LOCUS       NM_026375               8831 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus AT hook containing transcription factor 1 (Ahctf1),
            mRNA.
ACCESSION   NM_026375
VERSION     NM_026375.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8831)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8831)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   3  (bases 1 to 8831)
  AUTHORS   Gao,N., Davuluri,G., Gong,W., Seiler,C., Lorent,K., Furth,E.E.,
            Kaestner,K.H. and Pack,M.
  TITLE     The nuclear pore complex protein Elys is required for genome
            stability in mouse intestinal epithelial progenitor cells
  JOURNAL   Gastroenterology 140 (5), 1547-55 (2011)
   PUBMED   21315719
  REMARK    GeneRIF: In mice, Elys maintains genome stability in intestinal
            epithelial progenitor cells, independent of its role in NPC
            assembly in zebrafish.
REFERENCE   4  (bases 1 to 8831)
  AUTHORS   Campbell,G.R., Baudhuin,A., Vranizan,K. and Ngai,J.
  TITLE     Transcription factors expressed in olfactory bulb local progenitor
            cells revealed by genome-wide transcriptome profiling
  JOURNAL   Mol Cell Neurosci 46 (2), 548-561 (2011)
   PUBMED   21194568
REFERENCE   5  (bases 1 to 8831)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 8831)
  AUTHORS   Suntharalingam,M. and Wente,S.R.
  TITLE     Peering through the pore: nuclear pore complex structure, assembly,
            and function
  JOURNAL   Dev Cell 4 (6), 775-789 (2003)
   PUBMED   12791264
  REMARK    Review article
REFERENCE   7  (bases 1 to 8831)
  AUTHORS   Okita,K., Nobuhisa,I., Takizawa,M., Ueno,M., Kimura,N. and Taga,T.
  TITLE     Genomic organization and characterization of the mouse ELYS gene
  JOURNAL   Biochem Biophys Res Commun 305 (2), 327-332 (2003)
   PUBMED   12745078
  REMARK    GeneRIF: Genomic organization and characterization of the ELYS
            gene.
REFERENCE   8  (bases 1 to 8831)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 8831)
  AUTHORS   Kimura,N., Takizawa,M., Okita,K., Natori,O., Igarashi,K., Ueno,M.,
            Nakashima,K., Nobuhisa,I. and Taga,T.
  TITLE     Identification of a novel transcription factor, ELYS, expressed
            predominantly in mouse foetal haematopoietic tissues
  JOURNAL   Genes Cells 7 (4), 435-446 (2002)
   PUBMED   11952839
REFERENCE   10 (bases 1 to 8831)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122411.4 and AC113977.16.
            
            On Oct 19, 2007 this sequence version replaced NM_026375.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138343.1, AB059278.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-663               AC122411.4         123099-123761       c
            664-791             AC122411.4         118957-119084       c
            792-1045            AC122411.4         115423-115676       c
            1046-1226           AC122411.4         113389-113569       c
            1227-1434           AC122411.4         112092-112299       c
            1435-1551           AC122411.4         110045-110161       c
            1552-1636           AC122411.4         109395-109479       c
            1637-1787           AC122411.4         107935-108085       c
            1788-1920           AC122411.4         106714-106846       c
            1921-2102           AC122411.4         106441-106622       c
            2103-2164           AC122411.4         105816-105877       c
            2165-2293           AC122411.4         104754-104882       c
            2294-2384           AC122411.4         103836-103926       c
            2385-2474           AC122411.4         102693-102782       c
            2475-2615           AC122411.4         101389-101529       c
            2616-2720           AC122411.4         100602-100706       c
            2721-2814           AC122411.4         99350-99443         c
            2815-2938           AC122411.4         97446-97569         c
            2939-2995           AC122411.4         97249-97305         c
            2996-3142           AC122411.4         95754-95900         c
            3143-3330           AC122411.4         95078-95265         c
            3331-3475           AC122411.4         90545-90689         c
            3476-3607           AC122411.4         90335-90466         c
            3608-3758           AC122411.4         89055-89205         c
            3759-3909           AC122411.4         88735-88885         c
            3910-4017           AC122411.4         88041-88148         c
            4018-4210           AC113977.16        235248-235440       c
            4211-4414           AC113977.16        232840-233043       c
            4415-4832           AC113977.16        231915-232332       c
            4833-4932           AC113977.16        229632-229731       c
            4933-5027           AC113977.16        227305-227399       c
            5028-5233           AC113977.16        224819-225024       c
            5234-6995           AC113977.16        221681-223442       c
            6996-7129           AC113977.16        217927-218060       c
            7130-7206           AC113977.16        216550-216626       c
            7207-8831           AC113977.16        214274-215898       c
FEATURES             Location/Qualifiers
     source          1..8831
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 83.62 cM"
     gene            1..8831
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /note="AT hook containing transcription factor 1"
                     /db_xref="GeneID:226747"
                     /db_xref="MGI:MGI:1915033"
     exon            1..663
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            664..791
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     CDS             671..7402
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /note="embryonic large molecule derived from yolk sac;
                     putative AT-hook-containing transcription factor 1"
                     /codon_start=1
                     /product="protein ELYS"
                     /protein_id="NP_080651.2"
                     /db_xref="CCDS:CCDS15564.1"
                     /db_xref="GeneID:226747"
                     /db_xref="MGI:MGI:1915033"
                     /translation="MQDLTAQVTSDLLHFPEVTIEALGEDEITLESVLRGKFAAGKNG
                     LACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEAD
                     GSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVT
                     DVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRERVMREGRHLCFQLVSP
                     LGVAISTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVHAVAFQEPE
                     NDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLD
                     LAGGTFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQ
                     GKPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLDSVVSRTSPHHILDILV
                     HERSLNRGVPPSYPPPEQFFNPSTFNFDATCLLDSGVIHVTCAGFQKETLTFLKKSGP
                     TLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIR
                     TWIIEEQPNSAANLRFVLEWTWNKVVLTKEEFDRLCVPLFDGSCRFIDPQTIQSIQQC
                     HLLLSNLSTVLSCFAMEAQGITERGLVDLSNKHMVTQLLCQYAHMVLWFCHSGLLPEG
                     LDDALQLSRLRYNYPVIQNYYTSRRQKSERSPRGKWNHDCLMIDGLVSQLGDEVEKLW
                     KRDEGGTGRYPPASIHALLDIYLLDNITEASKHAITIYLLLDIMYSFPNKTDTPIESF
                     PTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEH
                     KQALRYLQTMKPTVSSSNEVILHLTVLLFNRCMVEAWNLLRQNSNRVNIEELLKHAYE
                     VCQEMGLMEDLLKLPFTNTEQECLVKFLQSSTSVENHEFLLVHHLQRANYISALKLNQ
                     ILKNNLMSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFHEV
                     SRPKPLSAFPKKAITGTVLTRSTFISNVLSKIGEVWASHEPRNGVSLFNSPKTEQPSP
                     VVHSFPHPELPEAFVGTPISNTSQRISRLLDLVVHPVPQPSQCLEFIQQSPTRSPLCL
                     LSSSLPLSSQFKRPHQNTSRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILR
                     SGFRTTPLASPSLSPGRSLTPPFRVKETRISFMEEGMNTHWTDRATDDRNTKAFVSTS
                     FHKCGLPAETEWMKTSDKNTYFPLDVPAKGPQKVVAESLATHSGRLEKLDVSKEDSTA
                     STRSDQTSLEYHDAPSPEDLEGAVFVSPKPASSSTELTTNSTLQTERDNDKDAFKSEG
                     APSPVKKQIGTGDAAVEAFSELSRLDPVERAEASFAVSSVCEGETSTSNSKTSVLDGI
                     VPIESRTSILTADHKESVANTVADVESSGSTSSKCPVTSERSLGQKLTLNLKEDEIEA
                     HVPKENVGLPEESPRISAAPSDTHEIHLIGCENLEVQNSEEEAKNLSFDELYPLGAEK
                     LEYNLSTIEQQFCDLPDDKDSAECDAAEVDGELFVAQSNFTLILEGEEGEAEASDSAA
                     PNMLPKATKEKPVCHREPHNQERVTDLPSAVTADQESHKVETLPYVPEPVKVAIAENL
                     LDVIKDTRSKEATPVAAGEAGDEDGAVIVSKAAHSSRLTNSTPKTVKEPHAETVNTSQ
                     NDDMVSSRTLTRRQHALSLNVTSEQEPSAVATPKKRTRKIKETPESSERTCSDLKVAP
                     ENQLTAQSPPAPRRGKKKDVSQGTLPSSGAVEPEPEPQGTPGRLRLRTQPPEPAAEET
                     PSRTKVRLSSVRKGTPRRLKKSVENGQSTEILDDLKGSEAASHDGTVTELRNANLEDT
                     QNMEYKQDEHSDQQLPLKRKRVREREVSVSSVTEEPKLDSSQLPLQTGLDVPATPRKR
                     GRPRKVVPLEADGGTTGKEQTSPQKKDVPVVRRSTRNTPARNVSTLEKSVLVPNKEAA
                     LVVTSKRRPTKKSAEESSKDPSAAVSDLAGGAAHTESADRRDGLLAAAALTPSAQGTR
                     TRSRRTMLLTDISEPKTEPLFPPPSVKVPKKKSKAENMEAAAQLKELVSDLSSQFVVS
                     PPALRTRQKSISNTSKLLGELESDPKPLEIIEQKPKRSRTVKTRASRNTGKGSSWSPP
                     PVEIKLVSPLASPVDEIKTGKPRKTAEIAGKTLGRGRKKPSSFPKQILRRKML"
     exon            792..1045
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1226
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1434
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1551
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1636
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1787
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1920
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2102
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2164
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2293
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2384
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2385..2474
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2475..2615
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2720
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2814
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2815..2938
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2939..2995
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..3142
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            3143..3330
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            3331..3475
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            3476..3607
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            3608..3758
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            3759..3909
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            3910..4017
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            4018..4210
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            4211..4414
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            4415..4832
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            4833..4932
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            4933..5027
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            5028..5233
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            5234..6995
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            6996..7129
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            7130..7206
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     exon            7207..8831
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7626..7631
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /note="hexamer: AATAAA"
     polyA_site      7644
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /note="major polyA site"
     regulatory      8380..8385
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /note="hexamer: AATAAG"
     polyA_site      8398
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
     regulatory      8723..8728
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
                     /note="hexamer: ATTAAA"
     polyA_site      8742
                     /gene="Ahctf1"
                     /gene_synonym="6230412P20Rik; Elys"
ORIGIN      
        1 gcagtcatag acggaaagat tatcgcttgg ctgccagcag gaaccgccac tagattaggc
       61 cggcccttgc tccgcaaagc cggacacgcc ctacactacg cccagcgcac aaagccctat
      121 gggacttgta gtctttcgcc tatctgctcc taggaggcgg agagaccctg ctgtacgtaa
      181 atgaatcttt cttcccggcg tcgtctcggt tttctccctt tgcgaaaggc ctagtaggga
      241 aagtttgaaa attcccgcgg agtcggcgcc agaggccgga accctcgcga gaagtccgag
      301 ccccgcagcg cgatctgcga tcggatcccc gccctggcca cgatccttcc ctgggcggag
      361 aggctgtgtg tgtggggttc gggcagtgcg cccggggtaa tgcgcagagc gcggcccgag
      421 cggtgccagc ccagtaagtc gagtcgccag cggggaggac gcggcgcggg cggtgggacg
      481 agttcgaagc cgggattggg cgaaggagca cccggggcct gaggggaccg gcgagagact
      541 gagcgagaag cggcttccgc gggcccgggg cgcgcgccgg gccgtgtctc ccgggagatg
      601 ctgtgacgga ccgcacggaa gcagcgacgc cggggccctt ggcggcctgg cccgcgggct
      661 cagtggcagt atgcaagact tgacagctca agtgactagt gatctcctgc atttcccaga
      721 agtgactatt gaagctcttg gagaagatga gataacatta gagtccgtgc ttcgtggaaa
      781 gtttgctgca gggaaaaatg gactagcatg cttagcttgt ggtccacaac ttgaagttgt
      841 aaactcccta acaggagagc ggttatctgc atatagattc agtggagtaa atgaacagcc
      901 tcctgtagtc cttgcagtga aagaattctc ttggcataag aggactggat tgttaatagg
      961 attggaagaa gcagatggga gtgttctttg tctttatgac cttggtatat caagagtggt
     1021 caaagcagtt gttcttcctg gaagggtaac agctatcgag cctataatta accatggagg
     1081 agccagtgcg agtacccagc atttacatcc aagtctccgg tggctttttg gcgtggccgc
     1141 tgtggtgact gatgttggac agatccttct tattgacctg tgtttggatg acttgtcctg
     1201 cagtcagaat gaagttgagg catcagacct tgaagttatc actggtatcc cagctgaagt
     1261 accacacatc agagagagag tgatgagaga ggggcgccac ctgtgcttcc agttagtaag
     1321 cccattggga gtagccattt ctactctgag ttacatcaac aggacaaatc agcttgctgt
     1381 gggtttttct gatggctact tagcactttg gaacatgaaa agcatgaaaa gagaatacta
     1441 tacacagttg gaaggtggaa gggttcctgt ccatgcagtt gcctttcaag agcctgagaa
     1501 tgatcctcgt aactgctgtt atttatgggc tgttcagtcc acacaagata gtgaagggga
     1561 tgttttgagt ttgcatctgc ttcagctggc ttttggtgat agaaaatgtt tggcatcagg
     1621 gcaaatttta tatgagggat tagaatactg cgaagaaaga tatacactgg atctagcagg
     1681 tggcacgttc cccttaaggg gacaaactag taataccaaa ttgttgggat gccagagtat
     1741 agagagattt ccatctcatg gagacagaga agaaagtatg agagaagctc tgtctcccga
     1801 taccagcgtt tctgtcttta cctggcaagt gaatatatat ggacagggaa agccttctgt
     1861 gtatttaggg ctatttgaca taaatcgttg gtatcatgca caaatgcccg attctttaag
     1921 atcaggagaa tctctgcata attgctctta ttttgcgttg tggtcattgg attcggttgt
     1981 aagtaggact tctccacatc acatcttgga catactagta catgagagga gtttaaaccg
     2041 aggggttcct ccttcctacc cacctccaga gcaatttttt aacccaagta cttttaattt
     2101 tgatgccact tgtttgttag actctggagt tatccatgta acttgtgctg gatttcagaa
     2161 ggagactttg acatttttaa agaaatcagg accaactctt aatgaagtca ttcctgatag
     2221 ttataatcga tgtcttgttg ctggtctcct ctcaccaaga cttattgata ttcagccttc
     2281 cagtttaagt caagaagaac aattagaagc tatattgtca gcagcaattc agacaagttc
     2341 cttgggactt ttgactggtt acatcagaac gtggataata gaagaacaac caaattctgc
     2401 tgctaatcta cgatttgttc ttgagtggac atggaataaa gtggttctca caaaagaaga
     2461 gtttgatagg ctttgtgtgc cgctgtttga cggttcgtgt cgttttattg acccacagac
     2521 tattcagtct atccagcagt gccatttact gcttagcaac cttagtacag tcttaagctg
     2581 ttttgcaatg gaggcccagg gtatcactga gagaggactg gtggacttga gcaacaagca
     2641 catggtcacc cagcttctct gtcagtacgc acacatggtt ctgtggttct gccactcggg
     2701 gcttctgccc gaaggcttag atgatgctct gcagctgtca agactacgct acaactaccc
     2761 tgtaattcag aactactata caagtcgtcg gcagaagtct gagcgctcac ccagagggaa
     2821 gtggaaccac gactgcttga tgattgatgg attagtctct caactaggag atgaagttga
     2881 gaagttgtgg aagcgggacg aaggtggcac aggaagatac cctcctgcta gcatccacgc
     2941 attacttgat atatatttat tagacaacat taccgaagca agcaaacatg ctattaccat
     3001 ttatttgctg cttgatatta tgtattcctt tccaaataaa acggataccc ccattgaatc
     3061 tttcccaact gcctttgcta tttcttgggg ccaagttaag ctagttcaag gattttggct
     3121 gctagatcat aatgactatg agaatggttt agaccttctg tttcacccag ttactgcaaa
     3181 gcctgcatcg tggcaacatt caaagataat tgaagctttt atgagtcagg gagagcacaa
     3241 acaggctctc cggtatcttc agacaatgaa gccaacagtg tccagtagca atgaagttat
     3301 ccttcacctc actgttctac tttttaatag atgcatggtt gaggcctgga acttactgcg
     3361 acagaattca aacagagtaa atatagagga attattaaag cacgcttatg aagtttgtca
     3421 ggagatgggc ttaatggagg atttactgaa gctgccattt acaaacactg agcaggaatg
     3481 cttagtgaaa tttttacagt ccagtaccag tgttgagaat catgaattcc ttctagttca
     3541 ccatttacag cgtgccaatt atatttctgc cttgaaacta aaccagattc tgaagaataa
     3601 tctcatgagt gatcgtgacc ctcgattgcg ggaaagatcg gtgactcgaa attctatatt
     3661 agaccagtat gggaaaatcc tacctagagt ccagagaaag ttagctgttg agcgagctaa
     3721 gccttaccac ctgtcgacat cctcagtttt tcatgaagtt tctagaccca aaccgttatc
     3781 ggcatttcca aagaaagcta taactggaac agtgttaacc cgatctacgt tcatcagcaa
     3841 tgttttatct aaaattggag aggtgtgggc aagtcatgag cctagaaatg gcgtctcact
     3901 ttttaacagt cctaaaacag aacagccatc tcctgtagta cactctttcc cacacccaga
     3961 gcttcctgag gcgtttgttg gaactccaat ttcaaataca tcccagagaa tttctagatt
     4021 actggatttg gttgtccatc ctgtacccca gccttctcag tgtttggagt ttattcaaca
     4081 aagtcccaca agatctcctt tgtgtctgct gtccagttcg ttaccattaa gttcacagtt
     4141 taaaaggcca catcagaata cctccaggcc ttcagagttg cttttacttg agactcctct
     4201 catagttaag aaagctaaat ctttggctct gtcagccacg tcttctggat ttgccgagtt
     4261 tactcctcca tccatcctta ggtctggttt tcgaacaaca cctttagcat ctccctcttt
     4321 gtcacctgga agatctctca ctccgccttt cagagttaaa gaaacaagga tttcattcat
     4381 ggaagaaggc atgaatacac actggactga tagagctaca gatgaccgaa atacaaaagc
     4441 gtttgttagc acatctttcc ataaatgtgg acttccagca gaaactgagt ggatgaagac
     4501 cagtgataag aatacatatt ttcctctgga tgtccctgca aagggccctc agaaagtggt
     4561 ggcagagtca ctggctaccc attcaggaag gctggagaaa ctggatgtga gcaaagaaga
     4621 cagcacagct tccaccaggt cagaccagac ctccttagag tatcatgacg caccatcacc
     4681 agaagacttg gaaggtgctg tttttgtgtc tcccaagcca gcatcttcct ccactgaact
     4741 aactactaat tcaactctac aaacagagag ggataatgat aaagatgcgt ttaagtcaga
     4801 aggtgctcct tcacccgtga agaaacaaat aggcacggga gatgctgcag tggaagcatt
     4861 ttcagaactg agtcgcttag accctgttga aagagctgaa gcttcttttg ctgtgtcgtc
     4921 agtctgtgaa ggggaaacct ccacttcaaa ctccaagacg tcagttctgg atggaatcgt
     4981 gcctattgag agccgaacct ccatacttac agcagaccac aaagagtctg tggccaacac
     5041 ggttgcagat gttgaaagct ctgggtccac cagctccaag tgcccggtta cctctgaacg
     5101 cagcctcggc caaaaactaa cattaaactt aaaagaagat gaaatagaag ctcatgtacc
     5161 aaaggagaac gttggtttac cagaagaaag ccctcgaatt tctgctgctc cttctgatac
     5221 tcacgagatt catctaattg gatgtgaaaa tcttgaagtt caaaattcag aagaggaggc
     5281 caagaatctt tcatttgatg agttgtatcc cttaggggca gagaaacttg agtataatct
     5341 cagtactatt gagcagcagt tttgtgactt gcctgatgac aaagactctg ctgaatgtga
     5401 tgctgctgaa gtagacgggg aactttttgt ggcccagagc aactttaccc tgattttaga
     5461 aggtgaagaa ggagaagctg aggcaagcga ctctgcagca cctaatatgt taccgaaagc
     5521 gaccaaggaa aaacctgtgt gccacaggga accccataat caggagcgcg ttacagattt
     5581 gccatctgct gtgactgctg accaagaatc ccacaaggta gagactttac cgtatgtgcc
     5641 tgaaccggtt aaagtggcaa ttgcagaaaa tctgttggat gtaattaaag acaccagaag
     5701 taaggaagca actcccgtgg cagcaggtga ggctggtgat gaggacggag cagtgatagt
     5761 ctcaaaggct gcacattcgt ccaggctgac aaactctaca ccgaagactg ttaaggaacc
     5821 acatgcagag actgtaaata ccagccagaa tgatgacatg gtttcttcta gaactctcac
     5881 aagaaggcag catgccctaa gcctgaatgt cacatcagaa caagagcctt cagcagttgc
     5941 cactcctaag aagagaacta gaaaaattaa agaaactcct gagtcttctg aaaggacctg
     6001 ttctgaccta aaagtagcac ctgagaacca actgacagct cagagtcctc ccgctcctag
     6061 gagaggaaag aagaaggacg ttagccaagg cacactgcca agttctggtg ctgtggagcc
     6121 ggagccggaa cctcagggta cgccgggaag actgaggctg agaacgcagc cacccgagcc
     6181 agcagctgaa gaaactcctt ctagaacaaa agtcaggctt tcatctgtta gaaagggaac
     6241 ccctagaaga cttaagaagt ctgtagaaaa tgggcaaagt acagaaattc tagatgatct
     6301 caaagggagt gaggcagcaa gtcatgacgg gactgtcaca gagctgagga atgccaattt
     6361 agaagatact cagaatatgg agtataaaca agatgaacac agtgaccagc aactgcctct
     6421 aaaacgaaag agggtcagag agagagaagt tagtgtgtca agtgtgacag aagagccaaa
     6481 gcttgactca tcccagttgc ctcttcagac aggactcgat gtacctgcca cccctaggaa
     6541 acgtggtaga cccaggaagg tagttccctt agaagctgat ggtggcacaa ctggtaagga
     6601 acagacaagt cctcagaaga aagatgttcc ggttgtccgg agatctacac ggaacacccc
     6661 agctagaaat gtgagtactt tagaaaaatc agttttagtg ccaaataagg aagctgctct
     6721 agtggtgaca tctaagagga gacctacaaa gaagtctgca gaggaaagct caaaagatcc
     6781 atcagcggca gtctcagacc tggcgggtgg agcagcccac acagagtccg ctgaccgaag
     6841 ggacggactg cttgccgccg ctgctctcac gccatctgcc cagggcacaa ggactaggtc
     6901 tagaaggacc atgttgttga cggacatttc tgaacccaaa actgagcctt tatttcctcc
     6961 tccttcagtg aaggttccaa agaaaaaatc aaaagctgag aacatggagg ccgcagccca
     7021 gctgaaagaa ttggtgtcag atttatcttc tcagtttgtt gtttcccctc ctgccttgag
     7081 aaccaggcag aaaagtatat ccaatacttc caagcttcta ggtgaactgg agagtgaccc
     7141 taaaccatta gagatcatag aacaaaaacc aaaaagaagc aggactgtga agacaagagc
     7201 aagcagaaac acaggaaaag gaagttcttg gtcacctcct cctgtagaaa ttaagctggt
     7261 ttctcccttg gcgagtccag tggatgaaat aaagaccggc aagccaagaa aaactgcaga
     7321 aatagcagga aaaactcttg gaaggggcag aaagaagcca tcttcttttc caaagcaaat
     7381 tttacgcagg aaaatgctgt aatttttagc ccaagatttt aacacgcacc tgtttgtaaa
     7441 agtcaacagt atttgtgtgg attattaaag tcaccaattt ggatggaaat actttatata
     7501 aattgtacaa ttttgtaagc agtaaatgag taactccaca tggagtgcag ttcttgtagt
     7561 gcaggcgttt tatacgactt gatgcgttta tatcaatgta aatatgactt atcattggga
     7621 ggttaaataa actactgtaa agtacactgt gtgtctggta gatttttgag aggagctttc
     7681 tgtttgagtt gtaattttat atgctactgg acatatgttc atatcctttc tttacagtta
     7741 agatactaga actgtcttaa aatgagggcg atgaactatt gattattttt aacattgctg
     7801 ttttataatg tatgcacttt gatgctgttc ctcggatctc tggtcagtac ctgtgctcat
     7861 tgggctttgc ctgatactgt gttgaatttg aattgtgggc atgtgatttt gcctttttgt
     7921 agttttacaa atgttgtgta atctacctca aatgagtaat tttccagtac tgcatcggtt
     7981 tcctagctag cagttctctt cagtaactta aggactatct tgtctctcag ttcagagact
     8041 taattatcca ggttagattg accggtttca ctgcttccta gcaacctcat ggaaggattg
     8101 aagaaagaaa taaaacagtg caccgacgtg tgcctgctgc tgagaagagg agccgacaag
     8161 gtttagactt cccatgctgt gaaagagctt gcgacttcgt cacaggagcc tctctagtat
     8221 tcaggtttta aactggtaac tgccacagaa cctcaggcac aggttacaga gaatggaaga
     8281 gtgtgagcag atgtcggaaa agaggaaagg aaccctcttt tctgcagcgt gtgtaccgtt
     8341 ggtaatggcg cctgatggaa gccatgatgt tcatcaataa ataagtgttg tcaaataatt
     8401 tatgacaggt aattgatagt gtgtaatgaa tggacgctta ataattgata cctaaaagca
     8461 gactttgtca gctaagcttt ggatgttttc gtgagcagtg tgctttgtgt gttatttttc
     8521 taccgagtag catcatggat aatgagaaaa tggggagagt gcctgtgccg agatcggaca
     8581 gtgtgagagt ggccgtccgg gtgcggccgt tcagccaggt cagtccatgc tcattgcctt
     8641 gctgacaatt actgcctgat tttattaatt ttttaataat agtttctgaa tttgtattta
     8701 agctgcttgt catttatgaa atattaaact tatttaaatg gatttgtcaa atgattcaca
     8761 aaagctctaa gcataattta gtaaacattt aatttcattc cttggtacaa gtagcacaat
     8821 aaaaaaaact g
//
