LOCUS       NM_021299               2826 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus adenylate kinase 3 (Ak3), transcript variant 1, mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_021299
VERSION     NM_021299.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2826)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2826)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2826)
  AUTHORS   Noma,T., Fujisawa,K., Yamashiro,Y., Shinohara,M., Nakazawa,A.,
            Gondo,T., Ishihara,T. and Yoshinobu,K.
  TITLE     Structure and expression of human mitochondrial adenylate kinase
            targeted to the mitochondrial matrix
  JOURNAL   Biochem J 358 (Pt 1), 225-232 (2001)
   PUBMED   11485571
REFERENCE   4  (bases 1 to 2826)
  AUTHORS   Bonhomme,F., Catalan,J., Britton-Davidian,J., Chapman,V.M.,
            Moriwaki,K., Nevo,E. and Thaler,L.
  TITLE     Biochemical diversity and evolution in the genus Mus
  JOURNAL   Biochem Genet 22 (3-4), 275-303 (1984)
   PUBMED   6375655
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147060.1 and AW457236.1.
            
            On Jul 24, 2018 this sequence version replaced NM_021299.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058191.1, AK147060.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2809              AK147060.1         2-2810
            2810-2826           AW457236.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..2826
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 23.61 cM"
     gene            1..2826
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /note="adenylate kinase 3"
                     /db_xref="GeneID:56248"
                     /db_xref="MGI:MGI:1860835"
     exon            1..283
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /inference="alignment:Splign:2.1.0"
     exon            284..403
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /inference="alignment:Splign:2.1.0"
     exon            404..576
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /inference="alignment:Splign:2.1.0"
     exon            577..695
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /inference="alignment:Splign:2.1.0"
     exon            696..2810
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2789..2794
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /note="hexamer: AATAAA"
     polyA_site      2810
                     /gene="Ak3"
                     /gene_synonym="AK-3; Ak3l; Ak3l1; Akl3l"
                     /note="major polyA site"
ORIGIN      
        1 acttccggga gagccgggcg tcctggccac cgcccgcttg cagctgccag ccctccaggg
       61 ccgcggagcc tgtgagcgcg caggccaggc cacagaccag cgtctgcgca gctcggacca
      121 ccgccagcca ccatgggggc gtcggggcgg ctgctgcgcg ccgtgatcat gggggccccg
      181 ggctccggca agggcaccgt gtcgtcacgc atcaccaaac acttcgagct gaagcacctc
      241 tccagcgggg acctgctccg ccagaacatg ctgcagggca cagaaatcgg tgtgttggcc
      301 aagactttca ttgaccaagg aaagctgatc ccagatgacg tcatgactcg gctggccctt
      361 cacgagctca aaacccttac ccagtgtagc tggctgttgg atggatttcc aaggacactt
      421 ccacaggcag aagccctgga taaagtttat cagatagaca cagtgataaa tctcaacgtg
      481 ccctttgagg tcattaaaca gcgccttact gctcgctgga tacatcctgc cagtggtcga
      541 gtatacaaca ttgaattcaa ccctcccaag actgtgggca ttgatgacct gaccggagaa
      601 cctctgattc agcgcgagga tgacaaacca gagacagtga tcaagagact aaaggcctat
      661 gaagcccaga cagagccggt cctgcagtat taccagaaaa aaggggtgtt ggaaacattc
      721 tctggaacag aaaccaacaa gatctggccc cacgtatact ccttcctaca gacgaaagtt
      781 ccagaaacta cccaaaaggc ctctgttact ccctgaagag ggcagcaact ggcaggatga
      841 ggcagggcct cctctcctct tcttgcctct gtatctcaaa gctcttttcc taagacttct
      901 ctaaaaatta tgatttattc ctaatggcta agccaaatga gtcagatact tagcctgatc
      961 tgttaaaata gcctcacatg tttaatctag gacctggttg tcttctgtgg acgtgcaatt
     1021 ggaaaacgtc agagatgttg aaacaaacta actcggagag caactggtga ccatctaacc
     1081 ttctgttcag ttagtcaaag tggttgatca cattttcatg tttttctgga aaagttcaaa
     1141 aaaaatttac cattcaaggc agataaataa tctcattcga ggcttttcaa taagccaatg
     1201 cccactgcaa ttcaggaaga tgttttctgg cctgaaggga tgtggtatta gaagacactg
     1261 tctatagatt tcagaaagca agcaacaggc tttacagatg ttaaatgtaa actcactgct
     1321 accttaacag gaaaagccaa gggaacaggc caccatgctg tgtgtcctct acttatccaa
     1381 tctgctgtga aaatgcagcc actggcacgt agggacgtgt gacttggata tggaccaagg
     1441 tgtatgactt aggttctgac tgaagttcta ggagcagcac tggcactgac aatggcatta
     1501 agtcctaagt tctcccgtgt cactcagggt gaggaccaag ttttaggacc tacccgtttg
     1561 tttccctctt tgatccaagc ggactgcctg ccttgatgag caagacagta aacagaaaac
     1621 taaagggtga caccacaccc atgggaattt gccactctgc aagtagacgg gacatgctgg
     1681 ggacagcccc ccagcagaaa gactgactaa ttccactaca caacaggtgt agtaatagga
     1741 ttttgcatgg tgggttcaaa agcactgtaa gggagttccc ttaagaacat tatacctgtg
     1801 ttgaagttct aaattaaaga tcctcttgtc tcggcctctc tcaagtgctg ggatcactgt
     1861 gtgctaccac ttcccaccct aatttaaagg gaagcaattc ttctggtacc atctaagcag
     1921 cctcctcttc tacttacagc agtgggatcc aaccagcctg agtgctgggc aggcatccta
     1981 tactgtggtt tatcttcagc cccttctgtt gctgatgctg gtggtggtgg ctcagttctg
     2041 ttgctctgac aggatctcac tgtagttgac tgccctgaac tctgtagtca ggctggcttc
     2101 aaactcagag ccatcacctg tttctgcctc ccaagtgctg aagttaaagg tgcgcaccac
     2161 caccacactc aggctggctt tggattatta tatagtccaa actggcctca cattcaatcc
     2221 tcttggttta gtctcctgag tgcttaaatt acaggtgtgt accactaaac caaccctaag
     2281 aatccatttt aaaatgtcag tcactttaga tttcttagtg gggcaaggac ctgcccttac
     2341 atattgtggc ctgaagggac aaaatatgag aagttcaatg aaaagataat tccccctttc
     2401 aggaaagatg ttctcttatt ttacttggtg ctaaatcaaa gaatcaagcc tttgttcaag
     2461 cctttgcaat tttggcctat tttatttcag agagcaaatg gttgttatat atttgggagt
     2521 gggaaggaat ctttgatttt taaatttcac tgttgatctt tcaaatagac taggccttag
     2581 gattacaatg aacaactttg tcctttgtca acgtttctct actgccttat ttggatgttg
     2641 ataaccactt cctacaacct gttgtgaatt acctaaagct aggactgatc tgcaggtgat
     2701 ctcagcactg tggctgttgc cctttgcccc tggcccttca caaaccccca tcctgtctgc
     2761 tgccacaatg tctcacaggc ttctttctaa taaatggtct tcaaacagta aaaaaaaaaa
     2821 aaaaaa
//
