LOCUS       NM_027665               3536 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus a disintegrin and metallopeptidase domain 30 (Adam30),
            mRNA.
ACCESSION   NM_027665 XM_979076
VERSION     NM_027665.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3536)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3536)
  AUTHORS   Grayson,P. and Civetta,A.
  TITLE     Positive selection in the adhesion domain of Mus sperm Adam genes
            through gene duplications and function-driven gene complex
            formations
  JOURNAL   BMC Evol Biol 13, 217 (2013)
   PUBMED   24079728
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3536)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   4  (bases 1 to 3536)
  AUTHORS   Han,C., Choi,E., Park,I., Lee,B., Jin,S., Kim,D.H., Nishimura,H.
            and Cho,C.
  TITLE     Comprehensive analysis of reproductive ADAMs: relationship of ADAM4
            and ADAM6 with an ADAM complex required for fertilization in mice
  JOURNAL   Biol Reprod 80 (5), 1001-1008 (2009)
   PUBMED   19129510
REFERENCE   5  (bases 1 to 3536)
  AUTHORS   Choi,I., Oh,J., Cho,B.N., Ahnn,J., Jung,Y.K., Han Kim,D. and Cho,C.
  TITLE     Characterization and comparative genomic analysis of intronless
            Adams with testicular gene expression
  JOURNAL   Genomics 83 (4), 636-646 (2004)
   PUBMED   15028286
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB615407.1 and AK077058.1.
            
            On Nov 20, 2015 this sequence version replaced NM_027665.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK077058.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                BB615407.1         2-27
            27-3536             AK077058.1         2-3511
FEATURES             Location/Qualifiers
     source          1..3536
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 42.63 cM"
     gene            1..3536
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
                     /note="a disintegrin and metallopeptidase domain 30"
                     /db_xref="GeneID:71078"
                     /db_xref="MGI:MGI:1918328"
     exon            1..3536
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
                     /inference="alignment:Splign:2.1.0"
     CDS             220..2418
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
                     /note="a disintegrin and metalloproteinase domain 30"
                     /codon_start=1
                     /product="disintegrin and metalloproteinase
                     domain-containing protein 30 precursor"
                     /protein_id="NP_081941.1"
                     /db_xref="CCDS:CCDS17660.1"
                     /db_xref="GeneID:71078"
                     /db_xref="MGI:MGI:1918328"
                     /translation="MRSVWAFLPQHRWLFLTMLFHEAVGEEDLLFDPDWGFDSYEITI
                     PKVISFKKGAQGVDSSLSYLLQIEGKARVVHLRPKKLLLPRHLPVFSFTQEGSLIEDY
                     PHIPDQCNYVGSVEGSQESESTLSTCMGGLRGVLNIDSRYYQIEPLRASSSFEHVVYL
                     VTEDNFNNETCGVVDEETGGQTAEEEEMARISSFHQSYKHQRYLELVMVFDLDRFVFA
                     RGNMSRMVDDAILLASIADTYFQDVSLKIQLKALEVWTYYNRIRLYYPSLSEVLGQFV
                     HYKRNSMHHRLPADWFHLYIARRYIDANAWSWGRACEEFHAGSASSFLNVNILGPATW
                     TAHELGHCVGMIHDEEFCQCRGRKSCIMGTGRTGFSNCSYHQYFLHASYKMSYCLSDF
                     PKLHIVERCGNKIVENKEECDCGSKEDCKKDLCCGPDCKWKEGVNCSSGLCCHKCNFL
                     PSGYVCRKEVNECDLEEYCDGTSGVCPDDSYKQDGTPCRNGGFCFRKGCRSRYLQCQS
                     IFGRKAKEAPHQCYEAVNMLGDQSGNCGIVNATRYTRCHRGNTICGRLQCINVKALSK
                     FPDHTIILSTYLRGDNLICWGTSYHGTMIPHGVPDIGDISDGTSCGRNRVCLNRTCVD
                     YTNLKFDCLPDKCNSRGVCNNRKNCHCSYGWEPPFCVEVGYGGSLDSGPPGPRIEVLS
                     TTSALYMLRTILFLVSMIVVCLGQLIRNLFRNRRRNLQQKNPAETQGKKR"
     regulatory      2475..2480
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
                     /note="hexamer: AATACA"
     regulatory      2483..2488
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
                     /note="hexamer: AATGAA"
     polyA_site      2492
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
                     /note="major polyA site"
     polyA_site      2502
                     /gene="Adam30"
                     /gene_synonym="4933424D07Rik; svph4"
ORIGIN      
        1 ggaactggat gcgttaggta aggggcgcgc ctggggaaac ccgccatcta ggccctgaga
       61 gtcccgtttt cccaggaaag cctgccagag gagcagtgcg cctggggctc ctgcgcttat
      121 agaggagtcc catggaaatc tgatgcacaa accaggctgg agttgctcct gctactcctg
      181 ggtccaggac aaaccaagcg gggataaata gaacagatca tgaggtcagt gtgggccttc
      241 ctgccccagc accgctggct gtttctgacg atgctctttc atgaggctgt aggcgaagaa
      301 gacctactat ttgaccctga ctggggcttt gactcatatg aaatcaccat tcccaaagta
      361 ataagcttta agaaaggggc gcagggtgta gacagttctt tgtcatacct cttacagata
      421 gaaggcaagg cgcgtgttgt tcacctgcga cccaagaagt tactgttgcc aagacatctg
      481 ccagttttct ccttcactca agagggcagt ctgatagagg attatccgca tataccagac
      541 cagtgtaatt acgtgggctc cgtggaaggc tctcaggaat ccgaatctac tctgagtaca
      601 tgcatgggag gtctgcgagg cgtactgaac attgactcca gatactacca aatcgagccc
      661 ctcagggcct cttccagttt cgaacacgtg gtgtatctcg taactgagga caactttaac
      721 aatgagactt gtggtgtggt tgatgaagaa acaggtgggc aaacagccga ggaagaggag
      781 atggctagga taagtagttt tcatcagtcc tacaagcacc aaaggtacct ggaactggtc
      841 atggtctttg acctggatag attcgtgttt gcccgtggca atatgtctag gatggtggat
      901 gacgccattc ttttggcttc aattgcagac acctactttc aggatgtcag cttgaagatt
      961 caactgaaag cgcttgaagt ctggacatac tataatagaa tacgtcttta ttatcccagt
     1021 ttatctgaag ttttaggtca attcgtgcat tacaaaagaa actcaatgca tcaccggctt
     1081 cccgcggact ggttccattt atatattgcg agaagatata tagatgctaa tgcatggtcc
     1141 tggggaagag cctgtgaaga attccatgct ggatcagcaa gcagcttcct caatgttaat
     1201 atccttgggc ctgctacttg gactgctcat gaattgggcc attgtgtggg gatgatacat
     1261 gatgaggaat tctgtcagtg tagaggtagg aagagctgca tcatggggac aggacgtaca
     1321 gggtttagta actgtagtta ccatcagtat tttttacacg catcttataa aatgtcctat
     1381 tgtctgtctg acttcccaaa gctacatatc gtagagaggt gtggaaataa aattgtggaa
     1441 aacaaagagg aatgtgactg tggttctaaa gaagactgca aaaaagacct gtgctgtggg
     1501 ccggactgta aatggaaaga aggtgtcaac tgctcctctg ggctttgctg tcataaatgt
     1561 aacttccttc catcaggata tgtgtgtagg aaggaagtga atgagtgtga cctcgaagag
     1621 tactgtgatg ggacctcagg tgtctgtcca gatgactctt acaagcagga tggaactcca
     1681 tgcagaaacg gaggcttttg tttccgtaag ggatgcagat ccaggtacct gcagtgccag
     1741 tctatctttg ggcgtaaagc caaggaggcc cctcaccagt gttacgaagc agtgaacatg
     1801 ttaggtgacc agtctgggaa ctgtggcatt gtaaatgcta cccgatatac aaggtgtcat
     1861 agaggcaaca caatctgtgg caggctacag tgtatcaatg ttaaagccct ctccaaattt
     1921 ccagatcaca ccattatact gtccacttat ctgaggggag ataatctcat ttgctggggc
     1981 acaagctatc atggaaccat gataccccat ggggtacctg acataggtga cattagtgat
     2041 ggtacctcct gtggtcgtaa tcgggtgtgt cttaacagga cttgtgtgga ctacaccaac
     2101 ctgaagtttg actgtttacc tgacaagtgc aatagccgag gtgtttgcaa caatagaaag
     2161 aattgccatt gctcatatgg ctgggaaccc ccattttgtg tagaggtagg atacggtggg
     2221 agccttgaca gtgggcctcc tggacccagg atagaagtac tttcaacgac tagtgctctg
     2281 tacatgttgc gtactatctt attcctcgtc tccatgattg ttgtgtgttt ggggcagctg
     2341 ataagaaatt tgtttcgtaa tcgccgccgt aatctccagc aaaaaaatcc agctgagacg
     2401 caggggaaga agaggtgaga gggagcgact ggtaggcgag gagggagagg gaattgtgat
     2461 caggatgtaa agtaaataca ctaatgaatg aatgaaaaat aatccctttg ttttgtattc
     2521 acacaggggt gactttggca cttggagtgg catttttgta ttcatggctc atgttaaagt
     2581 cctactatct gcaatacatt gtagtgggac tttctggatc ctccagttaa atgatgacac
     2641 cgagacttat taatttgttt gatagcttag gcctttagct gggcagactc tgagctattg
     2701 actatcctag cccacgacct gccacatgcc tagttacctc tctgcgtctg ctcacatctg
     2761 gccaccgctt tgtcccgctg gtgaatccct gcttctaatg gttttctccc agagacccta
     2821 tctcagttca gaagctctgc cttccccttt ctgcctagct gttgtccacc agttctttat
     2881 taagccaatg gacaagcgag ggaggtgact gtttatgcag tataaggcag gtgagaagcc
     2941 ataagaataa cagttctcag ctctctgctg gtacagcagt caatggttgg atatacagag
     3001 acaaccttca cacagtgcat cccaacaatc tatagatctt gcttgggatc cttatttaag
     3061 tatttgatca atgctatata gctgggtcac aacaataatt tgagattccc ctgcttatca
     3121 ctgatgcaat tcctaggctt ctttctcaaa gacaaaaact ataaaaactc cccaggagca
     3181 gagtgtaaca gagtgtggtt aaatctgtac cgtaaatttc ttcctaatat tagtgtaatt
     3241 tacttacatt atttttactt aagccaccca taagggcatt aaaatataaa acatgattca
     3301 aatgttaaaa aaaaaagcaa aaccaaaaat aaaacaaaac aaaaatagcc aagactctat
     3361 ctaaagcaaa gaaggtcagg tcataaatgt gaccagcaat cctgtcatct aatatatttg
     3421 gtcatttaac aagttcacca tttattcaaa tgactcttca ttattttccc agaatgatat
     3481 cgtgcaaatt tcccatacat ttcaaatcag caaaaataaa ctatattatt gtttgg
//
