LOCUS       NM_178928               3403 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus actin filament associated protein 1-like 1 (Afap1l1),
            mRNA.
ACCESSION   NM_178928
VERSION     NM_178928.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3403)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3403)
  AUTHORS   Ahuja,N., Hiltabidle,M.S., Rajasekhar,H., Voss,S., Lu,S.Z.,
            Barlow,H.R., Cowdin,M.A., Daniel,E., Vaddaraju,V., Anandakumar,T.,
            Black,E., Cleaver,O. and Maynard,C.
  TITLE     Endothelial Cyp26b1 restrains murine heart valve growth during
            development
  JOURNAL   Dev Biol 486, 81-95 (2022)
   PUBMED   35364055
REFERENCE   3  (bases 1 to 3403)
  AUTHORS   Samuels,A.L., Klinken,S.P. and Ingley,E.
  TITLE     Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein
            that influences erythropoietin-induced differentiation
  JOURNAL   Blood 113 (16), 3845-3856 (2009)
   PUBMED   19064729
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC125157.4.
            
            On Nov 17, 2006 this sequence version replaced NM_178928.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035227.1, BC138923.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                AC125157.4         29905-29991
            88-216              AC125157.4         57839-57967
            217-300             AC125157.4         58832-58915
            301-395             AC125157.4         59633-59727
            396-507             AC125157.4         60893-61004
            508-606             AC125157.4         63960-64058
            607-818             AC125157.4         64690-64901
            819-998             AC125157.4         67692-67871
            999-1091            AC125157.4         69697-69789
            1092-1185           AC125157.4         72807-72900
            1186-1338           AC125157.4         73137-73289
            1339-1550           AC125157.4         74726-74937
            1551-1696           AC125157.4         77298-77443
            1697-1769           AC125157.4         77811-77883
            1770-1881           AC125157.4         78960-79071
            1882-2046           AC125157.4         79620-79784
            2047-2225           AC125157.4         80821-80999
            2226-2354           AC125157.4         82735-82863
            2355-3403           AC125157.4         85257-86305
FEATURES             Location/Qualifiers
     source          1..3403
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.71 cM"
     gene            1..3403
                     /gene="Afap1l1"
                     /note="actin filament associated protein 1-like 1"
                     /db_xref="GeneID:106877"
                     /db_xref="MGI:MGI:2147199"
     exon            1..87
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..2378
                     /gene="Afap1l1"
                     /note="AFAP1-like protein 1"
                     /codon_start=1
                     /product="actin filament-associated protein 1-like 1"
                     /protein_id="NP_849259.2"
                     /db_xref="CCDS:CCDS50303.1"
                     /db_xref="GeneID:106877"
                     /db_xref="MGI:MGI:2147199"
                     /translation="MDRSRVLEQLIPELTGLLSLLDHEYLSDSTLEKKMAVASLLQSL
                     QPLPAKEVSFLYVNTADLHSGPSFVESLFEEFDCDLGDLRDMSDDGEPSKGASPEPTK
                     SPSLRSAAADVPPPLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPAQSIVDGYYE
                     DADNSYPTTRMNGELKNSYNDSDAMSSSYESYDEEEEEEKGRQPKHQWPSEEASMHLV
                     RDCRICAFLLRKKRFGQWAKQLTVIKEEQLLCYKSSKDRQPHLRLALDVCTVIYVPKD
                     SRHKRHELRFSQGATEVLVLALQSREQAEEWLKVIREVSRPIVGAEGLEVPRSPVILC
                     KADQDKRLSQEKQNSDSDSLGMNDSGSTLGRREACEHGKGKKNSLAELKGSMSRAAGR
                     KITRIISFSKKKALSEDLQTFSSEDEVPCCGYLNVLVNQGWKERWCRLRCNTLYFHKD
                     RTDLHTHVNSIALRGCEVAPGFGPRHPFAFRILRNRQEVAILEASCSEDMGRWLGLLL
                     VEMGSKVTPEALHYDYVDVETLTSIVSAGRNSFLYAQSCQDQWPEPRIYDEVPYEKVQ
                     DEEPQRPTGAQVKRHASSCSEKSHRADPQVKVKRHASSANQYKYGKNRAEEDARRYLV
                     EKERLEKEKETIRTELTALRQEKKELKEAIRNNPGAKSKALEEAVATLEAQCRAKEEQ
                     RIDLELKLVAVKERLQQSLAGGPALGLSVSNKNKSQDTTNKPQSNAPEQSLPVNCVSE
                     LRKRSPSIVTSNQGRVLQKAKEWEMKKT"
     exon            88..216
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            217..300
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            301..395
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            396..507
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            508..606
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            607..818
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            819..998
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1091
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1185
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1338
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1550
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1696
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1769
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1881
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2046
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2047..2225
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2226..2354
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..3403
                     /gene="Afap1l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagagcgcac gccgcctggt gcggcagccg ctgcgccctg ggctgagtgc tccaggattc
       61 acgccggagc catggaccga agcagggtgc tggaacagct aatcccagag ctcaccggac
      121 tcctcagcct cctggaccat gagtatctca gcgacagcac cctggagaag aagatggctg
      181 tggcctccct cctgcagagc ctgcagcccc tcccagcaaa ggaagtctct ttcctgtatg
      241 tgaacactgc agacctgcac tcggggccca gctttgtgga gtctctcttt gaagaattcg
      301 actgtgacct gggtgacctt cgggatatgt cggacgatgg ggaacccagc aaaggagcca
      361 gccctgagcc aaccaagagc ccatctctga gaagcgcagc tgctgatgtg cctccaccct
      421 tgcccaacaa gcccccgccc gaggactact atgaagaagc ccttcccctg gggcccggca
      481 agtcccccga gtatatcagc tctcacaatg gctgcagccc tgcacagtcg attgtggacg
      541 gttactacga ggacgcagac aacagctacc ccaccacaag gatgaatgga gaactgaaga
      601 actcctacaa tgactctgac gccatgagta gctcctatga atcctacgac gaggaggagg
      661 aggaagagaa ggggcggcag cccaagcacc agtggccctc ggaagaggcc tccatgcacc
      721 tggttaggga ctgcaggata tgtgccttcc tgcttcggaa aaagcgcttc gggcagtggg
      781 ccaagcagct gacggtcatc aaggaggagc agctactgtg ttacaaaagc tccaaggacc
      841 gacagccaca cctgaggctg gcgctagacg tctgcactgt catctatgtg cccaaggaca
      901 gcaggcacaa gcggcacgag ctgcgcttct cccagggggc cacagaggtg ttagtgctgg
      961 ctctgcagag cagggagcag gccgaggagt ggctgaaggt catccgagag gtcagccggc
     1021 ccattgtggg agcagagggc ttggaggtcc ccagatcccc agtcatccta tgcaaggcgg
     1081 atcaggacaa gaggttgtcc caagagaaac agaactcaga ctccgacagc ctgggcatga
     1141 atgacagtgg ttccactctc ggccgtcgag aagcctgtga acatggcaaa gggaagaaga
     1201 acagcctggc tgagcttaag ggctccatga gcagggctgc cggccgcaag atcacgcgca
     1261 tcatcagttt ctccaagaag aaggcgctgt ccgaggacct gcagacattc tccagtgagg
     1321 acgaggttcc atgctgtggc tacctgaatg tgctggtaaa ccaaggctgg aaggaacggt
     1381 ggtgtcgcct caggtgcaac actctctatt tccacaaaga ccgcacagac ctgcacaccc
     1441 acgtgaattc catagccctc aggggctgcg aggtagcccc aggctttgga cccaggcacc
     1501 cctttgcctt caggatcctg cgcaatcgac aggaggtggc catcctggag gcaagctgct
     1561 cagaggacat gggccgctgg ctcggtctgc tgctagtgga gatgggctcc aaagtcaccc
     1621 cagaggcact gcactatgac tacgtcgacg tggagacctt aaccagcatc gtcagtgctg
     1681 ggcgcaactc cttcctgtat gcacagtcct gccaggatca gtggcctgag ccccgcatct
     1741 acgatgaggt tccttatgaa aaggtgcagg atgaggagcc ccagcgcccc accggggctc
     1801 aggtgaagcg ccacgcctcc tcctgcagtg agaagtccca ccgtgcggac ccgcaggtca
     1861 aagtcaagcg ccacgcctcc agtgccaatc aatacaagta cggcaagaac cgggcggagg
     1921 aggatgcccg aaggtacctg gtagaaaaag agaggctgga gaaagagaag gaaacgattc
     1981 ggacagaact gacggccttg cgacaggaga agaaagagct gaaggaagcc attcggaaca
     2041 acccaggagc aaagtcgaag gccttggaag aggccgtggc cactctggaa gctcaatgcc
     2101 gtgccaagga agagcagagg atcgacctgg agctcaagct ggtagctgtg aaggagcgct
     2161 tgcagcagtc cctggccggg ggtccggccc tcggtctgtc cgtgagcaac aagaacaaga
     2221 gccaagacac tacaaataaa ccccaaagca atgccccaga gcaatctctc cctgtcaact
     2281 gtgtttctga actgagaaag aggagtccat ccattgtgac ctccaaccaa gggagggtgc
     2341 tacagaaggc caaggaatgg gaaatgaaga agacctagag agggtgagaa gtccaccctg
     2401 aagcagcatc agcttgtccg ttctaaggag ggaatgcttt cttcgccaag acatcaggaa
     2461 aagactgggg cacccaaaag accagcttga ctgtccgcat ggttttaagg attgtgggaa
     2521 gggaggcgtg gaagcgtcct tctggctaga caaagggtgg agctgggagt gtccggagac
     2581 agaatcgtcc acagttgtaa aggttttatt agttatcttt gccttctgat gcaatgaacg
     2641 cacgtaagcc attccatcct ttccttggcc tctcagtccc atccttagag caaaggaagc
     2701 cagtgttgaa gtgctgctag tgttgtaata aaaaagaaaa ccactccatc acctgatcac
     2761 acttaggcag gctgattcct gttggccatt acaggcaacc ctggacaggg ttaatggact
     2821 ggaaaatcaa tgtattcctg cctgctcaac agtgaacaaa agctattgag aatgtaaaaa
     2881 tcccagtttt ctgttttaga gccaggcagc tgctagaacc ttccatgttt gagcatcttt
     2941 aaatcagatt gtctgagaat tcagagggta aagagggctg atcagctggc acattttaag
     3001 cacagtggct ggaagtatgg agtgctaatg ctgacactgt tgtatgcatt ggaaggtgga
     3061 gtcctttgct gtcagtcaag tgcttaccta cttaatgtga cactgaagct cctgggactg
     3121 tggttgaagc tctctggcct gaggaagtct tcatcttgta ctaggaagca cacaagcctg
     3181 tttccttatc cgctacacag tgagactatt aaggaaaact aacaggatgg tggctcatgt
     3241 ctaccacaag ggtgctaagc cttttccaaa cacttgatat ttctatagga ccttaggtcc
     3301 taagcaacct cttttctatg ccattcaatg actgtctcaa cactgggctt tgaagtctgt
     3361 tttaacatac acatctccaa taaagatgaa ctgtcgaact ctg
//
