LOCUS       NM_025510               1492 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ADP-ribose/CDP-alcohol diphosphatase, manganese
            dependent (Adprm), mRNA.
ACCESSION   NM_025510
VERSION     NM_025510.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1492)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1492)
  AUTHORS   Canales,J., Fernandez,A., Ribeiro,J.M., Cabezas,A., Rodrigues,J.R.,
            Cameselle,J.C. and Costas,M.J.
  TITLE     Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel
            metallophosphoesterase family preferentially expressed in rodent
            immune cells
  JOURNAL   Biochem J 413 (1), 103-113 (2008)
   PUBMED   18352857
  REMARK    GeneRIF: The structure and function of Mn2+-dependent
            ADP-ribose/CDP-alcohol pyrophosphatase in immune tissues are
            reported.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY118851.1 and AK145941.1.
            
            On Nov 15, 2007 this sequence version replaced NM_025510.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145941.1, BC004029.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                BY118851.1         1-57
            58-1492             AK145941.1         1-1435
FEATURES             Location/Qualifiers
     source          1..1492
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 40.59 cM"
     gene            1..1492
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /note="ADP-ribose/CDP-alcohol diphosphatase, manganese
                     dependent"
                     /db_xref="GeneID:66358"
                     /db_xref="MGI:MGI:1913608"
     exon            1..84
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /inference="alignment:Splign:2.1.0"
     exon            85..182
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /inference="alignment:Splign:2.1.0"
     exon            183..809
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..1231
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /EC_number="3.6.1.13"
                     /EC_number="3.6.1.16"
                     /EC_number="3.6.1.53"
                     /note="ADP-ribose/CDP-alcohol pyrophosphatase;
                     ADPRibase-Mn; CDP-choline phosphohydrolase"
                     /codon_start=1
                     /product="manganese-dependent ADP-ribose/CDP-alcohol
                     diphosphatase"
                     /protein_id="NP_079786.2"
                     /db_xref="CCDS:CCDS48820.1"
                     /db_xref="GeneID:66358"
                     /db_xref="MGI:MGI:1913608"
                     /translation="MADKLVPSSPADASEPLFSFGVIADIQYADLEDGYNYQRSRRRY
                     YRHSLIHLQGAIEDWNKESSMPCCVLQLGDIIDGYNAQYKVSEKSLELVMNTFQMLKV
                     PVHHTWGNHEFYNFSRDYLASSKLNSKFLEDQIAQHPETTPSENYYAYHFVPFPKFRF
                     ILLDSYDLSVLGIDPSSPKYEQCMKMLREHNPNVELNSPQGLSEPQYVQFNGGFSQEQ
                     LNWLNEVLTFSDTNQEKVVIVSHLPIYPEASDSVCLAWNYVDALSIIWSHKCVVCFLA
                     GHTHDGGYSEDPFGVHHVNLEGVIETAPDSQAFGTVHVFPDKMLLKGRGRVPDRIMNY
                     KREEAL"
     exon            810..926
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1492
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1299..1304
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /note="hexamer: CATAAA"
     polyA_site      1318
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /note="major polyA site"
     regulatory      1453..1458
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
                     /note="hexamer: AATAAA"
     polyA_site      1474
                     /gene="Adprm"
                     /gene_synonym="2310004I24Rik; MDS006"
ORIGIN      
        1 gaggccgctc tttcctcttg gctcgttggt gacgctgttt gccctctggt tgtggaggag
       61 tcccgggtcc ggcggctgat agcggggatc ccagcattgc ttcagggatt gttgcattgg
      121 agcatgatac tgttcttctc cgtgcttggc ttttttgatc tatcgggctg ctctctaaca
      181 cccttattta gaagtctgct tggaggttat ggctgataag ctggtgccca gttccccggc
      241 tgatgcttca gagccactgt tttccttcgg agttatagca gatattcaat acgcagattt
      301 agaagatgga tacaattatc aaagaagccg gcggaggtac taccgacaca gtcttattca
      361 cttacagggt gccatcgaag actggaataa agaaagcagc atgccctgtt gtgtcctgca
      421 gcttggagac atcatcgatg gctacaatgc acagtataaa gtatcagaaa agtctctaga
      481 acttgtcatg aacacatttc agatgcttaa agttccagtt caccacacgt gggggaacca
      541 tgagttctat aacttcagca gagactactt agcaagctct aaactgaaca gcaagtttct
      601 agaagaccag attgcacagc atcctgagac cacgccatca gagaactatt acgcttatca
      661 ctttgtacca ttccctaagt tccggttcat tttactcgat tcttatgacc tgagtgtctt
      721 gggcatagac ccatcttctc caaaatatga gcagtgtatg aagatgctga gggagcacaa
      781 cccaaatgtg gagttgaata gtccccaagg actttctgag ccccagtatg tccagtttaa
      841 cggaggattc agccaagaac agctgaactg gctgaatgaa gttcttacat tctctgacac
      901 gaaccaggag aaggtggtga ttgtgagcca tcttcctatt tacccagagg cctctgacag
      961 cgtgtgcctg gcttggaact acgtggatgc tctgtcaatc atatggtctc acaagtgtgt
     1021 ggtgtgtttc cttgctggtc acacacatga cggtggctac tctgaagatc ctttcggcgt
     1081 gcaccatgtc aaccttgaag gagttattga aacagctccg gacagccagg cctttggcac
     1141 agttcatgtc ttccctgaca aaatgctgct gaaagggaga ggcagagttc cagacagaat
     1201 tatgaattat aaaagggaag aagctttgtg attttcgcct cattatcttg tctgctttgt
     1261 agaaagtgaa cgatactgtt ttatgtttta ttacattcca taaaaagtta aattctcagt
     1321 tgtactctta agtattctgt ttgtgtacaa aatgtatttg caccttgagt atgtgtgagt
     1381 gaagataaaa ctcagaagtg ttatttctgg ataatatatc caggtactga aagctagtac
     1441 tgaaaatatt aaaataaacc aggaaggaga ctcatgtggg catatactcc tg
//
