LOCUS       NM_207531                819 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus anterior gradient 3 (Agr3), mRNA.
ACCESSION   NM_207531 XM_354667
VERSION     NM_207531.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 819)
  AUTHORS   Bonser,L.R., Schroeder,B.W., Ostrin,L.A., Baumlin,N., Olson,J.L.,
            Salathe,M. and Erle,D.J.
  TITLE     The Endoplasmic Reticulum Resident Protein AGR3. Required for
            Regulation of Ciliary Beat Frequency in the Airway
  JOURNAL   Am J Respir Cell Mol Biol 53 (4), 536-543 (2015)
   PUBMED   25751668
REFERENCE   3  (bases 1 to 819)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BE650904.1, AK053177.1 and AW490945.1.
            
            On Dec 17, 2009 this sequence version replaced NM_207531.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053177.1, BC023499.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                BE650904.1         1-72
            73-405              AK053177.1         2-334
            406-406             AW490945.1         437-437             c
            407-819             AK053177.1         336-748
FEATURES             Location/Qualifiers
     source          1..819
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 15.97 cM"
     gene            1..819
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /note="anterior gradient 3"
                     /db_xref="GeneID:403205"
                     /db_xref="MGI:MGI:2685734"
     exon            1..107
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     exon            108..243
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..635
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /note="anterior gradient protein 3 homolog; anterior
                     gradient homolog 3"
                     /codon_start=1
                     /product="anterior gradient protein 3 precursor"
                     /protein_id="NP_997414.2"
                     /db_xref="CCDS:CCDS25880.1"
                     /db_xref="GeneID:403205"
                     /db_xref="MGI:MGI:2685734"
                     /translation="MLHSALALCLLLITVSSNLAIAIKKEKRPPQTLSRGWGDDITWV
                     QTYEEGLFHARKSNKPLMVIHHLEDCQYCQALKKEFAKNEEIQEMAQNDFIMLNLMHE
                     TTDKNLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYTYEPQDLPMLVDNMKKALRL
                     IQSEL"
     exon            244..307
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     exon            308..360
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     exon            361..437
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     exon            438..501
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     exon            502..585
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
     exon            586..819
                     /gene="Agr3"
                     /gene_synonym="BCMP11; E030025L21Rik; Gm888"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctatgcaggt gaagttgtag gtcaggtgtg tgtgcttata aatccacacc ccttcgcaac
       61 gcgtaacatc caaaacacgt ttctaacaag agcgctgggc agctcagctg cctctgagtg
      121 actctataga agataagatg ctacattccg ctctggccct ctgcctcttg ctgatcacgg
      181 tttcttcaaa ccttgccatt gctatcaaaa aagaaaagag acctcctcag acactctcaa
      241 gaggatgggg agatgacatc acatgggtgc aaacttacga agaaggtctc tttcatgctc
      301 gcaaaagtaa caaaccactg atggttattc accacctgga ggactgtcag tactgtcaag
      361 cactaaaaaa ggaatttgcc aaaaatgaag aaatacaaga aatggcacaa aatgacttca
      421 tcatgctgaa tctcatgcat gagaccacgg acaagaactt gtcacctgat gggcagtacg
      481 tgcccaggat catgtttgtt gacccttctt tgactgtcag ggctgatata actggaagat
      541 actctaacag actatacacg tatgaacccc aggacttacc catgttggta gacaacatga
      601 agaaagcact aagacttatc cagtcagagt tgtaaggaat atggaaagat gcttccactc
      661 gaagaggtca aacatgtggt acaaacatct ggttcactaa caaataccaa atgtgcaagt
      721 ccatggattt ttataacatc actatttggc tttgtgacat gtctgtgata gtttatgaag
      781 gtaaaattat attttaataa atgttaaact ctgtggttt
//
