LOCUS       NM_019800               1756 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus acid phosphatase 6, lysophosphatidic (Acp6), mRNA.
ACCESSION   NM_019800
VERSION     NM_019800.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1756)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1756)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   3  (bases 1 to 1756)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   4  (bases 1 to 1756)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1756)
  AUTHORS   Luquain,C., Singh,A., Wang,L., Natarajan,V. and Morris,A.J.
  TITLE     Role of phospholipase D in agonist-stimulated lysophosphatidic acid
            synthesis by ovarian cancer cells
  JOURNAL   J Lipid Res 44 (10), 1963-1975 (2003)
   PUBMED   12837850
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK165356.1 and AC140071.4.
            
            On Jun 18, 2009 this sequence version replaced NM_019800.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK165356.1, AK077729.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1692              AK165356.1         2-1693
            1693-1756           AC140071.4         125398-125461       c
FEATURES             Location/Qualifiers
     source          1..1756
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 42.04 cM"
     gene            1..1756
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /note="acid phosphatase 6, lysophosphatidic"
                     /db_xref="GeneID:66659"
                     /db_xref="MGI:MGI:1931010"
     exon            1..589
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     CDS             392..1648
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /EC_number="3.1.3.2"
                     /note="acid phosphatase like 1; lysophosphatidic acid
                     phosphatase type 6; PACPL1; acid phosphatase-like protein
                     1"
                     /codon_start=1
                     /product="lysophosphatidic acid phosphatase type 6
                     precursor"
                     /protein_id="NP_062774.2"
                     /db_xref="CCDS:CCDS17653.1"
                     /db_xref="GeneID:66659"
                     /db_xref="MGI:MGI:1931010"
                     /translation="MRVWVPVGVLTSLAYCFHQRRVALAEQRAPNGQRPVDRNLLELK
                     MVQVVFRHGARSPLKPLPLEEQVEWNPKLLEIPPQTRFDYTVTNLAGGPKPHSHYDTE
                     YRKTTLRGGVLAGQLTKVGMQQMFALGEKLRKNYVEDIPFLSPVYNPQEVFIRSTNMF
                     RNLESTRCLLAGLFQHQKGSAVIHTDEASSEVLYPNYQSCWVLKEKTRGRKKAAISQP
                     GISEDLEKVKTGVGINNGDDVDFFVLLDNVAAEQVHSLLNCPALERFAQLIEQRAVDM
                     ALYVVEQEDRESIQMAVGPFLHILEGNLLKTVDPTTAPSKTRKMYLYATHDVTLLPML
                     LALGIFDQKWPPFAVDLTMELYQHQESKEWFVQLFYNGKEQVPRGCPDKLCPLDKFLN
                     TMSVYSVSPEKYRTLCSKTRIVELGE"
     exon            590..718
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            719..849
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            850..926
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1014
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1147
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1248
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1344
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1510
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1756
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1677..1682
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /note="hexamer: AATAAA"
     regulatory      1692..1697
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /note="hexamer: TATAAA"
     polyA_site      1698
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
                     /note="major polyA site"
     polyA_site      1719
                     /gene="Acp6"
                     /gene_synonym="5730559A09Rik; ACPL1; mPACPL1"
ORIGIN      
        1 agacttaatt ggagcaggtc cgtgggaggt caggagattg cgtggggagc ttggttataa
       61 aatgtggacc cgaatcccgg gtgtccgagg aacttctgct tttgcggcct ccccttcaca
      121 cggtttgaag tgcaagtttc aggtccaagt aactgccctg actgagcctg catgcagtag
      181 gggcggccgg cagacgctag gcttaaacta ctagacaatc tttctgctcc cacccctttc
      241 tctccacctc cggcctgact gtcgctgggt cgccccgcta gagtcgcttg ttctgagagc
      301 ttggatgcac ttgccctcca gttcccgcga acttctgagt agctgctgag ccgcgttgcc
      361 tgcggagccc tcagcttcca cagcctccat catgcgcgtg tgggtccccg tgggtgtcct
      421 gacctcgctg gcttactgct tccaccagcg gcgggtggcc ctggccgagc agcgggctcc
      481 taatggccag cgtccggtgg accgcaacct actggagctg aaaatggtgc aggtggtgtt
      541 tcgacacggg gcacggagtc cgctcaagcc tctcccgctg gaggagcagg tggagtggaa
      601 ccccaagctt ttagagatcc cacctcaaac tcggtttgat tacactgtca ccaatctagc
      661 tgggggcccg aaacctcatt ctcattacga cactgaatac cgcaagacca ccttgagggg
      721 tggcgtgctt gctgggcagc tgaccaaggt gggcatgcaa cagatgtttg ccctgggaga
      781 gaaactgagg aagaattacg tggaggatat tcccttcctt tcaccagtct acaaccccca
      841 agaggtcttt attcgctcca ccaacatgtt tcggaatctg gaatctactc ggtgcttgct
      901 ggctggactt ttccaacatc agaaagggtc tgccgtcatc catactgatg aggcaagctc
      961 tgaagtcctg taccccaact atcagagctg ctgggtcctg aaagagaaga ctaggggccg
     1021 gaagaaggct gccatttcgc agccaggcat ctcagaggat ttggaaaagg tgaagaccgg
     1081 ggtgggcatc aacaacggtg atgacgtgga cttctttgtt ctcctggaca acgtggctgc
     1141 tgagcaggta cacagccttc taaactgccc ggccctggag agattcgccc agctgattga
     1201 gcagagggct gtggacatgg ccctgtatgt ggtggaacaa gaagacaggg aaagtatcca
     1261 gatggcagtg ggcccattcc tacacatcct ggaaggaaac ctgctcaaaa ctgtggaccc
     1321 taccaccgca cccagcaaga ccagaaagat gtacctctat gcaacacatg atgtaaccct
     1381 cctgcctatg ctgttggcct tggggatttt tgaccaaaaa tggcccccat ttgctgttga
     1441 cctgaccatg gaactctacc agcaccaaga atctaaggag tggtttgtgc aactctttta
     1501 caatgggaag gagcaggtac caaggggctg ccccgacaag ctctgtccac tggacaagtt
     1561 cttgaacacc atgtcagttt actctgtaag cccagaaaaa taccgaacac tctgctccaa
     1621 aacacgaata gtagaacttg gagagtgact tgtttacaca gacaagttga tttttaaata
     1681 aagtgccttt atataaaaga gcatcatgtt gagatcaaag gggggaggtc tctacatgat
     1741 ttttatttta tgtctg
//
