LOCUS       NM_172825               2701 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus adhesion G protein-coupled receptor G7 (Adgrg7), mRNA.
ACCESSION   NM_172825 XM_156286
VERSION     NM_172825.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2701)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2701)
  AUTHORS   Weng,Z., Situ,C., Lin,L., Wu,Z., Zhu,J. and Zhang,R.
  TITLE     Structure of BAI1/ELMO2 complex reveals an action mechanism of
            adhesion GPCRs via ELMO family scaffolds
  JOURNAL   Nat Commun 10 (1), 51 (2019)
   PUBMED   30604775
  REMARK    GeneRIF: Based on the crystal structures of ELMO2-RAE and its
            complex with BAI1 study identified aGPCR-GPR128 as another upstream
            receptor for the ELMO family scaffolds.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2701)
  AUTHORS   Hamann,J., Aust,G., Arac,D., Engel,F.B., Formstone,C.,
            Fredriksson,R., Hall,R.A., Harty,B.L., Kirchhoff,C., Knapp,B.,
            Krishnan,A., Liebscher,I., Lin,H.H., Martinelli,D.C., Monk,K.R.,
            Peeters,M.C., Piao,X., Promel,S., Schoneberg,T., Schwartz,T.W.,
            Singer,K., Stacey,M., Ushkaryov,Y.A., Vallon,M., Wolfrum,U.,
            Wright,M.W., Xu,L., Langenhan,T. and Schioth,H.B.
  TITLE     International Union of Basic and Clinical Pharmacology. XCIV.
            Adhesion G protein-coupled receptors
  JOURNAL   Pharmacol Rev 67 (2), 338-367 (2015)
   PUBMED   25713288
  REMARK    Review article
REFERENCE   4  (bases 1 to 2701)
  AUTHORS   Ni,Y.Y., Chen,Y., Lu,S.Y., Sun,B.Y., Wang,F., Wu,X.L., Dang,S.Y.,
            Zhang,G.H., Zhang,H.X., Kuang,Y., Fei,J., Gu,M.M., Rong,W.F. and
            Wang,Z.G.
  TITLE     Deletion of Gpr128 results in weight loss and increased intestinal
            contraction frequency
  JOURNAL   World J Gastroenterol 20 (2), 498-508 (2014)
   PUBMED   24574718
  REMARK    GeneRIF: Generated a mouse model with a targeted deletion of Gpr128
            and found reduced body weight and increased intestinal contraction
            frequency in this animal model.
REFERENCE   5  (bases 1 to 2701)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 2701)
  AUTHORS   Bjarnadottir,T.K., Fredriksson,R., Hoglund,P.J., Gloriam,D.E.,
            Lagerstrom,M.C. and Schioth,H.B.
  TITLE     The human and mouse repertoire of the adhesion family of
            G-protein-coupled receptors
  JOURNAL   Genomics 84 (1), 23-33 (2004)
   PUBMED   15203201
REFERENCE   7  (bases 1 to 2701)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025158.5.
            
            On Aug 8, 2009 this sequence version replaced NM_172825.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033593.1, BC132302.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-312               CT025158.5         172519-172830       c
            313-426             CT025158.5         155554-155667       c
            427-531             CT025158.5         154081-154185       c
            532-644             CT025158.5         150377-150489       c
            645-791             CT025158.5         147185-147331       c
            792-892             CT025158.5         144790-144890       c
            893-1023            CT025158.5         139032-139162       c
            1024-1131           CT025158.5         138812-138919       c
            1132-1298           CT025158.5         129323-129489       c
            1299-1454           CT025158.5         127379-127534       c
            1455-1567           CT025158.5         124893-125005       c
            1568-1911           CT025158.5         119231-119574       c
            1912-2008           CT025158.5         117055-117151       c
            2009-2164           CT025158.5         109738-109893       c
            2165-2321           CT025158.5         107196-107352       c
            2322-2701           CT025158.5         101581-101960       c
FEATURES             Location/Qualifiers
     source          1..2701
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 34.22 cM"
     gene            1..2701
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /note="adhesion G protein-coupled receptor G7"
                     /db_xref="GeneID:239853"
                     /db_xref="MGI:MGI:2441732"
     exon            1..312
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     CDS             198..2555
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /note="probable G-protein coupled receptor 128; G
                     protein-coupled receptor 128; G protein coupled receptor
                     Gpr128"
                     /codon_start=1
                     /product="adhesion G-protein coupled receptor G7
                     precursor"
                     /protein_id="NP_766413.2"
                     /db_xref="CCDS:CCDS28225.1"
                     /db_xref="GeneID:239853"
                     /db_xref="MGI:MGI:2441732"
                     /translation="MRSCRSCNVRVLVAIVCGLLTGIVLGLGIWRMVIRINRGIFVPV
                     PSIPVQFCRNGGTWQNGRCICTEEWKGLRCTIANFCENSTDGEFTFGSIPVGRYGPSL
                     QTCEPGTLNAGSPKATRLCNVSEFGNIELQNVTKGSCNINLQTLEIQINNQTASAENI
                     SREAQVLTADASKLTAQNITSATTVVGQIFGKANNESQAKKTAIATVSQILDASEDVF
                     QKAAEMDNSKSFSNLIKQMENYSYSQGDQTVVEPNIAIQSVTRDDNSGPSVLFSVQKG
                     SSNSLVSGRILINKTANGLNPDGQTELQILLNTGENRKSCGFMVYQNHKLFQSKTFTA
                     TSDFSQKIISSKINESEQQRQNKVSVEMVFNPTYDKRELRLHSYACVYWNFLINDWDT
                     QGCQKTGNTTEFLRCNCSHTTNFAVLMSFKKDYKYPKSLDILSNIGCALSIAGLALTI
                     LFQILTRKIRKTSVTWVLVSLCSSMLIFNLLFVFGIENSNKNLKTSDSDINVKPENNK
                     IPESDTIETPNPSCTAIAALLHYFLLVTFTWNGLSATQLYFLLIRTMKPLPRHFIIFI
                     SLVGWGVPAIIVGVTIGSIYALSGNKRYWELDYRQEEICWLAVPKDNDYARSPLLWSF
                     IIPVTIILITNITIFVIITVKVLWKNNQNLTSTKKVSSLKKVFSTLSIAVVFGVTWIL
                     AYAMLISNDDIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKILKSLSSSFDR
                     TKPMPSITPLKLRVRMYNMLRSLPSLNERFRLLEPSGMTEETSLS"
     exon            313..426
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            427..531
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            532..644
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            645..791
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            792..892
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1023
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1131
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1298
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1454
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1567
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1911
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2008
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            2009..2164
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2321
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
     exon            2322..2701
                     /gene="Adgrg7"
                     /gene_synonym="9130020O16Rik; Gpr128"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcttgatct ccctcggtga agaatgagca tactgcacgc agaaacccac cttctctttg
       61 gtgattccaa cttcattact ctgaattaac ttcaaaactc ttaaaccatg agatcacctg
      121 tcagacagac cactgaaggg aagaattctt ttcatgtttt ataactatct ctgttcgtgc
      181 agtgttttgg cttcaccatg cgttcctgtc gttcctgcaa tgtccgggta ctggtggcta
      241 ttgtgtgtgg gctactgaca ggcattgttc tgggactcgg catctggagg atggtcataa
      301 ggatcaacag agggatattt gttcctgtgc caagtatccc tgtacagttc tgcaggaatg
      361 gcggaacctg gcaaaatggc agatgcattt gtacagaaga gtggaaaggg ctgcgttgta
      421 caattgctaa tttctgtgaa aatagtaccg acggtgaatt cacctttggc agtatcccag
      481 tgggcagata tggaccctct ttgcaaacat gtgaaccggg caccctcaat gcgggcagtc
      541 ctaaagcaac tcggctgtgc aatgtttctg agtttggaaa catagaacta caaaatgtaa
      601 ccaaaggaag ttgtaatata aatctacaga ccctggagat acagataaac aaccaaacag
      661 caagtgctga gaatatttct agagaagccc aggttttaac agcagatgcc agtaaactga
      721 ctgctcagaa tatcacttct gctactacag tggttggaca gatcttcggt aaagccaaca
      781 atgaaagcca ggcaaaaaaa actgctatag ccacagtgag tcagattttg gatgccagtg
      841 aagatgtttt tcaaaaagct gctgagatgg acaacagcaa atcctttagc aatcttatca
      901 agcaaatgga gaattactcc tattctcaag gtgatcagac agtggtggaa cccaatatag
      961 caatccagtc cgtcactcga gacgacaatt cagggccaag tgttctcttc tccgtacaga
     1021 aaggatctag taattctctg gtttctggta gaatattgat taacaaaact gcaaatggac
     1081 tcaacccaga cggacagacc gaacttcaga tcttacttaa tactggggaa aatagaaaat
     1141 catgtggttt tatggtgtat caaaaccaca aacttttcca atcaaaaact ttcactgcta
     1201 catcagattt tagtcaaaaa attatctcca gcaaaataaa tgaaagtgaa caacaacgcc
     1261 aaaataaagt ttctgtggaa atggtattta atcctacgta tgacaaaaga gaactccggc
     1321 ttcactccta tgcttgtgtc tactggaatt ttttaataaa tgactgggac acacaaggct
     1381 gccaaaaaac cgggaacacc acagaattcc tccgttgcaa ctgcagccac acgaccaatt
     1441 tcgctgtatt gatgagtttc aaaaaggatt acaagtatcc caaatctcta gacatattat
     1501 ccaacatcgg ctgtgcctta tccattgctg gtctggctct cacaatctta ttccagattc
     1561 tcaccaggaa aatcagaaaa acctcagtaa cctgggtgtt ggtcagtttg tgttcatcaa
     1621 tgttgatttt taacctcctc tttgtgtttg gaattgaaaa ctccaataag aacctaaaga
     1681 caagtgatag tgacatcaat gttaaacctg aaaataacaa aataccagaa agtgacacca
     1741 ttgaaacccc gaatccctca tgcacagcca ttgctgcctt gctccactac tttctgctgg
     1801 tgacattcac ctggaatgga ctcagtgcta cacaactcta cttccttctg ataagaacca
     1861 tgaagcctct ccctcggcat ttcattatct tcatctcatt agttggatgg ggagttccag
     1921 caataatagt aggtgtgacg attgggagta tttatgccct gagtgggaac aagaggtact
     1981 gggagttaga ctatcggcaa gaggaaattt gctggctggc cgttcccaag gacaatgatt
     2041 atgcaagaag tccacttttg tggtcgttca tcatacctgt aaccattatc ctcatcacca
     2101 acattactat atttgtcata atcacagtca aagtgttgtg gaagaacaac cagaacctga
     2161 caagcacaaa aaaagtttca tccctaaaga aggttttcag cacactatct atcgctgttg
     2221 tttttggagt tacctggatc ttggcatatg ctatgctaat tagtaacgat gacatcagga
     2281 ttgttttcag ctacatattc tgtcttttca acaccactca gggattgcaa atattcattc
     2341 tctacactgt tcgaacaaaa gtatttcaga gtgaagcttc caaaatactg aagtcactgt
     2401 catcatcctt tgatagaacg aagccaatgc cttcgataac cccgctgaaa ctgcgtgtaa
     2461 ggatgtacaa tatgctcagg tccctaccat ccctaaatga acgctttagg ctgctggagc
     2521 catctggaat gactgaggaa acatcattgt cttgaaagtg accaagcaaa atcaagtgcc
     2581 taacaagagt tacccatgat ggtcttttga ttccaactca taagaattgt atctgtttat
     2641 gttattctct aagtgtccta caagatcttc ctgaatgcat gttaaagctg tttattatca
     2701 c
//
