LOCUS       NM_054044               5520 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus adhesion G protein-coupled receptor A2 (Adgra2), mRNA.
ACCESSION   NM_054044
VERSION     NM_054044.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5520)
  AUTHORS   Xu,Y., Fang,X., Zhao,Z., Wu,H., Fan,H., Zhang,Y., Meng,Q., Rong,Q.,
            Fukunaga,K., Guo,Q. and Liu,Q.
  TITLE     GPR124 induces NLRP3 inflammasome-mediated pyroptosis in
            endothelial cells during ischemic injury
  JOURNAL   Eur J Pharmacol 962, 176228 (2024)
   PUBMED   38042462
  REMARK    GeneRIF: GPR124 induces NLRP3 inflammasome-mediated pyroptosis in
            endothelial cells during ischemic injury.
REFERENCE   2  (bases 1 to 5520)
  AUTHORS   America,M., Bostaille,N., Eubelen,M., Martin,M., Stainier,D.Y.R.
            and Vanhollebeke,B.
  TITLE     An integrated model for Gpr124 function in Wnt7a/b signaling among
            vertebrates
  JOURNAL   Cell Rep 39 (9), 110902 (2022)
   PUBMED   35649360
  REMARK    GeneRIF: An integrated model for Gpr124 function in Wnt7a/b
            signaling among vertebrates.
REFERENCE   3  (bases 1 to 5520)
  AUTHORS   Wang,Y., Venkatesh,A., Xu,J., Xu,M., Williams,J., Smallwood,P.M.,
            James,A. and Nathans,J.
  TITLE     The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential
            role in mammalian limb development
  JOURNAL   Development 149 (9) (2022)
   PUBMED   35552394
  REMARK    GeneRIF: The WNT7A/WNT7B/GPR124/RECK signaling module plays an
            essential role in mammalian limb development.
REFERENCE   4  (bases 1 to 5520)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5520)
  AUTHORS   Maroney,S.A., Westrick,R.J., Cleuren,A.C., Martinez,N.D.,
            Siebert,A.E., Zogg,M., Ginsburg,D., Weiler,H. and Mast,A.E.
  TITLE     Tissue factor pathway inhibitor is required for cerebrovascular
            development in mice
  JOURNAL   Blood 137 (2), 258-268 (2021)
   PUBMED   32735640
REFERENCE   6  (bases 1 to 5520)
  AUTHORS   Vallon,M., Rohde,F., Janssen,K.P. and Essler,M.
  TITLE     Tumor endothelial marker 5 expression in endothelial cells during
            capillary morphogenesis is induced by the small GTPase Rac and
            mediates contact inhibition of cell proliferation
  JOURNAL   Exp Cell Res 316 (3), 412-421 (2010)
   PUBMED   19853600
REFERENCE   7  (bases 1 to 5520)
  AUTHORS   Homma,S., Shimada,T., Hikake,T. and Yaginuma,H.
  TITLE     Expression pattern of LRR and Ig domain-containing protein (LRRIG
            protein) in the early mouse embryo
  JOURNAL   Gene Expr Patterns 9 (1), 1-26 (2009)
   PUBMED   18848646
REFERENCE   8  (bases 1 to 5520)
  AUTHORS   Bjarnadottir,T.K., Fredriksson,R., Hoglund,P.J., Gloriam,D.E.,
            Lagerstrom,M.C. and Schioth,H.B.
  TITLE     The human and mouse repertoire of the adhesion family of
            G-protein-coupled receptors
  JOURNAL   Genomics 84 (1), 23-33 (2004)
   PUBMED   15203201
REFERENCE   9  (bases 1 to 5520)
  AUTHORS   Valenzuela,D.M., Murphy,A.J., Frendewey,D., Gale,N.W.,
            Economides,A.N., Auerbach,W., Poueymirou,W.T., Adams,N.C.,
            Rojas,J., Yasenchak,J., Chernomorsky,R., Boucher,M., Elsasser,A.L.,
            Esau,L., Zheng,J., Griffiths,J.A., Wang,X., Su,H., Xue,Y.,
            Dominguez,M.G., Noguera,I., Torres,R., Macdonald,L.E.,
            Stewart,A.F., DeChiara,T.M. and Yancopoulos,G.D.
  TITLE     High-throughput engineering of the mouse genome coupled with
            high-resolution expression analysis
  JOURNAL   Nat Biotechnol 21 (6), 652-659 (2003)
   PUBMED   12730667
REFERENCE   10 (bases 1 to 5520)
  AUTHORS   Carson-Walter,E.B., Watkins,D.N., Nanda,A., Vogelstein,B.,
            Kinzler,K.W. and St Croix,B.
  TITLE     Cell surface tumor endothelial markers are conserved in mice and
            humans
  JOURNAL   Cancer Res 61 (18), 6649-6655 (2001)
   PUBMED   11559528
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF378759.1 and CJ243065.1.
            
            On Jul 21, 2010 this sequence version replaced NM_054044.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF378759.1, BC138451.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5503              AF378759.1         1-5503
            5504-5520           CJ243065.1         438-454
FEATURES             Location/Qualifiers
     source          1..5520
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 15.91 cM"
     gene            1..5520
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /note="adhesion G protein-coupled receptor A2"
                     /db_xref="GeneID:78560"
                     /db_xref="MGI:MGI:1925810"
     exon            1..371
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..4116
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /note="G-protein coupled receptor 124; tumor endothelial
                     marker 5; G protein coupled receptor Gpr124"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor A2
                     precursor"
                     /protein_id="NP_473385.2"
                     /db_xref="CCDS:CCDS22210.2"
                     /db_xref="GeneID:78560"
                     /db_xref="MGI:MGI:1925810"
                     /translation="MGAGGRRMPVPPARLLLLPLLPCLLLLAPGTRGAPGCPVPIRGC
                     KCSGERPKGLSGGAHNPARRRVVCGGGDLPEPPDPGLLPNGTITLLLSNNKITGLRNG
                     SFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLR
                     LNISGNIYSSLQPGVFDELPALKIVDFGTEFLTCDCRLRWLLPWARNHSLQLSERTLC
                     AYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGND
                     TRIHWYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQ
                     GNTSKKVEIVVLETSASYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSG
                     GAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVY
                     TAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQRE
                     DKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTAFQRREV
                     GVSGAQPSSVGQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPS
                     LFSTLPAALAPPVPPDCTLQLLVFRNGRLFRSHGNNTSRPGAAGPGKRRGVATPVIFA
                     GTSGCGVGNLTEPVAVSLRHWAEGADPMAAWWNQDGPGGWSSEGCRLRYSQPNVSSLY
                     CQHLGNVAVLMELNAFPREAGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHV
                     SRKGWHMLLNLCFHMAMTSAVFVGGVTLTNYQMVCQAVGITLHYSSLSSLLWMGVKAR
                     VLHKELSWRAPPLEEGEAAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPY
                     CWLVWRPSLGAFYIPVALILPITWIYFLCAGLHLRSHVAQNPKQGNRISLEPGEELRG
                     STRLRSSGVLLNDSGSLLATVSAGVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMW
                     ACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPSA
                     SHVPARALPTATEDGSPVLGEGPASLKSSPSGSSGRAPPPPCKLTNLQVAQSQVCEAS
                     VAARGDGEPEPTGSRGSLAPRHHNNLHHGRRVHKSRAKGHRAGETGGKSRLKALRAGT
                     SPGAPELLSSESGSLHNSPSDSYPGSSRNSPGDGLPLEGEPMLTPSEGSDTSAAPIAE
                     TGRPGQRRSASRDNLKGSGSALERESKRRSYPLNTTSLNGAPKGGKYEDASVTGAEAI
                     AGGSMKTGLWKSETTV"
     exon            372..443
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            444..515
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            516..587
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            588..659
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            660..823
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1037
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1202
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1401
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1551
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1713
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..1938
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            1939..2158
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            2159..2358
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2486
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            2487..2610
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            2611..2756
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2846
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     exon            2847..5517
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5413..5418
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /note="hexamer: AAGAAA"
     polyA_site      5465
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /note="major polyA site"
     regulatory      5487..5492
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /note="hexamer: ATTAAA"
     polyA_site      5517
                     /gene="Adgra2"
                     /gene_synonym="8430414O08Rik; 9530074E10Rik; Gpr124;
                     mKIAA1531; Tem5"
                     /note="major polyA site"
ORIGIN      
        1 gggcgcccgg gactcccgct gagcactcct cccgcacgcc cgggtccctc cggccggcga
       61 gccgtccggc ccctgcgctg taggtccccg cggggcgatg ggttgatggg cgcgggggga
      121 cgcaggatgc cggtgcctcc cgcgcgtttg ctgctgctgc cgctgctgcc ttgtcttctg
      181 ctcctggctc ctggaactcg gggtgcgcct ggctgcccgg tccctatccg cggttgcaag
      241 tgctctgggg agcggcccaa gggactaagt ggcggcgccc acaacccggc tcgaaggagg
      301 gtggtgtgcg gcggtgggga tctccccgaa cctccagatc ccggccttct gccaaacggc
      361 accatcacct tgctcttgag caacaacaag attactgggc tccgcaatgg atccttcttg
      421 ggactgtccc tgttggagaa gttggacctg aggagcaatg tcatcagcac tgtgcagcct
      481 ggagccttcc taggtctggg agagctaaaa cgcttagatc tctccaacaa tcggattggc
      541 tgtctcacct ctgagacatt tcaagggctc cctagacttc tcagactaaa catatctgga
      601 aacatctact ctagtctgca acctggggtc tttgatgagc tgccagccct taagattgtg
      661 gactttggta ctgagtttct gacctgtgac tgccgcctgc gctggctgct gccctgggcc
      721 cggaatcact ccctgcagct gtctgagcgc acactctgtg cctaccccag tgccctgcac
      781 gcccatgccc tgagcagcct ccaggagtcc cagcttcgct gtgaaggggc cctggaactg
      841 cacacccact acctcatccc atcccttcgc caagtggtgt tccagggtga ccgcctgccc
      901 ttccagtgct cagccagcta cttgggcaac gatacccgga tccactggta ccacaatggg
      961 gctcctatgg agagcgatga gcaggccggc atcgtccttg ctgaaaacct tatccatgat
     1021 tgcaccttca tcaccagtga gctgaccctg tctcacattg gtgtgtgggc ctctggtgaa
     1081 tgggagtgct ccgtgtccac agtccaaggc aacaccagca agaaggtgga gatagtagtg
     1141 ctggagacct ctgcctccta ctgccctgca gagcgggtga ccaacaaccg tggggacttc
     1201 aggtggcccc gaaccttggc tggcatcacg gcttaccagt cctgtttaca gtaccccttc
     1261 acctctgtgc ccttgagtgg gggagccccg ggtacccgag cctcacgcag gtgtgaccga
     1321 gctggccgct gggagccagg ggactactcg cactgtctgt acaccaatga catcactcgg
     1381 gtgctctaca cctttgtgct gatgcccatc aacgcctcca atgcattgac gttggcccac
     1441 cagctgcgag tgtataccgc agaggccgcc agcttctcag acatgatgga cgtggtctat
     1501 gtggctcaga tgatccagaa gtttttgggt tacgttgacc agatcaagga gctggtggag
     1561 gtgatggtgg acatggccag caacctgatg ctggtggatg agcaccttct gtggctggcc
     1621 cagagagaag acaaagcctg cagtggcatt gtgggtgccc tggagcgaat cggaggagct
     1681 gctcttagcc cccatgccca gcacatctct gtgaattcaa gaaatgtggc actggaggcc
     1741 tacctcatca agcctcacag ctacgtgggt ctgacttgca cggctttcca gaggagggag
     1801 gtaggagtgt cgggtgcaca gccaagcagc gtcggccagg atgccccagt ggagcccgaa
     1861 cccctagctg atcagcagct taggttccgc tgcaccactg ggaggcccaa catttctctg
     1921 tcatccttcc acatcaagaa tagcgtggcc ctggcctcca tccagctgcc ccccagcctg
     1981 ttctcaaccc ttccggctgc cctggctccc ccagtccctc cagattgcac cctgcaactg
     2041 ctggtcttca gaaatggccg tcttttccgc agccacggca acaacacttc ccgtcctgga
     2101 gcagctgggc ctggcaagag gcgtggtgtg gccaccccag tcatatttgc aggaaccagt
     2161 ggctgtggtg tgggaaactt gacggagccc gtggctgtgt cactgaggca ctgggctgaa
     2221 ggagctgacc ccatggcagc ttggtggaac caggacgggc ctggaggctg gagttctgaa
     2281 ggctgcaggc tccgctacag ccagcccaac gtcagctccc tgtactgcca gcacttgggc
     2341 aatgtggccg tgcttatgga gctgaatgca ttcccgcggg aggcaggagg ctctggggct
     2401 gggttgcatc ccgtcgtgta cccctgcacg gctttgctgc tactctgtct cttctccacc
     2461 atcatcacgt acatcctcaa ccacagctcc atccacgtgt cccggaaggg ttggcacatg
     2521 ctgctgaacc tttgtttcca tatggccatg acctctgctg tcttcgtggg gggcgtcacg
     2581 ctcaccaact accaaatggt ttgtcaagcg gtgggcatca ctctgcacta ctcttccttg
     2641 tcgtcactgc tctggatggg ggtcaaggct cgagtcctcc acaaggagct tagttggagg
     2701 gcaccccctc tggaagaagg ggaagcagct ccgcctggtc ctcgccccat gctccggttc
     2761 tacttgattg ctggagggat ccccctcata atctgcggca tcaccgctgc ggtcaacatc
     2821 cacaactacc gggaccacag tccctattgt tggctggtgt ggcgtccaag ccttggtgcc
     2881 ttctacatac cggtggcgtt gattctgcct atcacctgga tctacttctt gtgtgcaggc
     2941 cttcacttac ggagccatgt ggcccagaat ccaaagcagg gtaacaggat ctctctggag
     3001 ccaggggaag agctgagggg ttccaccagg ctcaggagta gtggcgtcct cctgaatgac
     3061 tctggttctc ttttggctac agttagcgca ggagtaggga cacctgcgcc cccagaggat
     3121 ggtgatggcg tatattctcc tggagtccag ctgggggcgc tgatgaccac gcatttcctg
     3181 tacctggcta tgtgggcttg tggtgccttg gcggtgtctc agcgctggct gccccgagtg
     3241 gtgtgtagct gtctgtacgg cgtggcagct tcagctcttg gtctgtttgt cttcactcac
     3301 cactgtgcca gacgtagaga tgtccgggct tcctggcgcg cctgctgccc tcctgcttcg
     3361 ccctcggcct cccatgtccc agcccgggcc ctgccgactg ctacagagga tggatcccca
     3421 gtgttggggg agggaccagc ctctctcaag tcctccccaa gtggcagcag tggccgcgcg
     3481 ccgccacccc cctgcaaact caccaatctg caggtggccc agagtcaggt gtgcgaggca
     3541 agcgtggccg cccgcggaga tggagagcca gagcccaccg gctcccgtgg cagcctagct
     3601 ccccggcacc ataacaacct gcatcatggg cgccgagtac acaagagtcg ggccaagggg
     3661 caccgagccg gagagactgg tggtaagagc cggctcaagg cgttgcgcgc gggcacgtcc
     3721 ccaggagctc ccgagctgtt gtccagtgag agcggcagtt tgcacaacag cccgtctgac
     3781 agctacccgg gcagcagccg caacagtcca ggcgacggtc ttccactcga gggtgagccc
     3841 atgcttacgc cgtcggaggg cagtgacaca agcgccgcgc caatcgctga gacggggcgc
     3901 cccgggcagc gccgcagcgc cagccgtgac aacctcaagg gcagcggcag cgcgctggag
     3961 agggagagca agcgccgctc ctatccgctc aacactacca gtcttaacgg tgcccccaaa
     4021 gggggcaagt atgaggatgc cagtgtaact ggtgcagagg ccatagcggg aggctccatg
     4081 aagactggcc tctggaaaag cgagaccacc gtctaggtcc agatttagga tgggcgggtc
     4141 acgcgggctt gtttactccc aaatcctctt gggcggtcca agccgtctac tgatgtgtat
     4201 gtaggtttaa ggcggccatg ctgatgctgc ccttgagtcc accatcatta gttacccagg
     4261 ctagggaaag gggagggagg cagatgcttg cccctactgt ggactatccc tcagcagtag
     4321 cgacagacaa tcccagacca gttttggtgg ccaagttctt ggtatcctgc caggtaggca
     4381 taaaacatcc atcggtccct agggtaaccc ataaactgag ttgaagagcc cagcccaggt
     4441 aggctcagga aatgagaggg agaccgggga actgggttct ccacaccagc ccggcaaggt
     4501 atcctgtgac tgccaagatc ccaggcctct ctcccagttt tggcttggga aaccatccca
     4561 gcaggtgagc cagggggcgt aacaggtgct gcctttcaga ttaactatgc aagggggatg
     4621 ggggtgggag gggtagggca gtgtggtggg cagctctaga gatgagcttg tccctcagga
     4681 ggcaggcagg tgggaaaagg tgcattaggg agacagaatc cctaactatg ggagtggtac
     4741 acagtttttc cagcagagtt cacagcaaac cctgaacccc cacacacctg ggaagtgata
     4801 ctgccagcag gtgccttaag actcaagggg agggagctga tatgtggatc tcacaaccta
     4861 tacagtggtc tgcaagtggc tccacttagc tgcttaatta taatacccac tgtctgttcc
     4921 cagccctcca actccggggg actgagggga aatgcctcca tgaggctcct gtggcaaagc
     4981 catgctaata atctgacttc taacctcagt tagaaaccca aaatgccaaa ccacctccta
     5041 actcgctgaa acccaaccac actctgaggc agcgcctggg tccaggctgc tcaagagcct
     5101 atgcttccag cccccatttt cctcaactca agatgccttt taatacagaa ctacatggaa
     5161 gtagaggaac ccttgggcac tgggaagtag cagggatccc agctctgatc aagtgagagg
     5221 acagagcagg gaagacgcca tactcgctga gatgggtccc attatttatg ctttgctgca
     5281 cagacactat tagaggaaaa gctttgtatt actctcccac gtgagctgct gctgtttacc
     5341 ctgccaatgc cttagcactg gagagctttt tgcaatatgc tggggaaagg ggagggaggg
     5401 gatgaagtgc caaagaaaac acattttaaa agctctggtt ttatacaata gaatgttttc
     5461 cagcagatgc ctctttgttt taatatatta aaatcttgca aaactctttg agcgacaaaa
//
