LOCUS       NM_175324               3354 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus acyl-Coenzyme A dehydrogenase family, member 11
            (Acad11), mRNA.
ACCESSION   NM_175324
VERSION     NM_175324.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3354)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3354)
  AUTHORS   El-Saafin,F., Bergamasco,M.I., Chen,Y., May,R.E., Esakky,P.,
            Hediyeh-Zadeh,S., Dixon,M., Wilcox,S., Davis,M.J., Strasser,A.,
            Smyth,G.K., Thomas,T. and Voss,A.K.
  TITLE     Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic
            neuronal cell death
  JOURNAL   Cell Death Differ 29 (5), 1013-1027 (2022)
   PUBMED   35361962
REFERENCE   3  (bases 1 to 3354)
  AUTHORS   Mulligan,M.K., Ponomarev,I., Hitzemann,R.J., Belknap,J.K.,
            Tabakoff,B., Harris,R.A., Crabbe,J.C., Blednov,Y.A., Grahame,N.J.,
            Phillips,T.J., Finn,D.A., Hoffman,P.L., Iyer,V.R., Koob,G.F. and
            Bergeson,S.E.
  TITLE     Toward understanding the genetics of alcohol drinking through
            transcriptome meta-analysis
  JOURNAL   Proc Natl Acad Sci U S A 103 (16), 6368-6373 (2006)
   PUBMED   16618939
REFERENCE   4  (bases 1 to 3354)
  AUTHORS   Olbrich,H., Fliegauf,M., Hoefele,J., Kispert,A., Otto,E., Volz,A.,
            Wolf,M.T., Sasmaz,G., Trauer,U., Reinhardt,R., Sudbrak,R.,
            Antignac,C., Gretz,N., Walz,G., Schermer,B., Benzing,T.,
            Hildebrandt,F. and Omran,H.
  TITLE     Mutations in a novel gene, NPHP3, cause adolescent
            nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis
  JOURNAL   Nat Genet 34 (4), 455-459 (2003)
   PUBMED   12872122
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077531.1 and AI843434.1.
            
            On Jun 20, 2018 this sequence version replaced NM_175324.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK128998.1, BC045199.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3327              AK077531.1         23-3349
            3328-3354           AI843434.1         1-27                c
FEATURES             Location/Qualifiers
     source          1..3354
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 56.25 cM"
     gene            1..3354
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /note="acyl-Coenzyme A dehydrogenase family, member 11"
                     /db_xref="GeneID:102632"
                     /db_xref="MGI:MGI:2143169"
     exon            1..180
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..2377
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /codon_start=1
                     /product="acyl-CoA dehydrogenase family member 11"
                     /protein_id="NP_780533.2"
                     /db_xref="CCDS:CCDS23458.1"
                     /db_xref="GeneID:102632"
                     /db_xref="MGI:MGI:2143169"
                     /translation="METDVTSDTVEVLPQHKFDLRSLEAYLNQHLPGFGSDSRAVLTV
                     TQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKIQKALFSIGFPVAKP
                     LLYCRDASVIGTEFYVMEHVQGRIFRDFSIPGVSSAERAAIYVSVAETLAWLHSLDIR
                     SLKLDKYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMKNLPDSDSEECLVH
                     GDFKLDNIVFHPKECRVIAVLDWELSTFGHPLTDLAHLSLFYYWPRTLPMINRGSHIP
                     ENTGIPLMEELISIYCHRRGIDPNLPNWNFFMALSFFKLAGISQGVYRRYLMGNNSSE
                     DSFLTANTVQPLAETGLQLSKRTLRTTPPQADAKSQLFAQSRRGQEVLTRVKQFMKQH
                     VFPAEKEVAEYYAQSGNSAEKWGHPLVIEKLKEIAKAEGLWNLFLPAVSGLSQVDYAL
                     IAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKKQWLEPLLRGDITSVFCMTEP
                     NVSSSDATNIECTIQRDGGGYIVNGKKWWSSGAGNPKCKIAIVLGRTESPSASRHRQH
                     SMILVPMDTPGVELIRPLSVFGYMDNMHGGHWEVHFNHVRVPASNLILGEGRGFEISQ
                     GRLGPGRIHHCMRTVGLAERILQIMCDRAVQREAFKKKLYEHEVVAHWIAKSRIAIEE
                     IRLLTLKAAHSIDTLGSASARKEIAMIKVAAPKAVCKIADWAIQVHGGAGVSQDYPLA
                     NMYAIIRTLRLADGPDEVHLSAIAKMELQDQARRLTARM"
     exon            181..280
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            281..406
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            407..568
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            569..733
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            734..875
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            876..997
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1104
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1231
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1309
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1448
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1556
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1655
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1656..1722
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1808
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1880
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1881..2035
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2036..2152
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2262
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2263..3337
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3309..3314
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3327
                     /gene="Acad11"
                     /gene_synonym="5730439E10Rik"
                     /note="major polyA site"
ORIGIN      
        1 acagtctgtg gattcctcgg tgacaacagt ggcggtcatg gagacggatg tcaccagtga
       61 caccgtggaa gtgctacccc agcacaagtt cgacctcagg tccctggagg cctacctgaa
      121 tcagcacttg ccgggctttg ggtcagattc ccgggctgtg ctgactgtta ctcaatacag
      181 atcaggacag tcaaacccaa ccttctttct ccagaaagga tctcaagcct atgttctcag
      241 gaagaaacca cccggctctc ttcttcccaa agcacataag attgacagag aattcaagat
      301 ccagaaagcc ttgttttcca ttggatttcc tgttgccaag cccctgctat actgcagaga
      361 tgcttcagtt atcggaacgg aattttatgt aatggaacat gtgcagggtc ggatctttcg
      421 tgatttttcc attcctggag ttagctcagc agaacgtgct gctatatatg tgtctgtggc
      481 agaaaccctg gcatggctac attctctgga tatacgctcg ctgaagctgg acaaatacgg
      541 tactggagtc gggtactgca aaaggcaggt gtccacctgg acgaagcagt accaggcctc
      601 agcccatcag agcatccctg ccatggacca gctctccacg tggctgatga agaacttgcc
      661 agatagtgac agtgaggagt gcctggtcca cggagacttc aagctggaca acatagtttt
      721 ccaccccaaa gagtgtcggg ttatagcagt gttggactgg gagctctcga ccttcggcca
      781 tcccttgacg gacttagccc atctttcctt gttttactat tggcccagga cactgcccat
      841 gataaaccga ggctctcaca ttccagagaa cacaggaata ccgttgatgg aagaactgat
      901 ttcaatatac tgccaccgaa ggggaattga tcctaatctc cctaactgga atttctttat
      961 ggccctctca ttttttaaat tggctggaat atcacaggga gtctatcgta gatacctcat
     1021 gggaaataac tcatctgagg atagcttctt aactgccaat actgtgcaac ctctggcaga
     1081 aactggattg cagctgtcaa aaagaactct caggactaca ccaccacagg ctgatgctaa
     1141 aagccagctg tttgcacaga gcaggagagg ccaggaagtt ctcactagag tgaagcagtt
     1201 catgaagcag catgtctttc ctgctgagaa ggaagtagct gaatactatg ctcaaagtgg
     1261 aaactcagcg gaaaagtggg gacacccctt agtgatcgaa aaactaaagg aaatagccaa
     1321 agcagagggc ctgtggaatt tgttcttgcc agctgtgagc ggtctcagcc aggtggacta
     1381 tgccttgatt gctgaagaga caggaaaatg cttttttgct ccagatgttt ttaactgcca
     1441 agcaccagac acaggcaaca tggaggtact gcacctgtat ggcagcgagc agcagaagaa
     1501 gcagtggctg gagcctctcc tgcgtggcga tatcacctcc gtcttctgta tgacagagcc
     1561 caacgtctca tcaagcgatg ccacgaacat cgaatgcacc atccagagag atggaggtgg
     1621 ctatatagtt aacggcaaga agtggtggag cagcggagct gggaatccca agtgcaaaat
     1681 cgccattgtt ttgggaagaa cggagtctcc ctctgcatcc agacacagac agcacagcat
     1741 gatcctcgtg ccgatggaca cacctggagt ggagttaata aggcctttgt cggtgttcgg
     1801 ctacatggat aatatgcatg gcgggcactg ggaggtccat ttcaatcacg tgcgcgttcc
     1861 tgccagcaac ttaatactag gtgaaggcag gggctttgaa atttcccaag gccgccttgg
     1921 acctggaaga atccaccact gtatgagaac cgtgggtttg gcagaacgca ttctgcagat
     1981 catgtgtgac cgggccgtgc agagggaggc cttcaagaag aagctctacg aacatgaagt
     2041 cgtggctcac tggattgcta agagccgtat agccatcgag gagatccgct tgctgacctt
     2101 gaaagcggct cacagcatag atactctggg cagtgcctca gccaggaagg agattgcaat
     2161 gatcaaagtg gctgccccca aagctgtctg caaaatagct gactgggcca tccaggtgca
     2221 cggaggcgcg ggagtttccc aggattaccc tctggctaac atgtacgcca tcatacgcac
     2281 cctgcgcttg gcagacggcc ctgacgaagt ccacctctca gcgatcgcca agatggagct
     2341 tcaggaccaa gccagacggt tgacagccag gatgtgatgg agcaacccgg ggcacactct
     2401 tgaccagctc aaaacttaca tctcacatct cttgagtagt ttgagcacaa ggctaattat
     2461 tcacccatgg taaagatttt agcatctatt tcgatcactg ggttttataa tgttaagtaa
     2521 ggatcacaca gacgtgaggt aaataggaaa ccccataact gccattgagt ctggtgtcta
     2581 atgggttagc attcacttta tacacatgac ctgtgatgag gtcacactga gaatggtaga
     2641 gctatttctg gaattcagcc aagtgaatag acaccccagg cctaaataac cttgttctga
     2701 aatacttgca gctgtacccc ttttagcagt gttttggagc ttaatttagc acctcagaga
     2761 aagcaatagc ttgaagattt cggagttccc aataagcctc tttctaaccc aacaggaagt
     2821 agttctggtg aaatctcatg caggtgaaag ctcacaagga agtgtagcct gttaggagaa
     2881 caggcgatca aggccactta ggttacatag aaaaagctga ggagatccgt aactaatcgg
     2941 tgctatgtca gagctccaca gctccctggg agctggtctg atcaggcgag acatgttctg
     3001 acagctctgc agtgccactg tgggtcacca cagccctctg catcgaaatg tcaccggcac
     3061 agcagaggac agccgttagc tacagttgga aaggtttgag ttggtggtct gctttatcaa
     3121 gtaaggatgt tttgaaatct cgtcacaaag agaaatattt taaatcaaaa tttggcatcc
     3181 aaataaacac agtaagtgtt tacatactgg attttgaaaa cttaactgaa aataatataa
     3241 aatatctact agataatacc tttacatatt gagcctacat cgaattatat tttggaaata
     3301 ctgtattgaa taaaatatac cccagtcttc tctgtttaaa aaaaaaaaaa aaaa
//
