LOCUS       NM_001164565            5048 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus acyl-coenzyme A amino acid N-acyltransferase 1
            (Acnat1), mRNA.
ACCESSION   NM_001164565 XM_131433 XM_899543 XM_908003 XM_920683
VERSION     NM_001164565.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5048)
  AUTHORS   Hunt,M.C. and Alexson,S.E.
  TITLE     Novel functions of acyl-CoA thioesterases and acyltransferases as
            auxiliary enzymes in peroxisomal lipid metabolism
  JOURNAL   Prog Lipid Res 47 (6), 405-421 (2008)
   PUBMED   18538142
  REMARK    Review article
REFERENCE   2  (bases 1 to 5048)
  AUTHORS   Reilly,S.J., O'Shea,E.M., Andersson,U., O'Byrne,J., Alexson,S.E.
            and Hunt,M.C.
  TITLE     A peroxisomal acyltransferase in mouse identifies a novel pathway
            for taurine conjugation of fatty acids
  JOURNAL   FASEB J 21 (1), 99-107 (2007)
   PUBMED   17116739
REFERENCE   3  (bases 1 to 5048)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772310.27.
            
            On or before Sep 3, 2009 this sequence version replaced
            XM_908003.2, XM_920683.2, XM_131433.6, XM_899543.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ469311.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-466               AL772310.27        38636-39101         c
            467-669             AL772310.27        37088-37290         c
            670-5048            AL772310.27        31524-35902         c
FEATURES             Location/Qualifiers
     source          1..5048
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 26.46 cM"
     gene            1..5048
                     /gene="Acnat1"
                     /note="acyl-coenzyme A amino acid N-acyltransferase 1"
                     /db_xref="GeneID:230161"
                     /db_xref="MGI:MGI:2140197"
     CDS             1..1251
                     /gene="Acnat1"
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /product="acyl-coenzyme A amino acid N-acyltransferase 1"
                     /protein_id="NP_001158037.1"
                     /db_xref="CCDS:CCDS51174.1"
                     /db_xref="GeneID:230161"
                     /db_xref="MGI:MGI:2140197"
                     /translation="MMIKLIATPSNALVDEPVSIRATGLPPSQIVTIKATVKDENDNV
                     FQSQAFYKTNEAGEVDLEKTPALGGDYVGVHPMGLFFSLKPKKAFHRLMKKDVMNSPF
                     CICLDLYDSVNWLETVRIPSKASQRVQRWFVGPGVKREQIQEGRVRGALFLPPGKGPF
                     PGIIDLFGVIGGLVEFRASLLASHGFAVLALAYFAYKDLPEKLQEVDLEYFEEAANFL
                     LSHPKIQQPGIGVISTSKGAEIGLAMACYLKQVIATVCINGATTTTAVPLRYQDLVVT
                     PIQQALERMEVHVSGAVCFRHTTQYLQNKNILPVEKAQGKILFIVGENDELLDSKLHA
                     QRAMDRLRRHGRSSGRMLAYPGAGHLIEPPYSPLCFASWQPVLGRPMCFGGDLMAHAA
                     AQEHSWREIQKFFRKHLLQSGSKL"
     exon            1..466
                     /gene="Acnat1"
                     /inference="alignment:Splign:2.1.0"
     exon            467..669
                     /gene="Acnat1"
                     /inference="alignment:Splign:2.1.0"
     exon            670..5048
                     /gene="Acnat1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5020..5025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acnat1"
                     /note="hexamer: AATAAA"
     polyA_site      5043
                     /gene="Acnat1"
                     /note="major polyA site"
ORIGIN      
        1 atgatgatca agttgatagc cacaccttca aatgcccttg tggatgagcc tgtgtccatt
       61 cgagcaacag gcctgcctcc atcgcagata gtgaccatca aggcaacagt gaaagatgaa
      121 aatgacaatg tgttccaatc ccaagccttc tacaagacta acgaggctgg tgaggtggac
      181 ctggagaaga caccggcctt ggggggtgac tatgtagggg tccacccaat gggcctcttt
      241 ttctctctga aacccaagaa ggctttccat aggctgatga agaaagatgt gatgaacagc
      301 cccttttgca tctgtttgga cctgtacgac tctgttaact ggctagaaac agtcaggatt
      361 ccatccaagg ccagccagag agtgcagcgc tggtttgttg gccctggggt taagcgggaa
      421 cagattcaag aaggtcgggt tcggggagcc ctttttctcc ctccagggaa aggtcctttc
      481 ccaggaatta ttgatttgtt tggtgtcatt gggggtctag ttgaatttcg tgccagtctt
      541 ttggcttccc atggctttgc agtgctggcg ttggcgtatt ttgcctataa agacctgcct
      601 gagaaactgc aagaggtgga cttggagtat tttgaagaag ctgccaactt cctactatct
      661 caccccaaga tccaacagcc aggaattggt gtgatctcca cgagcaaagg agcagagatt
      721 gggctagcta tggcctgtta cctgaagcag gtgattgcca cggtctgcat aaatggggcc
      781 accaccacca cagccgtccc actaagatac caggatctgg ttgtgacacc catccaacag
      841 gctctggaac ggatggaggt ccatgtttca ggggctgtat gcttccgtca cactacacaa
      901 tatctccaga ataagaatat acttcccgtg gaaaaggccc aggggaagat cctcttcatt
      961 gtgggagaga atgatgaatt gttggatagc aagttacatg cacagagggc catggaccgg
     1021 ctccggaggc atggaagaag cagtggaagg atgctggcat accctggggc aggccacctc
     1081 atagagccac cttattctcc cctttgcttt gcatcctggc aacctgtcct gggtcgaccc
     1141 atgtgttttg gaggagatct catggctcac gcagcagccc aggaacactc ctggagagag
     1201 atccaaaagt tcttcaggaa acacctcctt caatccggaa gcaaactcta aatagagtgt
     1261 ccatgccaga gtaaagtgct gtagcgaaaa tgctggaatt gttgtaggga taaaaacatc
     1321 agatgggaat tgctgggaaa gggtagggat gggggtcaga attctcctgg ctttcttttt
     1381 tttttttttt tttttttttt tttctcctgg ctttcttaca ctcacattca caccaattcc
     1441 attggaagga aatgagataa acgaaaagac caagatacac gtgcatctga tatgttcctg
     1501 ataaatctgt atgtagtttg caattttctt ttctgttttt taacggtcac aagaagtttt
     1561 tggttttgtt tttgattttt aatctttttt tttatagctc agatttcatt cccctcctgg
     1621 accaccttct gactgttcca tatcccatac ctttccctaa cctcccatct ccattaggat
     1681 gtccccagtc acaagcccct gacccatcag acctccccac tccctggggc ctcaagtctc
     1741 ttgagggtca gttaggtgca tcttctctga ctgagtccag acccaccagt cctctactat
     1801 atatgtagtg ggggcctcat atcagctgat gcaggctgct ggttggtggt ccagtgtttg
     1861 agatatctca ggagttcagg ttagttgaaa ctgctggtcc tcctacagag ttgccctcct
     1921 caccttcttc cagcttttct ctaattcaac cacaggagtc agcagcttct gtccattggt
     1981 tgggtgcaaa tatctgcatc tgactctttc agcttcttgt tgagtctttc agagggcagt
     2041 catgatagga ccctgtttgt aagcacacca cagcatcagt aatagtgtca ggccttgggg
     2101 cctcccccta ggctggaatc tattttggac ctgtagctgg acttcatttt cctcaggctc
     2161 atcttccttt ttgtctctgc agttctttca gacaggaaca attatgggtc agagtttttg
     2221 actgtgggtt ggcaactcca tccctcactg gatgccctgt ctttctcctg gaggtgggtt
     2281 ctacacgttc ccttttcccg ctgttgggca tttcatctaa gctgcctccc tttgagtcct
     2341 gagattctct cacctcccag gtctctggta cattctggag gatccctgca cctctttctt
     2401 cccaaggttg tttgtttcta ttctctctga taaccccgag ggcttctccc caccccaaat
     2461 acctgatcat atcacccctt tctcctccca gtccccattc cctcccaggt ccttcccttc
     2521 ctcccctctc ctgtgattgt tttctttccc ctcccaagtg ggattgaggt gtcctcactt
     2581 gggtcttttg acttgttaac attttttagt tctttggatc atatcctggg tattctgcac
     2641 attttttggg ggggtgctaa tatcaaccta ttagtgagta cataccatgc atgtcctttt
     2701 gagtctgagt cacctcactc agaatgattt ttctagttcc atccatttgc ctgcaaaaca
     2761 cagtatgtcc ttacccctaa tagctgagta gtattccgtt ctgtaaatga accacatttt
     2821 ctgtatccat ttttctgttg tgggacttct gggttgtttc cagcttctgg ctatcacaaa
     2881 caagtcctct gtgaacatag tggaacatgt acccctgtgt catggttgga gcatcttttg
     2941 ggtatatacc caagagtggt acagctgaac ctttaggtag atctatttcc aattttctga
     3001 ggaacctcca gattgatttt ccagagtgct tgtactagtt tgcaatccca acagcaatgg
     3061 aggagtgttc cttttcagca catccttgcc aacatgtgct gttatctgag gttttgatct
     3121 tagccattca gattggtgta aggtagaatc tcagggtttt gatttacatt tccctgatca
     3181 ctaaagactt tgaacatttc tttaagtgct tctcagcctt tcaagaatcc tctgttggga
     3241 attctctctt tagttctgca ccccattttt tgattgggtc gtttgctttt ttggtggtta
     3301 gattcttgcg ttctttatat tttttggata ttagctctct atcagatgtg gggttagtga
     3361 aaattttgtt tcctaatctg taggttatgg attttcccta ttgactgtgt cctttgccta
     3421 cagaaacttt tcagtttcat gaggtcccat ttatcagttc ctgatcttag agcataagcc
     3481 actggagttc tgtttaggaa atttcccctg tgccaatggg ttcaaagctc tttcccactt
     3541 tctgttatat tagattcagt gtatctggtt ttatgttcag gtccttgatg tactgggact
     3601 tgagctttgt gtaaggtgac aaatatggat ctattttcat ctttctacat atagactacc
     3661 agttcaacca gcaccatttt ttgaagattt ttttccattg tatatttttg ctgtctttgt
     3721 caaagatcaa gggtgcataa gtgtgtggtt ttatatctgg gtcttcagtt ctattccatt
     3781 gatcaatgtg tctgtctcta taccactaat tttaattatt tttggttgca aggtgtctta
     3841 ctcaaggttt ttattcctgc actaacatca taaccaagaa acagtgggga ggaaaggttt
     3901 atgcagctta cactttccac attactctct gaaaacactt cccagaatat ttcacctcaa
     3961 tgatgctggt ctcttcttaa tcacagctaa tttcttagct ccagctaacc agcatcaata
     4021 gtcccagtaa tgcaaggttt tcactttagt agttctggta tcttgttaat cacagccaac
     4081 tcttcagccc cagctaacca gaaccataga atcttcacaa tcaaatacca atggctctgt
     4141 gaagagtctt taatcttccc tctgaaattt cacaagccag gcctccatct tctgcactgt
     4201 tctcaacatt atcttccaaa ctcctacata acatttgaca gagcccttaa cacgaaatgg
     4261 atcttctagc ccaaagttcc actttatcat agaaataccc cactcagctg gtaccaattt
     4321 gccttagtca tggtttctat tcctggacaa aacataatga ccaagaagca gttggggagg
     4381 aaagggttta ttcatctcac actttccaca ttgctgttga tcaccaaagg atgtcaggac
     4441 tgaaattcaa gcaagccagt aagtaacatc cctccatggc ctctgcatca gctcctgctt
     4501 cctgacctgc aattatacaa agggcatcct acattttcag gtttggcctg ccttccaatc
     4561 tcttgtcaaa ttcaagttgc taaaataaaa tatacggtgg gtcttggatt cttcatttag
     4621 acatgtttta agaagttttg tagacacact ctaaacagaa tggaaagtaa cacccacaca
     4681 ctgcaactga agaattcccg cttctaagaa gataaaagga taaaggacca gcatccacag
     4741 gaagagaaca ttcctcagta acttgggaca agtttcctgt acatcgtata ttgaaattga
     4801 tttacaaatc cacaaaaagg acttttaata aaagcagctg acaaaagaac tatcaacgtc
     4861 atggtaaaac agccgtatct gttcatacta ttctgtggta gaagtctgac atagaaccat
     4921 aggaaaatgc ccttattgtt acattcttga actttgtaaa atgaacaaac aaacaaacag
     4981 aaaatcaact tatagtctaa ttgtttcaat tcttactaaa ataaacaaaa gactgaaatg
     5041 agatataa
//
