LOCUS       NM_001195034            1278 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus acid phosphatase 4 (Acp4), transcript variant 1, mRNA.
ACCESSION   NM_001195034 XM_621786
VERSION     NM_001195034.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Liang,T., Wang,S.K., Smith,C., Zhang,H., Hu,Y., Seymen,F.,
            Koruyucu,M., Kasimoglu,Y., Kim,J.W., Zhang,C., Saunders,T.L.,
            Simmer,J.P. and Hu,J.C.
  TITLE     Enamel defects in Acp4R110C/R110C mice and human ACP4 mutations
  JOURNAL   Sci Rep 12 (1), 16477 (2022)
   PUBMED   36183038
  REMARK    GeneRIF: Enamel defects in Acp4(R110C/R110C) mice and human ACP4
            mutations.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  AUTHORS   Choi,H., Kim,T.H., Yun,C.Y., Kim,J.W. and Cho,E.S.
  TITLE     Testicular acid phosphatase induces odontoblast differentiation and
            mineralization
  JOURNAL   Cell Tissue Res 364 (1), 95-103 (2016)
   PUBMED   26547858
  REMARK    GeneRIF: ACPT inhibits cell proliferation through
            beta-catenin-mediated signaling in dental mesenchyme but elicits
            odontoblast differentiation and mineralization by supplying
            phosphate during dentin formation.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC152939.2.
            
            On Aug 18, 2010 this sequence version replaced XM_621786.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               AC152939.2         15394-15501         c
            109-213             AC152939.2         15211-15315         c
            214-300             AC152939.2         15047-15133         c
            301-447             AC152939.2         14146-14292         c
            448-546             AC152939.2         13468-13566         c
            547-642             AC152939.2         13293-13388         c
            643-775             AC152939.2         12499-12631         c
            776-858             AC152939.2         12328-12410         c
            859-986             AC152939.2         11841-11968         c
            987-1165            AC152939.2         11575-11753         c
            1166-1278           AC152939.2         11384-11496         c
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.77 cM"
     gene            1..1278
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /note="acid phosphatase 4"
                     /db_xref="GeneID:100503991"
                     /db_xref="MGI:MGI:3644563"
     CDS             1..1278
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /EC_number="3.1.3.2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; testicular acid phosphatase; acid phosphatase,
                     testicular"
                     /codon_start=1
                     /product="testicular acid phosphatase isoform 1 precursor"
                     /protein_id="NP_001181963.1"
                     /db_xref="CCDS:CCDS57546.1"
                     /db_xref="GeneID:100503991"
                     /db_xref="MGI:MGI:3644563"
                     /translation="MAEPGSQGHTVGPLLLLLLLLLPRALPEGPLLFVALVFRHGDRA
                     PLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPEYKREEVY
                     IRSTDFDRTLESAQANLAGLFPEAAPGSPETDWKPIPVHTVPVSEDKLLRFPMRSCPR
                     YHELLRESTEAADYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWKVLDTLICQRAHG
                     LDLPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRTQRLG
                     LPLKMVMYSAHDSTLLALQGALGLYDGNTPPYAACMAFEFRGSSREPEEEDGENVTVS
                     LIYRNDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPATVP
                     LLAGAVAVLAVLSLGLGLLAWRPRCLRALGGTV"
     exon            1..108
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            109..213
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            214..300
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            301..447
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            448..546
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            547..642
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            643..775
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            776..858
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            859..986
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1165
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1278
                     /gene="Acp4"
                     /gene_synonym="Acpt; EG546967; Gm1432"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctgagc ccgggtctca gggccacacc gtcggaccct tgctgctgct gctgttgctg
       61 ttgctgcctc gggccctgcc ggaggggccc ctgttatttg tggctctggt gttccgacat
      121 ggcgaccggg ccccactggc ctcctacccc acagatccac acaaggaagc tgcctccacc
      181 ttgtggcctc gaggcttggg ccaactgact aaggagggga tccgccagca gctagaactg
      241 ggccgatttc tgaggaggcg ttacaaggct ttcctgagcc ctgagtacaa gcgagaagag
      301 gtgtacatcc gcagcacaga ctttgaccgg acattggaga gtgcacaagc caacctggct
      361 gggctcttcc ctgaggctgc ccctggaagt cctgagactg actggaagcc cattccagtg
      421 cacacagtgc ctgtgtctga ggacaagttg ctgaggttcc ccatgcgcag ctgtcctcga
      481 taccatgagc tgttacgaga gtccacagag gcagctgact accaggaggc cctggagggc
      541 tggacggact tcctgacccg cctgggcaac ttcactgggc tgtccctggt tggagagcca
      601 ctccggagag catggaaagt tctggatacc ttgatctgcc agcgtgccca tggtcttgac
      661 cttccatcct gggcctctcc agatgtcttg aggactctgt cacagatttc tgctctggat
      721 atcagggccc atgtaggccc accccgagca gcagaaaagg cccagctgac aggggggatc
      781 ctgctggatg ctattctcag caatttctcc cggacccagc gccttgggtt gcccctcaag
      841 atggtcatgt actcagctca tgacagcacc ctgctggccc tccagggggc cctgggcctc
      901 tacgatggga acaccccacc ttacgctgcc tgcatggcct ttgaattccg ggggagctcc
      961 agggaacccg aggaggaaga tggagagaat gtcactgtct ctctcatcta ccgcaatgac
     1021 acctcccgcc cacccctgcc actcagggtc cctgggtgcc cagctccctg tccacttggg
     1081 cgcttccagc agctgactgc tccagcccgg cctccagccc atggggcccc ctgccatggt
     1141 tcttatgagc ctgccagccc cccagccacg gtgcccctgc tggccggagc tgtggctgtg
     1201 ctggccgtgc taagcctggg gcttggtctt ctggcctgga ggcccagatg cctgcgggcc
     1261 ctgggaggga ctgtgtga
//
