatgaaga ggaggcaggt gactgtggag ggtcccagta
     3901 tacctcaaat atcactgccc cttccagccc acacatttac caagtgtaca gtctccacaa
     3961 tgttgagttc cacgaggaca gccacactca gtttctaaaa agcagcccca agttcacagg
     4021 cacagtgcag cccactgttt taactaagag cctcagtaaa gattcttcat tttcatccac
     4081 aaaatcgtta ccagaccttt tagggggttc cagcttggtg aggccttact cgtgtcagag
     4141 tggagacttg agccagaatt caggcagtga gagtggaatt gtcagcgaag gagacaatga
     4201 gatgccaacc aactccgaca tgagcttgtt cagtatggtc gatgggtccc cgagtaaccc
     4261 tgaaacacaa catctggacc cacaaatggg agacgcagcc aatgtgctgg agcaaaaatt
     4321 taaagatgag ggggagtgca ttaagctttc aagtgtctct caggcatctg tctcaccagt
     4381 gggttgtgta aatgggaaag ctggggactt aaacagtatt accaaacaca ccactgattg
     4441 tttgggagac gaattacaag gaaaacatga ggtgtttaca ttttatgact actcgtacct
     4501 ccaaggctca aaactcaaat tcccaatgat aatgaaacag ccgcagagtg agaaggcaca
     4561 tttggaggat ccccttcttc gtggtttcta ttttgataaa aagtcctgca aacctaaaca
     4621 tcagacttct gagtcacaac cagacgcgcc cctccatgaa aagatcttgg caagtgcccc
     4681 ccacgagatg ggtcgaagct catacaaaag tagcgacata gagaaggcac tcacgggcat
     4741 ccagaatgcc cgacagctct cccttttatc tcgtagctca tctgtagagt ccctttcccc
     4801 agggggtgat ttgtttggat tgggaatctt taaaaatggc agtgacagcc tccagcgaag
     4861 cacttcttta gaaagttggt tgacatccta taagagcaac gaggatcttt ttagctgtca
     4921 cagctctggg gacataagtg tgagcagtgg ctcggttggt gagctgagca agaggacatt
     4981 agatcttttg aatcgtctgg agaacataca gagcccctca gagcaaaaga tcaagcggag
     5041 tgtttcagat atcactctgc aaagcagttc ccaaaagatg tccttcagtg gccagatgtc
     5101 actggatgtc gcatcctcta tcaatgaaga ctcgccggca tctcttaccg aactgagtag
     5161 cagcgatgag ctctctcttt gctcggagga cattgtgtta cacaaaaaca aggtcccaga
     5221 gtccaacgca tcattcagga agcgcctgaa tcgctcggtg gctgatgaga gcgacgtcaa
     5281 tgtcagcatg attgtcaacg tctcctgcac ctctgcttgc actgatgacg aagacgacag
     5341 cgacctcctc tccagctcca ctctcacctt gacggaagaa gagctgtgtc tcaaagatga
     5401 ggatgacgac tccagtatcg caacggatga tgaaatttat gaggaaagca acctgatgtc
     5461 tgggctggac tacatcaaga acgaactgca gacgtggata agacccaaac tttccttgtc
     5521 gagagaaaag aaacggccca gtgtcactga tgaaataaag gtcaataaag atggaggaag
     5581 taccgagagg gccaatccct cggacaccct ggacattgag gcccttctaa attgctccat
     5641 aaaacgtctc tctgaaaaca atgggaatgg caagaaccca cccagaactc atgacttagg
     5701 aaccaaaggt gaaaataaga aaaatacgta cgacgttact aaagatccac atgtggccga
     5761 catggaaaat ggcaatgttg aaagtactcc agagagagaa aaggagaagc cagagatccc
     5821 agaggcatca gcgaaccttg cttcaaatgt gaaaaagatt tctgaatcca agcacgacga
     5881 gtatgaagca ttaatggatg gttctgatga ttcaagtgtc actgggaagg aatttggtcc
     5941 cccaaatgat aggcatcctc cacagattgg tgccgatccc cagcatcctg aaaggggtga
     6001 ctgcacatca gtccagaact cttgctcagg actactgttg gaaaccggtg gcggaagcag
     6061 acaagatagt gatggactca aatctttgtc taatgatgca ccaagtgtgg ctagaaacgc
     6121 tgctggttgc tgcctactcg aacaaaatga gacagaggaa agtgcttcta tcagcagcag
     6181 cacttcctgt tgcaactgca agccagatgt tttccatcag aaagatgatg aagattgttc
     6241 ggtacatgac tttgttaagg aaatcattga catggcatca acagccctca aaagtaaatc
     6301 acaacctgag agtgaggtgg ccgctcccac gtcactgacc caaattaagg agaaagtgtt
     6361 agagcattcg catcggccca tacacctgag gaagggagat ttttactcct acctatctct
     6421 ttcgtcccat gacagtgact gtggggaggt caccaattac atagatgaga agagcaacac
     6481 cccattgcca ccagacaccg tggactctgg cttagatgac aaggaagacg tggactgctt
     6541 ctttgaagct tgtgttgagg acgagcctgc tgatgaggaa gcccgtctct ccagtgccct
     6601 tccaaatgaa tcagaagtcc aggatgaagc tgctaagcca gaacaaatga cagccagctc
     6661 ttctgtgttc cgtgatgaga cagacacggt gcctctttca ggactttccc ctcagaaggg
     6721 agctgatgat gcaaaggaag gagatggtgc gtcccacact tcccagggct gtgtggagag
     6781 cgcagagcct accacccccc caggaaaggc caagagagag gggagttcaa gaaagcaaag
     6841 tgtatcagga acgccagaag aaaacgctgc ttcagccaaa ccgaaaattc aagctttctc
     6901 tttgaatgca aaacagccaa aaggcaaggc tgcactgtat cccagccccc aaactttaac
     6961 ctgcaaagag aagctcgtaa gctttcatga agatcgacat agtaacatgc ataggtagaa
     7021 tgtaatgccc ccaagcatgg aactcatctc attgaaagat agcctggctg aagctcgggg
     7081 ctggcctgac ccaccctggg ctggtcttgg gttccatcct gttatcatca ctgcctcctg
     7141 ccacgttgac ttcctgaaga cgaaccttcc ttctgaatgc ggtctgtcca cgtgggcctc
     7201 ccgatatgga tgtgtgcatt gctcctctta ggtgatcgtc ttagttcctc aaagctgctt
     7261 gttctcccgt ggattcctgt cccaagctac ctctggcaac cctctctcca gcaagacttc
     7321 tattttccct ctctcctccc tcctcctttt aaagctctgc agttcaccaa attgatggtc
     7381 cattaaaccc actgtctgga atgacacccc tcccatcggt acttgaccaa ttttatgttt
     7441 tgctctgaaa tttttcatga tattatgcct atgtttattg aaagagattt acctaaaaag
     7501 ccatcccttg atttgattgt agtatagaag agacacattg atccttatga caaaattaag
     7561 tgatgttttg aaagtgccat tttaattatt tctttttaat aataatctat gcagcacttc
     7621 aagaaacaac tataacagtg ttgtataaac tggtacattc tactattaag tttgtttttg
     7681 gtttctatgc ttcttgaggt ggtaatgaga aaaatgtttg tttttttttt taaacggtgt
     7741 gccttgctgt atttcttata ccatttatta aaaagctgct tttgtggtaa tattatgttg
     7801 gtttgaaagg aggaaatagc aaggttaaga tgcgtgaata atttctgtat atatgtataa
     7861 gctaatacaa acactgatgt atgacagtat aaaatgcttt catgtttgtg atgtccagtg
     7921 atgtggagaa tataagcctt aaacccgttc gattgcatgg taattaaaat tggcataata
     7981 aaaatagctt attgggggaa aggaaaatta atgatctctt ctacctgtgt tctttaccaa
     8041 attcttgcat ctggttctag aaaagaaaaa agaatcaaac tccatatatt agcttccaaa
     8101 atatccatat tgcacagaag gcttacattg cttagactac agactaggcc tgaagccttc
     8161 ataattttca aaaatctttc tgtttcacta taaacatcct gaaatagcaa aggtttaaag
     8221 gccatttcca tcaacaatgt tttattctaa atgtttttat ttctacttgc taatggttta
     8281 ataatagttg tatttggaga tctcttacat gacctaattt attttaaata tttgaatggt
     8341 tttggtggat ggtatagaaa atttgattat tattttattt aaactataga tttcaggtat
     8401 atttattttg ttaagaaaaa tcaacagagg aatattccat ttggtctttt tttttttttg
     8461 acttgaagaa ttcagctttt aatttatatc ataactccta ctaaagtgcc tgacacacag
     8521 taggtatttc atagagtttc ctgaatttga gtattgagtg gggttttaca tatatatatt
     8581 tatatatgtt tcctgcatta aaactagaaa aagacgtgca aagtgaagca catctataat
     8641 cacacattta taatcagatt tccaaaagcc aatagaacat gacagacata tgtagccacc
     8701 gaaatgacaa tcattcattc aatagattac tcattagcat cttttgcctg caagtcacta
     8761 ttctatattc agggagagca gctatgaacg atgcactgcc tttggaggtt tatctatgtt
     8821 tgagacagag tgactgacca cacagacgtg tgtgccataa cgtcccacag atgaggaaga
     8881 aagcaagtgt agagaaagag tcacaacgag agagacagcg gtgagaggct ggggcaaaga
     8941 gaaaggctat gggagaagag gggttagcag ggcttcacta catgtgtgaa aagagagaaa
     9001 gccaaataga gagacctgca agatgtttac agagctgaca tggagcgttt gtgtgctgtg
     9061 tagtaggtat aggagaccca gtagcttgtg cggggcttta ttttatccca caattggaac
     9121 tttactggcg tcctcccagg aacacttaaa taattttgcg tggattttgc cccttctaat
     9181 ctttgctgca catattttta aatggatggc tcattctagg cttttgggta tgtagtgact
     9241 tcttccaacg gagtcttaga gagacatcta gttatagtgt ttatgaggat cacaaagggg
     9301 agatgttaga cataactatg ttgtaggggg aaagaaaggg gaaattagct agatttaagg
     9361 caatgacaga gtgcacaggg atcgtagcct gaaatacaga gaaagacaga tcttagagcc
     9421 ctgaaaagta tttgaacatt tttggacctc tgttaggata tggcattatt ttatatactg
     9481 agacaacctg aatttctctt agtaagtaat gtcaagtcta agtctattga aaagacattc
     9541 aaaaaattaa tggaccatgc tggactattt gcctcttttg tactcatgaa gacttagaat
     9601 ttgaaaatat ttattagtta tctgcttaac actaacacca agttgatcag gttgactctt
     9661 gagtttattg atgccttttc cagccagaag agatggaaga gcctcagtct cataccctgt
     9721 gtagacacta acttcccatc tgcatttgaa aacagctcat ttggtttgta ttgatttgat
     9781 caacactatc tacgcatgtc ccatgacaat tgtttgttat ttgttaaggc aaagtatccc
     9841 tcttatgggc atgtgtttct gttagaatgt gctctcttag gttgctaaat aaagtccaca
     9901 gggtacccct ccccttttag tttggtgtat tggtcctatg cctgtgctgc agagaggccc
     9961 ttagaagatt cctggtccct ctgtctcatg gccgcccttc aggtaattga gaacagttac
    10021 tctctttcac aggcagttcc tccaactgcc cttcatatat catgacttca gatccatttc
    10081 aacctgactg aatgttaaac aggcagaacc cttgatgtca agggactgtc ttcatcctac
    10141 atgtagagag gtgtgtggac acttaagtga taagttttct caaaaatata ttcaagatat
    10201 atgtttattc tactattgta aatttcaata aataaacaaa taaacaagtg aataaaataa
    10261 gaa
//
