LOCUS       NM_001347486            5067 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus adhesion G protein-coupled receptor D1 (Adgrd1),
            transcript variant 2, mRNA.
ACCESSION   NM_001347486 XM_006504307
VERSION     NM_001347486.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5067)
  AUTHORS   Bianchi,E., Sun,Y., Almansa-Ordonez,A., Woods,M., Goulding,D.,
            Martinez-Martin,N. and Wright,G.J.
  TITLE     Control of oviductal fluid flow by the G-protein coupled receptor
            Adgrd1 is essential for murine embryo transit
  JOURNAL   Nat Commun 12 (1), 1251 (2021)
   PUBMED   33623007
  REMARK    GeneRIF: Control of oviductal fluid flow by the G-protein coupled
            receptor Adgrd1 is essential for murine embryo transit.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5067)
  AUTHORS   Yorgan,T.A., Peters,S., Amling,M. and Schinke,T.
  TITLE     Osteoblast-specific expression of Panx3 is dispensable for
            postnatal bone remodeling
  JOURNAL   Bone 127, 155-163 (2019)
   PUBMED   31202927
REFERENCE   4  (bases 1 to 5067)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5067)
  AUTHORS   Hamann,J., Aust,G., Arac,D., Engel,F.B., Formstone,C.,
            Fredriksson,R., Hall,R.A., Harty,B.L., Kirchhoff,C., Knapp,B.,
            Krishnan,A., Liebscher,I., Lin,H.H., Martinelli,D.C., Monk,K.R.,
            Peeters,M.C., Piao,X., Promel,S., Schoneberg,T., Schwartz,T.W.,
            Singer,K., Stacey,M., Ushkaryov,Y.A., Vallon,M., Wolfrum,U.,
            Wright,M.W., Xu,L., Langenhan,T. and Schioth,H.B.
  TITLE     International Union of Basic and Clinical Pharmacology. XCIV.
            Adhesion G protein-coupled receptors
  JOURNAL   Pharmacol Rev 67 (2), 338-367 (2015)
   PUBMED   25713288
  REMARK    Review article
REFERENCE   6  (bases 1 to 5067)
  AUTHORS   Bohnekamp,J. and Schoneberg,T.
  TITLE     Cell adhesion receptor GPR133 couples to Gs protein
  JOURNAL   J Biol Chem 286 (49), 41912-41916 (2011)
   PUBMED   22025619
  REMARK    GeneRIF: Cell adhesion receptor GPR133 couples to Gs protein
REFERENCE   7  (bases 1 to 5067)
  AUTHORS   Kim,W., Matsui,T., Yamao,M., Ishibashi,M., Tamada,K., Takumi,T.,
            Kohno,K., Oba,S., Ishii,S., Sakumura,Y. and Bessho,Y.
  TITLE     The period of the somite segmentation clock is sensitive to Notch
            activity
  JOURNAL   Mol Biol Cell 22 (18), 3541-3549 (2011)
   PUBMED   21795391
REFERENCE   8  (bases 1 to 5067)
  AUTHORS   Bjarnadottir,T.K., Fredriksson,R., Hoglund,P.J., Gloriam,D.E.,
            Lagerstrom,M.C. and Schioth,H.B.
  TITLE     The human and mouse repertoire of the adhesion family of
            G-protein-coupled receptors
  JOURNAL   Genomics 84 (1), 23-33 (2004)
   PUBMED   15203201
REFERENCE   9  (bases 1 to 5067)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158913.4 and AC115899.12.
            
            On Nov 29, 2016 this sequence version replaced XM_006504307.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon compared to variant 1. The resulting isoform (2) has the same
            N- and C-termini but is shorter compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158001.1, SRR10223969.6126.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-477               AC158913.4         63434-63910
            478-514             AC158913.4         63993-64029
            515-598             AC158913.4         76262-76345
            599-721             AC158913.4         81739-81861
            722-901             AC158913.4         89095-89274
            902-1156            AC158913.4         95538-95792
            1157-1212           AC158913.4         98261-98316
            1213-1368           AC158913.4         99396-99551
            1369-1428           AC158913.4         103619-103678
            1429-1546           AC158913.4         106272-106389
            1547-1657           AC158913.4         107418-107528
            1658-1733           AC158913.4         109144-109219
            1734-1875           AC158913.4         110651-110792
            1876-1949           AC158913.4         129279-129352
            1950-2073           AC158913.4         138490-138613
            2074-2177           AC158913.4         144733-144836
            2178-2289           AC158913.4         145853-145964
            2290-2443           AC158913.4         146227-146380
            2444-2510           AC115899.12        87382-87448
            2511-2577           AC115899.12        88689-88755
            2578-2669           AC115899.12        97674-97765
            2670-2796           AC115899.12        99736-99862
            2797-2838           AC115899.12        100188-100229
            2839-2931           AC115899.12        100512-100604
            2932-5067           AC115899.12        101520-103655
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 67.99 cM"
     gene            1..5067
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /note="adhesion G protein-coupled receptor D1"
                     /db_xref="GeneID:243277"
                     /db_xref="MGI:MGI:3041203"
     exon            1..477
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            478..514
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            515..598
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            599..721
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            722..901
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1156
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1212
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1368
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1428
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1546
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..1657
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1733
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1875
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1876..1949
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2073
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2177
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2289
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2443
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2444..2510
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2577
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2578..2669
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2670..2796
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2797..2838
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2839..2931
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..5067
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5046..5051
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /note="hexamer: AATAAA"
     polyA_site      5067
                     /gene="Adgrd1"
                     /gene_synonym="E230012M21Rik; Gpr133"
                     /note="major polyA site"
ORIGIN      
        1 agtacacaca tcactaagct ccaagctacg ggctgagctc tgagctccga cttgagactt
       61 gagacaggag gcaagtgccc accagtccca gacccaggac acagactcct aagcctgtag
      121 gcacccagag gttctggcct gcccatcagc agccagagcc ttggggactc tggtggagct
      181 gagaaggagt gcttatccaa ctcagcactg cctctagcct tcaggtccct gaagactcca
      241 gttcggagag gagaattgca cctactgctt tcaggcacca taaatcaaaa aacgttaggg
      301 gacagatgtt gcggtgagaa acccgtgatg aagatgtcct tgtccccggg aagcaggagg
      361 tagagaagtt ccctgcaggc tgtgggcgaa tcccactgcc tggttcccac catgaaggat
      421 cttccagcat tcccttgcag ctgggtctgg ctactctggt ccttttgcag cgtccaggtg
      481 tgtagcactc agcccagagc ccaggaacat ccaggctttg cggtcttggc ttctgcttct
      541 cattactggc cattggaaaa tgtggatggg atccttgagc ttcaggacac aactggagat
      601 atcatggaag ggaaggtgaa caaaggcatt tacctcaagg aggagaaggg cgtgacgttt
      661 ctctactatg gcacctacaa gtcatcctgt attagcaacc cggcccagtg tggaccagag
      721 ggagtgacat tttcattctt ctggaagact caaggagacc agacccgacc agccccgtac
      781 gcatacgggg gacaggtcgt ctctgacggg ttcaaagtct gctctagtgg tggaaagggc
      841 tctgtggagc tgtacacacg tgataattcc atgacgtgga aggccacctt caaccctccc
      901 ggtccttact ggactcacgt cctgttcacg tggaaatcca aggagggcct gaaggtctac
      961 gtcaatggga ctctgagcac ctcggacccc agcgggaaag tgtcacacac ctacggggat
     1021 ccccacgtca acctggtcat agggtcagag caggaccaga ccaagcgtta cgaaaacgga
     1081 gcttttgatg aattcatcat ctgggaacgg gcactgactc ctgacgagat caagatgtac
     1141 tttaccgctg ccattggtaa acatgctctg ttgtcttcaa caccaccagc gatgcccacc
     1201 gcacacaccg tgatacccac agatgcctac caccctatca tcaccaacct gaccgaggag
     1261 agaaaacgct tccagagacc gggaactgtg ctgagatacc ttcaaaatgt gtccctccgc
     1321 ttgcccaata aatccctctc agaggaaacg gcgctgaacc tcacagagac cttcttaaga
     1381 acggtgggtg aggtcctcct actgcccagc tggacccatg aatcagagga caacgccatg
     1441 acgctgggcc tggttgacac catcgatacc gtcatgggcc acatatcatc caacctacag
     1501 tccagagaac cccatgtcac cctcacaggc tcgtcctcca cggcagaatt cactgtggcc
     1561 aaggtcctcc caccagcgct cagtgctccc cactatagat tcccagccca tgggcatagc
     1621 tacattgaaa ttccgagaga ggcccttcac agccaagcct ggaccacgat tgtcggcctt
     1681 ctctaccaca ccatgcacta ttatctgaaa aacatccacc caaccagcac agagatcccc
     1741 gaggctgtga actgcagaga ctgcctgctg tctgtcgcca gccacctgat ctccctggag
     1801 gtgtccccac cacccactct gtcccagaac ctatccggct ctcctctgat cactgtgcat
     1861 ctcagacaca aactgactca aaagcagtac agcgatgcca ccaatgagag caaccgtctc
     1921 ttcctgtatt gcgccttcct taacttcagc tccggggaag gcgtctggtc cagccagggc
     1981 tgtgcactca cagaaggaaa tctcacttat tcagtgtgcc actgcacaca cctcaccaac
     2041 ttcgccatcc tcatgcaagt ggtcccactg aagctcacac atggacacca ggtggcgctg
     2101 tcgtccatca gttacgttgg ctgctctctg tcagttctct gcctggctgc caccctggtc
     2161 accttcgcag tactgtcttc tgtcagcacc attcggaacc agcgttacca catccacgcc
     2221 aacctgtcct tcgctgtcct ggtagcccag gtcttgctgc tgatcagctt cagcatggag
     2281 cctggcacgg tcccgtgcca ggtgctggct gtcctcctac attacttctt cctgaccgcc
     2341 tttgcttgga tgctggtgga gggactacat ctctacagca tggtgataaa ggtcttcggc
     2401 tcagaggaca gcaagcacct ctactactat gggataggct gggggtgccc tctcctcatc
     2461 tgcatcatct ccatatcatc ctctatggac agctatggga caagtgacag ctgctggctg
     2521 gctctgggga gtggcgctat ttgggccttt gtgggcccgg ctctgttggt cattgtggtc
     2581 aacattgtta tcctggttgc tgtgacgagg gtcatctccc acatcagcac tgatagctac
     2641 aagatacatg gggaccccag tgccttcaag ttgacagcca aggctgtggc tgtgctgcta
     2701 cccattctgg ggacctcatg ggtatttggg gtgcttgccg tcagtgaccg ggccctggtc
     2761 ttccaataca tgtttgctat actcaactct ttacagggcc tcttcatctt tctctttcac
     2821 tgtctcctga actcagaggt aagggctgcc ttcaagcaca agaccaaggt ctggtccctc
     2881 acgagcagct ctgcccggac cgcgaacacg aagcctttca gttcagacac cgtcaatggg
     2941 acccgtccag gcacggcatc tacaaagcta agcccttggg ataagagcag ccattctgcc
     3001 caccgtgtcg acctatccgc tgtgtgagca gggtgacctc tgttcaaaag aagtgccttc
     3061 cctgaagcag agaaaaaaat gtataccctg cctacatcct gggtccctct tcttcttgat
     3121 accttggcct gggataatgg cccctaccta tgactgtgca gaacgtcctg cctggcactg
     3181 caagtggact cagggtggtg agggcagcag tgatgtagcc ctccttccct ggtgtggtgg
     3241 gcacttctgt cctctgtgga caccagagtg cagagtagcc catggtgacc actaagaccg
     3301 gacctccctt gttatcgtat gcacagagca acatcccagc aagcctgcat taaatgacat
     3361 gtaaagatgg ggctagagga catagcctca gccttgaagg agactcacag tcctgagggc
     3421 tactcaatgt cttatggttc tccagagggt ccacagaggt ggtagccgag ccatgtaggg
     3481 gaatgaagcc agcaccaatt ggaatgtaca tcttcacgta aggggacact aattgagcca
     3541 ccacccaccc tagctgtaca gccagttctg gactctccgc ctttgcccgt ttggagtcgc
     3601 ccactatccc ttgtatggat ctttgtgaag acagtctaaa ggagccactt catgggaccc
     3661 gatgctgtct attctctgca agttgttcct tgatggacct aaagtcagcc ttagaatatt
     3721 cttttcaaac acgagcctct ctactgtcca tgacctcctt gggggctgag cttccctgct
     3781 gggtgtcccc ctgtacctgt atgtcctggc tttctgggag tgttgctacc cctagggtct
     3841 gtgttctcat tatttagacg tgcctcctcc gtaagagcca acaggcatca gacagcttag
     3901 acattggatg tccctcatgt gacagaccag accagccaca ttgcagaggc tgatttcctc
     3961 ccagtaaggg gtggggggca caccaagtct ctgctgctgg ccagggtgac cactgtaagc
     4021 tttgggtttg gtgtgagtgg acagaaatag actcagccct gggaagtaca gtcattgtga
     4081 caacaaggtc cacatggaga tggagatccc cgaggactaa ggagcaggct gtgaagggcc
     4141 aaccagtgtg acaaggagct taagtgtctg tgacatgcac agcctagatg gccagtctgg
     4201 ccccaatact ggaaaactct cacttcccat gagatcccta acagccctga gccccttctt
     4261 attcccatgc cttacttggc tttaggatat gtttccgctc agatcttttc agcttaaatg
     4321 ttctctgttc ttttctccac tgtaatgaag tagagccaag gcctggcata gccaggcaag
     4381 cactccacac tgagccacac cccagcccct aagtgacaat ttcctacagg cgtccagaag
     4441 ccacaaggct ataaggccag actttgctct ggctaagcca ggactgaaat ctattagcca
     4501 aatgggaccc tctgacctac cctcctgcag cccctttggc cagtgcaggc tgaggccatg
     4561 ctgagactct gtatctggtg acaagtcctg ttctaaagaa tgtgggtggt ctctgctcag
     4621 catctcatcc ttcctcaaac caaacaccgg tgacccaggg tcccacctgc cctgctgagc
     4681 tcctagtagt gagaacactg tatccctccc atgcacgctg gactcccact aaagcaaggc
     4741 agaccaggcc agtcctttat tcccagtggg attctcagtt tctggctttt ttttttaata
     4801 ctcgctctta tgtagctgat atatcaaggg aagtcaagag caaaacctgt ctcggcttcc
     4861 catctccagt gagtgaaagc gtgtgcttta tttataggct cccgactctg gcttctgcag
     4921 tcatttgtta tctgtgtata atttggccct acataaatta ggaagaatgg tgtgtgtgcg
     4981 tcgtttgtgg cagagggacg atgatgagtc gctgctatag tgaagacatg ttgtgatttt
     5041 gatgaaataa actcttaatg tccttaa
//
