LOCUS       NM_138305               4348 bp    mRNA    linear   ROD 31-MAY-2023
DEFINITION  Mus musculus adenylate cyclase 3 (Adcy3), transcript variant 1,
            mRNA.
ACCESSION   NM_138305
VERSION     NM_138305.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4348)
  AUTHORS   Bashford AL and Subramanian V.
  TITLE     Hippocampals neurogenesis is impaired in mice with a deletion in
            the coiled coil domain of Talpid3-implications for Joubert syndrome
  JOURNAL   Hum Mol Genet 31 (19), 3245-3265 (2022)
   PUBMED   35470378
REFERENCE   2  (bases 1 to 4348)
  AUTHORS   Mytlis A, Kumar V, Qiu T, Deis R, Hart N, Levy K, Masek M, Shawahny
            A, Ahmad A, Eitan H, Nather F, Adar-Levor S, Birnbaum RY, Elia N,
            Bachmann-Gagescu R, Roy S and Elkouby YM.
  TITLE     Control of meiotic chromosomal bouquet and germ cell morphogenesis
            by the zygotene cilium
  JOURNAL   Science 376 (6599), eabh3104 (2022)
   PUBMED   35549308
REFERENCE   3  (bases 1 to 4348)
  AUTHORS   Fabregat M, Nino-Rivero S, Pose S, Cardenas-Rodriguez M, Bresque M,
            Hernandez K, Prieto-Echague V, Schlapp G, Crispo M, Lagos P, Lago
            N, Escande C, Irigoin F and Badano JL.
  TITLE     Generation and characterization of Ccdc28b mutant mice links the
            Bardet-Biedl associated gene with mild social behavioral phenotypes
  JOURNAL   PLoS Genet 18 (6), e1009896 (2022)
   PUBMED   35653384
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4348)
  AUTHORS   Chen T, Zhou Y, Liu X, Liu Y, Yuan J and Wang Z.
  TITLE     Adenylyl cyclase 3 deficiency results in dysfunction of
            blood-testis barrier during mouse spermiogenesis
  JOURNAL   Theriogenology 180, 40-52 (2022)
   PUBMED   34953349
  REMARK    GeneRIF: Adenylyl cyclase 3 deficiency results in dysfunction of
            blood-testis barrier during mouse spermiogenesis.
REFERENCE   5  (bases 1 to 4348)
  AUTHORS   Orecchioni M, Kobiyama K, Winkels H, Ghosheh Y, McArdle S, Mikulski
            Z, Kiosses WB, Fan Z, Wen L, Jung Y, Roy P, Ali AJ, Miyamoto Y,
            Mangan M, Makings J, Wang Z, Denn A, Vallejo J, Owens M, Durant CP,
            Braumann S, Mader N, Li L, Matsunami H, Eckmann L, Latz E, Wang Z,
            Hazen SL and Ley K.
  TITLE     Olfactory receptor 2 in vascular macrophages drives atherosclerosis
            by NLRP3-dependent IL-1 production
  JOURNAL   Science 375 (6577), 214-221 (2022)
   PUBMED   35025664
REFERENCE   6  (bases 1 to 4348)
  AUTHORS   Kobayakawa K, Hayashi R, Morita K, Miyamichi K, Oka Y, Tsuboi A and
            Sakano H.
  TITLE     Stomatin-related olfactory protein, SRO, specifically expressed in
            the murine olfactory sensory neurons
  JOURNAL   J Neurosci 22 (14), 5931-5937 (2002)
   PUBMED   12122055
REFERENCE   7  (bases 1 to 4348)
  AUTHORS   Meneray MA and Lallier TE.
  TITLE     Differential expression of adenylyl cyclase mRNAs in lacrimal
            glands of NZB/NZW and NOD pre-autoimmune mice
  JOURNAL   Adv Exp Med Biol 506 (Pt A), 41-49 (2002)
   PUBMED   12613887
REFERENCE   8  (bases 1 to 4348)
  AUTHORS   Piao Y, Ko NT, Lim MK and Ko MS.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   9  (bases 1 to 4348)
  AUTHORS   Wong ST, Trinh K, Hacker B, Chan GC, Lowe G, Gaggar A, Xia Z, Gold
            GH and Storm DR.
  TITLE     Disruption of the type III adenylyl cyclase gene leads to
            peripheral and behavioral anosmia in transgenic mice
  JOURNAL   Neuron 27 (3), 487-497 (2000)
   PUBMED   11055432
REFERENCE   10 (bases 1 to 4348)
  AUTHORS   Edelhoff S, Villacres EC, Storm DR and Disteche CM.
  TITLE     Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in
            mouse
  JOURNAL   Mamm Genome 6 (2), 111-113 (1995)
   PUBMED   7766992
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK122298.1 and BQ442923.1.
            
            [WARNING] On Jun 22, 2023 this sequence was replaced by
            NM_138305.4.
            
            On Apr 18, 2009 this sequence version replaced NM_138305.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF458089.1, SRR7974084.28471.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2668              AK122298.1         295-2962
            2669-2671           BQ442923.1         343-345
            2672-4348           AK122298.1         2963-4639
FEATURES             Location/Qualifiers
     source          1..4348
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12"
     gene            1..4348
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /note="adenylate cyclase 3"
                     /db_xref="GeneID:104111"
                     /db_xref="MGI:MGI:99675"
     exon            1..848
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            849..998
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1129
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1241
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1369
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1528
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1703
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..1832
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..1975
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..2137
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2138..2225
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2226..2342
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2343..2602
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2603..2668
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2669..2753
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2754..2912
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            2913..3059
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            3060..3179
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            3180..3303
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            3304..3428
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
     exon            3429..4348
                     /gene="Adcy3"
                     /gene_synonym="AC3; ACIII; mKIAA0511"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgttcggtg ccacctgtgt cctgggaacc cactaagcat tccagctcca gttggacgcc
       61 cttcattcat aaccaagagg aacctccccg ccttccccgg gtcttacgaa gccctggtga
      121 agtggcttga cctgcaggtc tcccttcctc attagaaaca gccagcagcc aacatgccga
      181 ggaaccaggg cttctcggat cccgagtact cggcagagta ctcagctgaa tactcggtca
      241 gcctgccctc tgaccccgac cgcggggtcg gccggaccca tgaaatttct gtgcggaact
      301 cggggtcctg cctgtgcctg cctcgcttta tgcggctgac cttcgtgcct gagtccttgg
      361 agaacctcta ccagacctac ttcaaaaggc agcgccatga gaccctgctg gtgctggtgg
      421 tctttgcggc cctctttgac tgctacgtgg tagtgatgtg cgcggtggtc ttctccagcg
      481 acaagctggc gcccctcatg gtggcaggct tcggtctggt gttggacatc atccttttcg
      541 tgctctgtaa aaaggggctg ctcccggacc gagtgagccg caaagtggta ccctacctgc
      601 tgtggctgct catctcggcc cagatcttct cctacctggg cctgaacttt tcacgggccc
      661 acgcagccag tgacactgtg ggttggcagg ctttctttgt cttctccttc ttcataacgc
      721 tgcccctcag cctcagcccc atcgtgatca tctctgtggt ctcctgtgtt gtgcacacgc
      781 ttgtgttggg ggtcactgtg gcccagcagc agcaggatga gctggaaggg atgcagctgc
      841 tgagggagat cctggccaac gtcttcctct acctgtgtgc tatcatcgtg ggcatcatgt
      901 cctactacat ggcagaccgc aagcaccgca aggccttcct ggaggcccgc cagtcactgg
      961 aggtgaagat gaatctggag gagcagagcc agcagcagga aaaccttatg ctttccatcc
     1021 tgcccaagca cgtggctgac gagatgctga aggacatgaa gaaggacgag agccagaagg
     1081 accagcagca gttcaatacc atgtacatgt accggcacga gaatgtcagc atcctgtttg
     1141 cagatattgt gggctttacc cagctgtcct ctgcttgcag tgcccaggag ctcgtgaagt
     1201 tactcaacga gctcttcgcc cgctttgaca agctggcagc caaataccac cagctgagga
     1261 tcaagatcct aggcgactgt tactactgca tctgcggctt gcctgactac cgggaggacc
     1321 atgccgtgtg ctccatcctt atggggcttg ccatggtaga ggccatctcg tacgtgcggg
     1381 agaagaccaa gactggagtg gacatgcgtg tgggagtgca cacaggcact gtcctaggcg
     1441 gtgtcctggg ccagaagcgc tggcagtatg atgtatggtc tactgatgtc accgtggcaa
     1501 acaagatgga ggctggtggc atcccagggc gcgtgcacat ttcccagagc accatggact
     1561 gcctgaaggg ggagtttgat gtggagcctg gtgatggggg cagtcgctgc gactacctag
     1621 atgagaaggg catcgaaacc tacctcatca ttgcctccaa gccagaggtg aagaaaacag
     1681 cccaaaatgg cctcaacggc tcggccgtgc caaacggagc gccggcatcc tccaaaccca
     1741 gctcccctgc cctcatcgag accaaggagc ccaatggaag tgcccatgcc agcggctcca
     1801 catcagagga ggctgaagaa caggaggccc aggctgacaa cccctcgttc cccaaccccc
     1861 gccgcaggct gcgcctccag gacctggcgg accgtgtggt ggacgcctct gaggatgagc
     1921 acgaactgaa ccagctgctt aatgaggccc tgctggagcg ggagtccgcc caggtggtaa
     1981 agaagagaaa cacattcctc ctgaccatga ggttcatgga cccagagatg gaaacacgct
     2041 actcggtgga gaaggagaag cagagcgggg ctgccttcag ctgctcctgt gtggtcctct
     2101 tctgcacggc catggtggag atactcattg acccctggct gatgacaaac tatgtgacct
     2161 ttgtggttgg ggaggttctg ctcctgatcc tgaccatctg ctcgatggct gccatctttc
     2221 ccaggtcatt tcccaagaag cttgtggcct tctcatcttg gattgaccgg acccgctggg
     2281 caaggaacac ctgggccatg ttagccatct tcattctggt tatggccaat gttgtggaca
     2341 tgctcagctg tctccagtac tacatgggac cttacaacat gacagctggg atggagctgg
     2401 acggcggctg catggagaac cccaagtact acaactacgt agctgtgctg tcgctcatcg
     2461 ccaccatcat gctggtgcag gtcagccaca tggtgaagct gacgctcatg ctgctcgtca
     2521 caggcgccgt gactgccctc aacctgtacg cctggtgtcc tgtctttgat gaatacgacc
     2581 acaagcgctt tcaggaaaag gactctccta tggtggcctt agagaagatg caggtacttg
     2641 ccacccctgg gctcaatggc actgacagca ggctgcccct ggtgccttcc aagtactcca
     2701 tgactgtgat gatgttcgtc atgatgctga gcttttacta cttctcgcgc cacgtggaaa
     2761 aactggcccg aacactgttc ttgtggaaga ttgaggtcca tgaccagaaa gaacgtgtct
     2821 acgagatgcg ccgatggaac gaggccttgg tcaccaacat gttgcctgag catgttgcac
     2881 gccattttct ggggtccaag aagagagatg aggagctgta cagccagtct tatgacgaga
     2941 ttggagtcat gtttgcctcc ttgcccaact ttgctgactt ctacactgag gagagcatca
     3001 acaacggcgg catcgagtgt ctacgcttcc tcaatgagat catctctgat tttgactctc
     3061 tcctggacaa tcccaaattc cgggtcatca ccaagatcaa aactattggc agcacctata
     3121 tggcagcttc aggagtcaca ccagatgtca acaccaatgg ctttacaagc tccagcaagg
     3181 aggagaagtc agacaaggag cgctggcagc acctggctga cctggctgac tttgcattag
     3241 ccatgaagga cacgctcaca aacatcaaca accagtcatt caacaacttc atgttgcgca
     3301 taggcatgaa caaaggaggg gttctggctg gcgtcattgg agcccggaaa ccacactatg
     3361 acatctgggg caatacggtc aatgtggcca gcaggatgga atccacagga gtcatgggca
     3421 acatccaggt ggtagaagag acgcaggtca tccttcgaga gtacggcttc cgctttgtga
     3481 ggcgaggtcc catctttgtg aaaggcaaag gggagcttct gacctttttc ttgaaggggc
     3541 gggacaggcc agctgccttc cccaatggct cctctgttac actgccccac caagtggtgg
     3601 acaacccctg agcgacctct ggctccacag tggtccacat aggaaggggg atttttttgg
     3661 aagcagtgaa aagctttggg aaaggacaaa tgaccaagtc ctggtgttcc caattattga
     3721 agcgcacatt ccatagactt taggtttcag atttcctcca gccttcctgt gtggatgtga
     3781 gctctgaggg tggctattcc tactcctcag tgagcctgta gcttccccaa agcaggagtc
     3841 ttaggcatag tactggagca gcctttccag agcctttgtt ccagctcagc ccttcacccc
     3901 tagagaggcc atggccactg tgagcaggat gccagccgag gcggaacgaa gctgcctgtg
     3961 ctgggggcgg ggagctccgg ttgggctcag ggctgaggag gctctgcacc cggctgctcc
     4021 ttcctgtctg gttaggtcaa tggcccttac cccacccact gttcctgata atcttgaaag
     4081 gttcttctgg aacccgtgtc accttagtca cgagagcaga aagtgcaata tttcctttca
     4141 cctggttggg aaggggggtt atttctgaaa gaaaaatata taaacagatc ttctacattt
     4201 atatttttaa cctgttcaaa aaacaacttt ccaatattgc cttgtcttct gagctcttgc
     4261 tacagtcgcc tttgctactg ctttaacaaa gaatctgcag gtgttgataa agaacaggac
     4321 tgttttatta aaagctttac tcaacttg
//
