LOCUS       NM_001033452            2225 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus 1-aminocyclopropane-1-carboxylate synthase
            (inactive)-like (Accsl), transcript variant 1, mRNA.
ACCESSION   NM_001033452
VERSION     NM_001033452.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2225)
  AUTHORS   Yu,C., Ji,S.Y., Dang,Y.J., Sha,Q.Q., Yuan,Y.F., Zhou,J.J.,
            Yan,L.Y., Qiao,J., Tang,F. and Fan,H.Y.
  TITLE     Oocyte-expressed yes-associated protein is a key activator of the
            early zygotic genome in mouse
  JOURNAL   Cell Res 26 (3), 275-287 (2016)
   PUBMED   26902285
REFERENCE   3  (bases 1 to 2225)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 2225)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   5  (bases 1 to 2225)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF913709.1, AK135828.1 and BM225295.2.
            
            On Oct 24, 2012 this sequence version replaced NM_001033452.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK135828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                CF913709.1         1-54
            55-2222             AK135828.1         2-2169
            2223-2225           BM225295.2         1-3                 c
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 51.62 cM"
     gene            1..2225
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /note="1-aminocyclopropane-1-carboxylate synthase
                     (inactive)-like"
                     /db_xref="GeneID:381411"
                     /db_xref="MGI:MGI:3584519"
     exon            1..136
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..1857
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /note="isoform 1 is encoded by transcript variant 1; novel
                     aminotransferase class I and II domain containing protein;
                     1-aminocyclopropane-1-carboxylate synthase
                     (non-functional)-like; 1-aminocyclopropane-1-carboxylate
                     synthase-like protein 2; ACC synthase-like protein 2;
                     1-aminocyclopropane-1-carboxylate synthase
                     homolog(non-functional)-like; probable inactive
                     1-aminocyclopropane-1-carboxylate synthase-like protein 2"
                     /codon_start=1
                     /product="probable inactive
                     1-aminocyclopropane-1-carboxylate synthase-like protein 2
                     isoform 1"
                     /protein_id="NP_001028624.2"
                     /db_xref="CCDS:CCDS38183.1"
                     /db_xref="GeneID:381411"
                     /db_xref="MGI:MGI:3584519"
                     /translation="MSENRNEGSSQAAKANSDTQTPSHFKVTHPRLRDQLKKKSSKKK
                     GFKFVQEKMLKFQHVIRNQFLQQISQQMQCVPPGDQQCTQTSRKRKKMGYLLSQMVNF
                     LWSNTVKKLKFKVPLPCLDSRCGIKVGHQTLSPWQTGQSRPSLGGFEAALASCTLSKR
                     GAGIYESYHLSFQSYEAYQADKYHKDKNPSGYINLSTSENKLCLDLITARLTQSDMNL
                     LDEAQLQYSDWKGQPFLREELASFLTHYCKAPTPLDPENVVVLNGCSSVFASLAMVLC
                     DPGDALLIPTPCYNGFVFSSHLYSKIELIPVHLESQVPRSNLDSFQLTVDKLKLALTQ
                     AKKKAKKVKGLVLINPQNPLGDVYTQSSLQEYLVFAKTHKLHVIMDEIYMLSVFEPSV
                     TFHSVLSIKDLPDPNMTHMIWGTSKDFGMSGIRFGVLYTHNKEVASAMKAFGYHHGVS
                     GITQYKLCRLLQDKEWISKVYLPKNHSRLQKAYSYITKILKDLKIPFYNGGSGLFVWI
                     NLKAYLSPCTFDQEQILHQRFRDKKLLLSSGKSYMCIEPGWFRLVFAETHLHLQVAMD
                     RFCHVLAEHKKHEK"
     exon            137..684
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            685..744
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            745..815
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            816..885
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            886..952
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1050
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1128
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1229
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1319
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1365
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1507
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1650
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1804
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     exon            1805..2225
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2197..2202
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /note="hexamer: AATAAA"
     polyA_site      2223
                     /gene="Accsl"
                     /gene_synonym="Gm1967"
                     /note="major polyA site"
ORIGIN      
        1 cattaccctg caagccacct tgtgcttaaa agagagggga gggggcggag gagcaagctt
       61 ctgctccctg aatgacaaag acactcctgg atttagactt cggactgcac agagatgagt
      121 gagaacagaa atgaaggctc cagccaggct gccaaggcta atagtgatac ccagactcca
      181 agtcacttca aagtcaccca ccccagactc agggatcagc tgaagaagaa gtcctccaaa
      241 aagaagggct tcaaatttgt gcaggagaag atgttgaagt ttcagcatgt catcaggaat
      301 cagttcttgc agcagataag ccagcagatg cagtgcgtcc cgccgggaga tcagcaatgc
      361 acacaaacct ccaggaagcg gaaaaagatg ggctacctac tgtctcagat ggtcaacttc
      421 ttatggtcta acactgtaaa gaaactgaag ttcaaagtac ctctcccttg cttggactct
      481 agatgtggca tcaaagttgg gcaccagacc ctgtcacctt ggcagactgg ccaatccagg
      541 cctagtctgg gtggctttga ggctgccctt gccagctgca ccctatctaa gcgtggggct
      601 ggcatctatg agtcttacca cttaagcttc cagagctacg aggcctatca ggctgacaaa
      661 taccacaagg ataagaaccc ttcgggctac atcaacctta gtaccagcga gaacaagctt
      721 tgccttgacc tgataacagc gaggttgact cagagtgaca tgaacttact tgatgaggcc
      781 cagctgcagt actccgactg gaaaggacaa cccttccttc gggaagagct ggctagcttc
      841 ttgacccact actgcaaggc gcctacaccc cttgacccag aaaatgtggt ggttctaaat
      901 ggctgctcct cagtctttgc ttcactggcc atggttctgt gtgacccagg tgatgccctt
      961 ctgatcccca caccgtgcta caatggcttt gtcttcagct cccacctcta ttccaaaatc
     1021 gagcttattc ctgtccactt ggagagccag gtccccagat ccaacttgga ttctttccaa
     1081 ctcactgtgg ataagctcaa gcttgccctg actcaggcta agaagaaggc aaaaaaggtc
     1141 aaaggccttg tgctcatcaa cccccagaat cctctgggtg atgtctacac tcagtcgtca
     1201 ctgcaagaat acctggtctt tgctaagact cacaagctgc acgtgatcat ggacgagatt
     1261 tacatgctgt cagtgtttga gccgtctgtc acatttcaca gcgttctgag cataaaagac
     1321 ttgcctgacc ctaacatgac ccatatgatc tggggcacta gtaaggattt cggcatgtct
     1381 ggcatccgct ttggtgttct ctatacacac aacaaggagg tagcctctgc catgaaagct
     1441 tttggctacc accatggggt ctctggcatt actcagtaca agctgtgccg actgctccag
     1501 gacaaagagt ggatcagtaa ggtgtacctt cctaaaaacc atagccggct ccagaaggct
     1561 tacagctata tcactaagat cctgaaggac ttgaagatcc ccttttacaa cggtggctct
     1621 ggcctctttg tctggatcaa cttgaaagct tatctgagtc catgcacatt tgaccaagag
     1681 cagatccttc accagcgctt ccgggacaag aagctgttat tatctagtgg caaatcctac
     1741 atgtgtatag agcctggctg gttccgactc gtctttgcag aaacccacct tcacctacaa
     1801 gtggccatgg atcggttctg ccacgtgctt gctgaacaca aaaagcatga aaagtaaaca
     1861 gcaggagcag gcagccagga catagactgc tgcccccacc cagtggctcc agagagcctg
     1921 ctgtcacttg ctcaggggcc cctgaaagta acctcgtggc caggagacag gaggaggaat
     1981 tggagtcacc gtgctgtctg acctcactca tcgagtcccc tacgctgagt gtctgacatt
     2041 tttagaagcc ttgtttcttt tagtcttcgc tagccagact gtgctcaaaa tgatgttttt
     2101 attgtagtag gagggagaag gcctaaggaa ccctggagag gtaaaggctg ttccccggat
     2161 tcctttttag atggctttgt tttgcattca ccatttaata aaagtcatgc tctattttct
     2221 ccagc
//
