LOCUS       NM_007391               1067 bp    mRNA    linear   ROD 14-OCT-2024
DEFINITION  Mus musculus acrosomal vesicle protein 1 (Acrv1), transcript
            variant 1, mRNA.
ACCESSION   NM_007391
VERSION     NM_007391.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1067)
  AUTHORS   Suzuki,A., Yabuta,N., Shimada,K., Mashiko,D., Tokuhiro,K.,
            Oyama,Y., Miyata,H., Garcia,T.X., Matzuk,M.M. and Ikawa,M.
  TITLE     Individual disruption of 12 testis-enriched genes via the
            CRISPR/Cas9 system does not affect the fertility of male mice
  JOURNAL   J Reprod Immunol 163, 104252 (2024)
   PUBMED   38697008
REFERENCE   2  (bases 1 to 1067)
  AUTHORS   Dali,O., D'Cruz,S., Legoff,L., Diba Lahmidi,M., Heitz,C.,
            Merret,P.E., Kernanec,P.Y., Pakdel,F. and Smagulova,F.
  TITLE     Transgenerational epigenetic effects imposed by neonicotinoid
            thiacloprid exposure
  JOURNAL   Life Sci Alliance 7 (2), e202302237 (2023)
   PUBMED   37973188
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1067)
  AUTHORS   Reddi,P.P.
  TITLE     Transcriptional regulation of spatiotemporal gene expression within
            the seminiferous epithelium: Mouse Acrv1 gene as a model
  JOURNAL   Andrology 11 (5), 904-910 (2023)
   PUBMED   36793255
  REMARK    GeneRIF: Transcriptional regulation of spatiotemporal gene
            expression within the seminiferous epithelium: Mouse Acrv1 gene as
            a model.
            Review article
REFERENCE   4  (bases 1 to 1067)
  AUTHORS   Dura,M., Teissandier,A., Armand,M., Barau,J., Lapoujade,C.,
            Fouchet,P., Bonneville,L., Schulz,M., Weber,M., Baudrin,L.G.,
            Lameiras,S. and Bourc'his,D.
  TITLE     DNMT3A-dependent DNA methylation is required for spermatogonial
            stem cells to commit to spermatogenesis
  JOURNAL   Nat Genet 54 (4), 469-480 (2022)
   PUBMED   35410378
REFERENCE   5  (bases 1 to 1067)
  AUTHORS   Urekar,C., Acharya,K.K., Chhabra,P. and Reddi,P.P.
  TITLE     A 50-bp enhancer of the mouse acrosomal vesicle protein 1 gene
            activates round spermatid-specific transcription in vivodagger
  JOURNAL   Biol Reprod 101 (4), 842-853 (2019)
   PUBMED   31290539
  REMARK    GeneRIF: A 50-bp enhancer of the mouse acrosomal vesicle protein 1
            gene activates round spermatid-specific transcription in
            vivodagger.
REFERENCE   6  (bases 1 to 1067)
  AUTHORS   Reddi,P.P., Flickinger,C.J. and Herr,J.C.
  TITLE     Round spermatid-specific transcription of the mouse SP-10 gene is
            mediated by a 294-base pair proximal promoter
  JOURNAL   Biol Reprod 61 (5), 1256-1266 (1999)
   PUBMED   10529272
REFERENCE   7  (bases 1 to 1067)
  AUTHORS   Reddi,P.P., Naaby-Hansen,S., Aguolnik,I., Tsai,J.Y., Silver,L.M.,
            Flickinger,C.J. and Herr,J.C.
  TITLE     Complementary deoxyribonucleic acid cloning and characterization of
            mSP-10: the mouse homologue of human acrosomal protein SP-10
  JOURNAL   Biol Reprod 53 (4), 873-881 (1995)
   PUBMED   8547483
REFERENCE   8  (bases 1 to 1067)
  AUTHORS   Lee,C.Y., Wong,E., Hsu,E., Kowalik,T. and Huang,E.S.
  TITLE     Molecular identity of a sperm acrosome antigen recognized by HS-63
            monoclonal antibody
  JOURNAL   J Reprod Immunol 24 (3), 235-247 (1993)
   PUBMED   8230001
REFERENCE   9  (bases 1 to 1067)
  AUTHORS   Liu,M.S., Aebersold,R., Fann,C.H. and Lee,C.Y.
  TITLE     Molecular and developmental studies of a sperm acrosome antigen
            recognized by HS-63 monoclonal antibody
  JOURNAL   Biol Reprod 46 (5), 937-948 (1992)
   PUBMED   1591350
REFERENCE   10 (bases 1 to 1067)
  AUTHORS   Wright,R.M., John,E., Klotz,K., Flickinger,C.J. and Herr,J.C.
  TITLE     Cloning and sequencing of cDNAs coding for the human
            intra-acrosomal antigen SP-10
  JOURNAL   Biol Reprod 42 (4), 693-701 (1990)
   PUBMED   1693291
  REMARK    Erratum:[Biol Reprod 1990 Nov;43(5):following 903]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155921.2.
            
            On Jul 20, 2022 this sequence version replaced NM_007391.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005705.1, BC100459.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               AC155921.2         126772-126878       c
            108-599             AC155921.2         125433-125924       c
            600-719             AC155921.2         123426-123545       c
            720-1067            AC155921.2         121289-121636       c
FEATURES             Location/Qualifiers
     source          1..1067
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.67 cM"
     gene            1..1067
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /note="acrosomal vesicle protein 1"
                     /db_xref="GeneID:11451"
                     /db_xref="MGI:MGI:104590"
     exon            1..107
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..844
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; acrosomal protein SP-10; MSA-63"
                     /codon_start=1
                     /product="acrosomal protein SP-10 isoform 1 precursor"
                     /protein_id="NP_031417.2"
                     /db_xref="CCDS:CCDS22971.1"
                     /db_xref="GeneID:11451"
                     /db_xref="MGI:MGI:104590"
                     /translation="MKELILLGLYLLGSAQGAPPGQPEELLDSVDQQASVQQLSSEYL
                     SLANPSDAEALYETPLDEKTLSGHSSSEQESSEHAVAEHSAGEHSSGEQSSEHMSGDH
                     MSGEHLSEHTSEEHSSGEHTSTEHTSGEQPATEQSSSDQPSEASSGEVSGDEAGEQVS
                     SETNDKENDAMSTPLPSTSAAITINCHTCAYMNDDAKCLRGEGVCTTQNSQQCMLKKI
                     FEGGKLQFMVQGCENMCPSMNLFSHGTRMQIMCCRNEPLCNKV"
     exon            108..599
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            600..719
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            720..1067
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1048..1053
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /note="hexamer: AATAAA"
     polyA_site      1067
                     /gene="Acrv1"
                     /gene_synonym="Msa63; SP-10"
                     /note="major polyA site"
ORIGIN      
        1 agtttcttct cagctcttga gtgtgccaca ttagagatct ttatttacct aaatcaaaat
       61 gaaggagtta atcttactgg gtctttatct gcttggatct gcccaaggag caccaccagg
      121 tcagcctgag gagcttcttg actctgtaga ccaacaagct tcggttcagc aactttcaag
      181 cgagtatctc tcactcgcaa acccttcaga tgccgaggct ttatatgaaa ctcctttaga
      241 tgagaagact ctgagtggtc atagttcaag tgaacaggaa tcaagtgagc atgctgtagc
      301 tgaacattct gcaggtgagc actcttcagg agaacagtct tcagaacaca tgtcaggtga
      361 ccacatgtca ggagagcact tgtcagaaca cacttcagag gagcactcct cgggcgagca
      421 cacttccacc gagcacactt caggtgaaca acctgcaact gaacagtcct caagtgacca
      481 gccctccgaa gcatcttcag gtgaagtttc gggtgacgaa gcaggtgaac aggtgtctag
      541 cgagacaaat gacaaagaaa atgatgctat gagtacacca cttccaagca catctgcagc
      601 cataacaata aattgccaca catgtgctta tatgaatgat gatgcaaaat gtctccgtgg
      661 agaaggagta tgcaccactc aaaactccca gcagtgcatg ttaaagaaga tctttgaagg
      721 tggaaaactc cagttcatgg ttcaagggtg tgagaacatg tgcccatcta tgaacctctt
      781 ctctcatgga acaagaatgc aaattatgtg ctgtcggaat gaacctctct gcaacaaggt
      841 ctagatgccc gtgccctact tcttgctctg acttaggcag gttcaccact ctacttggct
      901 caatttatgt tcaacttcaa caactaatca catcgggctc tgcctgatca ccagataaga
      961 agctcaaacc ttgtctttat tgatacccca ttgcctatgt cctctgcctt actttgctcc
     1021 catccttccg cagatgttct tttttgcaat aaattgctat taaagaa
//
