LOCUS       NM_025421                648 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus acylphosphatase 1 (Acyp1), transcript variant 3, mRNA.
ACCESSION   NM_025421
VERSION     NM_025421.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK004176.1 and BC096417.1.
            
            On Jun 15, 2018 this sequence version replaced NM_025421.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004176.1, BY704420.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-640               AK004176.1         1-640
            641-648             BC096417.1         614-621
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.62 cM"
     gene            1..648
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /note="acylphosphatase 1"
                     /db_xref="GeneID:66204"
                     /db_xref="MGI:MGI:1913454"
     exon            1..126
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            127..218
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..434
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /EC_number="3.6.1.7"
                     /note="isoform 3 is encoded by transcript variant 3;
                     acylphosphate phosphohydrolase 1; acylphosphatase,
                     organ-common type isozyme; acylphosphatase 1, erythrocyte
                     (common) type"
                     /codon_start=1
                     /product="acylphosphatase-1 isoform 3"
                     /protein_id="NP_079697.1"
                     /db_xref="CCDS:CCDS26055.1"
                     /db_xref="GeneID:66204"
                     /db_xref="MGI:MGI:1913454"
                     /translation="MAEGDTLVSVDYEIFGKVQGVFFRKYTQAEGKKLGLVGWVQNTD
                     RGTVQGQLQGPVSKVRFMQQWLETRGSPKSHIDRANFNNEKVIANLDYSDFQIVK"
     exon            219..648
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      620..625
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      642
                     /gene="Acyp1"
                     /gene_synonym="1110039O14Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctctaaact tccggaagtg gcggttaaca cggctcgggc ggttgatctg aaggtcttcg
       61 gggctgttca gcggctcctg gggaagcccc agaaactcga gcttccgccg ctcggatcat
      121 ccaagtgttt gagcatggca gaaggggaca ccttggtctc agtggattac gaaatttttg
      181 gaaaggttca aggggtgttt ttccgcaagt acactcaggc tgagggtaaa aagctaggtt
      241 tggtgggctg ggttcagaac accgaccggg gcaccgtgca agggcaactg cagggccccg
      301 tctccaaggt gcgcttcatg cagcagtggc tggagaccag aggaagtccc aagtcgcaca
      361 ttgacagagc aaacttcaac aatgagaaag tcatcgcaaa cttggattat tcagacttcc
      421 aaattgtaaa ataatgaaac gaatcttaat attttttcaa aataatctca ctcctttttt
      481 taaatcgcta gattaaaaaa aaaatagaac tattctgtgc tcagtattag aatttgttag
      541 taagttattt tggttgcatg ttggaaaagt taccacgtat tacaagtatg atgaaataca
      601 aatgtgtata attctaacca ataaaaacac attagaacct tatgctta
//
