LOCUS       NM_001127353            5297 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus androglobin (Adgb), mRNA.
ACCESSION   NM_001127353 XM_003084831 XM_003085670
VERSION     NM_001127353.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5297)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5297)
  AUTHORS   Qu,R., Zhang,Z., Wu,L., Li,Q., Mu,J., Zhao,L., Yan,Z., Wang,W.,
            Zeng,Y., Liu,R., Dong,J., Li,Q., Sun,X., Wang,L., Sang,Q., Chen,B.
            and Kuang,Y.
  TITLE     ADGB variants cause asthenozoospermia and male infertility
  JOURNAL   Hum Genet 142 (6), 735-748 (2023)
   PUBMED   36995441
  REMARK    GeneRIF: ADGB variants cause asthenozoospermia and male
            infertility.
REFERENCE   3  (bases 1 to 5297)
  AUTHORS   Keppner,A., Correia,M., Santambrogio,S., Koay,T.W., Maric,D.,
            Osterhof,C., Winter,D.V., Clerc,A., Stumpe,M., Chalmel,F.,
            Dewilde,S., Odermatt,A., Kressler,D., Hankeln,T., Wenger,R.H. and
            Hoogewijs,D.
  TITLE     Androglobin, a chimeric mammalian globin, is required for male
            fertility
  JOURNAL   Elife 11, e72374 (2022)
   PUBMED   35700329
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5297)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
REFERENCE   5  (bases 1 to 5297)
  AUTHORS   Hoogewijs,D., Ebner,B., Germani,F., Hoffmann,F.G., Fabrizius,A.,
            Moens,L., Burmester,T., Dewilde,S., Storz,J.F., Vinogradov,S.N. and
            Hankeln,T.
  TITLE     Androglobin: a chimeric globin in metazoans that is preferentially
            expressed in Mammalian testes
  JOURNAL   Mol Biol Evol 29 (4), 1105-1114 (2012)
   PUBMED   22115833
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159380.8 and AC153567.6.
            
            On Mar 7, 2019 this sequence version replaced NM_001127353.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN01164133 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               AC159380.8         130077-130235       c
            160-322             AC159380.8         107803-107965       c
            323-415             AC159380.8         103993-104085       c
            416-487             AC159380.8         101230-101301       c
            488-697             AC159380.8         100321-100530       c
            698-837             AC159380.8         93770-93909         c
            838-924             AC159380.8         91249-91335         c
            925-1042            AC159380.8         89118-89235         c
            1043-1172           AC159380.8         88907-89036         c
            1173-1307           AC159380.8         84435-84569         c
            1308-1402           AC159380.8         80502-80596         c
            1403-1577           AC159380.8         69550-69724         c
            1578-1668           AC159380.8         68623-68713         c
            1669-1798           AC159380.8         65278-65407         c
            1799-1832           AC159380.8         64953-64986         c
            1833-2010           AC159380.8         63794-63971         c
            2011-2074           AC159380.8         63121-63184         c
            2075-2177           AC159380.8         60741-60843         c
            2178-2319           AC159380.8         58419-58560         c
            2320-2434           AC159380.8         56693-56807         c
            2435-2602           AC159380.8         54152-54319         c
            2603-2738           AC159380.8         53075-53210         c
            2739-2876           AC159380.8         52392-52529         c
            2877-2970           AC159380.8         49520-49613         c
            2971-3105           AC159380.8         48651-48785         c
            3106-3259           AC159380.8         47972-48125         c
            3260-3447           AC159380.8         40561-40748         c
            3448-3632           AC159380.8         36501-36685         c
            3633-3832           AC159380.8         35678-35877         c
            3833-3944           AC159380.8         15703-15814         c
            3945-4115           AC153567.6         225892-226062       c
            4116-4300           AC153567.6         223251-223435       c
            4301-4430           AC153567.6         222469-222598       c
            4431-4598           AC153567.6         219406-219573       c
            4599-4689           AC153567.6         213433-213523       c
            4690-4873           AC153567.6         212546-212729       c
            4874-5297           AC153567.6         208702-209125       c
FEATURES             Location/Qualifiers
     source          1..5297
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 3.44 cM"
     gene            1..5297
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /note="androglobin"
                     /db_xref="GeneID:215772"
                     /db_xref="MGI:MGI:3605549"
     exon            1..159
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            160..322
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            323..415
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            416..487
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            488..697
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            698..837
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            838..924
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1042
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1172
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1307
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1402
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1577
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1668
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1798
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1832
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..2010
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2074
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2177
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2319
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2434
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2602
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2603..2738
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2739..2876
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2877..2970
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2971..3105
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3106..3259
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3260..3447
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3448..3632
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3633..3832
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3833..3944
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3945..4115
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4116..4300
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4301..4430
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4431..4598
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4599..4689
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4690..4873
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4874..5297
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5274..5279
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5297
                     /gene="Adgb"
                     /gene_synonym="9130014G24Rik"
                     /note="major polyA site"
ORIGIN      
        1 agacgctgga agtctcctgg gccttggggc gcgctctcag cgggcgggcg ggcgctgctg
       61 gaggctgcta gagtgggccg caggcatggc ttccaaacaa gctaaaagga aagaagtgca
      121 tcggatcaat tccgcgcatg gatcagataa atctaaagat ctctaccatt ttggcagcaa
      181 tgtgccaccg ggttcttttg aacagaagaa gggaaagttc cccatctggc cagagtggag
      241 cgaggcagac ataaatgctg aaaagtggga tgcaggcaaa ggcgggaagg agaaggacaa
      301 gaccgccaag agccccatct ttcacttttt cgaagaccct gagggaaaga ttgaattacc
      361 acagtcattg aaagtattct cctggaaacg tccgcaagat tttatattta gcagaactcc
      421 tgtagttgtg aaaaatgaaa tcacatttga cttattttca ccaaatgaac atttactctg
      481 cagtgagctt atgaggtgga tcatcagcga aatctatgct gtgtggaaga tattcaatgg
      541 tgggattctg agcaattacc acaaggggaa tttgggggag cttcctattc tgccctggaa
      601 accctgggaa cacatatact ctctctgcaa ggccgtgaag ggtcatgtgc ctttgttcaa
      661 cagctacggg aagtatgtcg tcaaacttta ctggatgggt tgttggagaa agattactgt
      721 ggatgacttc ctgccatttg atgaggagaa caatctcttg cttccagcta catcctatga
      781 atttgaactc tggccaatgc tactgtcgaa agctatcatt aagctggcaa atgttgacgt
      841 ccatgtagca cacaggagag agctaggaga actcacagta atccacgctc tgactgggtg
      901 gttgcctgaa gtcatccctc ttcacccagc atatgtggac agagtttggg agctcttgaa
      961 ggaaatactg cctgagttta agctcacaga agagcccagt tctgaaagca aaatcacaac
     1021 gatagacaac aaactgaagg aagatggcaa ggacgggaag gatgggaagg atggcaagga
     1081 tgggaaggat ggcaaggaca gcaaggactt caagttggaa gtctccctta caaacctgaa
     1141 gattcccgag aaggtcgaca gagctgcaaa ggagaaagca gatgcaagag accttgggaa
     1201 gaagaataag aaggatggag agaaggagaa ggaaaaattc aaattttcac tccatggttc
     1261 gagaccctca tcagatgttc agtactctat gcagtccttg tcagagtgtt cctcagcaat
     1321 acagttacct cacatggtcg tatatgccac ctttacacca ctctatttgt ttgaaaacaa
     1381 aatcttttca ttagagaaga tggcgaattc tgcggagaaa cttagggaat atggtctttc
     1441 tcacatctgt agccatcctg tgctggtgac cagaagtagg tcttgccctc ttgtgtcacc
     1501 ccccaaacct cctcccttac ctgcctggaa actcattcgc cataaaaagg aaacagtgat
     1561 aaccgatgaa gctcaagatg ctgtcccgaa gaagcctgag cagttccttg agatttcaag
     1621 tccatttttg aattatagaa tgactccatt tacgattcca acagaaacac attttgtcca
     1681 atctgtcatt aagaaaggaa caccgctggg atccagtctt cctcccctcg tggaaaatga
     1741 tttagttgca agtaccagcc aaggggaaat gagcatagta aatggaaacc agtctcaggg
     1801 caatattgca ttgcaaatta cacttggaaa agatgaacct tcagagcctg cattggcgga
     1861 cttccaccaa cttgaggcta ctagtttgga cagggatttg atcagcctga ctacagcgac
     1921 actggacaag tcacaggaag agttagcaat aaacgaaggg gttgccaaag agatatggtt
     1981 agacttcgaa gacttttgtg tgtgctttca ccatatatat attttccaca agccacattc
     2041 ttattgtctt aattttcaaa aatcagaatt caagtttgtg gaagagcgtg tgccttacta
     2101 tctatttgtg gacagcctga agcctataga actactggtt tgcttttccg ctttggtgcg
     2161 ctggggggaa tctggagcct taacaaaaga tagccctcct gtggagcctg gactcctgac
     2221 agctgaagcc atcacctgga aatccctgaa gcctcttagt gttgttctga gaattcacac
     2281 ctatgctacg aaggccagcg tggtgcgcct gcctgccggg aggcatatgc tgctcttcaa
     2341 tgcgtattcc cctgtgggcc atgccataca tgtctgcagc atgacaacat ttgtcattgg
     2401 ggatgaagat attgtactgc ccaactttga gccggagagc taccgattta cagaacagtc
     2461 tataataatt atgaaagcta ttggcaacgt gattgctaat ttcaaagaca aaggtaaatt
     2521 gcctgcagct ctgagggatc tgcaagcagc tcactaccct atccccctca acaacaaaga
     2581 actcactgct caacacttcc gggttttcca tatatcattg tggcgtttaa tgaaaaaatc
     2641 tcaagtagcc aagcctcctt caaacttcaa gtttgcattt cgggctatgg tttttgacac
     2701 ggacttactg gattctttct cagaggatgt ttctttagcg gaatgggtcg accttaaata
     2761 ttctacacca ataaatgaga aggagtatac ctccgaggaa atagctgctg cggtgaaaat
     2821 tcaatccatg tggaaagggt gctatgtcag actgctcatg aaagccagaa agccagaaac
     2881 aaaggaaaat gtcaccgttg cagatacact tcagaaaatt tgggcagtat tggagatgaa
     2941 tttggagcaa tatgcattgt ctctcttaag actaatgttt aaaagcaaat gtaagtctat
     3001 ggaatcctac ccatgctatc aagatgaaga aaccaagttg gcctttgctg accacactgt
     3061 gaactatgca gaccagcctc cgaattcttg gtttatagta ttcagagaaa tatttttggt
     3121 tcctcaagat atgatcatac tccccaaagt gtacactaca ctcccgatct gtatattgca
     3181 tgtcattaac aatgacacgt tggagcaggt gccaaaagtg tttcagaaag tggtgccttt
     3241 cctttacacc aagaacaaga agggatacac atttgtggct gaagcatata ctggtgacac
     3301 attcgtatca ggagcacgat ggaaactgcg gctcatcggc tcttacaacc cgctcccgtt
     3361 tctcgcccgt gactcaccat gcaacacctt ctccataaag gaaatcagag actactacat
     3421 tcctaatgac aggaagatcc tgttcaggta ctccattaaa gtgacagtgg cacagtctat
     3481 tacaatccag gtccgcacat ccaaacccga caccttcatc aagctgcagg tgctggagag
     3541 tgaggaggtt atcaccagca ccgtgggcaa agggcaagct gtcatccctg ccttctactt
     3601 ccttggaaat gaaaaagccc tgagctccca gtctagcaag caagttctct tatctcaccc
     3661 ctcacctaag aaagatccag aagtgctgac caagaaaaag tctggccaac caggtcagaa
     3721 atccttcaaa ggaagatctg gaggtggact aactgacaca ggaatgcccc tgctggaaga
     3781 agaaattttg aacataccca ctctagaaga aaattctagc acgccacaac agtgctataa
     3841 gtacatcata cagtgcctgg tgttgtttaa cagctggcct ctaaacgaaa ctcaactgac
     3901 atttgttcaa gcactaaaag acatggagaa aatggatatc aaagcagaga aacatgaaga
     3961 accagctccc atgggaagcc cagattccca tgcagtcagc gaagggcaga aatctgtagg
     4021 agtgcccaaa acaacccgga aaggcaagga gaaatctgcc gagaaagaaa agttagctaa
     4081 ggaaaagcaa gctcctcgat ttgaacctca ggtggtacaa atgcctactg ctgttcactc
     4141 tcagcaagaa gatccaaaca aaccctactg gatcttgagg ctggtctctg aacacaccga
     4201 ctcagactat gttgacgtaa aaaaagacac agaacgagca gatgaaatac gggccatgaa
     4261 gcaagcttgg gagacgactg aaccggggag ggccatcaag gctgctcagg cccgtttgaa
     4321 gtacctgacc caattcatta agaagccagt caccaccgat accaccacct ctgcccccag
     4381 ccctgagact ttgtctgtga gtcaaagcca aactaaatcc tcagaggaag gagaactaga
     4441 tactgggaaa tatgcagaca tcaaagaact gccaccaaac gcagcaggaa gtgtgctgtg
     4501 gaagaagtgg caaatgacca agaccatcac ctctctgaca aaattcacaa gcagtgagag
     4561 tgtaccgaag gaagagccac cacagaagga gatccctgtg gtccgacaac gatcaccgac
     4621 aattttggaa acatctccac aacaaattcg taaagcacta gagtttttgg atttcagtca
     4681 ttatgtacgg aaaacagctg cggaggccgt gctgcagaca gaggaactga ataagcagca
     4741 agcgatgcag aaggcagaag aaatccacca gtttcggcag caccgctccc gcatcctcag
     4801 catcagagac attgatcaag aagaacggtt taagcaaaag gatgaggttc tggaaatgta
     4861 tggagagatg cgggactctg tagatgaagc ccggcagaag atccttgata tccgggaagt
     4921 gtaccgaaac aagttgctgg aggcagagcg cttgaggatg gaggccttgg cagctcagga
     4981 agctgcagtg aagatagaga tagagaagaa gtcaccagct tctgactcac agaagaagaa
     5041 gaaagtagga aagaaaaagt aacgccccca tggtgcacta tgccacagag gagggagtgt
     5101 tggacgcact atcaatcact ttcctcttga tcaagcatta ggtcaataga aacaggagaa
     5161 aatgttcctc gctcttggtt tctacatttt aatgttaaca tgttggtttc tgttacaaag
     5221 gatttgaaga cactagcttc tcaaatgttc taatttcatt aaaattgcta acaaataaat
     5281 gcttaggttg taaataa
//
