LOCUS       NM_007400               7675 bp    mRNA    linear   ROD 30-OCT-2023
DEFINITION  Mus musculus ADAM metallopeptidase domain 12 (Adam12), mRNA.
ACCESSION   NM_007400
VERSION     NM_007400.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7675)
  AUTHORS   Piotrowski KB, Blasco LP, Samsoe-Petersen J, Eefsen RL, Illemann M,
            Oria VO, Campos KIA, Lopresti AM, Albrechtsen R, Sorensen CS, Sun
            XF, Kveiborg M and Gnosa S.
  TITLE     ADAM12 expression is upregulated in cancer cells upon radiation and
            constitutes a prognostic factor in rectal cancer patients following
            radiotherapy
  JOURNAL   Cancer Gene Ther 30 (10), 1369-1381 (2023)
   PUBMED   37495855
  REMARK    GeneRIF: ADAM12 expression is upregulated in cancer cells upon
            radiation and constitutes a prognostic factor in rectal cancer
            patients following radiotherapy.
REFERENCE   2  (bases 1 to 7675)
  AUTHORS   Oh HH, Park YL, Park SY and Joo YE.
  TITLE     A disintegrin and metalloprotease 12 contributes to colorectal
            cancer metastasis by regulating epithelial-mesenchymal transition
  JOURNAL   Int J Oncol 62 (4) (2023)
   PUBMED   36866761
  REMARK    GeneRIF: A disintegrin and metalloprotease 12 contributes to
            colorectal cancer metastasis by regulating epithelialmesenchymal
            transition.
REFERENCE   3  (bases 1 to 7675)
  AUTHORS   Wang G, Romero Y, Thevarajan I and Zolkiewska A.
  TITLE     ADAM12 abrogation alters immune cell infiltration and improves
            response to checkpoint blockade therapy in the T11 murine model of
            triple-negative breast cancer
  JOURNAL   Oncoimmunology 12 (1), 2158006 (2022)
   PUBMED   36545255
  REMARK    GeneRIF: ADAM12 abrogation alters immune cell infiltration and
            improves response to checkpoint blockade therapy in the T11 murine
            model of triple-negative breast cancer.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7675)
  AUTHORS   Lamin V, Verry J, Dokun OS, Kronemberger A, Wong T, Lira VA and
            Dokun AO.
  TITLE     microRNA-29a Regulates ADAM12 Through Direct Interaction With
            ADAM12 mRNA and Modulates Postischemic Perfusion Recovery
  JOURNAL   J Am Heart Assoc 11 (16), e025727 (2022)
   PUBMED   35946473
  REMARK    GeneRIF: microRNA-29a Regulates ADAM12 Through Direct Interaction
            With ADAM12 mRNA and Modulates Postischemic Perfusion Recovery.
REFERENCE   5  (bases 1 to 7675)
  AUTHORS   Zhu YN, Gan XW, Pan F, Ni XT, Myatt L, Wang WS and Sun K.
  TITLE     Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression:
            implications for fetoplacental growth
  JOURNAL   BMC Med 20 (1), 189 (2022)
   PUBMED   35610640
  REMARK    GeneRIF: Role of EZH2-mediated H3K27me3 in placental ADAM12-S
            expression: implications for fetoplacental growth.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7675)
  AUTHORS   Galliano MF, Huet C, Frygelius J, Polgren A, Wewer UM and Engvall
            E.
  TITLE     Binding of ADAM12, a marker of skeletal muscle regeneration, to the
            muscle-specific actin-binding protein, alpha -actinin-2, is
            required for myoblast fusion
  JOURNAL   J Biol Chem 275 (18), 13933-13939 (2000)
   PUBMED   10788519
REFERENCE   7  (bases 1 to 7675)
  AUTHORS   Nelson KK, Schlondorff J and Blobel CP.
  TITLE     Evidence for an interaction of the metalloprotease-disintegrin
            tumour necrosis factor alpha convertase (TACE) with mitotic arrest
            deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9
            with a novel MAD2-related protein, MAD2beta
  JOURNAL   Biochem J 343 Pt 3 (Pt 3), 673-680 (1999)
   PUBMED   10527948
REFERENCE   8  (bases 1 to 7675)
  AUTHORS   Kurisaki T, Masuda A, Osumi N, Nabeshima Y and Fujisawa-Sehara A.
  TITLE     Spatially- and temporally-restricted expression of meltrin alpha
            (ADAM12) and beta (ADAM19) in mouse embryo
  JOURNAL   Mech Dev 73 (2), 211-215 (1998)
   PUBMED   9622634
REFERENCE   9  (bases 1 to 7675)
  AUTHORS   Inoue D, Reid M, Lum L, Kratzschmar J, Weskamp G, Myung YM, Baron R
            and Blobel CP.
  TITLE     Cloning and initial characterization of mouse meltrin beta and
            analysis of the expression of four metalloprotease-disintegrins in
            bone cells
  JOURNAL   J Biol Chem 273 (7), 4180-4187 (1998)
   PUBMED   9461614
REFERENCE   10 (bases 1 to 7675)
  AUTHORS   Yagami-Hiromasa T, Sato T, Kurisaki T, Kamijo K, Nabeshima Y and
            Fujisawa-Sehara A.
  TITLE     A metalloprotease-disintegrin participating in myoblast fusion
  JOURNAL   Nature 377 (6550), 652-656 (1995)
   PUBMED   7566181
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC126676.3, AC140055.4 and
            AC125372.4.
            
            [WARNING] On Jan 18, 2024 this sequence was replaced by
            NM_007400.3.
            
            On Nov 8, 2006 this sequence version replaced NM_007400.1.
            
            Summary: This gene encodes a member of a disintegrin and
            metalloprotease (ADAM) family of endoproteases that play important
            roles in various biological processes including cell signaling,
            adhesion and migration. The encoded preproprotein undergoes
            proteolytic processing to generate a mature, functional protein
            that localizes to the cell surface. About a third of the mice
            lacking the encoded protein die before weaning. Overexpression of
            the encoded protein in a mouse model of Duchenne muscular dystrophy
            alleviates the muscle pathology by preventing cell necrosis and
            inflammation. [provided by RefSeq, May 2016].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D50411.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-311               AC126676.3         70922-71232
            312-409             AC126676.3         123139-123236
            410-483             AC126676.3         161227-161300
            484-562             AC140055.4         86535-86613         c
            563-639             AC140055.4         72416-72492         c
            640-826             AC140055.4         55662-55848         c
            827-892             AC140055.4         49721-49786         c
            893-964             AC140055.4         48594-48665         c
            965-1134            AC140055.4         42089-42258         c
            1135-1219           AC140055.4         38979-39063         c
            1220-1368           AC140055.4         35342-35490         c
            1369-1546           AC125372.4         121950-122127       c
            1547-1636           AC125372.4         116260-116349       c
            1637-1832           AC125372.4         114421-114616       c
            1833-1941           AC125372.4         104335-104443       c
            1942-2140           AC125372.4         104032-104230       c
            2141-2218           AC125372.4         100940-101017       c
            2219-2327           AC125372.4         97344-97452         c
            2328-2463           AC125372.4         94355-94490         c
            2464-2572           AC125372.4         93622-93730         c
            2573-2746           AC125372.4         92032-92205         c
            2747-2877           AC125372.4         74702-74832         c
            2878-7675           AC125372.4         67727-72524         c
FEATURES             Location/Qualifiers
     source          1..7675
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 77.61 cM"
     gene            1..7675
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /note="ADAM metallopeptidase domain 12"
                     /db_xref="GeneID:11489"
                     /db_xref="MGI:MGI:105378"
     exon            1..311
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            312..409
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            410..483
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            484..562
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            563..639
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            640..826
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            827..892
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            893..964
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1134
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1219
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1368
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1546
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..1636
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1832
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..1941
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            1942..2140
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2141..2218
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2327
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2328..2463
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2464..2572
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2746
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2877
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
     exon            2878..7675
                     /gene="Adam12"
                     /gene_synonym="Mltna"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccagagtag cgcgcgcgcg cacgcacaca cacggggagg ggagaaagtt tttttttgaa
       61 aaaatgaaag gctagactcg ctgctcagcg acccgggcgc tgcgcgaggg ggtcgcggca
      121 gactcagggc agtaggactt cccccagctc ggcgcccgcg tgggatgctg cagcgctggc
      181 cgcggggccc ccgaagcagc tgcacgccag gccggcgaca atggcagagc gcccggcgcg
      241 gcgcgcgccc cccgcccgcg ccctcctgct ggccctggct ggggccctgc tggcgccccg
      301 tgcagcccga gggatgagtt tgtgggacca gagaggaact tacgaagtgg ccagagcctc
      361 ccttctgagc aaggaccctg ggatcccagg acagagcatc ccagccaagg atcatccaga
      421 cgtgctgact gtgcaactgc agctggagag ccgagacctg atcctcagcc tggaaaggaa
      481 tgagggactc attgccaatg gcttcacgga gacccattat ctgcaagatg gtactgatgt
      541 ctctctcact cgaaatcaca cggatcattg ttactaccat ggacatgtgc aaggagatgc
      601 tgcatcagtg gtcagcctca gtacttgctc tggtctccgg ggacttatca tgtttgaaaa
      661 taaaacgtac agcttagagc caatgaaaaa caccactgac agctacaaac tcgtcccagc
      721 tgagagcatg acgaacatcc aagggctgtg tgggtcacag cataacaagt ccaacctcac
      781 catggaagat gtctcccctg gaacctctca aatgcgggca agaaggcata agagagagac
      841 ccttaagatg accaagtacg tagagctggt tattgtggca gacaacagag agtttcagag
      901 gcaaggaaaa gacctggaga aagttaagca gcgattaata gagatcgcca atcacgttga
      961 caagttttac agaccactga acatccggat cgtgctggta ggagtggaag tgtggaatga
     1021 catcgacaaa tgctctataa gccaggaccc attcaccagc ctccatgagt ttctagactg
     1081 gagaaagata aagcttctac ctcgaaaatc ccacgacaat gctcagctta tcagtggggt
     1141 ttatttccaa ggaaccacca tcggcatggc acccatcatg agcatgtgca ctgcagaaca
     1201 gtctggagga gttgtcatgg accattcaga cagccccctt ggtgccgcag tgaccttggc
     1261 acatgagctg ggccacaact tcgggatgaa ccatgacaca ctggagaggg gctgcagctg
     1321 cagaatggcc gcagagaaag gaggctgcat catgaacccg tccacggggt tcccattccc
     1381 catggtgttc agcagctgca gcaggaagga cctggaggct agcctggaga agggcatggg
     1441 gatgtgcctc ttcaacctac cagaggtcaa gcaggccttt gggggccgga agtgtggaaa
     1501 tggctatgtg gaagagggag aagagtgtga ctgcggagaa ccggaggaat gcacgaatcg
     1561 ctgctgtaac gctaccacct gtactctgaa gccagatgct gtgtgcgcgc acgggcagtg
     1621 ctgtgaagac tgtcagctga agcctccagg aactgcatgc aggggctcca gcaactcctg
     1681 tgacctccca gaattctgca cagggactgc ccctcactgt ccagccaatg tgtacctaca
     1741 tgatggccac ccgtgtcagg gcgtggatgg ttactgctac aacggcatct gccagaccca
     1801 tgagcagcag tgtgtcacgc tctggggacc aggtgctaaa ccggctcctg gcatctgctt
     1861 tgagcgagtc aactctgcag gagatcctta tggtaactgt ggcaaagact ccaagagcgc
     1921 cttcgccaaa tgtgagctga gagatgccaa gtgtgggaaa atccagtgtc aaggtggtgc
     1981 aagccgacct gtcattggta ccaatgctgt ttccatagaa acaaatatcc cacagcagga
     2041 aggaggtcgg attctgtgcc gggggaccca tgtgtacttg ggtgatgaca tgccagaccc
     2101 agggcttgtg cttgcaggaa caaagtgtgc agaaggaaaa atctgcctca atcgtcgatg
     2161 tcagaatatc agtgtcttcg gcgttcacaa gtgtgccatg cagtgccacg gccgaggggt
     2221 atgtaacaac aggaagaatt gccactgtga agcccactgg gctccaccct tctgtgacaa
     2281 gtttggcttt ggaggaagca cagacagtgg tcccatcagg caagcagata accagggctt
     2341 gactgtagga atcctggtga gcatcctgtg tctgcttgct gctggatttg tggtgtatct
     2401 caaaaggaag acgttgatgc ggctgctgtt cacacataaa aaaaccacca tggaaaagct
     2461 aaggtgtgtg cacccttccc ggacacccag tggccctcac cttggccagg ctcaccacac
     2521 ccccgggaaa ggcctgctga tgaaccgggc accacatttc aataccccca aggacaggca
     2581 ctcgctgaaa tgccagaaca tggacatcag caggcccctc gacgctcgag ccgtcccaca
     2641 gcttcagtca cctcagcgag tgctcctgcc tctccaccag accccacgtg cacccagtgg
     2701 ccctgccagg cccctgcccg ccagtcctgc agtcaggcag gcccagggca ttcgaaaacc
     2761 cagtcctcct cagaagcctc tgcctgctga tccactgagc aggacttctc ggctcactag
     2821 tgccttggtg aggaccccag ggcagcagga acctgggcac cgcccagccc ccatcagacc
     2881 tgcccctaag catcaagtac ccagaccttc ccacaatgcc tatatcaagt gagaagccag
     2941 cccagaccgg tcctcaacag tgaagacaga agtttgcact atcttcagct ccattggagt
     3001 tgttgttgta ccaactttcc gagtttctaa agtgtttaaa acaccattct ctccagaccc
     3061 tggagccact gccatcggtg ctgtgctgtg gtgctttgtg tacttgctca ggaacttgta
     3121 agttattaat ttatgcagag tgtctattac tgcgcagggc gccgtagcag gcatttgtac
     3181 catcacaggg cttttctaca gaaggaaggc tcctcgtgct tttgtttttc tggaggactt
     3241 gaaataccct gcttgatggg acctaagatg agatgtttac tttctattca aggccttatc
     3301 ggaaaatagc tccccacctt cccaaggctg ttatggtacc agacacacag ctcaggacac
     3361 cccagggaga acctggcatg ggttttcttt gtttgctttc attttatctt ttatattttg
     3421 gtatccctat cttgggttgt agccagggcc ttcaggaagg tcttgggcca ctgcatgcta
     3481 atggccttca ggtcctgcac cctgaagctc tcagacaaca agtaggatct gctttctagc
     3541 cagcagcttt ggagagaacc tggggtactg aaaagaaggt ttggggtgtg gttataccag
     3601 gatggagact ggaatcctaa tctgggcaaa catctgacct tgagctgagc agccatgagc
     3661 acctctagga agcaaggacg gctgaggtgc tgcacaaggc tctgctttga gagctggcag
     3721 gggcttctct ctggctgccc tttgcagagt gctagctggc atggcatgtt gtttacatcg
     3781 ggaacagtgg tgtttctaca agaaagccac tgcctgggca ctgcagacct ccgtctcctg
     3841 cccatttaga gctaagcaaa ttaccacatt gtcttctgga ctgtaataca atgaccctgt
     3901 gttctgacag atagaggagg ctttctatgg aaccataact attttcagat gtgaactagt
     3961 aaccagatct agtcgatcaa ctctggagat agaaatctcc tttttactgc aaggctcgac
     4021 ttattaaaaa ttaggcagaa tccatatgct tgcaaaagct ataaccacgt ggaatgctct
     4081 tctcatggca cagcctgagt ctggtatcct tattagtagc cattggacaa agcacccaaa
     4141 gttacctgtg tgttctcttc aaggcatcct aatttcttca gcatagagag actcggtctt
     4201 cctcacattc tgaacatacc tatcaatgac taagacagca aggcaatccg tttccgaata
     4261 ctgagttgct cacgaaaggc aacctcagcc aggcaactct ttccctctgc tctttcagta
     4321 tgtgactggg aagctacctt cagaagcaaa tcttcaaggt gcctcaaccc aatggcatga
     4381 aagatatata tttaaaaaat aataatgtaa tgccagaggc cttccctgcc tccagatggg
     4441 gcgtaggatg actagctttc acgacagaag gtaaatgaca gcagtcctct acctcgtctg
     4501 actgctttaa gatcaaggct tctttggaag ggtaactaac attaatggct ggcctgtgcc
     4561 ttgaagcaga agggaaaata cagataagga atttggtttg ctttctagaa tccaaaactg
     4621 tatccagcat tgggaagcat ggtcttcatg actgggtaaa taaatccacg tcacagatgc
     4681 ataaaagaat aactcttatg acatgcctct ttttgtggca cagagacaat attgctgcca
     4741 ctgagatgca tacaaaattt ctgtaactga tatgtcattc agtagttgta ttaaggccaa
     4801 acatccacaa ctgtaaagac ttatagagtt gtgtgggcgt tgtcttgtga gacacacaaa
     4861 gcctcagctg aagcgtatga gctcctcctc caggtgggag tgatggggag gctagaaaca
     4921 cacaaagaca acagaagagc tttggtttgg ggggggtgca gagagagtgt ggtttagagg
     4981 aagttggagc catgatcttc tgccatctcc ccagtgtcca ctaaggatgc cgatggtgcc
     5041 ttaccagctg tgcagtgctg gctgcttgct tttacagagc catgcattca tttctgaata
     5101 agaacatatt taatcctgaa attcccttac aggacagaca gtgttactaa aggaattcct
     5161 ctaagataca gtagttgtca attaaagcat atttagcagt aacttcaatt ttaacaaaat
     5221 tgggacccaa tagccagcat gagggttctt tgacagaggg tagtttctct ctccctttct
     5281 ccatccttca aatgacaaga cgtcaaaact aatacagttc atttgcagtc catctcatgc
     5341 ttatacatac tagaggtatg actaaagttg gttgagtcat gggagaccat ccctgagaaa
     5401 gtccagtcgg tcaagagcct tgccaggtgg cgtggctgga cgtcctcctt ttgttcctgc
     5461 actgaggaat agttataggt tatgtgaccc cacttcacag gcaagtggga ggcgaacctt
     5521 gcaggcatgc cccttaaaag ctggtctcag acctacaata gtcctgagtc tgttttccca
     5581 gcacacagag agcaacaatg cagttttcca tttcaaaata tgcatgccga gtttgcgctc
     5641 tgtgtgagtg tttccaggtt acacatatgg gatgacatca cagaaaccac acaagcaaca
     5701 aattaaattc tacgggaaga aatcctcctg actggtctct gaggagacat ttttatgcct
     5761 tcttaacttt attaggaact ctcaggctga agctatgggt cattgttctc caacaaatca
     5821 atacaagcca tcaatgcact ctcgaagaac tgccaaaccc tgatctgtgt gaatgttctc
     5881 aggagcctgt gatccccatg gtgctacaaa gaggctggag ctgggccaac aagaaggcct
     5941 aagagtcctc ctgcctctca gcagatgttt actgagcact ctgagccaga agcaccccga
     6001 caaccaggag gacgatggct gggcagtagg gcgcccagcc acttgcagct ctttcctctg
     6061 aggcccgctt tgtgttttaa ttcccttctg tcaggcccca gccagaggac actgtctata
     6121 gatcctccct ctcagttttc agacggccta agccatacac aaatgaccca gactaagaaa
     6181 caccaatact cccagcagtc ccaagaactg gtttttaaac actatgacaa gtagaagagg
     6241 gtgtcacaga ggccattttt tttcttttct ttccactcat actggaacct aggtcctctc
     6301 tctacactcc tagttccttt acacaactcg gcagtggctc cattacacca aggacacaga
     6361 aaaacacagg taccgatttg ccttcctctc ctgccaatca caagtgcctt actctgacca
     6421 gacccatgac aaaacctctg tcatccaaga gagccaactc tctacctttg ttactacttc
     6481 aagccaatgt ggtaactgct aaccttcaag ggtcacctaa acagtatagt ccaaccttca
     6541 ccaggaccat agcacagagc aacctccagc acacacacac acacacacct tgaatctatc
     6601 ccacagcata tcaaccacag tgacctccct cccaccgcct tgttctaatt acaaggtgaa
     6661 gatggccata gaaaatcaag ttagcactaa ttacaaaatg cttttgatgc aacctgaatt
     6721 tcccaatggc acctattgct ttgaaactct gatgagttaa gtcatgctct gggagctgtg
     6781 agccccatgc tcagatccac tgggcagggg ggactccttg caggagacat gggcacacat
     6841 atgaatgtac catttccatg ccttttgtgg agtacagaca tataaacata aatacttcca
     6901 ttcacgcaca cacgcttaca ttaggagtag tagtaagttt attatcaaaa cactgcaagc
     6961 ttttctccta taagagaaac taggaaggga aaatgttgag tgtggaattc ttaggatgct
     7021 cagtatggac agagatcacc aggaggccct aacactcagg aatcattttc aacctgggaa
     7081 acgatttggc ccctgcaagt tgaaagcccc accacctgcc tacctttcta tatcatacat
     7141 catgttctgc gtgatctgaa attctccaag aaagtaacat tttagccctt aatttagcac
     7201 attgaaattg agatagagcc gatgtcacgt ggctttcctt ataatccgat cagacgctgg
     7261 tttatgctca ctggcctgtg tgctgctatg tcagaaggca gtgatcagaa agcacacaaa
     7321 tctcatgaga ctagaaacac aattaacagc cctcccgtca gggcaacttg gtagtggttg
     7381 ggatagccag tcatctgaat atttgtggca accaacagca caacccgagc tggccacaga
     7441 ctgcttagct ctgttctgac tgatagtaca tctcagttaa ccggcacagc ctttctgcag
     7501 ggcttcgtct acggagagcg ctttggttag cttgttttca tgtttgtatg ttacatgctg
     7561 ttatttttgt acgcatttct catatggggg aatctacagg taaacacagc ctccgagttc
     7621 agtagaaaat gtcattgtta agagtattat atccaataaa cagtaaacag ataaa
//
