LOCUS       NM_001102437            3746 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus acyl-Coenzyme A binding domain containing 5 (Acbd5),
            transcript variant 1, mRNA.
ACCESSION   NM_001102437
VERSION     NM_001102437.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3746)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3746)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3746)
  AUTHORS   Darwisch,W., von Spangenberg,M., Lehmann,J., Singin,O., Deubert,G.,
            Kuhl,S., Roos,J., Horstmann,H., Korber,C., Hoppe,S., Zheng,H.,
            Kuner,T., Pras-Raves,M.L., van Kampen,A.H.C., Waterham,H.R.,
            Schwarz,K.V., Okun,J.G., Schultz,C., Vaz,F.M. and Islinger,M.
  TITLE     Cerebellar and hepatic alterations in ACBD5-deficient mice are
            associated with unexpected, distinct alterations in cellular lipid
            homeostasis
  JOURNAL   Commun Biol 3 (1), 713 (2020)
   PUBMED   33244184
  REMARK    GeneRIF: Cerebellar and hepatic alterations in ACBD5-deficient mice
            are associated with unexpected, distinct alterations in cellular
            lipid homeostasis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3746)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3746)
  AUTHORS   Ye,A., Kim,H. and Kim,J.
  TITLE     PEG3 control on the mammalian MSL complex
  JOURNAL   PLoS One 12 (6), e0178363 (2017)
   PUBMED   28609438
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3746)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY126800.1, AK147839.1, AK005001.2 and BC090641.1.
            
            Transcript Variant: This variant (1) lacks an alternate in-frame
            exon compared to variant 5. The resulting isoform (a) has the same
            N- and C-termini but is shorter compared to isoform e.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147839.1, SRR1660819.161771.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 BY126800.1         6-9
            5-653               AK147839.1         5-653
            654-2704            AK005001.2         443-2493
            2705-3746           BC090641.1         2530-3571
FEATURES             Location/Qualifiers
     source          1..3746
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 15.21 cM"
     gene            1..3746
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="acyl-Coenzyme A binding domain containing 5"
                     /db_xref="GeneID:74159"
                     /db_xref="MGI:MGI:1921409"
     exon            1..213
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..1728
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     acyl-CoA-binding domain-containing protein 5"
                     /codon_start=1
                     /product="acyl-CoA-binding domain-containing protein 5
                     isoform a"
                     /protein_id="NP_001095907.1"
                     /db_xref="CCDS:CCDS57156.1"
                     /db_xref="GeneID:74159"
                     /db_xref="MGI:MGI:1921409"
                     /translation="MLFLAFHAGSWGSWCCCCCVITADRPWDRGRRWQLEMADTPSVY
                     ETRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATEGPCKLSRPGFWDPIGRYKW
                     DAWSSLGDMTKEEAMIAYVEEMKKIIETMPMTEKVEELLHVIGPFYEIVEDKKSSKSS
                     DLTSDLGNVLTSSNAKAVNGKAESSDSGAESEEEEAQEELKGAEQSGSDDKKTLKKSA
                     DKNLEIIVTNGYKGSFVQDIQSDIHTDSSRSTRSSEDEKPGDESSQQTGHTIVCAHQD
                     RNEDPSEDASGIHHLTSDSDSEVYCDSMEQFGQEEYYLGGDPTQHLESSGFCEDAQQS
                     PGNGSIGKMWMVAVKGKGEVKHGGEDGRSSSGAPHRETRGGESEDFSSVRRGRVGNRI
                     PHLSEGPKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLIRLQEDMQNVLQRLHKLET
                     LTASQAKLSLQTSNQPSSQRPAWWPFEMSPGALAFAIIWPFIAQWLAHLYYQRRRRKL
                     N"
     exon            214..382
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            383..503
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            504..576
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            577..691
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            692..826
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            827..1024
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1131
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1360
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1563
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1605
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1715
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..3724
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2511..2516
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="hexamer: AATAAA"
     regulatory      2516..2521
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="hexamer: AATGAA"
     polyA_site      2527
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="major polyA site"
     polyA_site      2551
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="major polyA site"
     regulatory      3611..3616
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3641
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
     polyA_site      3688
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
     regulatory      3700..3705
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3724
                     /gene="Acbd5"
                     /gene_synonym="1300014E15Rik"
ORIGIN      
        1 ggggtttgct gcacggcggc cgcggcggcg gaggctagtg ggtcctccgg tgactctggg
       61 gcggggctgt ggggcggctg cccaccgacg gcagaacttc tcaggaatgg ggggtgtgat
      121 tggttggccg gcatcttccg ggtgggagaa agggtccgct atcacgggcg gctcaacctc
      181 caaggcctgc tgctagagat gctcttcctc gcgtttcatg caggctcttg gggaagctgg
      241 tgctgctgct gctgtgtgat taccgcggac agaccttggg accgaggccg gcgctggcag
      301 ctggagatgg cggacacacc gtcagtgtat gaaaccagat ttgaggcggc cgtgaaggtg
      361 atccagagtt tgccgaaaaa tggatcattc caaccaacaa atgaaatgat gcttaagttc
      421 tatagcttct acaaacaggc aactgaagga ccctgtaaac tttcacggcc tggattctgg
      481 gatcctattg gaagatataa atgggatgct tggagttcac tgggtgatat gactaaagaa
      541 gaagccatga ttgcatatgt tgaagaaatg aaaaagatta ttgaaaccat gcccatgact
      601 gagaaagtgg aagagttgct gcatgttata ggtccatttt acgagattgt agaagacaaa
      661 aagagcagca agagttctga cttgacctca gatcttggta atgttctgac ctcttcaaat
      721 gccaaagctg ttaatggtaa agcagagagc agtgatagtg gggctgagtc tgaagaagaa
      781 gaggcccaag aagagttaaa aggagcagaa cagagcggca gtgatgataa gaaaacgctg
      841 aagaaatcag cagataagaa tttggaaatc attgttacca atggctataa aggtagcttt
      901 gttcaggata tacagagtga cattcatact gattcttccc ggagcaccag aagcagtgaa
      961 gatgaaaagc ctggagatga gagctctcag cagacaggac acaccattgt ctgtgctcac
     1021 caagatagaa atgaagatcc cagtgaagat gcttcaggaa tacaccattt aacaagtgat
     1081 tcagatagtg aagtgtactg tgactctatg gagcaatttg gacaagaaga gtattattta
     1141 ggtggtgatc ctactcagca cttggaaagt tctggttttt gtgaagatgc tcagcaatct
     1201 cctggaaatg gcagcattgg gaaaatgtgg atggtagcag tcaaaggaaa aggcgaagtg
     1261 aaacacggag gagaagatgg cagaagtagc agtggagcac cgcaccgtga gacgagaggt
     1321 ggagagagcg aggacttctc cagtgtcagg agagggagag tagggaatag aataccacat
     1381 ttgagcgaag gacccaaggg tcggcaagta ggaagtggag gtgatggaga acgctggggc
     1441 tcagaccggg ggtccagagg cagcctcaat gagcagatcg ctcttgtgct cattagattg
     1501 caggaggaca tgcagaatgt ccttcagaga cttcataaac tggaaacact aactgcttcg
     1561 caggcgaaat tatctttgca gacaagtaat cagccctcct cacagagacc agcttggtgg
     1621 ccctttgaga tgtcccctgg tgcattagct tttgctatta tatggccttt tattgctcag
     1681 tggttggcac atttgtatta tcaaagaagg agaagaaaac taaattgaag aaatggcttt
     1741 ttactcaaga agactgctgg gcctggacga cctaagagac ggactggaaa tgaagtggaa
     1801 ttcagaagaa aatctcagtt ttgatgatta cgttgctttt ttgtccagta gtttggttta
     1861 tatacataaa tattctttgc actacacaaa tggtaacatt ttaaagacta atattgctga
     1921 tacttgaaaa atcaatctca actagatttt aagtagcatc catagactta ctctttttga
     1981 gcttgaagga ctaaattatt aattattgtt cagtaatgat cacctaattt ttcccataag
     2041 aattataagc tgcatttcta aggcatagct ccaattatga gataaaattt atacttttta
     2101 cttttctaaa ttaaacacaa gaaagaatgc aaaaacaaaa gtgatttttt aaaaatgagg
     2161 ttaaatcgat tttgcatcag tcactgaact gtcagctacg tggcaggaac cggacggaag
     2221 aatcctctcc aggagactgg gctttagtta gtggcttgat tccccggctt gctcaaggga
     2281 actcagaaaa tcatcgtcct tgtactgcgc ttctgtttac aaacgattca ctgaacagac
     2341 ttaacttgat gatggaaatg atgaaaaaca ggcctaatgt aggtgtaaaa gtgtattcaa
     2401 actctagaca cggctaatca gattttaatt caatcataca cacataatcc tttgtaatca
     2461 tttttctttt aagtgaggat atctactgtc tgcttcatag ggtgctttgc aataaaatga
     2521 aaacgtattt atactgtttt tactaaggta acaaaagcat gataatcctt ttttttgcaa
     2581 gtgtaaacga cagtctggac tcttaacttc ttagtgcctc agttttcctt tggggtatac
     2641 ttcacaaggt atcagaagta ctttcagtct acaggtctct atgtccacat aactaaggaa
     2701 tgcctaacta atggaaactt aagttccttc tagccattaa aacagagaga agatcaattt
     2761 agatcccgga acactgtatt tgaaaaataa tcttcctgtg tactttctca aacctgcgct
     2821 cagtaatata ctttattctt tgaagattta atttaaaaac ttcatagaaa atcctttttt
     2881 gcttttcctt ttgagacaga gttttggtag ctcctaccag cctccaattc tctatgtagc
     2941 tgaagatgac cttgactacc tgagtttcct gtctctactt cttttcagct tctgggacca
     3001 caggcctgta ccaccatggc cagctttaga gagtaaaaca ttttaatttg ttcttgattt
     3061 gtatgatgtt gggggcgtta gcattacgtg ttgaatattt tgagtaagaa gaaaagaatc
     3121 catcttcaga atatagggtt gttctttggg aaaaagagta taagaacata atttctttgt
     3181 cctagacttt acaaattttt caaaactgta actttatttt aaacttgtgt atcacaactt
     3241 ggttgatatg cctaaaatga tctactggct tttgcttatg attaaaaaac ctcaaatcta
     3301 tcttctacat tttaaaagga agaaaaaaaa gcaaataact gaattattat agaaaacttt
     3361 agacctgtga catttttttg ttttaaatta caaaagaggt tggtatgata aagtgatggc
     3421 ttttttctta tataaataga atgcaaatca aagatataac cagtgtgatt gattgcaagt
     3481 agtcaagtgt aactaactcc taagggcaac catttgtatc ttatatatca gaattacttt
     3541 atagtttgaa agcactttgc acacatttcc tgtatataaa ggatgtaatt acaggatata
     3601 gtggtaatgc attaaaacat gaacctcatt ttagaaatcg acagctatgg tattttttta
     3661 atgatcagct tttctgttta ttgtaaaact aagttaaaaa ataaaaggtt aatgagaaat
     3721 gaaaaaaaaa aaaaaaaaaa aaaaaa
//
