LOCUS       NM_001357018            4167 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus acyl-Coenzyme A oxidase 3, pristanoyl (Acox3),
            transcript variant 2, mRNA.
ACCESSION   NM_001357018 XM_006504198
VERSION     NM_001357018.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4167)
  AUTHORS   Yubero P, Hondares E, Carmona MC, Rossell M, Gonzalez FJ, Iglesias
            R, Giralt M and Villarroya F.
  TITLE     The developmental regulation of peroxisome proliferator-activated
            receptor-gamma coactivator-1alpha expression in the liver is
            partially dissociated from the control of gluconeogenesis and lipid
            catabolism
  JOURNAL   Endocrinology 145 (9), 4268-4277 (2004)
   PUBMED   15178647
REFERENCE   2  (bases 1 to 4167)
  AUTHORS   Tanaka K, Tamura H, Tanaka H, Katoh M, Futamata Y, Seki N,
            Nishimune Y and Hara T.
  TITLE     Spermatogonia-dependent expression of testicular genes in mice
  JOURNAL   Dev Biol 246 (2), 466-479 (2002)
   PUBMED   12051830
REFERENCE   3  (bases 1 to 4167)
  AUTHORS   Knoll A, Salles J, Sargueil F, Cassagne C and Garbay B.
  TITLE     Peroxisomal beta-oxidation enzyme gene expression in the developing
            mouse brain
  JOURNAL   Neurosci Lett 285 (3), 201-204 (2000)
   PUBMED   10806321
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122871.4.
            
            [WARNING] On Nov 27, 2023 this sequence was replaced by
            NM_001357018.2.
            
            On Oct 14, 2017 this sequence version replaced XM_006504198.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ278430.1, SRR7974084.5276.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-286               AC122871.4         168158-168443       c
            287-386             AC122871.4         167502-167601       c
            387-541             AC122871.4         163164-163318       c
            542-775             AC122871.4         162625-162858       c
            776-850             AC122871.4         162227-162301       c
            851-940             AC122871.4         161694-161783       c
            941-1084            AC122871.4         159258-159401       c
            1085-1173           AC122871.4         157079-157167       c
            1174-1270           AC122871.4         153066-153162       c
            1271-1453           AC122871.4         151603-151785       c
            1454-1576           AC122871.4         149852-149974       c
            1577-1697           AC122871.4         148436-148556       c
            1698-1820           AC122871.4         146741-146863       c
            1821-1934           AC122871.4         146157-146270       c
            1935-2050           AC122871.4         144280-144395       c
            2051-2225           AC122871.4         143045-143219       c
            2226-2293           AC122871.4         142390-142457       c
            2294-2380           AC122871.4         141655-141741       c
            2381-4167           AC122871.4         137676-139462       c
FEATURES             Location/Qualifiers
     source          1..4167
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 18.32 cM"
     gene            1..4167
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /note="acyl-Coenzyme A oxidase 3, pristanoyl"
                     /db_xref="GeneID:80911"
                     /db_xref="MGI:MGI:1933156"
     exon            1..286
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            287..386
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            387..541
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     CDS             398..2500
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /EC_number="1.3.3.6"
                     /note="isoform a is encoded by transcript variant 2;
                     pristanoyl-CoA oxidase; peroxisomal acyl-coenzyme A
                     oxidase 3; BRCACox; branched-chain acyl-CoA oxidase"
                     /codon_start=1
                     /product="peroxisomal acyl-coenzyme A oxidase 3 isoform a"
                     /protein_id="NP_001343947.1"
                     /db_xref="CCDS:CCDS19232.1"
                     /db_xref="GeneID:80911"
                     /db_xref="MGI:MGI:1933156"
                     /translation="MGSLPEEKDSALWSDTPKGPLSAYRARASFNSGELLLFWDGQDV
                     IHFKKTIFSTLENDPLFARSYGADLPLEKLRELNFLRCKRVFEYGFFKVEELLKNPLK
                     ILVLINCLGMYDWSLANKCVLHMLVFGTTVFVSGSEKHFKYLEKIYSLEIFGCFALTE
                     LSHGSNTKAMRTTAHYDPDTQEFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYMPDG
                     QCHGLHSFLVQIRDTKTLLPMTGVMVGDIGKKLGQNGLDNGFAMFNKVRIPRQNLLDR
                     TGNITSEGTYNSPFKDVRQRLGASLGSLSSGRISIISMSVVNLKLAVSIAIRFSATRC
                     QFGPTDKEEIPVLEYPLQQWRILPYLAAAYALDHFSKTIFMDLIEVQSARLRGDHSDQ
                     QAELGREIHALASAGKPLASWTAQRGIQECREACGGHGYLAMNRFGDLRNDNDPNCTY
                     EGDNNVLLQQTSNYLLSLLEPPLQDGAHFTSPLKTVDFLEAYPGILGQKFLGSSKADW
                     MDSAAPLAAYRWLVCYLLQESHRRYCQEKKSRGSDFEARNNSQVYGCRPLALAFMELT
                     VMQRFHEHIHSSGLSPSLRTVLGRLSTLYGLWCLSQHMALLYRGGYISGEQTGRAMED
                     AILTLCEQLKDDAVALVDVIAPSDFVLNSPIAKADGELYKNLWAAVLQQNGVLERAAW
                     WPEFSANKSVADRLKSQL"
     exon            542..775
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            776..850
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            851..940
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1084
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1173
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1270
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1453
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1576
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1697
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1820
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1821..1934
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            1935..2050
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2225
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            2226..2293
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2380
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
     exon            2381..4167
                     /gene="Acox3"
                     /gene_synonym="EST-s59; PCOX"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accagcttgc tccgccctca gaagtcagga tattcctgat aaatagtgtc ctccagacgc
       61 cgggttgact aggaccacga atcccaagct ggatccggga ggtgaggacg tgccgggccc
      121 gggagattcc agacaggaag ggtttgcagg agctcaggct ggggtgactg ctggcgtttg
      181 cactctgcct gacatcatac tcgctagcgg gagaacgaac tgaccgcagc tttttacaat
      241 ctgctcggcg gccgggaggt atcccaagac agaacaaagt tagcttgaac atcacaagtg
      301 cctgatttga gtcccaggaa cgtggcagac actgccccgt gtgcagagtt atcgttgctt
      361 ctgagaaacg gggacaaagc aggtcggtga cagtaccatg ggatccctac cggaagaaaa
      421 agacagtgct ttgtggtcag acacccccaa gggccctctt agtgcctacc gagcaagagc
      481 ctccttcaac tctggggagc tgctgctctt ttgggacggc caggatgtaa tccacttcaa
      541 gaaaaccatc ttctcaactt tggagaatga ccctctcttt gcccgctcgt acggggccga
      601 cctgccccta gagaagctac gagaactgaa cttccttcgc tgcaagaggg tctttgagta
      661 tggcttcttc aaagtagagg aactgctaaa gaaccccctg aagattctag tgctgattaa
      721 ctgcctgggc atgtacgact ggtccctggc caacaaatgc gtcctccaca tgttggtttt
      781 tggaaccaca gttttcgttt ctggttctga gaagcatttc aagtaccttg agaagatcta
      841 tagcctggag atttttggct gttttgctct caccgaactg agtcatggga gtaataccaa
      901 ggccatgcga acgacagctc actatgatcc tgatactcag gaattcatct tacattcccc
      961 ggatttcgag gctgccaaat tttgggtggg caacctgggc aagacggcaa ctcatgcggt
     1021 ggtgtttgcc caactgtaca tgccagacgg ccagtgccac gggctgcatt ccttcctggt
     1081 gcagatccgt gacacgaaga ccctgcttcc catgacgggg gtgatggtcg gtgacattgg
     1141 gaagaagctg gggcagaatg gcctggataa tggattcgcc atgttcaaca aagttcgaat
     1201 tcctcgccag aacctgctgg acaggactgg gaatatcacc tctgagggca cttacaacag
     1261 cccctttaag gatgtccggc agcgtttggg cgcatcattg ggcagcctgt cctcaggacg
     1321 catctccatc atcagcatgt ctgtggtcaa cctgaagctg gccgtgtcca tagccatccg
     1381 gttctcggcc acacggtgtc agtttggacc cacggataag gaagagattc ctgtccttga
     1441 atatccactg cagcaatggc gcatacttcc gtacctggcg gctgcctatg ccttggacca
     1501 cttctctaag acaatcttca tggacttgat agaggtgcag agtgcccggc tcaggggaga
     1561 ccacagcgac cagcaggcag aactcggacg tgagatccat gctctggcat cggctggcaa
     1621 gcctctagcc tcatggacag cccagcgggg tatccaggag tgccgtgagg cgtgtggggg
     1681 acatggctac ctggccatga accggtttgg tgacctcaga aacgacaacg acccaaactg
     1741 tacctatgaa ggtgacaaca atgtcctgct gcagcagacc agcaactacc tgctcagcct
     1801 cctggagcct cctctccaag acggagctca cttcacaagc cctctcaaga ccgtggactt
     1861 tctggaagcc tatcctggaa tcttgggcca gaagttcctg ggctccagca aggctgactg
     1921 gatggactca gcagcccccc tggcagccta ccgctggctt gtttgctact tgctccaaga
     1981 gagccatcgg agatactgcc aagagaaaaa gtccagaggc agtgactttg aagcaagaaa
     2041 caacagccag gtgtacggct gccggcccct ggccctggcc ttcatggaac tcaccgtgat
     2101 gcagcgattc cacgaacata tacacagctc cggtctgtct ccatctctgc ggactgtgct
     2161 cgggcggctc agcacgctct acggcctgtg gtgcctgagc cagcacatgg ccctgctcta
     2221 ccgaggtggc tacatttctg gggaacaaac aggaagagcg atggaggacg ccatcctgac
     2281 cctgtgtgag cagctgaaag acgatgcggt ggccttggta gatgtcatcg ccccctccga
     2341 ctttgttctg aactccccaa ttgccaaagc tgatggtgag ctctataaaa acctgtgggc
     2401 agctgtcctg cagcagaatg gtgtgctaga gcgtgccgcc tggtggcccg agttctctgc
     2461 caacaaatct gtagccgaca ggctaaagtc ccagctgtag acacagttgg aggggcggtt
     2521 acagcaggaa cagctgatcc agaggcctgg acccagacac agagctccaa gagacaccca
     2581 gatgcctacg ctgaaaacca ctgacattac agcttctcct cgaccctggt cagcctgttg
     2641 tacccatcct caaatggggt atttgcgagg gatttgcaca gtgtgtctcc ctgagggcct
     2701 tggaatttaa caaaggactt agttatgcta tctcagggct cagataggaa ggtaaagtca
     2761 gggctcacaa tgaaagcctt ctgctgaagt gaactttggg atccgtggaa gatttttgag
     2821 acacactctt ctctctgctg ctgtctgatt ctttaaccct gctgtggggt ggccatactt
     2881 ctctatacct gccatttact cctctgtacc atgaaccatc agaatgatgt aatttgaaga
     2941 tctttatggg gaaaaaaatg ttttattaac tcctctggtg gcaccagaag tttccgctga
     3001 gaaaaatgct cccacagaag acgtgcatgg tggtggggac cacagacaca tcccgctgtg
     3061 tcagtgactg cttggcagtg gctttcatcc ttcagcaaat tcacacacgg catgaccctg
     3121 ctacactggc catagccaga ccctcgtact tctgaaagac atagatgcca ccccttcctg
     3181 ccataggcag gatcccacac cattcgcttt ctgatgggct gttctgagcc ccaggcgctt
     3241 gctcagcctg agagcctctc tcttcaccac ctgttcttct tggtcataca cacacaccgc
     3301 cctggctcag catcctccca gagtcctacc ccagttgaat aggggcctgc cagctggagt
     3361 ccctgtaaaa catgagagcc atgtgtccac agatgacgcc ttccacctgg atccatggct
     3421 tttcccaaca acgaggacta ggtcttaggt ccttttgggt cctcgctgct cttggaatct
     3481 ctaccctccc accctgccag gcagtggtca cctcagccac ctatttatct gaccatactt
     3541 ttgcatggga gcttggttac tgtactgtct gattggagac tgaccagtat gtcacaagaa
     3601 gtgtccacgg ccagtagaat gctgcattaa gatacgtcac atggtcccca gggtcaggca
     3661 gccctctggt ggccaaggtg ccagcagatt tcaaagtata gacaaatgga tctttagcta
     3721 tagcttctga gaggagggag agtcagtttt ctttaagagc cactggtatg ttgagcatgc
     3781 tccattgcgt gcccacacac gcaagagcat atgggtggca cagagtggac ttgatggctt
     3841 ttttttgtct tgtaatatgt gcacatatat gttttcatat ctaccaactg ggtatatctt
     3901 ggtctctggg gtagggactg gctctctgga caaccagact tagatgggtg atatcacatg
     3961 acttctagaa atgaatggtg tatcctggtc cctgctcctg tgtgtgtata ctcccctcct
     4021 cagtcccaag ggtgaggcag gtggcatgtg ggggcctatg ggtagaggct acattattga
     4081 aacaaacttg aaaaggtccc ataaaaatga aacatttgta agcagcagga aagacttgaa
     4141 taattgcaat aaagtgttga aattgaa
//
