LOCUS       NM_001368621            7830 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus ADAMTS-like 1 (Adamtsl1), transcript variant 3, mRNA.
ACCESSION   NM_001368621
VERSION     NM_001368621.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7830)
  AUTHORS   Naba,A., Clauser,K.R., Mani,D.R., Carr,S.A. and Hynes,R.O.
  TITLE     Quantitative proteomic profiling of the extracellular matrix of
            pancreatic islets during the angiogenic switch and insulinoma
            progression
  JOURNAL   Sci Rep 7, 40495 (2017)
   PUBMED   28071719
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7830)
  AUTHORS   Naba,A., Clauser,K.R., Hoersch,S., Liu,H., Carr,S.A. and Hynes,R.O.
  TITLE     The matrisome: in silico definition and in vivo characterization by
            proteomics of normal and tumor extracellular matrices
  JOURNAL   Mol Cell Proteomics 11 (4), M111.014647 (2012)
   PUBMED   22159717
REFERENCE   3  (bases 1 to 7830)
  AUTHORS   Du,J., Takeuchi,H., Leonhard-Melief,C., Shroyer,K.R., Dlugosz,M.,
            Haltiwanger,R.S. and Holdener,B.C.
  TITLE     O-fucosylation of thrombospondin type 1 repeats restricts
            epithelial to mesenchymal transition (EMT) and maintains epiblast
            pluripotency during mouse gastrulation
  JOURNAL   Dev Biol 346 (1), 25-38 (2010)
   PUBMED   20637190
REFERENCE   4  (bases 1 to 7830)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   5  (bases 1 to 7830)
  AUTHORS   Hall,N.G., Klenotic,P., Anand-Apte,B. and Apte,S.S.
  TITLE     ADAMTSL-3/punctin-2, a novel glycoprotein in extracellular matrix
            related to the ADAMTS family of metalloproteases
  JOURNAL   Matrix Biol 22 (6), 501-510 (2003)
   PUBMED   14667842
REFERENCE   6  (bases 1 to 7830)
  AUTHORS   Hirohata,S., Wang,L.W., Miyagi,M., Yan,L., Seldin,M.F., Keene,D.R.,
            Crabb,J.W. and Apte,S.S.
  TITLE     Punctin, a novel ADAMTS-like molecule, ADAMTSL-1, in extracellular
            matrix
  JOURNAL   J Biol Chem 277 (14), 12182-12189 (2002)
   PUBMED   11805097
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772130.15, AL807242.7 and AL824705.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AL772130.15        28521-28666
            147-274             AL772130.15        62255-62382
            275-320             AL807242.7         14956-15001
            321-557             AL807242.7         60774-61010
            558-684             AL807242.7         103415-103541
            685-759             AL807242.7         116764-116838
            760-917             AL807242.7         121055-121212
            918-1029            AL807242.7         132082-132193
            1030-1168           AL807242.7         136692-136830
            1169-1219           AL807242.7         147856-147906
            1220-1424           AL807242.7         152110-152314
            1425-1572           AL807242.7         153902-154049
            1573-1657           AL807242.7         156895-156979
            1658-1959           AL807242.7         181010-181311
            1960-2089           AL807242.7         193858-193987
            2090-2300           AL824705.5         14352-14562
            2301-2480           AL824705.5         29231-29410
            2481-2634           AL824705.5         33458-33611
            2635-3760           AL824705.5         34423-35548
            3761-3888           AL824705.5         48728-48855
            3889-4017           AL824705.5         67245-67373
            4018-4221           AL824705.5         77857-78060
            4222-4356           AL824705.5         80807-80941
            4357-4569           AL824705.5         105980-106192
            4570-4750           AL824705.5         107864-108044
            4751-4958           AL824705.5         110865-111072
            4959-5068           AL824705.5         115750-115859
            5069-5289           AL824705.5         116553-116773
            5290-7830           AL824705.5         118235-120775
FEATURES             Location/Qualifiers
     source          1..7830
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 40.32 cM"
     gene            1..7830
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /note="ADAMTS-like 1"
                     /db_xref="GeneID:77739"
                     /db_xref="MGI:MGI:1924989"
     exon            1..146
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..5396
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /note="isoform 3 precursor is encoded by transcript
                     variant 3; ADAMTS-like protein 1; punctin-1"
                     /codon_start=1
                     /product="ADAMTS-like protein 1 isoform 3 precursor"
                     /protein_id="NP_001355550.1"
                     /db_xref="GeneID:77739"
                     /db_xref="MGI:MGI:1924989"
                     /translation="MECCRRAAPGTPLLVLAFLLLSSRTARSEEDREGLWDAWGPWSE
                     CSRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKYH
                     GQLYEWLPVSNDPDNPCSLKCQAKGTSLVVELAPKVLDGTRCYTESLDMCISGLCQIV
                     GCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSASKSDDTVVAIPYGSRHIRLV
                     LKGPDHLYLETKTLQGTKGENSLSSTGIFLVDNSTVDFQKLPDKEILRMTGPLTADFI
                     IKIHDLGPADSTVQFIFYQPIIHRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVA
                     DQYCHYYPENVKPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSC
                     GGGIQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPVVQPCNIFDCPKWLAQEWSPCTV
                     TCGQGLRYRVVLCIDHRGMHTGGCSAKTKPHIKEECIIPTPCYKPREKLPIEAKLPWF
                     KQAQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIIRCQVLLPFSQSVADLPADE
                     CEGPKPASQRACYAGPCNGETPEFNPDNGDGLLGGLQDLDELYDWEYEGFTKCSESCG
                     GGVQEAVVSCLNKQTRELADENLCVTSRRPPQLLKSCNLDPCPARWEIGKWSPCSLTC
                     GVGLQTRDVVCSHLLSREMNEVVVLADELCHHPKPSTVQACNRFNCPPAWYPAQWQLC
                     SRTCGGGIQKRDVLCKQRMADGSFLELPETFCSASKPTSHQGCKKDDCPSEWLLSEWS
                     ECSVSCGEGTQTRSAICQRVLKTGVSTVVNSTLCPPLPFSSSIRPCMLATCARPGRPS
                     TKHSPHIAAARNIYIQTRRQRKLHFVVGGFAYLLPKTTVVLRCPTRRFRKPLITWEKD
                     GQHSISSAHVTVAPFGYLKIHRLKPSDAGIYTCSAGPAREQFVIKLIGGNRKLVARPL
                     SLWSEEEEALQVRKTNPKEALQTHKHQNGIFSNGSKAEKRGLTADPGNRYDDIVSRLL
                     EQGGWPGELLASWEVQDSAERNASSEEDPNAEQALLHLPFTMVAEQKRLDDILRNLSQ
                     QPEELRDLYSKHLVAQLAQDIFRSHLENQDLLPKPSEQRFPPMAVPAHKHVSGFSSSL
                     RSSSGEAGGGSRRPHRKPAILRKISAAQQLSASEVVTHLGQTVALASGTLSVLLHCEA
                     VGNPRPTIHWTRNGEAVQFSDRILLQPDDSLQILAPVEADVGFYTCNATNALGYDSVS
                     IAVTLAGKPLVKTSRMTVLNTEKPTVTVDIGGTVRTVRGVNVTINCQVAGVPEAEVTW
                     FRNKSKLGSSHHLHEGSSHHLHEGSLLLTDVSFSDQGLYSCRAANLHGEQTESTQLLI
                     LDPPQVPTQLEDIRALLLATGPNLPSVLMSPLGTQLVLDPGNSALLGCPIKGHPTPNI
                     TWFQNGQPIATAPGLTHHIWGAGQILRVANLSGGPQGEFSCLAQNEAGTLLQKASLVI
                     QDYWWSVDRLATCSASCGNRGIHQPRLRCLLNTTEVDPEHCTGKPRPAVQPVACNRRD
                     CPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCSQLAKRPVDTQAC
                     NQQLCVEWAFSSWGQCNGPCIGPRLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQN
                     CWSEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHVRTNKAVPEHLCSWGPRPANWQ
                     RCNVTPCENTECRDTTRYCEKVRQLKLCQLGQFRSRCCGTCGKA"
     exon            147..274
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            275..320
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            321..557
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            558..684
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            685..759
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            760..917
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1029
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1168
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1219
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1424
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1572
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1657
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1959
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2089
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2300
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2480
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2481..2634
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2635..3760
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3761..3888
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            3889..4017
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4018..4221
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4222..4356
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4357..4569
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4570..4750
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4751..4958
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            4959..5068
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5069..5289
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
     exon            5290..7830
                     /gene="Adamtsl1"
                     /gene_synonym="5930437A14Rik; 6720426B09Rik; ADAMTSL-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcactggat gtgacagcag cgggcagagg agcacttagc agcttattca gtgtccgatt
       61 cggattccgg caaagatcca agtatggaat gctgccgtcg ggcagctcct ggcacaccgc
      121 tgctcgttct ggctttccta ctcctgagtt ccaggactgc acgctcagag gaagaccgtg
      181 aaggcctctg ggatgcctgg ggcccttgga gcgagtgttc cagaacctgt ggtgggggtg
      241 cctcctattc cctgagacgc tgcctgagca gcaagagctg tgaagggaga aatattcgat
      301 atagaacatg cagtaatgtg gactgcccac cagaagcagg tgatttccga gctcaacagt
      361 gttctgctca taacgacgtc aagtaccatg gacagcttta tgaatggctt cctgtatcta
      421 atgaccccga caatccatgc tcactcaagt gccaagcaaa aggaaccagc ctggttgtgg
      481 aactagcacc gaaggtctta gatggtacgc gatgctatac agaatcactg gatatgtgca
      541 tcagcggcct atgccaaatt gttggctgtg atcaccagct ggggagcact gtcaaagagg
      601 ataactgtgg agtgtgcaac ggagatggct caacgtgccg gctggtccga gggcagtata
      661 aatctcagct ctctgcaagt aaatcggatg acaccgtggt cgccattcct tacggcagca
      721 gacacatccg ccttgtctta aaagggccag atcatttgta tctggagacc aagaccctcc
      781 agggaactaa aggtgaaaat agtctgagct ctacaggcat tttccttgtg gacaattcta
      841 cagtggactt ccagaaactt ccagacaaag agatactgag gatgactggg ccactgacag
      901 cagatttcat catcaagatc catgacttgg gacctgcaga cagcaccgtc cagttcatct
      961 tctaccagcc catcatccac cgatggaggg aaacagactt ctttccttgc tcagcaacgt
     1021 gtggtggagg ctaccagctg acgtctgccg agtgctatga tctacggagt aaccgtgtgg
     1081 tggccgacca gtactgtcac tactaccccg agaacgtcaa gcccaaaccc aagcttcagg
     1141 agtgcaactt ggatccttgt ccagccagtg acggatacaa gcagatcatg ccttatgacc
     1201 tctaccatcc ccttcctcgg tgggaggcca ccccgtggac cgcgtgctcc tcctcatgtg
     1261 gggggggcat ccagagccgg gcagtttcct gtgtggagga ggacatccag gggcatgtca
     1321 cttcagtgga agagtggaaa tgcatgtaca ccccaaagat gccagtcgtg cagccctgca
     1381 acatttttga ctgccctaaa tggctggcac aggagtggtc tccgtgcaca gtgacctgtg
     1441 gccagggcct cagataccgc gtggtactct gcattgacca ccgaggaatg cacacaggag
     1501 gctgcagtgc taaaacaaag ccccacataa aagaagaatg catcattccc acaccgtgct
     1561 acaagcccag agagaaactt ccaatagagg ccaagctgcc atggttcaag caagcccagg
     1621 agctagagga aggagctgca gtgtctgaag agccttcgtt catcccagaa gcttggtcgg
     1681 cctgtactgt cacctgtggc gtggggacac aggtgcgaat aataagatgc caggtgctcc
     1741 tgcctttctc tcagtctgtg gctgacctgc ctgcggatga atgcgaaggg cctaagccag
     1801 catcgcaacg tgcctgttat gcgggaccgt gcaacgggga aactccggaa tttaacccgg
     1861 ataacggaga cggactcttg ggtggcctgc aggacctgga cgagctgtat gactgggaat
     1921 atgagggctt caccaagtgc tctgagtcat gtggaggagg tgtccaggag gctgtggtaa
     1981 gctgcctgaa caaacagacc cgggaactcg ctgatgagaa cctgtgtgtg accagccgac
     2041 ggcccccgca gctcctgaaa tcctgtaact tggatccctg cccagcaagg tgggaaattg
     2101 gcaagtggag cccatgtagc ctcacctgtg gggttggcct gcagaccaga gatgttgtct
     2161 gttcccacct actctccaga gagatgaacg aggtggttgt cctggccgat gagctgtgcc
     2221 atcaccccaa acccagcaca gtgcaagcct gcaaccgttt caattgcccc ccagcctggt
     2281 accctgcaca gtggcagctg tgttccagga cctgtggagg agggattcag aaacgtgatg
     2341 ttctctgcaa gcagcgtatg gctgacggca gcttcctgga gcttccagag accttctgtt
     2401 ctgcctccaa accaacctcc caccaagggt gcaagaaaga tgactgcccc agtgagtggc
     2461 ttctctcaga gtggtcagag tgctctgtga gctgtgggga gggcacccag actcgaagtg
     2521 ccatttgcca gagggtgctg aaaactgggg tctccactgt tgtcaattct actttgtgcc
     2581 ctcccctgcc cttctcttcc tccatcagac cctgtatgct ggcaacctgt gcaaggcctg
     2641 gaaggccttc caccaagcac agtcctcaca tcgcagctgc acgaaacata tacatccaga
     2701 cccgcaggca gaggaagctg cacttcgttg tgggaggatt tgcttacctg cttcccaaga
     2761 ctaccgtggt gctccggtgt cccacacgca gattccgcaa gcccctcatc acgtgggaaa
     2821 aggacggcca gcacagcatc agctcggctc atgtcaccgt agcccctttt ggctacctga
     2881 agatccatcg cctcaagccc tcagatgcgg gcatctacac ctgttctgcg gggcccgccc
     2941 gggagcagtt tgtgattaag ctcattggag gcaaccgcaa gctcgtggcc aggcccctga
     3001 gcctttggag tgaggaagag gaggccctgc aggtgaggaa gaccaatcca aaagaagcct
     3061 tgcaaaccca caaacaccaa aatggcatct tctccaacgg cagcaaagct gagaagcgcg
     3121 gcctcactgc agatcctggg aaccgctatg atgacattgt gtctaggctg ttggagcagg
     3181 gcggctggcc aggagagctc ctggcctcgt gggaggtgca ggactctgca gaaaggaacg
     3241 catcctcaga agaggatccc aatgctgaac aggccctcct gcatctcccc ttcaccatgg
     3301 tggccgagca gaagcgtctg gatgacatcc tcaggaacct gtcccagcag ccagaggagc
     3361 tacgggacct ctacagcaag cacctggtgg cccagctggc ccaggacatc ttccgaagcc
     3421 acctggagaa ccaggatctg cttcctaagc cctctgagca gaggtttcct cccatggccg
     3481 tcccagctca caaacatgtc tctggcttca gcagctccct aaggagctca tctggagagg
     3541 ctggaggtgg ctcccgtagg cctcatcgca agcccgccat cttgcggaag atctcagcgg
     3601 cacagcaact ctcagcctcg gaggtagtca cccacctggg gcagactgtg gctctagcca
     3661 gtgggaccct gagtgtgctt ctgcactgtg aggcggtagg caacccaagg cccaccatcc
     3721 actggaccag gaacggagaa gcagttcaat tcagtgacag gattcttcta cagccagatg
     3781 attccttaca gatcttggca ccagtggaag ctgatgtggg tttctatact tgcaatgcca
     3841 caaatgcctt gggatatgac tctgtctcca ttgctgtcac attagcagga aagccactag
     3901 tgaagacatc ccgaatgact gtgctcaaca cagagaagcc tacagtcaca gtggatatcg
     3961 gtggcaccgt cagaaccgtc cgaggagtga atgtgacaat taactgccaa gtggcaggtg
     4021 tacctgaagc tgaagtcacc tggttcagaa ataaaagcaa attgggctcc tcccaccacc
     4081 tgcatgaggg ctcctcccac cacctgcatg agggctcctt gctgctcaca gatgtgtcct
     4141 tctctgatca aggcctgtat tcctgcaggg cagccaatct acacggagaa cagacagaga
     4201 gcacgcagct cctgattcta gatcccccgc aagtccccac acagttggaa gacatcaggg
     4261 ccttgctctt agccactgga ccgaaccttc cttcggtgct tatgtcccct ctgggaacac
     4321 agctggtcct ggatcctggg aattccgctc tccttggctg ccccatcaaa ggtcacccca
     4381 cccccaatat cacctggttc caaaatggcc agccaattgc cactgccccg gggctgaccc
     4441 accacatctg gggagctgga cagatcctac gagttgcaaa tctcagtgga ggacctcaag
     4501 gggagttcag ctgcctggct cagaatgaag cagggaccct cctgcagaaa gcctctttgg
     4561 tgatccaaga ttactggtgg tctgtggata gactggcaac ctgctccgca tcttgtggta
     4621 atagaggcat tcatcagccg cgactcaggt gtttactgaa caccacggaa gttgaccctg
     4681 agcactgtac aggaaagcct cggcccgccg tgcagcctgt tgcctgcaac cggagagact
     4741 gtccttctcg atggatggtg acgtcctggt ccgcctgtac ccggagttgc ggtggaggtg
     4801 tacaaacccg aagggtgacc tgtcagaagt tgaaagcttc tggtatttct accccggtgt
     4861 ccaatgacat gtgcagtcaa ctggccaaac ggcctgtgga cacccaggcc tgcaaccagc
     4921 agctctgtgt ggaatgggcc ttctccagct ggggccagtg caatgggcct tgcataggcc
     4981 ctcgccttgc tgtgcagcac aggcaggtct tctgccagac ccgggatggc atcaccttac
     5041 catcagagca gtgcagtgcc ctccccaggc ccgtgagcac ccaaaactgc tggtcagagg
     5101 cctgcagtgt acactggaga gtcagcctct ggaccctatg cacggcaacc tgtggcaact
     5161 atggcttcca gtcccggcgg gtggagtgtg ttcacgtgcg caccaacaag gctgtgcccg
     5221 agcacctgtg ttcctggggg ccccggcccg ccaactggca acgctgcaac gtcactccat
     5281 gtgaaaacac tgagtgcaga gacaccacca ggtactgcga gaaggtgaga cagttgaaac
     5341 tctgccagct cggccagttc cgatctcgct gctgtggaac gtgtggcaaa gcatgaagac
     5401 agggcacggg gatgaactct accctggcca cacaaaggac tcacacaacc accttggaca
     5461 tgacttacgc tttcttcctt ttatttattt atttgcccct ccccacacac ccatgtccac
     5521 ctgcacccat gctcccgagg actgtggcat gttttcttat tcagttagct ggaagctagt
     5581 gtggagaaca ggaaaaaaaa aaaaaaagat gtctaaagga gggttgcaga gcagacagca
     5641 gctcccttgc agagctggct cctttctgat cagggtctca gagacacagg aagaccaagc
     5701 catagtctat agggacagca aggagtttat aacacatagg tacaggcaca ggccaatcag
     5761 gagtgccgtt cctttgtttc ctggtggtag gaacaggggg gggggggggg aagcagcata
     5821 ctagagcaga aaccaggcca gactccagtt cttctggcag tggtgtggga agaccaagaa
     5881 agaagagaac tgagctgtgg gcaagagggt tatgccaaaa gagacaagca aaataggcag
     5941 aaggcatgcc gctatgcaga agacagaggc cgggaagaga gaaggaaagc gtgcgcacgc
     6001 acctcagtgg gaggagcttg ctggcaggac agattttcaa gcagtcacgt gagacccata
     6061 tgacaagcct gtgcccggga acatgtgcac agtcctcgag cttcaacaga gttggggaag
     6121 ggtattcaga gtcctctcag ggtacccgcg ctgcgtgaca cgggtgacac tgcatgacat
     6181 gccctttgtg tggttataca agtgtgtcta cccctcttct gtcaagtgac ttttgtgtct
     6241 gcagctgtgg acaacccaac aaagggtcaa ggtcagctgt gcagtaaggc tgcccctagc
     6301 atctccctac ttaagtcaag ggtcactagc catgaactga ctgctgccga gggccaaggg
     6361 catttgatcg tgaatgcccc tggttttcca tccgaatgac tttgctgctc cttgttgggc
     6421 cagggactag aatcatagct cacaaaggat tcattaagca acctgtttgc gggcaagcat
     6481 ctacaggatg tagaaagcct tactaccaga tctcaccaga gaggaggaga ggacggaggg
     6541 gccctgcaca cccacagtgc gctttctctc ccaaccctca cacattgggc ctgggagccc
     6601 ttcctgaacc acagaagagc tgccaattta cgcagcaggc tgggagtagg gagtgtgatc
     6661 aggcgctatg gcaaagctag aagtcagcta aagactcaca agacagccgg agaaagcttt
     6721 gtaaccatcc tctcgactac acagatacta tggtaattag cacaccagac tgagtgaatg
     6781 gaccactcag cgggctaagc agcacacaca attcagcaac acacatcagc tatggcaaaa
     6841 acagaagccc ttggcaaatc ctcagtctgc agagaagctt caacagtaat aatcgcttcc
     6901 ttcctgagca gcctcagttt agcagatgag gcaggcagag cccagtagcc atcagataag
     6961 ccgcccctcg caaacacact caccaaatgc tatcacccca gggccaccac tgacatcagg
     7021 gctgcatttc ccaaccagcc tggaagttaa gtttgaaaga ggatgttaat ctgtgtcttc
     7081 ttagatgcgc tatggacagt tagggtaggc ctcttcctca tcacaaaaat agactctaag
     7141 aaattgtgtt attaaaagtc agtgtaatgt ttatttaaaa ttaaagagag tgtttctatg
     7201 tatatctttt gtgaatattt attaggattt cttgtattaa aaagtgcaat attagtaatt
     7261 gtacattgtc atccagaaaa acaactcttt gggggatttt attaacttcc tgcagctgtg
     7321 ttcctaaaaa ctctgtggca ataattgtat tcttcctaat tttaaatgaa acaaaacaga
     7381 tgtttaactc tgatccactg tgtacagagt accttgtaaa agctaatgtg ggattggggg
     7441 agagcaatgg agtcaatttg tttgtgacac tagttataca taaaatgaac acaaattctg
     7501 taatactaat acatagtaca gtagctatta aaaattggtg gtcagtgttt gaatttttct
     7561 caaatgcagg cgtcttccag ctctgccacc tgccagagtg tgaggttgga agtgcctttc
     7621 agaactagct ggagagcata ggtttggagt ggaaagcagt gtgctccttg catgacatga
     7681 atgtacattt aatatttgtt ctgtgaattg tgactcagca gtaccacaaa ttatcggggc
     7741 tgctggataa tgcggaagaa gacacttcct tctctaaaac acaaaactgt atttatattt
     7801 ttttgtacag ataatacagc ttatttattt
//
