LOCUS       NM_008032               4486 bp    mRNA    linear   ROD 25-DEC-2023
DEFINITION  Mus musculus AF4/FMR2 family, member 2 (Aff2), mRNA.
ACCESSION   NM_008032
VERSION     NM_008032.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Qi J, Meng C, Mo J, Shou T, Ding L and Zhi T.
  TITLE     CircAFF2 Promotes Neuronal Cell Injury in Intracerebral Hemorrhage
            by Regulating the miR-488/CLSTN3 Axis
  JOURNAL   Neuroscience 535, 75-87 (2023)
   PUBMED   37884088
  REMARK    GeneRIF: CircAFF2 Promotes Neuronal Cell Injury in Intracerebral
            Hemorrhage by Regulating the miR-488/CLSTN3 Axis.
REFERENCE   2  (bases 1 to 4486)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4486)
  AUTHORS   Morimoto K, Numata K, Daitoku Y, Hamada Y, Kobayashi K, Kato K,
            Suzuki H, Ayabe S, Yoshiki A, Takahashi S, Murata K, Mizuno S and
            Sugiyama F.
  TITLE     Reverse genetics reveals single gene of every candidate on Hybrid
            sterility, X Chromosome QTL 2 (Hstx2) are dispensable for
            spermatogenesis
  JOURNAL   Sci Rep 10 (1), 9060 (2020)
   PUBMED   32493902
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4486)
  AUTHORS   Hooper JE, Feng W, Li H, Leach SM, Phang T, Siska C, Jones KL,
            Spritz RA, Hunter LE and Williams T.
  TITLE     Systems biology of facial development: contributions of ectoderm
            and mesenchyme
  JOURNAL   Dev Biol 426 (1), 97-114 (2017)
   PUBMED   28363736
REFERENCE   5  (bases 1 to 4486)
  AUTHORS   Klein AD, Ferreira NS, Ben-Dor S, Duan J, Hardy J, Cox TM, Merrill
            AH Jr and Futerman AH.
  TITLE     Identification of Modifier Genes in a Mouse Model of Gaucher
            Disease
  JOURNAL   Cell Rep 16 (10), 2546-2553 (2016)
   PUBMED   27568557
REFERENCE   6  (bases 1 to 4486)
  AUTHORS   Gu Y and Nelson DL.
  TITLE     FMR2 function: insight from a mouse knockout model
  JOURNAL   Cytogenet Genome Res 100 (1-4), 129-139 (2003)
   PUBMED   14526173
  REMARK    Review article
REFERENCE   7  (bases 1 to 4486)
  AUTHORS   Britanova O, Lukyanov S, Gruss P and Tarabykin V.
  TITLE     The mouse Laf4 gene: exon/intron organization, cDNA sequence,
            alternative splicing, and expression during central nervous system
            development
  JOURNAL   Genomics 80 (1), 31-37 (2002)
   PUBMED   12079280
REFERENCE   8  (bases 1 to 4486)
  AUTHORS   Gu Y, McIlwain KL, Weeber EJ, Yamagata T, Xu B, Antalffy BA, Reyes
            C, Yuva-Paylor L, Armstrong D, Zoghbi H, Sweatt JD, Paylor R and
            Nelson DL.
  TITLE     Impaired conditioned fear and enhanced long-term potentiation in
            Fmr2 knock-out mice
  JOURNAL   J Neurosci 22 (7), 2753-2763 (2002)
   PUBMED   11923441
REFERENCE   9  (bases 1 to 4486)
  AUTHORS   Chakrabarti L, Bristulf J, Foss GS and Davies KE.
  TITLE     Expression of the murine homologue of FMR2 in mouse brain and
            during development
  JOURNAL   Hum Mol Genet 7 (3), 441-448 (1998)
   PUBMED   9467002
REFERENCE   10 (bases 1 to 4486)
  AUTHORS   Chakrabarti L, Knight SJ, Flannery AV and Davies KE.
  TITLE     A candidate gene for mild mental handicap at the FRAXE fragile site
  JOURNAL   Hum Mol Genet 5 (2), 275-282 (1996)
   PUBMED   8824884
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ001549.1 and BX294655.5.
            
            [WARNING] On Jan 17, 2024 this sequence was replaced by
            NM_008032.4.
            
            On Jul 25, 2007 this sequence version replaced NM_008032.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ001549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1753              AJ001549.1         5-1757
            1754-1913           BX294655.5         10973-11132
            1914-2903           BX294655.5         14291-15280
            2904-3245           AJ001549.1         2908-3249
            3246-3547           BX294655.5         29125-29426
            3548-4352           AJ001549.1         3552-4356
            4353-4486           BX294655.5         48133-48266
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 35.53 cM"
     gene            1..4486
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /note="AF4/FMR2 family, member 2"
                     /db_xref="GeneID:14266"
                     /db_xref="MGI:MGI:1202294"
     exon            1..508
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            509..641
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            642..1502
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1547
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1584
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1618
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1715
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1753
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1913
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2903
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            2904..3025
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3026..3245
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3547
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3548..3611
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3612..3748
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3749..3820
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3821..3914
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3915..3967
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            3968..4158
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
     exon            4159..4486
                     /gene="Aff2"
                     /gene_synonym="Fmr2; FMR2P; Ox19; Oxh"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctcggccg ccgccgcctg tgcagccgcc gccgccgctg ctgccgcccc ggctgccgcg
       61 ccgcgccact gccactgcct cgctcgcccc cgcctctgcc gtcgccaccc gccagcagcc
      121 tgccaggcgg gcggcccagg cgaccccagc tctaagcggc cgccaccgca gcccggacgc
      181 gctgggcaag cgggcagccg cggagcgagt ggaccagagc gggaggtcag gctcttgcct
      241 gcccggtgcc atcgcttccg ctgccgccac tgctccggag cgcaggacta ggtaccccgg
      301 gcgcccgccg ctgccgctga tgcggcccca gcacttttaa ccgggtagga gggccagaga
      361 gccgcgccgc cgaccgcagc cagagagccg cgcagctcag agccgcgccg acacgcagcg
      421 agcagggaca gacggccgcc agccgccgcc gccccgccgc tatggatcta ttcgactttt
      481 tcagggattg ggacttggag cagcagtgtc actatgaaca agaccgtagt gcacttaaaa
      541 aaagggaatg ggaacgaagg aatcaagaag ttcagcaaga agaagatctc ttttcttcag
      601 gctttgatct ttttggggag ccctacaagg tagctgaata tacaaacaaa ggggatgccc
      661 ttgccaaccg agtccagaac actcttggaa gttatgatga aatgaaggat ctgctatcta
      721 accattccag tcagaatcat ctggtgggca ttccaaagaa ttctgcaccc caaactccca
      781 tcagcaaaag tgaagcaagc ttttatccag aacaaaaaaa tcgaatgatc ccatctcacc
      841 aggagactac ccactcctca acaccgatgc ctccaccttc agtcgtgata ctgaattcca
      901 ctctaataca cagcaacaga aaatcaaaat ctgagtggcc acgagatagt cataacacta
      961 gccctgcaca agcaagccag accagcagtc aaccaaacaa gatgcagaca tccacacaag
     1021 acccacctca aaccagactg gaagacttct ttgtctaccc tgctgagcaa ccccaaattg
     1081 gtacagttga aaaatctaac ccatcttcaa aggaagaaaa taaccctaat tcaggtggag
     1141 aagatacttt caaagaaatt tttcagtcta attcaccaga agaatctgaa tttacagtgc
     1201 aagcacctgg gtctccccta gttgcctcat ctttattagc tcccagcagt ggcctttcag
     1261 ttccaacatt cccaccaggg ctttactgca aaacaagcat gggacaacaa aaaccaactg
     1321 catatgtaag gcccatggat gggcaggacc aggcaactga catctctcca acactgaagc
     1381 cttccattga atttgagaac agttttggaa acctctcctt tggatcacta ttggatggga
     1441 aacccagtgc agtcagttca aagactaaac tgccaaagtt cacaatcctg caaacaagtg
     1501 aagtaagcct taccagtgat ccaagctgtg ttgaagaaat cttgcgggaa tctcagcatc
     1561 tgactccagg atttacctta caaaagtgga gcgacccaag cagcagagct tccacaaaga
     1621 tgcttgagga tgacttgaag ctgagcagtg atgaagatga ccttgagcct gtgaagacct
     1681 tgaccacaca gtgcacagcc aacgagcttt accaggctgt tgaaaaggca aaacctaaga
     1741 ataatcctgt gaacccactc ttggccacac cacagtctac gcctgcaaca caaaccaatg
     1801 tggggtctgg cagctccagt gagtcagaga gtagctcaga atcggactca gacactgaaa
     1861 gcagcaccac tgacagcgaa tccaatgagg ctcctagagt ggctactcca gagcctgagc
     1921 caccctcaac caacaaatgg cagctagaca aatggctgaa caaagtcacg tcccagaaca
     1981 agtcatttat ttgtggccaa aatgagacac ccacagagac catttctctg cctcctccaa
     2041 taatacaacc ggtggaggtc caggtcaaag tgaaaccaaa ccctagccag gctgtggctg
     2101 tacccaaaga aaggcctctc cttagtctta ttagggaaaa agctcgacca aggcccacac
     2161 agaaaactcc agaaacaaag gccttgaagc ataagctgtc aacatcagtt gacacagttt
     2221 ctcaaaggac aattggaaag aaacagccca aaaaagttga gaaaaacacc agctttgagg
     2281 agtttacctg gcccaaacca aatattacca acagcactcc caaagaaaaa ggaagtgtag
     2341 agcttcctga cccaccacga agccgaaaca aagctactgc ccacaaacca gtgcctagga
     2401 aagagccaag gcctcatgtc cctctggcca ctgagaagaa gaagtataga gggcctggga
     2461 agattgtccc caagtcccgg gaatttattg aaacagattc atctacatct gactccaaca
     2521 cagaccagga agagacccta cagatcaaag tactgccacc ttgcattact tctaaatcca
     2581 aggaaacttc taatgccagc ctgacactta gcaccttgac caatggcaac agcaacaact
     2641 tatccaccag caatgaggag acagcttttt ccccgcctcc tgccatgcaa actgagcttt
     2701 tgtcccctct acgggatcat gaaaatccaa aaaacctctg ggtgaagatt gacctcgact
     2761 tactttctag agtacctggc caaaattcag tcccagtaac acctgcaaag acagactaca
     2821 aggagactgc ctctaaaccc aagcgtcaaa ctgctgccac agctgtggaa aaaccagccc
     2881 ctaagggcaa acgtaagcac aagccagcag aaactgcaga gaaaatccct gagaagaagc
     2941 agcgcctgga ggacaacact actatctgcc tgcttccccc ttgcatctca ccagccccgc
     3001 cccacaagcc tcccagcact agagaaaatt catccaggag agcaaacagg aaaaaagaag
     3061 aaaagctgtt ccctcctgca ctttccccac tggcagagga tcctccacgt cgcagaaatg
     3121 tcagtggcaa caatgggcat ttcggtcagg acaaaaacat ttccatggct ggacaaatca
     3181 cctctagcaa acctaaaaga agtgaaggca aattctgtgc tactttcaag gggatatcta
     3241 taaatgaggg agatgctcca aaaaaggctg cctctgccac cgttactgtc gccaatatgg
     3301 ctcttgccac tgctactgcc actgccactg ttcctgccat tgtcactgcc actgtcacag
     3361 ctactgccac caccactgct acagccacta ccacaaccac taccactact atttctagca
     3421 tcacccctac aatcacttct ggccttatgg atagcagtca cctggagatg acatcctggg
     3481 cagccctgcc ccttctgtcc agcagtagtg ccaatgtccg gagacccaag ctcacatttg
     3541 atgactctgt tcacaatgct gatttttaca tgcaagaggc taagaagctg aaacacaaag
     3601 ctgatgcact gtttgagaaa tttggcaaag ctgtgaatta tgcagatgca gccttgtcct
     3661 tcactgaatg tggcaatgcc atggaacgtg atcctctgga agcgaagtcc ccatatacca
     3721 tgtattctga gactgtggag ctcctcaggt atgcaatgag actgaagaac tttgcaagcc
     3781 ccttggcttc tgatggggat aaaaagctag ccgtattatg ctaccgatgc ttgtcacttc
     3841 tctatttgag gatgtttaaa ctgaagaagg accatgctat gaagtactcc agatcactga
     3901 tggaatattt taagcaaaat gcttcaaaag ttactcagat accatctcct tgggtaggca
     3961 atggaaagaa tactccatcc ccagtgtctc tcaacaatgt ctctcccatc aactcagtgg
     4021 ggaattgtaa caatggccct gtcacaattc cccagcgcat ccaccatatg gctgctagcc
     4081 atgtgaatat taccagtaat gtgcttcggg gctatgaaca ctgggatatg gctgacaaac
     4141 tgacaagaga caataaagaa ttctttggtg atctggatac actgatgggg cctctgaccc
     4201 agcacagcag catgaccaat cttgtccgct atgttcgcca gggactgtgt tggctacgca
     4261 tcgatgctca tttgttgtag tgggcactct gccatctctc gcatcagcac tcatccttta
     4321 ccagtgcctt aatggtcact ggtggaactc cactcatttg ggaaagttct ctttcattat
     4381 gtttgttttt gtgcattttt gatatctgtg aaaaactgaa gtcattgtaa gtggacacta
     4441 caacttgaga gaagtgtatg ttttattttt taatatttga tatgca
//
