LOCUS       NM_183282               1380 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus actin-like 9 (Actl9), mRNA.
ACCESSION   NM_183282
VERSION     NM_183282.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1380)
  AUTHORS   Dai,J., Zhang,T., Guo,J., Zhou,Q., Gu,Y., Zhang,J., Hu,L., Zong,Y.,
            Song,J., Zhang,S., Dai,C., Gong,F., Lu,G., Zheng,W. and Lin,G.
  TITLE     Homozygous pathogenic variants in ACTL9 cause fertilization failure
            and male infertility in humans and mice
  JOURNAL   Am J Hum Genet 108 (3), 469-481 (2021)
   PUBMED   33626338
  REMARK    GeneRIF: Homozygous pathogenic variants in ACTL9 cause
            fertilization failure and male infertility in humans and mice.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CN841548.1,
            BY083809.1, BU583640.1 and BC089487.1.
            
            On Jan 21, 2006 this sequence version replaced NM_183282.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               CN841548.1         4-105
            103-240             BY083809.1         108-245
            241-496             BU583640.1         9-264
            497-592             BC089487.1         1-96
            593-594             BU583640.1         361-362
            595-1380            BC089487.1         99-884
FEATURES             Location/Qualifiers
     source          1..1380
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 17.98 cM"
     gene            1..1380
                     /gene="Actl9"
                     /gene_synonym="1700029I08Rik"
                     /note="actin-like 9"
                     /db_xref="GeneID:69481"
                     /db_xref="MGI:MGI:1916731"
     exon            1..1370
                     /gene="Actl9"
                     /gene_synonym="1700029I08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..1317
                     /gene="Actl9"
                     /gene_synonym="1700029I08Rik"
                     /note="actin-like 7A; actin-like 7-alpha"
                     /codon_start=1
                     /product="actin-like protein 9"
                     /protein_id="NP_899105.2"
                     /db_xref="CCDS:CCDS57063.1"
                     /db_xref="GeneID:69481"
                     /db_xref="MGI:MGI:1916731"
                     /translation="MDVNGHPKFQPSPETDGPLPLTSSTLMVSKSLQQDSLSMVGDRL
                     PPKTGAVVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATKDQSELETFIGEAAR
                     SRPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREK
                     LVEVAFESLHSPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQ
                     RLDLAGNHLTAFLAEMLLGSGFSLQQEDLDLVENIKHHYCYLAPDFQKEQARPDEECK
                     QSLKLPDGRTVTLGKELFQCPELLFHPPEIPGLSPIGLPAMAEQSLLKVPQELRPHVA
                     RNVILCGGSSLFTGLEGRFRAELLHSLSPEDHVVVMAHPNRNLSVWIGGSILASLHAF
                     QSCWVLREQYEERGPQVVYRKCY"
     regulatory      1347..1352
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Actl9"
                     /gene_synonym="1700029I08Rik"
                     /note="hexamer: AGTAAA"
     polyA_site      1370
                     /gene="Actl9"
                     /gene_synonym="1700029I08Rik"
                     /note="major polyA site"
ORIGIN      
        1 cttttctact ggcacccaga gtgaagaggt ccactttgtc aagcagcatt acgaggccat
       61 ctgcagccta tggatgtcaa tggacaccca aagttccagc cctccccaga gactgatggg
      121 cctcttcccc tgacctctag tacactcatg gtgagcaaga gtctacagca agattccctc
      181 agtatggtgg gagacaggct cccaccaaaa actggtgctg tggttattga catgggcaca
      241 ggcacctgta aggtaggctt tgcaggacag tcccaaccca cctacacggt ggccaccatc
      301 ctgggttgcc agcccaagaa acaggctacc aaggaccagt cggagctgga aacttttatt
      361 ggggaggccg cccgctcccg gccagaactg aggttggtga agcctattcg caatggcatt
      421 gtggtggact gggaagctgc ggaactaata tggagacaca tcttggaaca tgatctccaa
      481 gtagccaccc atgagcaccc tctactgttt tcagatccac ccttcagccc tgccaccaac
      541 cgagaaaagc tagtagaagt ggcctttgag tctctgcact ccccagcctt atatgtggca
      601 tctcaatctg tattgtcagt ctatgctcac gggcgtgtca atggacttgt tgtggacacc
      661 ggccatggag tcagctacac ggtgccagtt gttcagggtt acaacctacc ccatgccatc
      721 caacgcttgg acctggcagg aaaccatctt actgccttcc tagcagagat gctcctgggc
      781 tctggcttct cgttgcaaca ggaggacctg gacttggtgg agaacatcaa acatcattac
      841 tgctatttgg ccccagattt ccaaaaggaa caggcccgcc cagatgagga gtgcaagcaa
      901 tccctgaagc ttcctgatgg acggactgtc actctgggaa aggagttatt ccagtgccca
      961 gagctcctat tccatccccc ggagattcca ggattgtcgc ccatcggcct cccagccatg
     1021 gctgaacaga gcctcctcaa ggtgcctcag gagctacggc ctcatgtggc ccggaatgtg
     1081 atactatgcg gaggctcctc actcttcacc ggcctggagg gtcgcttcag ggcagagcta
     1141 ctgcattctc tatcccctga ggaccacgta gtggtgatgg cacaccccaa caggaacctc
     1201 tctgtgtgga ttgggggctc cattctagcc tcattgcatg ctttccagtc ctgttgggtc
     1261 ctacgggaac aatatgaaga aaggggaccc caggttgtat accgaaaatg ctactaacat
     1321 ggggaaaggc gggaagggct aagggcagta aagctttctt ggcaggcaaa aaaaaaaaaa
//
