LOCUS       NM_153177               6527 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus argonaute RISC catalytic subunit 4 (Ago4), mRNA.
ACCESSION   NM_153177
VERSION     NM_153177.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6527)
  AUTHORS   Zhang,Y., Tan,Y.Y., Chen,P.P., Xu,H., Xie,S.J., Xu,S.J., Li,B.,
            Li,J.H., Liu,S., Yang,J.H., Zhou,H. and Qu,L.H.
  TITLE     Genome-wide identification of microRNA targets reveals positive
            regulation of the Hippo pathway by miR-122 during liver development
  JOURNAL   Cell Death Dis 12 (12), 1161 (2021)
   PUBMED   34907157
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6527)
  AUTHORS   Adiliaghdam,F., Basavappa,M., Saunders,T.L., Harjanto,D.,
            Prior,J.T., Cronkite,D.A., Papavasiliou,N. and Jeffrey,K.L.
  TITLE     A Requirement for Argonaute 4 in Mammalian Antiviral Defense
  JOURNAL   Cell Rep 30 (6), 1690-1701 (2020)
   PUBMED   32049003
REFERENCE   3  (bases 1 to 6527)
  AUTHORS   Hajarnis,S., Yheskel,M., Williams,D., Brefort,T., Glaudemans,B.,
            Debaix,H., Baum,M., Devuyst,O. and Patel,V.
  TITLE     Suppression of microRNA Activity in Kidney Collecting Ducts Induces
            Partial Loss of Epithelial Phenotype and Renal Fibrosis
  JOURNAL   J Am Soc Nephrol 29 (2), 518-531 (2018)
   PUBMED   29021386
REFERENCE   4  (bases 1 to 6527)
  AUTHORS   Zheng,Y., Guo,X., He,W., Shao,Z., Zhang,X., Yang,J., Shen,Y.,
            Luo,X. and Cao,J.
  TITLE     Effects of Echinococcus multilocularis miR-71 mimics on murine
            macrophage RAW264.7 cells
  JOURNAL   Int Immunopharmacol 34, 259-262 (2016)
   PUBMED   26995025
  REMARK    GeneRIF: up-regulated in murine macrophage RAW264.7 cells
            transfected by Echinococcus multilocularis miR-71
REFERENCE   5  (bases 1 to 6527)
  AUTHORS   Modzelewski,A.J., Holmes,R.J., Hilz,S., Grimson,A. and Cohen,P.E.
  TITLE     AGO4 regulates entry into meiosis and influences silencing of sex
            chromosomes in the male mouse germline
  JOURNAL   Dev Cell 23 (2), 251-264 (2012)
   PUBMED   22863743
  REMARK    GeneRIF: show that Ago4(-/-) spermatogonia initiate meiosis early,
            resulting from premature induction of retinoic acid-response genes
REFERENCE   6  (bases 1 to 6527)
  AUTHORS   Lu,J., Qian,J., Chen,F., Tang,X., Li,C. and Cardoso,W.V.
  TITLE     Differential expression of components of the microRNA machinery
            during mouse organogenesis
  JOURNAL   Biochem Biophys Res Commun 334 (2), 319-323 (2005)
   PUBMED   16036130
REFERENCE   7  (bases 1 to 6527)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 6527)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   9  (bases 1 to 6527)
  AUTHORS   Doi,N., Zenno,S., Ueda,R., Ohki-Hamazaki,H., Ui-Tei,K. and Saigo,K.
  TITLE     Short-interfering-RNA-mediated gene silencing in mammalian cells
            requires Dicer and eIF2C translation initiation factors
  JOURNAL   Curr Biol 13 (1), 41-46 (2003)
   PUBMED   12526743
REFERENCE   10 (bases 1 to 6527)
  AUTHORS   Carmell,M.A., Xuan,Z., Zhang,M.Q. and Hannon,G.J.
  TITLE     The Argonaute family: tentacles that reach into RNAi, developmental
            control, stem cell maintenance, and tumorigenesis
  JOURNAL   Genes Dev 16 (21), 2733-2742 (2002)
   PUBMED   12414724
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB616446.1, BC096023.1, AK017827.1, AV306945.1 and AI481660.1.
            
            On Jan 9, 2009 this sequence version replaced NM_153177.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC096023.1, AK030018.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-608               BB616446.1         1-608
            609-3912            BC096023.1         391-3694
            3913-6354           AK017827.1         1118-3559
            6355-6477           AV306945.1         133-255
            6478-6519           AK017827.1         3683-3724
            6520-6527           AI481660.1         1-8                 c
FEATURES             Location/Qualifiers
     source          1..6527
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 60.9 cM"
     gene            1..6527
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="argonaute RISC catalytic subunit 4"
                     /db_xref="GeneID:76850"
                     /db_xref="MGI:MGI:1924100"
     exon            1..274
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     CDS             256..2841
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="Piwi/Argonaute family protein meIF2C4; argonaute 4;
                     eukaryotic translation initiation factor 2C, 4; argonaute
                     RISC catalytic component 4"
                     /codon_start=1
                     /product="protein argonaute-4"
                     /protein_id="NP_694817.2"
                     /db_xref="CCDS:CCDS18654.1"
                     /db_xref="GeneID:76850"
                     /db_xref="MGI:MGI:1924100"
                     /translation="MEALGPGPPASLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDV
                     YHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDR
                     IDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLP
                     SMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQ
                     PIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTR
                     RPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKHPHLPCLQVGQEQKHTYLPLEVC
                     NIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIV
                     VHNEMTELTGRVLPAPMLQYGGRNKTVATPSQGVWDMRGKQFYAGIEIKVWAVACFAP
                     QKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQ
                     LIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKMNAKLGGI
                     NNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQ
                     TSRQEITQELLYSQEVVQDLTSMARELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVA
                     WPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKMERVGKSGNVPAGTTVDS
                     TVTHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRS
                     VSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQH
                     TMYFA"
     exon            275..440
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            441..561
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            562..743
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            744..880
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1015
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1103
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1251
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1371
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1500
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1634
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1819
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1979
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2295
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2430
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            2431..2532
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            2533..2732
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            2733..6523
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6498..6503
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="hexamer: AATAAA"
     polyA_site      6523
                     /gene="Ago4"
                     /gene_synonym="5730550L01Rik; Eif2c4"
                     /note="major polyA site"
ORIGIN      
        1 gctcccgttc cagctggcgg cggcggcggc agcggccggg attgtttttg ttgtcgctga
       61 ggccggaaga gccgtgacag agtcgggtcc ctgtccccgg actgggcgcc gccgccgccc
      121 cctgcccgcc cccggcccgc gtcttcgcgg cgccgcttca gcgccaatat tccagagagc
      181 aagcgttacg cggctccggc ggggcccgga gcgggaggcg ctggggaccg gagcgaggcg
      241 gcccccgtcg ccgccatgga ggcgctggga cccggacctc cagccagcct cttccagcca
      301 cctcggcgtc ctggccttgg aaccgttggg aaaccaattc gactgttagc caatcatttt
      361 caggttcaga tccctaaaat agatgtgtat cactatgatg tggatattaa accagaaaaa
      421 cggcctcgta gagtcaacag ggaggtggta gacactatgg tgcggcactt caagatgcag
      481 atatttggag atcggcagcc tggctacgat ggcaaaagaa acatgtacac ggcacaccca
      541 ctgccaatcg gacgggatag gattgatatg gaggtgaccc tcccaggtga gggtaaagac
      601 caaactttca aagtgtctgt gcagtgggtg tcagttgtga gccttcagct gcttttagaa
      661 gctttagcag gacacctgaa tgaagtccca gatgactcag tacaagcact tgatgtgatt
      721 acaaggcatc tcccctctat gaggtacact ccagtaggcc ggtctttttt ctcacctcct
      781 gaaggttatt accaccctct gggagggggc agagaggttt ggtttggctt tcatcagtct
      841 gtgagacctg ccatgtggaa tatgatgctc aatattgatg tatctgcaac tgctttctac
      901 cgggctcaac ctatcattga gttcatgtgt gaggttttag acattcagaa catcaatgag
      961 cagacaaaac ctctaacaga ctcccagcgt gtcaagttta ccaaagaaat taggggtctt
     1021 aaggttgagg tgactcactg tggacagatg aaacgaaaat atcgagtttg taatgtgaca
     1081 agacggccag ccagtcatca aaccttccct ttgcagctag agaatggcca agctatggaa
     1141 tgtacagtgg ctcagtattt taagcagaag tatagtctgc agctgaaaca cccccacctt
     1201 ccctgccttc aagtggggca agagcaaaag catacctacc taccacttga ggtctgtaat
     1261 atagtggcag gacagagatg tataaagaag ctcacagaca atcagacatc caccatgatc
     1321 aaagccacgg caagatctgc tcctgacaga caggaggaaa tcagtagact ggtgaagagc
     1381 aacagcatgg tgggtggacc tgacccatac ctgaaggaat ttgggattgt tgtgcacaac
     1441 gagatgacag agctcacagg cagggtgctt ccggctccaa tgctgcagta tggaggccgg
     1501 aataaaacag tagccacacc cagccagggt gtctgggaca tgcgaggaaa acagttttat
     1561 gctggcattg aaattaaagt atgggcagtg gcttgttttg cgcctcagaa acaatgtagg
     1621 gaagatttgc taaagagttt cactgaccaa cttcgtaaaa tctccaagga tgcagggatg
     1681 cccatccagg gtcagccatg tttctgcaag tatgctcaag gtgcagacag cgtggagccc
     1741 atgtttaaac atctgaaaat gacatatgtg ggcctgcagc taatagtggt gattttgcct
     1801 gggaagacac cagtatatgc ggaggtgaag cgtgttggag atacccttct aggtatggcc
     1861 acacagtgtg tccaggtcaa aaacgttgtg aagacctcgc cccagaccct ttccaacctt
     1921 tgcctgaaga tgaacgcaaa gctgggaggg attaacaatg tgcttgtgcc tcaccaaagg
     1981 ccctcagtgt tccagcagcc tgtcatcttt ctgggagcag atgtcactca tccgcctgct
     2041 ggggacggga agaagccttc tattgcagcc gtggtgggca gcatggacgg ccatcccagc
     2101 cggtactgtg ccacagtccg ggtacagaca tctcgacagg agatcaccca ggagctcctc
     2161 tacagccagg aggtcgtgca ggacctgacg agcatggctc gggagctgct gattcaattc
     2221 tataagtcca cgcgcttcaa gcccacacgc atcatctact accgcggagg ggtatccgag
     2281 ggacagatga agcaggtagc ttggccggag ctaatagcaa ttcgaaaggc atgtataagc
     2341 ttggaggaag actatcggcc gggaataact tacattgtgg tgcaaaagag gcaccacaca
     2401 cgactcttct gtgcagataa aatggaaagg gtggggaaaa gtggcaatgt cccagcaggc
     2461 accacagtgg atagcaccgt cacacacccg tctgagtttg acttttacct ctgtagtcat
     2521 gcaggaattc agggaaccag ccgtccttca cattaccagg tcttgtggga tgacaactgc
     2581 ttcactgcag atgaactcca gctactgact taccagctct gtcacaccta cgtgaggtgc
     2641 acacgctccg tctccattcc tgcccctgca tattatgccc ggcttgtggc attccgggca
     2701 aggtatcatt tggtggataa agatcatgac agtgcggaag gcagtcacgt gtcaggacag
     2761 agcaacggcc gggatcctca ggccttggct aaggctgtgc agatccacca tgatacccag
     2821 cacactatgt attttgcctg agagtcttgg aaaagaactc aacaaatttg gcatctcacg
     2881 catcctcaaa atgtttccga cgcctactgc ctctctcagg tggtccctac cagcagctca
     2941 gaatggttgc actgagtcta ctctgcagcc ctgtctgata catcaacaaa attgagccag
     3001 ttgggttttt ttgttaaaga aatagatact catagattgt gttttctgat gcactgggca
     3061 gaatttttac ctcaacgtgc aaaggctgat cagccttgac tttctaaagg actttccaag
     3121 aagggtttct atggaatctt ttgctagctg tggtattcac cgcatctagt cttataagag
     3181 gagtatttcc ttttttctgt gtttattgaa tggtgtgcat aagtgggaga gagaaaccaa
     3241 acggcctgta tcatttccat gtaacttttt aattgggtgg gtccatagac ctcttacttc
     3301 tgactttgcc actgtcaatg cctttaagga gcatcagctt ttgaaagttt tacagaactc
     3361 tgttaccttc actgttctac tgatctcttc gggcctgcac tgtggggtac aggctgccca
     3421 gcaattgcac tatatttggc tgcagattcg aacaggcagt tcccttactt gactggcttt
     3481 tgtgagtctg tgacataagc agatgtgatg tgtgtcacag ggacagatac actgccgtgg
     3541 taaaaagtac ccatgttttc catatttgga aaaagagaat tagcttttag tatttttcca
     3601 catcttcaaa catgcccatt ttatgctgct gtgtggtatg ctagatctaa acgatcttta
     3661 aacttctctc atagaaagtt aactttggca ataagcattt gtaaggccct tgccctttct
     3721 cctgacgtcg ttttctagat gagatttcag tatgatttta tcaactattt cttacatatc
     3781 ataactggga tattctgaaa ccagtttata aagacacaga tttcaatgtc cttataaata
     3841 attgttttta aaacaaaaca aaacaaaact tattttatag tcagtgtcct gtcactttaa
     3901 aaaaaaaaaa aagaagctgg aaccaggatg ctttgtgatc ggtcaggctt tgccgatgca
     3961 taaggcacat tgagcagtac tgcacttgaa aagaaagtac cagccagtga aaacctggtt
     4021 tccctgggaa tcaggggtgc acacacggct gcctacaaga cagcctgaaa tgtgcttggt
     4081 ggctctgcct ttctcttttt caactaaaac tctgtagaag ttgttgttgt tgttgttgtt
     4141 tttctttttc tgtaacagat tctagattcc ctcacaggaa gacaggattc cgtttcttgt
     4201 ccaaacaaag ggaattgatg taaagcaaga acagttagaa catagggaaa atgtattctg
     4261 tatttagtgt agataatacc ttgtaaagga caagtgttac atagtcaagg tagttgcacc
     4321 cacggtttcc agcccatgtt ttactctaac ctggaaggtc aaggagtaaa aggtaagagg
     4381 ctctctgtag agccacactc ctcatggctg aggagggtgc tggggaagga agagacaggc
     4441 acaatatgct aaaagcaatt ttgcagtctc ggtgtagaaa ccattggtgg gaaacactgg
     4501 atcaaatggg aaagggtgtt tgcttgaact cattaattgg tccaaggttc aaatctgtta
     4561 aatgggccct ctcagaatcc cagcaataga aagcactgtt tcccttcagt ggcttcagca
     4621 agtgtgtaga tacattcatg tttacatttc tgtgtgcagt cgctcagcag tgccactggt
     4681 gtttgctgag cctggtctcc gagagagttt ataatgtccg tctagtccta tagcacatgc
     4741 ggatgggtgc agacatcttt aatctctgca gacagtggga aaagcaagtc ctgtgactga
     4801 agcacaacac aggcgtgaag cgacagcaga cgtccgttcc ctgagatctt cctttttttc
     4861 tgcaaatacc tccctgggat aatacaaatc cagacatgtt gatgaatggc tgactgccgc
     4921 ttttattcac acctgttcag ggaaagcaca gaaaatgctc tgtagcacag acattctgga
     4981 cccaagagga gggggaacaa aggaagcctt tttaggaaaa ggaaaacttg cctggagtct
     5041 gtgatgtgaa gaactctcgg tggctggcag ctgacagaag gcaccgtacc tgcacaggag
     5101 cgcctcgggc ttgcttgttg acaatgcaca gaagagactc tagccatctt ccgacaggat
     5161 ggaacagtga gcgagctgtg tgcccggaag ccccatccac ggtcctgcaa ctgagttgta
     5221 ggtttgccca tgagcgatat gcctgaaaca ccactgccgg tcctagtatg ctggggtgaa
     5281 tccgtgtgga gctggaggaa aagccaggag accaactttt gtagaaaaaa cggtatcaat
     5341 aagtgtgtga agccgttgtt ctgggcaagt ggaaagaaat atggaagagt taggattact
     5401 tgggggaggg gaacttgctg aggggtgaac agtccagagg tgatcacttg agaatcagaa
     5461 ctgcagtaat accaccgtaa gcaaatctga atgcatagtt ttaacttaac tggggttgac
     5521 aattcaaata ggtacctccc cccacccccc caaacaaaaa cctgactgag ttgttatgca
     5581 tgtgtcaatc actgggaggt gtgcattctc tagtagtgtt aggctgtttg gttcttttaa
     5641 atgcagccta tttaggtact gtcatgtagt gtggaagatt ttggtgcggc aactctaaag
     5701 aatgacattt ttggggctag ggagcatagg acattaagaa cgggaaagac ccaagtgttg
     5761 aaccaattgt gtttttttgt tgttagttgt tgaatcctga gttgatgcag tcagcattct
     5821 gggcaggcga accacctttg ttcttactgt taagttcttt gtgctgcttc caaagatgat
     5881 ttacaagcag ggatgttcta aatgggtctg taccttaggg tccggggtcc agcccatatc
     5941 ctaggtcaaa gcctacccac ctggctcagc tacctactgc tttaaccagg ctcatcctct
     6001 ctactccgct gtggttgccc tccacggatg tgctctgaga ttctcttgct cagtggcaag
     6061 gtggctgctc tgctttcatt tttaaaaaag cggaagttaa ggtcatcata ctaatactgc
     6121 atcaactcca ggaattaaag gaaagatctt tattgctcaa ccattttctt attggttcct
     6181 actgacatat tcatctcctt tctgtgtcta ctggctgaaa tgtttgtgtt tgttcatctg
     6241 actaacggta tggtttctgt atggttagac ttgtaatgtt ttaaaatgta ttttattact
     6301 ttggactgga tgttcctctc cagcgatacg aggtactttc taagctatta aggaagggtt
     6361 tgaatcccta tgtgagataa gataatggtt gtttaaattt tgcagaggtt tttgttattg
     6421 ttactggttt tgattttggg tttttttttg acctgtgggg atattttgtg tttatgtgtc
     6481 caaaaagtgg ggaggggaat aaattgacat tcttgtgcta aaaaaaa
//
