LOCUS       NM_026203               4885 bp    mRNA    linear   ROD 06-FEB-2024
DEFINITION  Mus musculus Abelson helper integration site 1 (Ahi1), transcript
            variant 1, mRNA.
ACCESSION   NM_026203
VERSION     NM_026203.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4885)
  AUTHORS   Kong,A., Liu,T., Deng,S., Xu,S., Luo,Y., Li,J., Du,Z., Wang,L.,
            Xu,X. and Fan,X.
  TITLE     Novel antidepressant-like properties of the fullerenol in an
            LPS-induced depressive mouse model
  JOURNAL   Int Immunopharmacol 116, 109792 (2023)
   PUBMED   36738679
REFERENCE   2  (bases 1 to 4885)
  AUTHORS   Wang,B., Shi,H., Yang,B., Miao,Z., Sun,M., Yang,H. and Xu,X.
  TITLE     The mitochondrial Ahi1/GR participates the regulation on mtDNA copy
            numbers and brain ATP levels and modulates depressive behaviors in
            mice
  JOURNAL   Cell Commun Signal 21 (1), 21 (2023)
   PUBMED   36691038
  REMARK    GeneRIF: The mitochondrial Ahi1/GR participates the regulation on
            mtDNA copy numbers and brain ATP levels and modulates depressive
            behaviors in mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4885)
  AUTHORS   Wang,B., Shi,H., Ren,L., Miao,Z., Wan,B., Yang,H., Fan,X.,
            Gustafsson,J.A., Sun,M. and Xu,X.
  TITLE     Ahi1 regulates serotonin production by the GR/ERbeta/TPH2 pathway
            involving sexual differences in depressive behaviors
  JOURNAL   Cell Commun Signal 20 (1), 74 (2022)
   PUBMED   35643536
  REMARK    GeneRIF: Ahi1 regulates serotonin production by the GR/ERbeta/TPH2
            pathway involving sexual differences in depressive behaviors.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4885)
  AUTHORS   Zhang,Q., Hu,Q., Wang,J., Miao,Z., Li,Z., Zhao,Y., Wan,B.,
            Allen,E.G., Sun,M., Jin,P. and Xu,X.
  TITLE     Stress modulates Ahi1-dependent nuclear localization of ten-eleven
            translocation protein 2
  JOURNAL   Hum Mol Genet 30 (22), 2149-2160 (2021)
   PUBMED   34218273
  REMARK    GeneRIF: Stress modulates Ahi1-dependent nuclear localization of
            ten-eleven translocation protein 2.
REFERENCE   5  (bases 1 to 4885)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4885)
  AUTHORS   Barr,N.I., Stewart,M., Tsatsanis,C., Fulton,R., Hu,M., Tsujimoto,H.
            and Neil,J.C.
  TITLE     The fit-1 common integration locus in human and mouse is closely
            linked to MYB
  JOURNAL   Mamm Genome 10 (6), 556-559 (1999)
   PUBMED   10341084
REFERENCE   7  (bases 1 to 4885)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
REFERENCE   8  (bases 1 to 4885)
  AUTHORS   Jiang,X., Villeneuve,L., Turmel,C., Kozak,C.A. and Jolicoeur,P.
  TITLE     The Myb and Ahi-1 genes are physically very closely linked on mouse
            chromosome 10
  JOURNAL   Mamm Genome 5 (3), 142-148 (1994)
   PUBMED   7911043
REFERENCE   9  (bases 1 to 4885)
  AUTHORS   Justice,M.J., Siracusa,L.D., Gilbert,D.J., Heisterkamp,N.,
            Groffen,J., Chada,K., Silan,C.M., Copeland,N.G. and Jenkins,N.A.
  TITLE     A genetic linkage map of mouse chromosome 10: localization of
            eighteen molecular markers using a single interspecific backcross
  JOURNAL   Genetics 125 (4), 855-866 (1990)
   PUBMED   1975791
REFERENCE   10 (bases 1 to 4885)
  AUTHORS   Poirier,Y., Kozak,C. and Jolicoeur,P.
  TITLE     Identification of a common helper provirus integration site in
            Abelson murine leukemia virus-induced lymphoma DNA
  JOURNAL   J Virol 62 (11), 3985-3992 (1988)
   PUBMED   2845118
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK080373.1, AK036336.1 and BC065146.1.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by NM_026203.4.
            
            On Nov 18, 2010 this sequence version replaced NM_026203.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065146.1, SRR1660815.53816.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               AK080373.1         1-112
            113-3643            AK036336.1         3-3533
            3644-4885           BC065146.1         3539-4780
FEATURES             Location/Qualifiers
     source          1..4885
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 9.75 cM"
     gene            1..4885
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /note="Abelson helper integration site 1"
                     /db_xref="GeneID:52906"
                     /db_xref="MGI:MGI:87971"
     exon            1..206
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            207..675
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     CDS             365..3508
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /note="isoform 1 is encoded by transcript variant 1;
                     jouberin; abelson helper integration site 1 protein"
                     /codon_start=1
                     /product="jouberin isoform 1"
                     /protein_id="NP_080479.2"
                     /db_xref="CCDS:CCDS35860.1"
                     /db_xref="GeneID:52906"
                     /db_xref="MGI:MGI:87971"
                     /translation="MEPETPEKVDSAQEKVRGKTPTADDSDDSREKTGIEEKGELTDA
                     YQLQVAEEMAKEIKKKIRKKLKEQLTYFPPDTLLHDDKLASEKRKKKKKKVPVPTKPE
                     SSPSDVCDSAVEGEQKKEGTPEDSQHMEGICSREQDVDATVPENAKPKPKKTKKKTKA
                     VSNDNEDTNGDGVHEITSRDSPVHPKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKI
                     HVVDEHTGQYVKKDDSERPVSSYYEKDNVDYILPIMTQPYDFKKLKSRLPEWEEQVIF
                     NENFPYLLREFEECPKVILFFEILDFLSMDEIKNNSEVQNQECGFRKIAWAFLKLLGA
                     NGNANINSKLRLQLYYPPTKPRSQLNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDC
                     IKPSYRSMMALQEERGTPVYCERHRETSSVDTEPGLEDSKEEVKWKRLPGQACRIPNK
                     HLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIY
                     DLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTG
                     CYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDTY
                     VKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDLRIL
                     AARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSDLPFKSTI
                     RDISYHPLENMVAFCAFGQSEPILLYIYDFQVAQQEAEMLKRYSGTLPLPGIHQSEDA
                     LCTCPKLPQQGSFQIDEFVNTENSSSRKIQLVKQRLETVTEVIRSCAAKVNKNLSMTS
                     PPPGPAKKPRVKQSFVLTTDEIIHQFGLPQTAFISIERGPFVRHVDPPPMVVALYDYT
                     ASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHVASETLYRDSPPKVKE
                     RSPPLTPKEKTKPEKPLASQKQSLSKGRPLDPRLGPQPVGHSEKGKDQNVEDRGHKVD
                     METKKSEPVVRKVTLIE"
     exon            676..845
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1065
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1258
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1354
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1540
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1693
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1826
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..1950
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            1951..2180
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2181..2287
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2288..2406
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2407..2537
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2678
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2679..2878
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2879..2905
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..3026
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            3027..3082
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            3083..3245
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3343
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            3344..3402
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            3403..3505
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
     exon            3506..4851
                     /gene="Ahi1"
                     /gene_synonym="1700015F03Rik; Ahi-1; D10Bwg0629e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatctcccgt ccctagtctg agttacctag gcaacagcgg cagaggcggg cctgacgtca
       61 cgggcggcgc gcctccgcac tgcggcactg agctggctgg acagcgcgcg tcgccagcgg
      121 tcctgccggc caagctgccg cctccctcgt cctcgcctag gcgcagggaa ccgcttcgcg
      181 ccgccgccgg gctgtccctc ctctctcctg ttaccctcaa agtaaccttc tggctacctt
      241 agaactaaaa ttggcactaa aagcctagag aagtgagcag cacgtgaaga ttcagaggac
      301 aatgttagtg tagagccata caaacaagaa aagacaagta aacactaccc agatcgcaca
      361 ggaaatggag ccagaaactc cagagaaggt ggattctgca caagagaaag tcagaggcaa
      421 gaccccgaca gcagatgatt cagatgacag ccgagaaaag actggcatag aagagaaagg
      481 agaactgacc gacgcctatc agctgcaggt agctgaagaa atggcaaagg agatcaagaa
      541 gaaaataaga aagaagctaa aggaacagct gacctacttt cctccagaca ctctattgca
      601 tgacgacaag ctggccagtg aaaaaagaaa gaagaagaag aagaaagtgc cagtgcccac
      661 taagcctgag tcaagtccct cagatgtctg tgacagtgca gttgaagggg aacaaaagaa
      721 agaaggtacc cctgaggact ctcagcacat ggagggaatc tgctcgagag agcaggatgt
      781 ggatgccact gtgccagaga acgcaaagcc caaacccaag aagacaaaga agaagactaa
      841 agcagtttca aatgataatg aagacactaa tggagatggt gttcatgaga taacaagccg
      901 agacagccca gttcatccca agtgcttgct ggatgatgac ctcgtcatgg gagtctacat
      961 tcaccgaacc gatagactta aatctgactt tatgatttct cacccaatgg taaagatcca
     1021 tgtggttgat gagcacactg gccagtacgt caagaaagat gacagtgaac gtcctgtttc
     1081 atcttattat gagaaagaca acgtggacta tattctccct attatgacac agccatatga
     1141 ctttaaaaag ctaaagtcaa ggcttccgga gtgggaggag caagttattt ttaatgaaaa
     1201 ttttccctat ttgcttcgag agtttgaaga atgtccaaaa gtcatcctgt tctttgagat
     1261 tcttgacttt ttaagcatgg atgaaatcaa gaataactct gaggttcaaa accaagagtg
     1321 tggctttcgg aaaattgcct gggcgtttct taagcttctg ggagccaatg ggaatgcaaa
     1381 catcaactca aaacttcgcc tgcagctcta ctacccaccg actaagcctc gatcccagct
     1441 aaatgtcgtc gaggtttttg aatggtggtc caagtgtcca agaaatcgtt atccatcaac
     1501 attgtatgta accgtacgag gattgaaagt cccggactgt ataaagccat cttaccgctc
     1561 tatgatggct ctccaggagg aaaggggtac accagtgtac tgtgaacgtc accgtgaaac
     1621 aagttccgtg gacacagaac ctggactaga agattcaaag gaggaagtga agtggaaacg
     1681 tctgcctggc caggcctgtc gtatcccaaa caagcatctc ttctcactga atgctggaga
     1741 acgcggctgt ttctgtcttg atttctctca caatggaagg atattagcag cagcctgtgc
     1801 cagccgagac ggatatccga ttatattata tgaaattcct tctggacgtt ttatgagaga
     1861 attgtgtggc cacctcaata tcatttatga tctcgactgg tcaaaagacg atcgctatct
     1921 cgttacttca tcctctgacg gcactgccag agtttggaag aatgaaatca atagcacgag
     1981 cacgttcaga gtcttacctc acccctcctt cgtctacacg gctaaattcc acccagccac
     2041 acgggagctg gtggttacag gatgctacga ctctatgata aggatttgga aaattgatgc
     2101 aagggaggat gctgccatat tagtgcgcca gttggatgtg cacaagagct ttgtcaactc
     2161 catctgtttt gacgatgaag gtcaccacat gtactcagga gactgcatcg gggtcatcgt
     2221 tgtctgggac acgtacgtca aagtgaatga tgtgcaacac tccgtgcgcc actggacgat
     2281 aaataaggaa attaaggaaa ctgaattcag gggagttcca ataagttacc tggaggttca
     2341 tcccaatgga aagcgtttgc taatccacac caaagacagt actctgagga ttatggacct
     2401 gcggatattg gcagccagga aatttgtggg tgcagcaaat taccgtgaga agatccatag
     2461 caccttgacg ccgtgcggga ctctgctctt ttctgggagt gaggatggga tagtatacgt
     2521 ttggaaccca gagacaggag aacaagtggc aatgtactct gacctgccat tcaagtccac
     2581 aatccgagac atctcttacc accccctgga gaatatggtt gccttctgtg cctttggaca
     2641 gagcgagccg attcttcttt atatttatga tttccaggta gcccagcagg aggctgaaat
     2701 gttgaaacgc tatagtggga cactcccgtt gcctgggata catcagagtg aggatgcttt
     2761 atgcacctgc cctaagctgc cccagcaggg ctcttttcag attgatgaat ttgtcaacac
     2821 tgaaaatagt tcatcaagaa agattcaact tgtgaaacag agactcgaaa ctgtcacaga
     2881 ggtgatacga tcctgtgctg caaaagtcaa caaaaatctc tcaatgactt cgccaccacc
     2941 aggccctgca aagaagccca gggtaaagca gtcgttcgtg ctgaccactg atgagatcat
     3001 acatcagttt ggactccccc agactgcatt tatcagcata gagagagggc cttttgtgcg
     3061 ccatgttgat ccaccaccaa tggtagtggc tctttatgac tacacagcca gccgatcaga
     3121 tgaactaacc atccatcgtg gagacattat ccgagtgtat ttcaaagata atgaagactg
     3181 gtggtacggc agcgtaagaa aggggcagga agggttcttt ccagctaatc atgtggccag
     3241 tgaaacactg tatcgagact cccctccgaa ggtaaaggag cgctcccctc ctttaactcc
     3301 caaggagaaa actaaaccag aaaagcctct ggcttctcaa aagcagtcgc tcagtaaggg
     3361 cagacccctg gatcccagac tgggcccgca gcctgtgggg cattctgaga agggcaaaga
     3421 tcaaaacgtg gaggaccgag gacacaaagt agatatggag acaaagaaaa gcgagccggt
     3481 ggtccgcaaa gtcaccctga tagagtaaaa agctggagac gaagcagaag ccgcctgatg
     3541 agtgcacatg atgtgacgtc cacgccagac ggagttctcg ttagattttg ggtgaaaaga
     3601 agcagtattt attgacctta aaaatctgaa gcaaacttag ctctaaaaag aaaaaaatca
     3661 ctgtggcctt tgggcttaat tgttatgaac cattgtgagt gttactggtc aaagtattgt
     3721 gcttgtgcta ttagtaacta catcagaatt atattgctgc tgctggaaaa gccaatagag
     3781 aaaaccccag aactgctact cagtaaatgt gaataacagt gtgcgcagtg ttagtcattc
     3841 actaagccat catcccgtgt acttgtggcc atgatgtggc tgtgccgtag gccgtcatcc
     3901 cgtgtacttg tggccatgat gcagatgctc tgcttttgaa gttagccgcg tgtaaaacct
     3961 aagtagctgc tggatattgt gtcttcaaac agccccagta acaaacgcgg tagaaacgac
     4021 agtttgcttt tgagaactaa atgtttgtgt ttcccttgag tgaatgtatg tcactcaaca
     4081 ctcctagact aagaatgatt ttggctggac tgacaacagt acaccaaatt tatttttatt
     4141 ttttagacag agtttatatt taacagcata agtaatttat ggatgtaaac tctgtagtgg
     4201 ttatagttta gtctgaatat ttgtttttaa attattacac agcattattt atgtctttag
     4261 tttcagaata acagtgccat taccatatgt ttgtatgttg cagttggata tagctgagac
     4321 tcctccatct tggttttctc ttcactcatc catttcttca gctgcatgat aagtctgtca
     4381 gtaaagcatt taaccccaac aaggtcagac tatggtaaag ttagaaaaac atatttaccg
     4441 aagtacacaa ttgatctcat tgaaataaga agtgagaacc gctctgttga gcactgaggt
     4501 gtaaacgtgc ccagatgcac agcgtgagta gcttcgagta cgcatctgtt tgcacatgtt
     4561 gtagaagctt aaaatgggaa catgaccctg ctgtggagaa ccttggtaga attgttgtta
     4621 gtactaaagg agatttccag cgcatacagg gtggcactga aaactgctga agcccacagc
     4681 cctcagcccc gaaggctcag cggccagtac cagcggcctt gctgtggttg tgtgtctgcg
     4741 tccctggcac acttgggcag gcagctcagt cactctgaac ttgcttctct tctgtcttgt
     4801 gagtgtgctg cttgagacaa tgaaaaataa agctgtgttc ctaccccttc aaaaaaaaaa
     4861 aaaaaaaaaa aaaaaaaaaa aaaaa
//
