LOCUS       NM_013925               3169 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus adenosine deaminase, tRNA-specific 1 (Adat1),
            transcript variant 1, mRNA.
ACCESSION   NM_013925
VERSION     NM_013925.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3169)
  AUTHORS   Maas,S., Kim,Y.G. and Rich,A.
  TITLE     Genomic clustering of tRNA-specific adenosine deaminase ADAT1 and
            two tRNA synthetases
  JOURNAL   Mamm Genome 12 (5), 387-393 (2001)
   PUBMED   11331948
REFERENCE   2  (bases 1 to 3169)
  AUTHORS   Maas,S., Kim,Y.G. and Rich,A.
  TITLE     Sequence, genomic organization and functional expression of the
            murine tRNA-specific adenosine deaminase ADAT1
  JOURNAL   Gene 243 (1-2), 59-66 (2000)
   PUBMED   10675613
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK082399.1 and AC115914.6.
            
            On Oct 21, 2017 this sequence version replaced NM_013925.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK082399.1, AK039699.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2359              AK082399.1         2-2360
            2360-3169           AC115914.6         4456-5265
FEATURES             Location/Qualifiers
     source          1..3169
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 58.23 cM"
     gene            1..3169
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /note="adenosine deaminase, tRNA-specific 1"
                     /db_xref="GeneID:30947"
                     /db_xref="MGI:MGI:1353631"
     exon            1..122
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            123..330
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..1661
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /EC_number="3.5.4.34"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tRNA-specific adenosine deaminase 1; tRNA-specific
                     adenosine-37 deaminase"
                     /codon_start=1
                     /product="tRNA-specific adenosine deaminase 1 isoform 1"
                     /protein_id="NP_038953.1"
                     /db_xref="CCDS:CCDS22684.1"
                     /db_xref="GeneID:30947"
                     /db_xref="MGI:MGI:1353631"
                     /translation="MWTADEIAQLCYAHYNVRLPKQGKPEPNREWTLLAAVVKIQASA
                     NQACDIPEKEVQVTKEVVSMGTGTKCIGQSKMRESGDILNDSHAEIIARRSFQRYLLH
                     QLHLAAVLKEDSIFVPGTQRGLWRLRPDLSFVFFSSHTPCGDASIIPMLEFEEQPCCP
                     VIRSWANNSPVQETENLEDSKDKRNCEDPASPVAKKMRLGTPARSLSNCVAHHGTQES
                     GPVKPDVSSSDLTKEEPDAANGIASGSFRVVDVYRTGAKCVPGETGDLREPGAAYHQV
                     GLLRVKPGRGDRTCSMSCSDKMARWNVLGCQGALLMHFLEKPIYLSAVVIGKCPYSQE
                     AMRRALTGRCEETLVLPRGFGVQELEIQQSGLLFEQSRCAVHRKRGDSPGRLVPCGAA
                     ISWSAVPQQPLDVTANGFPQGTTKKEIGSPRARSRISKVELFRSFQKLLSSIADDEQP
                     DSIRVTKKLDTYQEYKDAASAYQEAWGALRRIQPFASWIRNPPDYHQFK"
     exon            331..399
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            400..454
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            455..585
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            586..1189
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1335
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1435
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1522
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..3169
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3137..3142
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /note="hexamer: TATAAA"
     regulatory      3150..3155
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /note="hexamer: ATTAAA"
     polyA_site      3155
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
                     /note="major polyA site"
     polyA_site      3168
                     /gene="Adat1"
                     /gene_synonym="MMADAT1"
ORIGIN      
        1 cctctagggc gtcacttccg ctgcgcaacc tggttaaacg agcgtggcgg tagaggggca
       61 tcgcgtggag gttgcggcgc gtggataata gggtgtgagg gactccggat cggcgtctcg
      121 ggatttggct ttctatagtg gcctcagctc cagctccacc tatgtggacc gcggatgaga
      181 tcgctcagct gtgctatgca cactataacg tcagactgcc caagcagggg aagcctgagc
      241 caaatcgtga gtggaccttg ctggcagctg tggtgaagat tcaggcttca gctaaccaag
      301 cttgtgacat ccctgagaag gaagtgcaag tgacaaagga agttgtctca atgggaacag
      361 gaacaaaatg cataggccag tccaagatgc gagagagcgg ggacatcctc aatgacagcc
      421 atgctgagat catagccaga aggagtttcc agagatacct tctccatcag ctccatttgg
      481 cagccgtcct gaaagaggat agcatctttg ttccagggac ccaaagagga ctgtggaggc
      541 tcagacctga cctgtcgttt gtgtttttct ctagccacac accctgtggg gatgcctcca
      601 tcatcccgat gctcgagttt gaagaacagc cttgctgtcc tgtcatcaga agttgggcca
      661 acaactcacc tgtacaagag actgagaatc tagaggattc taaagataaa aggaactgtg
      721 aagatcccgc cagtcctgta gccaagaaga tgaggctggg aacacctgcc aggtcactct
      781 ccaattgtgt agctcaccat gggacccagg aaagtggtcc agtcaaacca gatgtcagca
      841 gctctgatct caccaaggag gaaccagatg ctgccaatgg aatagcttca ggtagcttca
      901 gagtggtgga tgtgtacagg acgggagcca agtgtgttcc tggagaaact ggagacttga
      961 gagagccagg tgctgcctac caccaggtgg ggctacttcg tgtaaaacct ggcaggggag
     1021 acaggacatg ctccatgtcc tgcagtgaca agatggcaag gtggaatgtc ctcggatgcc
     1081 agggcgcact gctgatgcac ttcctggaga agcctatcta cctgtcagct gtggtcatcg
     1141 ggaagtgccc gtacagccag gaagccatga ggagagcatt gactggcagg tgtgaggaaa
     1201 ccttggtttt acccagaggc tttggagttc aagaactgga aatacagcag tcgggtttac
     1261 tgtttgaaca gagccgctgt gcggtgcaca ggaaaagagg tgacagtcca ggccgactcg
     1321 tcccctgtgg ggcagctatc agctggagcg ctgtccctca gcagcccttg gatgttacag
     1381 ccaatggttt tccacaggga acaacaaaga aagagattgg aagccctagg gccagatccc
     1441 gaatcagcaa ggtggaactc tttagatcat tccagaagct gctgagcagc attgcagatg
     1501 acgagcagcc agactccatc agggtaacga agaagctgga cacctatcag gagtacaagg
     1561 atgctgcgtc cgcctaccag gaagcctggg gtgccctccg caggatacag ccgtttgcgt
     1621 cctggatcag aaacccaccc gactaccacc aatttaaatg aactcttgct ggtatcagga
     1681 cccttcgtat cggtctgcct ctcccttcat gctgaacgaa cctctgcttt tctggtggtt
     1741 aaatcccagg agaatgagct gccttctccc agagcgctcg ctgcacctct ctggtgtcat
     1801 aaatggaccg cagaacctca gcaatctata cttgactgga gcagctccgt gctaaaatag
     1861 cctctcagta atgctcttga tggctgcctt caattgtgtt ttattggttc tttaaaatac
     1921 agcatcagat gcttttaaag tagcctgcag cagctctggt gtagatctcc ttacattgat
     1981 tcagcaagga cgcattgggc tgaaatcatc ttagggtgct ggaagcttta tagcctctcc
     2041 cggactcatg aaaaccatgt atttcctgtt tgcagccttc ctttgtaacc atcatcactt
     2101 cccagtcctc agcaactaga catggttgga gttagcttta ccatcaggct cagcacagga
     2161 ctagcctcgg aaagctctgt tctcagactt accaagaaag gttggttggt ttgggtttgg
     2221 gtttgggttt tggttttgag acagtctcac tttgaagcca ccatcattcc ccacccctct
     2281 ttctctttct ctcctttccc tttccccctt cccctccccc tcccttctac cttttgcttg
     2341 agaccggatc cctctctcta tagcccagcc tggccttgaa ctcaacatga agccaagggt
     2401 gaccttgaac tctgatcttc ccacctctgc ctctaagtgt cacctcaaac tttgcttcct
     2461 ggattctctt ctgagcaatg tcatgaggtc cactatagtc ttgtaactgc cagtagccac
     2521 cgtcttttcc taccacacag agacagccag ccaagaatga aggctccagc ctgcacaaaa
     2581 ccacatgagg caaatgcctg gtttgattgt ctttagtgtc tttatctgtg tgggccacac
     2641 tgtcgaggtg tgtgtgtgtg ggccacactg tcacggtggg ggggggggca cactgtcacg
     2701 gtgtgtgtgt ggcagtaagc agctgtatca gctgagcaat cttaccaggt tcctgttctg
     2761 actaaattgt tttcttttta actcagttcc caaatgcctt aatttcctac aacaaatcag
     2821 caaacgacgt agcagctaac cctgtttaac tgtcacctag gagagagcac tcagcttatt
     2881 cccacctgga agcagaagct ctgcttgcta ctcaatgtca ctgtggttta tagtgttttg
     2941 ttttgttttg ctttgctttg ctttgctttg ctttgttttt ccacacaggg tttctctgtg
     3001 tagctctggc tatcctggaa ctcactttgt agaccgggct ggcctcaaat gcagagatct
     3061 gcctgcctct gcctcctgag tgctgagatt aaagttgtgt gccaccatgc agtgttcttt
     3121 tatgagattt ttatattata aagacttgaa ttaaatgtga agtagtaac
//
