LOCUS       NM_001418135            3194 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ARP1 actin-related protein 1B, centractin beta
            (Actr1b), transcript variant 1, mRNA.
ACCESSION   NM_001418135
VERSION     NM_001418135.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3194)
  AUTHORS   Sacksteder,C.A., Qian,W.J., Knyushko,T.V., Wang,H., Chin,M.H.,
            Lacan,G., Melega,W.P., Camp,D.G. 2nd, Smith,R.D., Smith,D.J.,
            Squier,T.C. and Bigelow,D.J.
  TITLE     Endogenously nitrated proteins in mouse brain: links to
            neurodegenerative disease
  JOURNAL   Biochemistry 45 (26), 8009-8022 (2006)
   PUBMED   16800626
REFERENCE   2  (bases 1 to 3194)
  AUTHORS   Goodson,H.V. and Hawse,W.F.
  TITLE     Molecular evolution of the actin family
  JOURNAL   J Cell Sci 115 (Pt 13), 2619-2622 (2002)
   PUBMED   12077353
REFERENCE   3  (bases 1 to 3194)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084389.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422600.1800474.1,
                                           ERR3363658.5543631.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               AC084389.1         93864-93997
            135-199             AC084389.1         95548-95612
            200-275             AC084389.1         96858-96933
            276-401             AC084389.1         101203-101328
            402-526             AC084389.1         101620-101744
            527-743             AC084389.1         101902-102118
            744-836             AC084389.1         102290-102382
            837-1026            AC084389.1         102480-102669
            1027-1088           AC084389.1         103206-103267
            1089-1129           AC084389.1         103426-103466
            1130-3194           AC084389.1         103625-105689
FEATURES             Location/Qualifiers
     source          1..3194
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 15.38 cM"
     gene            1..3194
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /note="ARP1 actin-related protein 1B, centractin beta"
                     /db_xref="GeneID:226977"
                     /db_xref="MGI:MGI:1917446"
     exon            1..134
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1232
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /note="isoform a is encoded by transcript variant 1;
                     beta-centractin; actin-related protein 1B; ARP1
                     actin-related protein 1 homolog B, centractin beta"
                     /codon_start=1
                     /product="beta-centractin isoform a"
                     /protein_id="NP_001405064.1"
                     /db_xref="GeneID:226977"
                     /db_xref="MGI:MGI:1917446"
                     /translation="MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKH
                     MRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTF
                     SEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDS
                     GDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGADFHTSAEFEVVRTIK
                     ERACYLSINPQKDEALETEKVQYTLPDGSTLDPSSPQVGPARFRAPELLFQPDLVGDE
                     SEGLHEVLAFAIHKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIK
                     ISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF"
     exon            135..199
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            200..275
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            276..401
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            402..526
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            527..743
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            744..836
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            837..1026
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1088
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1129
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..3194
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2092..2097
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /note="hexamer: AATAAT"
     polyA_site      2106
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /note="major polyA site"
     regulatory      3176..3181
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /note="hexamer: AATAAA"
     polyA_site      3194
                     /gene="Actr1b"
                     /gene_synonym="2310066K23Rik; Arp1b"
                     /note="major polyA site"
ORIGIN      
        1 gcatccgtcc aggtctcccc gcgaaccttg tagcccgccg gtcctcctgc agcccgcctg
       61 ctgggcaggg ccggctcggc cgggccatgg agtcctacga catcatcgct aaccagcccg
      121 tggtcatcga caatggttca ggggtgatca aggctggctt tgcaggagac cagattccta
      181 agtactgttt cccaaactat gtcggacggc caaagcacat gcgggttatg gctggagccc
      241 tggaggggga cctgttcatt ggaccgaaag cagaggagca ccgggggctg ctgaccatcc
      301 gataccccat ggaacacggt gtggtacggg attggaatga catggaacgc atctggcagt
      361 acgtctactc taaggaccag ctgcagacct tctctgagga gcatcctgtt cttctaacgg
      421 aggccccact gaaccccagt aagaaccggg agaaggcggc agaggtcttc tttgaaacct
      481 tcaatgttcc tgcactgttt atctccatgc aggccgtgct tagcctgtac gcaacaggac
      541 gcaccacagg agtggtttta gattcggggg acggggtcac tcacgctgtc cccatctatg
      601 agggctttgc catgccacac tccatcatgc gggttgacat tgcgggccgg gacgtctctc
      661 gatatctgag gctgctgcta cgcaaggaag gggcagactt ccacacctca gctgagtttg
      721 aggtggtccg gaccatcaaa gagcgagctt gctatctgtc catcaaccca caaaaggacg
      781 aggctctcga gactgagaag gtgcagtaca cccttccaga cggcagcacg cttgatccgt
      841 cttctccaca ggtggggcct gcgcgcttcc gagcccctga actgctgttc cagccagacc
      901 tggtagggga tgagagtgag ggactccatg aagttctggc cttcgccatc cacaagtctg
      961 acatggacct ccgccggaca ctcttctcca atatcgtgct gtcagggggc tcaacactct
     1021 tcaaaggctt tggagacagg ttactaagtg aagtaaagaa gcttgccccg aaggatgtta
     1081 aaatcaagat ctctgctcct caggaacggc tgtactccac gtggattgga ggctccatcc
     1141 tcgcctcact ggataccttc aagaagatgt gggtatccaa aaaggaatat gaagaagatg
     1201 gctcccgcgc gattcatcgc aaaaccttct aatgcccgag gagggtggac atactgggag
     1261 agagggagaa aaggggagcc agagcccttg accccttttg gtctgggttc atgttctaag
     1321 attagggtcc cctgcatgcc ctgaccccgg agcaggtggt gcgatcatgg tcacctgtag
     1381 ccctcccctc ccctccccct gtgctcaaca cacacacaga cacacacaga gtaatgattg
     1441 gctgcatggc tggcagtccc aagctggagc atcggaactg aggaacccag catcgagctg
     1501 gtgtgagtga ccctcttgca gtgccactgt ggcctgtggt tccttgctct ggccttgaag
     1561 ctctgagacc agactcacat gctccatttg ctctgacagg ctcccaatgg ggctagactc
     1621 cctggatctc tggagtaggc tgaagggagg gacagccagg agctcccctc agggtggtga
     1681 ggcacagtgg tgtttgatgc tgcctcctct ttctggcctg gcagggcaaa tgtcctgcat
     1741 aggactgact aggggacagt cctccatcca ctgagggaat gcagccaaga gtcagagcat
     1801 cagagccatg ggcagccaca gctcgtggtt tgccccactc tctttcaaag cactacactg
     1861 atttgctact ccctcctcgt gccctccgtg ccctggacag gaaggggtta atggtcttta
     1921 tttgctaaag gaaagccatt taatcaggat tcagacccaa agggaaggca tgtgcttacc
     1981 tctatcaaga aaggtcttca ccatgaccag ggcctcccct ccctctccag atctgaacag
     2041 taatttaaca cagttgcctg aaaaatactt gtttttataa atcattatag taataattat
     2101 ggacaaggcc cggtgtgtgg ctctgattct tggggctctg tgctcttgtt tgctcgccca
     2161 tcactgggag tgctgagaga aagaacactg gcagagctca ggagcttgag gcgacaggac
     2221 aggtgagagc agcctcgtac cctcccactg tgacctgcta gggctgctgt gtgtgcctcg
     2281 catgtgtgta ccgcacctcc atgggcccac cgaggtgtgc aggtgctggc agtgatgcag
     2341 gcttagcagc ttacagcagg agaagaagaa ggagaggcag cctgagaatg gaccaggctc
     2401 tacaggaaga aacagaacaa tctgcaggag tcctgcaggc agcaagtaga gaagcttgct
     2461 tgttagtgtg tgggtgcata gtgcacaaca catgattgag gctgatggag gaaacaagat
     2521 acaaagggct catcataaag gagaaagatg ccagccagtt tggaacagtg ttaggccgtt
     2581 agggttaggg ctgcaccatg ctgccttgta agagcttggt cagtggttag ggagagccct
     2641 ttgacaggct ggggagggac agttggcaag gaaggtaaat tggtctgtgg cacagtgaca
     2701 taaaccaaag aggtcagatg gactagcatg tgggggatct gaagaaagga cattaaccgt
     2761 ttgctaggtg acaagttttc actgtggaag agtagtgagc agagccaagt gttgaaagct
     2821 ataggccaaa gcactgatca ggaatgtgtg cagcagatgc tgtgcggcca tgtggtcaca
     2881 gcatcaaagt ttacacagac gcctgtgcta aggggccctg caaaccagct cctgtgcagg
     2941 gtcctgctgg caccatgggc tcccagccac ccgtgtttgg aaccttcctg ctgagctcct
     3001 cgtgcccaca cttgtcagtc taagtctatg ctctacagta tcctgctacc catcctttcc
     3061 tatcggggcc ccagcctcgc ccacgaccct gctccttcct gcccacccag tgtgtgtgct
     3121 cataatctac tgtgcgggta accacctcaa atctgtaatg atttataagc catacaataa
     3181 aatattcatg agtc
//
