LOCUS       NM_027493               2121 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus ARP8 actin-related protein 8 (Actr8), mRNA.
ACCESSION   NM_027493
VERSION     NM_027493.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2121)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2121)
  AUTHORS   Nishihara,H., Kobayashi,N., Kimura-Yoshida,C., Yan,K., Bormuth,O.,
            Ding,Q., Nakanishi,A., Sasaki,T., Hirakawa,M., Sumiyama,K.,
            Furuta,Y., Tarabykin,V., Matsuo,I. and Okada,N.
  TITLE     Coordinately Co-opted Multiple Transposable Elements Constitute an
            Enhancer for wnt5a Expression in the Mammalian Secondary Palate
  JOURNAL   PLoS Genet 12 (10), e1006380 (2016)
   PUBMED   27741242
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2121)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 2121)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 2121)
  AUTHORS   Min,J.N., Tian,Y., Xiao,Y., Wu,L., Li,L. and Chang,S.
  TITLE     The mINO80 chromatin remodeling complex is required for efficient
            telomere replication and maintenance of genome stability
  JOURNAL   Cell Res 23 (12), 1396-1413 (2013)
   PUBMED   23979016
REFERENCE   6  (bases 1 to 2121)
  AUTHORS   Tian,E., Sawyer,J.R., Largaespada,D.A., Jenkins,N.A., Copeland,N.G.
            and Shaughnessy,J.D. Jr.
  TITLE     Evi27 encodes a novel membrane protein with homology to the IL17
            receptor
  JOURNAL   Oncogene 19 (17), 2098-2109 (2000)
   PUBMED   10815801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT009536.7.
            
            On May 17, 2008 this sequence version replaced NM_027493.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027281.1, AK017815.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-252               CT009536.7         57755-58006
            253-423             CT009536.7         62017-62187
            424-534             CT009536.7         63448-63558
            535-639             CT009536.7         65344-65448
            640-813             CT009536.7         65695-65868
            814-907             CT009536.7         66340-66433
            908-1040            CT009536.7         66637-66769
            1041-1194           CT009536.7         67607-67760
            1195-1290           CT009536.7         68371-68466
            1291-1431           CT009536.7         69078-69218
            1432-1696           CT009536.7         70122-70386
            1697-1860           CT009536.7         71010-71173
            1861-2121           CT009536.7         72379-72639
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 18.37 cM"
     gene            1..2121
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /note="ARP8 actin-related protein 8"
                     /db_xref="GeneID:56249"
                     /db_xref="MGI:MGI:1860775"
     exon            1..252
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..2004
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /note="actin-related protein 8 homolog; ARP8 actin-related
                     protein 8 homolog"
                     /codon_start=1
                     /product="actin-related protein 8"
                     /protein_id="NP_081769.2"
                     /db_xref="CCDS:CCDS26891.1"
                     /db_xref="GeneID:56249"
                     /db_xref="MGI:MGI:1860775"
                     /translation="MTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQ
                     SNFIVVIHPGSTTLRLGRATDTLPVSVPHVIARRHKQQGQPLYKDNWLLREGLNKPES
                     NEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTS
                     QQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQK
                     YLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGL
                     SSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQL
                     TNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMAL
                     FYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIG
                     FEGDLRGQSSDLPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKA
                     LGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRI
                     IENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW
                     "
     exon            253..423
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            424..534
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            535..639
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            640..813
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            814..907
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1040
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1194
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1290
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1431
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1696
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1860
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..2121
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2027..2032
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /note="hexamer: CATAAA"
     polyA_site      2046
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /note="major polyA site"
     regulatory      2090..2095
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /note="hexamer: ATTAAA"
     polyA_site      2119
                     /gene="Actr8"
                     /gene_synonym="5730542K05Rik; ARP8"
                     /note="major polyA site"
ORIGIN      
        1 gacgccggtg gcggccattt tgactgtggg cagccagggg acgccgcgcc tgcgcaatgg
       61 ttctcctctg actgctgtgg cgtcggtgtc ccagagcccc ggggctggtg gtggtccacg
      121 gtggcagaga tgacccaagc cgagaagggg gacgcggaga acgggaagga gaagggcggg
      181 gagaaggaga aggagcagcg cggcgtgaag cggcccatcg tacccgcgtt ggtccccgag
      241 tcgctgcagg agcaaatcca gagcaacttc attgttgtca tacacccagg ttcaacaact
      301 ctaagacttg gccgagccac agatacactt ccggtcagtg ttcctcacgt cattgcacga
      361 agacacaaac aacaagggca gcccctgtac aaggacaact ggctcctaag ggaaggacta
      421 aataaacctg aaagtaatga acaaagacaa aatggcctta aaatggtgga ccaggcaata
      481 tggtctaaaa agatgtcaaa cggtacaagg cggatccctg tgtcaccaga acagacacgc
      541 tcctacaaca agcagatgcg acctgccatt ctagatcact gttctggaaa caaatggaca
      601 aacacatctc agcagcctga gtatttggta ggagaagagg ccttgtatgt taaccccctg
      661 gactgttaca acattcactg gcctatcaga aggggtcagc tgaacatcca cccaggcccc
      721 ggaggctccc tcacagctgt tctggcagac attgaagtga tctggtctca tgcaatacaa
      781 aagtatttgg aaatcccact gaaagattta aagtattaca ggtgcatctt gttaattcca
      841 gatatctata acaagcagca tgtgaaagag ctggtccata tgatactgat gaagatgggc
      901 ttcgcaggga ttgtggtcca tcaggagtct gtgtgcgcta cgtttgggag cggcttgagc
      961 agcacctgtg ttgtagatgt tggggaccag aaaacaagtg tgtgctgtgt agaggatggg
     1021 gtgtctcatc ggaacacacg gctttgtctg gcctatgggg gctctgacgt gtcgaggtgt
     1081 ttttactggc tcatgcagcg agcgggattc ccttacagag agtgtcagct gacaaataaa
     1141 atggattgcc tcctcttgca gcaccttaaa gaaacctttt gtcatttaga tcaggatatc
     1201 tccggacttc aggaccatga gtttcagatt cggcatccgg attcccctgc cctgctttac
     1261 cagtttcgat taggagatga aaagctccag gctccaatgg cgctttttta cccagcaacc
     1321 tttgggatcg tgggacagaa gatgaccact ctgcagcaca ggtcccaggg agaccctgag
     1381 gatccccatg atgagcacta cctgctggcc acccagagca agcaagaaca gtctgcaaaa
     1441 gccactgctg accgcaagtc tgcatccaaa cccattggat ttgaagggga tctgcgtggc
     1501 cagtcctctg atcttccaga aagactccat tcccaggagg tggacctggc ttcttctcag
     1561 ggagactgtt tgatggcggg caatgagtcc gaggaagccc tcactgcact gatgtccagg
     1621 aaaactgcaa tctcgctgtt tgaggggaaa gccttgggcc ttgataaggc catcctgcac
     1681 agcgtagact gttgctcatc tgatgatacc aaaaagaaga tgtatagctc tatcctggtt
     1741 gtgggaggcg gtttgatgtt tcataaggct caagagtttc tccagcacag aattctcaac
     1801 aaaatgccgc cttcattcag gcgaattatt gaaaacgtgg atgtgatcac aaggcccaag
     1861 gacatggacc cccggctgat cgcatggaaa ggaggtgcag tactggcgtg tttggacacc
     1921 actcaggaac tgtggattta tcagcgagag tggcaacgct ttggtgtccg aatgttacgg
     1981 gaacgagctg cctttgtgtg gtgaaaacca caaccgagtc tcaggacata aaagacttaa
     2041 agagtgtatg tattgtaagt tattgaccac gaagcttaat tttcctagaa ttaaattaat
     2101 gcaattttat gttaaagtat g
//
