LOCUS       NM_023190               4751 bp    mRNA    linear   ROD 28-AUG-2024
DEFINITION  Mus musculus apoptotic chromatin condensation inducer 1 (Acin1),
            transcript variant 2, mRNA.
ACCESSION   NM_023190
VERSION     NM_023190.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4751)
  AUTHORS   Tang,Y., Ni,A., Sun,L., Li,S. and Li,G.
  TITLE     Analysis of the Upregulated Expression Mechanism of Apoptotic
            Chromatin Condensation Inducer 1 in Hepatocellular Carcinoma Based
            on Bioinformatics
  JOURNAL   Turk J Gastroenterol 35 (4), 307-315 (2024)
   PUBMED   39128105
  REMARK    GeneRIF: Analysis of the Upregulated Expression Mechanism of
            Apoptotic Chromatin Condensation Inducer 1 in Hepatocellular
            Carcinoma Based on Bioinformatics.
REFERENCE   2  (bases 1 to 4751)
  AUTHORS   Lin,Y.C., Lu,Y.H., Lee,Y.C., Hung,C.S. and Lin,J.C.
  TITLE     Altered expressions and splicing profiles of Acin1 transcripts
            differentially modulate brown adipogenesis through an alternative
            splicing mechanism
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1863 (9), 194601 (2020)
   PUBMED   32629174
REFERENCE   3  (bases 1 to 4751)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 4751)
  AUTHORS   Hasegawa,M., Kurata,M., Yamamoto,K., Yoshida,K., Aizawa,S. and
            Kitagawa,M.
  TITLE     A novel role for acinus and MCM2 as host-specific signaling
            enhancers of DNA-damage-induced apoptosis in association with viral
            protein gp70
  JOURNAL   Leuk Res 33 (8), 1100-1107 (2009)
   PUBMED   19058849
  REMARK    GeneRIF: gp70 enhances cellular DNA-damage-induced signaling in
            association with host-specific cellular proteins including acinus
            and MCM2 resulting in the activation of DNA-PK to phosphorylate
            P53.
REFERENCE   5  (bases 1 to 4751)
  AUTHORS   Vucetic,Z., Zhang,Z., Zhao,J., Wang,F., Soprano,K.J. and
            Soprano,D.R.
  TITLE     Acinus-S' represses retinoic acid receptor (RAR)-regulated gene
            expression through interaction with the B domains of RARs
  JOURNAL   Mol Cell Biol 28 (8), 2549-2558 (2008)
   PUBMED   18250153
REFERENCE   6  (bases 1 to 4751)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 4751)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 4751)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   9  (bases 1 to 4751)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   10 (bases 1 to 4751)
  AUTHORS   Sahara,S., Aoto,M., Eguchi,Y., Imamoto,N., Yoneda,Y. and
            Tsujimoto,Y.
  TITLE     Acinus is a caspase-3-activated protein required for apoptotic
            chromatin condensation
  JOURNAL   Nature 401 (6749), 168-173 (1999)
   PUBMED   10490026
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF168782.1, AK011698.1, AK030449.1 and BC094217.1.
            
            On Jul 24, 2008 this sequence version replaced NM_023190.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and 5'
            coding region, compared to variant 1. The resulting isoform (2) is
            longer and has a distinct N-terminus, compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF168782.1, SRR11927934.2648331.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AF168782.1         1-86
            87-158              AK011698.1         50-121
            159-480             AF168782.1         160-481
            481-486             AK011698.1         443-448
            487-540             AF168782.1         488-541
            541-1001            AK011698.1         503-963
            1002-2563           AK030449.1         695-2256
            2564-2837           AF168782.1         2565-2838
            2838-2838           BC094217.1         484-484
            2839-3747           AF168782.1         2840-3748
            3748-4751           BC094217.1         1394-2397
FEATURES             Location/Qualifiers
     source          1..4751
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 27.87 cM"
     gene            1..4751
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /note="apoptotic chromatin condensation inducer 1"
                     /db_xref="GeneID:56215"
                     /db_xref="MGI:MGI:1891824"
     exon            1..463
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..4168
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /note="isoform 2 is encoded by transcript variant 2;
                     apoptotic chromatin condensation inducer in the nucleus"
                     /codon_start=1
                     /product="apoptotic chromatin condensation inducer in the
                     nucleus isoform 2"
                     /protein_id="NP_075679.2"
                     /db_xref="CCDS:CCDS27097.1"
                     /db_xref="GeneID:56215"
                     /db_xref="MGI:MGI:1891824"
                     /translation="MWGRKRPNSSGETRGILSGNRGVDYGSGRGQSGPFEGRWRKLPK
                     MPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRL
                     KGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAA
                     ELEEASAESEDEMTHPEGVASLLPPDFQSSLNRPELELSTHSPRKSSSFSEEKGESDD
                     EKPRKGERRSSRVRQAKSKLPEYSQTAEEEEDQETPSRNLRVRADRNLKIEEEEEEEE
                     EEEDDDDEEEEEVDEAQKSREAEAPTLKQFEDEEGEERTRAKPEKVVDEKPLNIRSQE
                     KGELEKGGRVTRSQEEARRSHLARQQQEKETQIVSLPQEENEVKSSQSLEEKSQSPSP
                     PPLPEDLEKAPVVLQPEQIVSEEETPPPLLTKEASSPPTHIQLQEEMEPVEGPAPPVL
                     IQLSPPNTDAGAREPLASPHPAQLLRSLSPLSGTTDTKAESPAGRVSDESVLPLAQKS
                     SLPECSTQKGVESEREKSAPLPLTVEEFAPAKGITEEPMKKQSLEQKEGRRASHALFP
                     EHSGKQSADSSSSRSSSPSSSSSPSRSPSPDSVASRPQSSPGSKQRDGAQARVHANPH
                     ERPKMGSRSTSESRSRSRSRSRSASSSSRKSLSPGVSRDSNTSYTETKDPSCGQEAAA
                     PSGPQLQVLEPKEKAPTFSASVRGRHLSHPEPEQQHVIQRLQPEQGSPKKCEAEEAEP
                     PAATQPQTSETQISHLLESERTHHTVEEKEEVTMDTSENRPENEVPEPPLPVADQVSN
                     DERPEGGAEEEEKKESSMPKSFKRKISVVSATKGVQAGNSDTEGGQPGRKRRWGASTA
                     ATQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKG
                     LKICRTVTQVVPAEGQENGQREEEEEKEPEAELPAPPQVSVEVALPPPVEHEVKKVTL
                     GDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKEL
                     LGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQ
                     DELDYHRGLLVDRPSETKAEEQGAPRPLHPPPPPPVQPPPHPRAEQREQERAVREQWA
                     EREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEE
                     PPAKLLDDLFRKTKAAPCIYWLPLTESQIVQKEAEQAERAKEREKRRKEREEEEQKER
                     EKEAERERNRQLEREKRREHSRERERDRERERDRGDRERERERDRDRGRERDRRDTKR
                     HSRSRSRSTPVRDRGGRR"
     exon            464..529
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            530..641
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            642..761
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            762..850
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            851..2113
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2332
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2333..2448
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2449..2590
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2591..2633
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2767
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2920
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            2921..3059
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            3060..3205
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3313
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            3314..3421
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..3746
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            3747..3847
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     exon            3848..4735
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4706..4711
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /note="hexamer: AATAAA"
     polyA_site      4735
                     /gene="Acin1"
                     /gene_synonym="2610036I19Rik; 2610510L13Rik; Acinus;
                     acinusL; acinusS; Acn; mKIAA0670"
                     /note="major polyA site"
ORIGIN      
        1 atagccgaat atctccgatt atgggtatgc cagattcgag ggcttccgaa gagattcgat
       61 tcaaagcccc ggcaagccga aaacaaacga gcctgaaagc cagatgggag gggccagccg
      121 ctaggtagat ggaaaaagcc gattggtacc gatgtgggga cggaaacgac cgaacagctc
      181 cggagaaacc cggggaattc tgagcggtaa tagaggggta gactatggca gtgggcgggg
      241 ccaatccggt ccgttcgaag ggcgttggcg gaaattaccg aagatgcccg aagccgtcgg
      301 gacggacccg agtacctcac gcaagatggc ggagctggag gaggtgactc tggacgggaa
      361 gcctcttcag gctctgcggg tgaccgacct gaaggccgca ctggagcagc gaggcctagc
      421 caagagcggg cagaagagtg ccctggtcaa gcggctcaaa ggggctctaa tgctagaaaa
      481 tttacaaaaa cactcaacac cccatgctgc attccagcca aattcacaga tcggggagga
      541 aatgagccag aacagcttca taaagcagta tctggaaaag cagcaggagc tacttaggca
      601 gcgcctggaa cgggaagctc gggaggctgc ggaacttgaa gaagcctcag ctgagtcgga
      661 ggacgagatg acccatcctg agggagtggc ttccctgctg cctcctgatt ttcagagcag
      721 cctgaacaga ccagagctgg agctcagcac acattcaccc cgaaagagct cctctttttc
      781 tgaagaaaaa ggagaatctg atgatgagaa gccgaggaaa ggggaaagac gatcatccag
      841 agttagacag gcaaaatcta aactccctga gtacagtcag actgctgagg aggaagagga
      901 tcaagagaca ccatctagaa acctgagggt cagagcagat cgaaatttaa aaatagagga
      961 ggaggaagaa gaagaggaag aagaagaaga tgacgatgat gaagaggaag aggaggtaga
     1021 tgaggcacag aaatctagag aggctgaggc accaaccctg aagcagtttg aggatgaaga
     1081 aggggaagag aggaccagag caaaaccaga aaaggtggtg gatgagaaac ccctaaacat
     1141 cagatcccag gaaaagggtg agttagagaa aggagggcga gttactagat cccaagaaga
     1201 agctagaaga agtcatctgg ccagacagca acaagagaaa gagacacaaa ttgtttctct
     1261 ccctcaagaa gaaaatgagg taaagtcttc acaaagtttg gaggaaaaat cccagtctcc
     1321 ctccccacct ccgcttcctg aagacctaga gaaggcccct gttgtgctgc agccagaaca
     1381 gatagtcagt gaagaggaaa cacccccacc tttacttacc aaggaagcgt catctccacc
     1441 aactcatata caactccagg aagagatgga gccagtggaa ggcccagcac cccctgtcct
     1501 cattcagttg tctcctccta acacagatgc tggagccagg gagccactag cgtctcctca
     1561 ccctgcgcag ctgctaagaa gcctgtctcc tttgtcaggt actacagaca ccaaagcaga
     1621 gtctccagca gggagagtgt cagatgagag tgtcctgcct ctggctcaga aaagctcact
     1681 gcctgaatgc tccacccaga agggtgttga aagtgagcgt gaaaagtctg ctcccctccc
     1741 tctaacagtg gaggagttcg cacctgccaa aggcatcact gaggaaccta tgaagaaaca
     1801 gtctttggaa cagaaggagg gcagaagagc ctcccatgct ctcttcccag agcacagtgg
     1861 gaagcagtca gccgactcat cctctagcag gtcctcctcc ccttcatcct ccagctctcc
     1921 atccagatct ccatctcctg acagtgtggc ttcccgccca cagtcgtctc caggatctaa
     1981 gcagagagat ggagcccaag cacgagttca tgccaaccct cacgagagac ccaagatggg
     2041 ctccaggtca acttcagagt ccaggtcacg ttcccgatct cgttcccgtt ccgcgtcaag
     2101 cagcagcaga aaatctctga gccctggagt ctccagagat agcaacacca gctacactga
     2161 aaccaaagat ccctcttgtg gtcaggaggc tgcagctcca tctgggccac agctgcaggt
     2221 ccttgaacca aaggagaagg ctcccacgtt ctcagcatct gtccggggga ggcatctgag
     2281 ccatcctgag ccagagcaac agcacgtgat ccagaggttg cagccggagc aggggagccc
     2341 aaagaagtgt gaagctgaag aggcagagcc accagctgcc acacagcctc aaacctcaga
     2401 gactcagatc tctcatctgc tagaatcaga aaggactcat cacactgttg aagagaagga
     2461 ggaagtgacc atggacacca gtgaaaacag acctgaaaat gaggtgcctg agcctcctct
     2521 gcctgttgca gaccaagtca gcaatgatga gcgcccagag ggtggtgctg aagaagagga
     2581 aaagaaagag agttcgatgc ccaagtcatt caagaggaaa atctccgttg tctcagctac
     2641 caagggggtg caagctggaa acagtgacac agaggggggc cagcctggcc gaaaacgccg
     2701 ttggggagcc agcactgccg cgacacagaa gaaaccgtcc atcagtatca ccactgagtc
     2761 actcaagagc ctcatccccg acatcaaacc cctggcgggg caggaggctg ttgtggatct
     2821 tcatgccgat gactcccgaa tctctgagga tgagacagag cgtaatggcg acgatgggac
     2881 ccatgacaag ggactgaaga tatgccggac agtcactcag gtagtacccg cagagggcca
     2941 ggagaatggg cagagggaag aggaagaaga gaaagagcct gaagccgagc tgccggcgcc
     3001 accccaggtg tcagtggagg ttgccttgcc cccacctgtg gagcacgaag taaagaaagt
     3061 aacattagga gataccttaa cccggaggtc catcagccaa cagaagtctg gagtttccat
     3121 tacaattgat gacccagtcc ggaccgccca ggtgccctcc ccacccaggg gcaagatcag
     3181 taacattgtc cacatctcca acctggttcg tcccttcact ttaggccagc tgaaggaatt
     3241 attggggcgt acaggaactt tggtggaaga ggccttctgg atagacaaga tcaaatctca
     3301 ttgctttgtg acgtactcta cagtagagga agccgttgcc acccgcacag ctctgcacgg
     3361 ggtcaagtgg ccccagtcca accccaaatt cctttgtgct gactatgctg agcaagatga
     3421 gctggactat caccggggac tcttggtaga tcggccatct gaaactaagg cagaggaaca
     3481 gggagcacca aggcccctgc atcccccacc cccaccccca gtccagccac cgccccaccc
     3541 ccgggctgag cagcgggagc aggaaagggc tgttcgagag caatgggcag aacgggaacg
     3601 ggaaatggag cgccgggaga ggactcggtc tgagagagaa tgggatcggg acaaagttcg
     3661 agagggaccc cgctcccgat cacggtcccg tgaccgccgc cggaaagagc gagcaaaatc
     3721 taaagaaaag aagagtgaaa agaaagaaaa agcccaggag gagccacctg ccaagctgct
     3781 ggatgacctc ttccgtaaga ctaaggcagc tccctgcatc tattggctcc ctctgactga
     3841 gagccaaatt gttcagaagg aggcagagca agctgaacgg gccaaggagc gggagaagcg
     3901 gcgaaaagaa cgagaagaag aagaacaaaa ggaacgggag aaggaagctg agcgggaacg
     3961 gaaccggcag ctagaacggg agaagaggag ggagcacagc agggagagag agagggacag
     4021 ggagagagag cgggacaggg gtgaccgaga gcgggagagg gagcgagacc gagaccgagg
     4081 cagggagagg gatcgcagag acaccaagcg ccacagcaga agccggagtc gaagcacacc
     4141 tgtacgggac cggggtgggc gccgctagcc aagaaaacac tagagagctg caggtacctg
     4201 ccacttggtc ctgggaggtc aaaggccaca gagggatagg tacagtcacc accaccctgg
     4261 aaccaagggt ctcacaccat tgctcagtgc tgaactataa ctgccacacg tcccctcata
     4321 tcaaatggag cagtggcaat ctccctgttc cccaacctaa ctcttggaac ttggccctct
     4381 cctttcttcc tgttaagtct gagagggaag agctaggcta tgaagggaag atgtggccgt
     4441 acgtgggaat aaccagtgtc ccacgctcat tttccctcca tcctgcgttc cgcctccctt
     4501 ggtactcagc cttttgggga cagctggggc caggactggg tcacctatga gctgaatcag
     4561 cctctcctga gtcccaggcc cctgcagtcc cctgttctct ggcctgcagt ctcttgcccg
     4621 ctggttccac tttatagcca ccttttcctt ttgttcaatt tttattttta ttttttttat
     4681 tattaaatga tgtggtctat ggaaaaataa aaatctgact tagttttgac tagcaaaaaa
     4741 aaaaaaaaaa a
//
