LOCUS       NM_001413272            7826 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus adenylate cyclase 9 (Adcy9), transcript variant 3,
            mRNA.
ACCESSION   NM_001413272 XM_011245805
VERSION     NM_001413272.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7826)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7826)
  AUTHORS   Ferron,M., Merlet,N., Mihalache-Avram,T., Mecteau,M., Brand,G.,
            Gillis,M.A., Shi,Y., Nozza,A., Cossette,M., Guertin,M.C.,
            Rheaume,E. and Tardif,J.C.
  TITLE     Adcy9 Gene Inactivation Improves Cardiac Function After Myocardial
            Infarction in Mice
  JOURNAL   Can J Cardiol 39 (7), 952-962 (2023)
   PUBMED   37054880
  REMARK    GeneRIF: Adcy9 Gene Inactivation Improves Cardiac Function After
            Myocardial Infarction in Mice.
REFERENCE   3  (bases 1 to 7826)
  AUTHORS   Baldwin,T.A., Li,Y., Marsden,A.N., Rinne,S., Garza-Carbajal,A.,
            Schindler,R.F.R., Zhang,M., Garcia,M.A., Venna,V.R., Decher,N.,
            Brand,T. and Dessauer,C.W.
  TITLE     POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium
            channel TREK-1 in heart
  JOURNAL   EMBO Rep 23 (12), e55208 (2022)
   PUBMED   36254885
REFERENCE   4  (bases 1 to 7826)
  AUTHORS   Li,Y., Hof,T., Baldwin,T.A., Chen,L., Kass,R.S. and Dessauer,C.W.
  TITLE     Regulation of IKs Potassium Current by Isoproterenol in Adult
            Cardiomyocytes Requires Type 9 Adenylyl Cyclase
  JOURNAL   Cells 8 (9), 981 (2019)
   PUBMED   31461851
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7826)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7826)
  AUTHORS   Suzuki,Y., Shen,T., Poyard,M., Best-Belpomme,M., Hanoune,J. and
            Defer,N.
  TITLE     Expression of adenylyl cyclase mRNAs in the denervated and in the
            developing mouse skeletal muscle
  JOURNAL   Am J Physiol 274 (6), C1674-C1685 (1998)
   PUBMED   9611134
REFERENCE   7  (bases 1 to 7826)
  AUTHORS   Premont,R.T., Matsuoka,I., Mattei,M.G., Pouille,Y., Defer,N. and
            Hanoune,J.
  TITLE     Identification and characterization of a widely expressed form of
            adenylyl cyclase
  JOURNAL   J Biol Chem 271 (23), 13900-13907 (1996)
   PUBMED   8662814
REFERENCE   8  (bases 1 to 7826)
  AUTHORS   Antoni,F.A., Barnard,R.J., Shipston,M.J., Smith,S.M., Simpson,J.
            and Paterson,J.M.
  TITLE     Calcineurin feedback inhibition of agonist-evoked cAMP formation
  JOURNAL   J Biol Chem 270 (47), 28055-28061 (1995)
   PUBMED   7499291
REFERENCE   9  (bases 1 to 7826)
  AUTHORS   Paterson,J.M., Smith,S.M., Harmar,A.J. and Antoni,F.A.
  TITLE     Control of a novel adenylyl cyclase by calcineurin
  JOURNAL   Biochem Biophys Res Commun 214 (3), 1000-1008 (1995)
   PUBMED   7575502
REFERENCE   10 (bases 1 to 7826)
  AUTHORS   Premont,R.T.
  TITLE     Identification of adenylyl cyclases by amplification using
            degenerate primers
  JOURNAL   Methods Enzymol 238, 116-127 (1994)
   PUBMED   7528319
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087799.43 and AC132575.3.
            
            On Oct 29, 2022 this sequence version replaced XM_011245805.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.17984.1,
                                           SRR10223971.15641.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-652               AC087799.43        28265-28916
            653-2388            AC087799.43        29104-30839
            2389-2579           AC087799.43        124735-124925
            2580-2741           AC087799.43        135903-136064
            2742-2959           AC087799.43        136950-137167
            2960-3062           AC087799.43        141434-141536
            3063-3271           AC087799.43        144107-144315
            3272-3431           AC087799.43        149846-150005
            3432-3580           AC087799.43        151135-151283
            3581-3622           AC087799.43        153988-154029
            3623-7826           AC132575.3         133924-138127       c
FEATURES             Location/Qualifiers
     source          1..7826
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.42 cM"
     gene            1..7826
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /note="adenylate cyclase 9"
                     /db_xref="GeneID:11515"
                     /db_xref="MGI:MGI:108450"
     exon            1..652
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            653..2388
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     CDS             696..4814
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /EC_number="4.6.1.1"
                     /note="isoform 3 is encoded by transcript variant 3;
                     adenylate cyclase type 9; adenylyl cyclase 9; adenylyl
                     cyclase type 10; ATP pyrophosphate-lyase 9; adenylate
                     cyclase type IX"
                     /codon_start=1
                     /product="adenylate cyclase type 9 isoform 3"
                     /protein_id="NP_001400201.1"
                     /db_xref="GeneID:11515"
                     /db_xref="MGI:MGI:108450"
                     /translation="MASSPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNTHPK
                     HCKYSISSSCSSSGDSGGLPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSMNLEE
                     ACLERCFPQTQRRFRYALFYVGFACLLWSIYFAVHMKSKVIVMVVPALCFLVVCVGFF
                     LFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVWTPLSGRVDSSNHTLTATPADTCL
                     SQVGSFSICIEVLLLLYTVMQLPLYLSLFLGVVYSVLFETFGYHFRNEDCYPSPGPGA
                     LHWELLSRALLHVCIHAIGIHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMI
                     HSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEE
                     VSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEQTKCEKISTLGDCYYCVAG
                     CPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFD
                     VWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGRVIERLGQSVVADQLKGL
                     KTYLISGQRAKESHCSCAEALLSGFEVIDDSRESSGPRGQGTASPGSVSDLAQTVKTF
                     DNLKTCPSCGITFAPKSEAGAEGGTVQNGCQDEPKTSTKVTSSWLLFLSVPLLAHPPK
                     ASGGPNSKTQNGLLSPPAEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIR
                     EKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKT
                     FASATFSSLLDVFLSTTVFLILSITCFLKYGATATPPPPAALAVFGADLLLEVLSLIV
                     SIRMVFFLEDVMTCTKWLLEWIAGWLPRHCIGAILVSLPALAVYSHITSEFETNIHVT
                     MFTGSAVLVAVVHYCNFCQLSSWMRSSLATIVGAGLLLLLHISLCQDSSIVMSPLDSA
                     QNFSAQRNPCNSSVLQDGRRPASLIGKELILTFFLLLLLVWFLNREFEVSYRLHYHGD
                     VEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSE
                     FYEENYEGGKECYRVLNELIGDFDELLSKPDYNSIEKIKTIGATYMAASGLNTAQCQE
                     GGHPQEHLRILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYD
                     IWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYP
                     KCTDNGVVPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYSDKASLGSDDSTQA
                     KEARLSSKRSWREPVKAEERFPFGKAIEKDSCEDIGVEEASELSKLNVSKSV"
     exon            2389..2579
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            2580..2741
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            2742..2959
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            2960..3062
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            3063..3271
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            3272..3431
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            3432..3580
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            3581..3622
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     exon            3623..7826
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7805..7810
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /note="hexamer: ATTAAA"
     polyA_site      7826
                     /gene="Adcy9"
                     /gene_synonym="AC9; ACtp10; D16Wsu65e; mKIAA0520"
                     /note="major polyA site"
ORIGIN      
        1 gccggagatg gtggtggcgg cggctgcggc tgctactctt ccgacctgag gcagcggctg
       61 cgggagagcg ggcggcgggc gcagccgcag cggcatctgt agctcaggca gggcccctgg
      121 ggcgtgggcg cggcgtgcgg acgaccggcg tgctggccag ccggcgtcgc gggagtcagg
      181 ctctgcggca gcccgcacgg cggtctgtgg aggggcccgc gcagtgcccc gagctcggct
      241 ctgggccggg gtgcgttcgg ctgcgggcag caggccctgc tagaccggcc gctcggacgg
      301 gcggccctcg ggctcctcaa gctcgcgagc aggggcgcgg ggcagggtag cccgctggtg
      361 cttagccgca aggggacgga acgcggcagg agccgcaggt tggcccgcgc gctttgacgc
      421 accgggcgct gctgcggcag gatgaagcgc tgctcgcctc ccgagttgtt tttgcgaaag
      481 ctgctcccgg tgccccgagc gctcaaggtc tgaacttccc tctggagctg cagttggagt
      541 tgcacgggga gaggccacca gcgggcgacg gcgcccgagg ggagcgcagc gcagcgctgc
      601 cggggaccca agactcagcg cggccgcggc acgagaaccc tgggagcacc aggtgcccct
      661 gacctggtcg ggaaaggttc caagagctcg gcaacatggc ttcctcaccc caccagcagc
      721 tgctgcatca ccatagcacc gaggtgagct gcgactcaag cggagacagc aacagcgtga
      781 gggtcaagat caaccctaag cagctgtcct ccaacaccca cccgaagcac tgcaagtaca
      841 gcatctcctc cagctgtagc agctcgggag actcaggggg ccttccccgg agggttggcg
      901 gcgggggtcg cctgcgcaga cagaagaagc tgccccagct ttttgagagg gcctccagcc
      961 ggtggtggga ccccaaattc gactccatga acctggagga ggcctgcctg gagcgctgct
     1021 ttccgcagac ccagcgccgc ttccggtacg cactctttta tgtgggcttc gcctgccttc
     1081 tctggagcat ctatttcgct gtccacatga aatccaaagt gattgtcatg gtggtcccag
     1141 ctctgtgctt cctggtggtg tgtgtgggct ttttcctgtt tactttcacc aagctgtacg
     1201 cccggcatta tgcgtggacc tcgctggctc tcaccctgct ggtgttcgcc ctgaccctgg
     1261 ctgcgcagtt tcaggtttgg acacctctgt caggacgtgt tgacagctcc aatcatactc
     1321 tcacggccac tccggcggac acttgcttat ctcaagtagg aagcttctcc atatgcatcg
     1381 aagtgctcct tttgctctac acagtcatgc agttacctct gtacctgagc ttgtttttgg
     1441 gggtggtcta ttctgtcctt tttgagacct tcggctacca cttccgaaac gaagactgct
     1501 acccttctcc gggccctggg gccctgcact gggagctgct gagcagagcc ctgcttcacg
     1561 tgtgcattca cgctatcggg atccatctgt ttgtcatgtc tcaggtgagg tccaggagca
     1621 cctttctcaa ggtgggacaa tccattatgc acggcaaaga tctggaagta gagaaagccc
     1681 tgaaagagag gatgattcat tcagtgatgc caagaatcat agccgacgac ttaatgaaac
     1741 aaggggacga ggagagtgag aattccgtca agaggcatgc cacctccagt cccaagaaca
     1801 ggaagaagaa gtcctccata cagaaggcac cgatagcatt ccgccccttt aagatgcagc
     1861 agattgaaga agtcagtatt ttatttgcag acattgtggg tttcaccaag atgagcgcca
     1921 acaaatctgc gcatgccttg gtaggcctac tcaatgacct gttcggtcgc tttgaccgcc
     1981 tgtgtgagca gaccaagtgt gagaagatca gcactctggg ggactgttat tactgtgtgg
     2041 cagggtgtcc ggagccccgg gcagaccatg cctactgctg cattgaaatg ggcttaggca
     2101 tgataaaagc catcgagcag ttctgccagg agaagaaaga gatggtgaac atgcgtgttg
     2161 gggttcacac ggggactgtc ctgtgtggca tcctgggcat gaggaggttt aaatttgatg
     2221 tgtggtccaa cgatgtgaac ttggctaatc tcatggagca gctgggagtg gctggcaaag
     2281 ttcacatatc tgaggccact gcaaaatact tagacgacag gtatgaaatg gaagatggga
     2341 gagttattga gcgccttggg cagagtgtgg tggctgacca gttgaaaggt ttgaagacat
     2401 acctgatatc gggtcagaga gccaaggagt cccactgcag ctgtgcagag gccctgcttt
     2461 ctggctttga ggtcattgac gactcacggg agtcctcagg ccctagggga caggggacag
     2521 catcgccagg gagtgtcagt gatttggcgc agactgtcaa aacctttgat aaccttaaga
     2581 cttgcccttc ttgtggaatc acatttgctc ccaaatctga agctggtgca gaaggaggaa
     2641 ctgtgcaaaa tggctgtcaa gacgagccta agaccagcac caaggtaaca agctcatggc
     2701 tgttgttcct gtcagtacct ctcctggcgc atccacctaa ggcttctgga ggacccaact
     2761 ccaaaaccca gaatggactt ctgagccctc ctgcagagga gaagctcact aacagccaga
     2821 cctccctctg tgagatcctg caagagaagg gacggtgggc aggggtgagc ttggaccagt
     2881 cagccctcct cccgctcagg ttcaagaaca tccgtgagaa aactgatgcc cactttgttg
     2941 atgtcatcaa agaagacagc ctgatgaaag attatttctt caagccgccc atcaatcagt
     3001 tcagcctgaa cttcctggac caggagctgg agcgatcata tagaaccagc taccaggaag
     3061 aggtcataaa gaattctcct gtgaagacgt tcgccagtgc caccttcagc tcccttctgg
     3121 atgtgtttct gtcaaccacc gtgttcttga ttctctccat cacctgcttc ctaaagtatg
     3181 gagccaccgc cacccctccc ccaccggctg ccctggccgt ctttggtgca gacctgctgc
     3241 tggaggtgct ttccctcata gtgtccatca gaatggtgtt tttcctagag gatgtcatga
     3301 catgcacaaa gtggttgctg gaatggatcg ctggctggct ccctcgccac tgcattgggg
     3361 caatcttggt gtctcttcct gccctggctg tctattcaca catcacctct gagtttgaga
     3421 ccaacataca tgttaccatg ttcactggct ctgcggtgct ggtggccgtt gtgcactact
     3481 gtaacttctg ccagctcagc tcctggatga ggtcctccct tgccaccatc gtgggggctg
     3541 ggctgctgct tctgctccac atctccctgt gtcaggacag ttccattgtg atgtccccct
     3601 tggactcagc acagaatttc agtgcccaga ggaacccatg caacagctca gtgctgcagg
     3661 acggcaggag gccggccagc ctcataggca aggagcttat cctcaccttc ttcctcctgc
     3721 tcctcttggt ctggttcctg aaccgggagt tcgaggtcag ctaccggctg cactaccatg
     3781 gggatgtgga ggccgaccta caccgcacca agatccagag catgagagac caggctgact
     3841 ggctactgcg gaacatcatc ccctaccatg tggctgagca gctcaaggtc tctcagacct
     3901 actccaagaa ccatgacagc gggggagtca tctttgccag cattgtcaac ttcagtgaat
     3961 tctatgagga gaactatgag gggggcaagg agtgctaccg tgtcctcaac gagctgatcg
     4021 gtgacttcga tgagctcttg agcaagccgg actataatag catcgagaag atcaagacca
     4081 tcggggccac atacatggca gcctcagggc tgaacacggc ccagtgtcag gagggtggcc
     4141 acccacagga gcatctgcgt atcctcttcg agttcgccaa ggagatgatg cgcgtggtgg
     4201 atgacttcaa caacaatatg ttatggttca acttcaagct cagggtcggc tttaaccacg
     4261 gacccctcac agcaggtgtc ataggtacca ccaagctgct gtatgacatc tggggggaca
     4321 ccgtcaacat cgccagcagg atggacacca ctggtgtgga gtgccgtatc caggtgagcg
     4381 aagagagcta ccgtgtgctg agcaagatgg gttatgactt tgactaccga gggaccgtga
     4441 atgtcaaggg gaaagggcag atgaagacct acctttaccc aaagtgcacg gacaatggag
     4501 tggttcccca gcaccagctg tccatctccc cagacatccg agtccaggtg gacggcagca
     4561 ttgggcggtc tcccacagat gagattgcca acttggtgcc ttccgttcag tattcggaca
     4621 aggcttccct gggatctgat gatagcacac aggctaagga agctcgcctg tcctctaaga
     4681 ggtcctggag agagccagtc aaagcagagg aaaggtttcc atttggcaaa gccatagaaa
     4741 aggacagctg tgaagacata ggagtagaag aggccagtga actcagcaag ctcaatgtct
     4801 caaagagtgt gtgaggcagc gccgagagct gccaaggtgc tctgcgtgtc caaacacagt
     4861 aacatctgtg tcgataggct gttgtgctat ctagcacctc agtttctgtc cccagatgtg
     4921 gtgtcacgtg gtcatttcag cccgaatctc tgtgtggagc acagttattc agggttcatt
     4981 tccacccatt tcggttttcc tttacttgcg ttcctggaag ccttttcctg gaagcctgcc
     5041 cccagcccag ccaggggatc cagtcagcag cgtggaggga ttcaagtgcc ttcagggtct
     5101 ggccttgcgt ctggggctga ggccactggt ggaatcatgg ccctggggat tatttgactt
     5161 ctttaagaaa aaaaaaaaaa aaaggaaaaa aaaaagctgt ggttaaaata ccatttttat
     5221 tgccttttct cacaagtttt ttttttctca tacagtgttt tccagtttat tttttctata
     5281 tgtgtaatag tatttttcag tcacttggcc tttctaagca catccacgca cacatacttg
     5341 catttatgaa tctgacataa agtgccagta aactcatctg ggggaggggc tatagaaggg
     5401 agcagggctg gaagcaagcc ccctcctggc atctctaggg tacctgggcc cacattcctg
     5461 tggcccacaa atgggcttct ccgcctccaa cactgggcag tttcaggggc tcatctgcac
     5521 gcaggccaag atttcatatg ctcaccagac acaaagctta caaaccaggc ctcaggaatc
     5581 tcaaagccgt gttttcatcc cgaccccaca cagaagggtc ttccagccaa gagtgaagat
     5641 gtttgtctca gaagctgacc catttgaggg agatgtttaa ccatctgagg atgcatttat
     5701 ttatttattt atttatttat caaaacatgt gtattatggg gagggggcac tgggtagttt
     5761 tggtggaggg aagcagtcag ggagtgggca gggcagtttg caaaggacac agccgaccaa
     5821 tgacaagatg tccctctatg tttcatgtct catccactgt ggcccatggt gccacccagg
     5881 gtgctgttcc ctcttgtggg gatccagagt aaaactggct cggcgccagg tgggattctg
     5941 caaacctttt gtccgttcca cccactgttg gactgcacgg gctggcttgt ggtgggattt
     6001 aattctgttg gtcaattcaa actcttgaag ggggtttctt acggggcacc gagggacaga
     6061 gccatctgtt ttgccaaagg aaatgcagac agcctgtcac agatgaaatt tgagttcctg
     6121 gctgctaacc ttgcttgtaa ttaaattgtg ttcttccatg atgaatctca agttgatgct
     6181 ggaaggagct caagctacag ctgccccgcc accatcattt ttccaggtca tgctgatgtg
     6241 tagctcatga gacaactgaa gaccatctct gtgcctattg gaggtcttca tgccatgccc
     6301 tgtgtgtggt gtgttctttc actggtaaac ttcactgtat agctttcaca tctgagttaa
     6361 gcccggtttt cactcctccc tgaagatgga cagaacctgc ttatgctagc aaggtgacat
     6421 cttagcttta gtcagctact tccccagaga cacctgggat ggccacccat gcagcaaagc
     6481 catgccagga cccagagtat tcttagtgac tggaagattt cctgtcccag ttggctccct
     6541 gttggtcttc caactagaag aacagataag ttgtgacaat acctcttgct tctaaagaat
     6601 gtattcctgt acaatgccac agattttctt ttcttaagaa cactacctga ttctttcctt
     6661 gtgctaggga tgtagggcat gctggggtct cctgtcagta ttcaggtgtg ctcaactgac
     6721 cgagtattag gttgtcctcc acctccaggc tgcatcactt ggaggagcta gctagtggcc
     6781 ggggtttttg caatcttggt tcaagatgtg ctctgtcaag ttcatctctt ctcacacctt
     6841 ccctctcaaa ctctttcttt ctctgttaca aaggtatctg tgagtctttc ccagcccact
     6901 ccccaactct agacctccaa accaactgga gagaatcact aaccttgagc ggatgaccca
     6961 gttctgcatc gtgcaaatgg agccctagct gaagggcagt tcatacaaag tgcagtggtc
     7021 ttcaacaccc tgagccttcc tgaagaacca gtgcagacat tcttctttca gggtgcaagg
     7081 ccccttgggg cctttccagc tccctgcccc taagcatacc tcaacacaga accacaggat
     7141 ctctgcagca cacctgccgt gcagcttggt ctgttggcat tgaacaaaca gctgttgcta
     7201 gagacagttg ggcttccagg cagtggactg gagtgtccat caggtggcag tacttcttag
     7261 gaacctaggg caggaagcaa tacttcagaa ttgaatgtgt gtaaatagtt gctttgcatt
     7321 gcaattgctc tttccttctt ggccccagca cagatcagtt ttatacatct gtatgatcaa
     7381 gcacacataa ttttatccca cacaaatgaa cgtagagtgc tcgtcggtta taaaccctca
     7441 aacagcttga cgagccccac agatgtgcca cacctgtgca tggctccctc tgccctaact
     7501 tcactcctgg gatgcacctg cacatttgca catgacacag cgagccaaag gcagtgtgcg
     7561 accatcacct gggctgcagt cacttgtagt atccaaagat aagtctgcat ttgaatttct
     7621 tgattttcaa ggtaagcatt ttttttgggg ggggggctgg ttgttttgaa aatcgcatca
     7681 tgcctagaac ctgaaattat attagtaaga accaattgtt tgtatttcca tgttttcctt
     7741 tgctctgctc tttttaaatt gttaattcta agaatttcaa attgcatcca ctgaaaagaa
     7801 ggatattaaa atgttctaaa acgtaa
//
