LOCUS       NM_133360               9175 bp    mRNA    linear   ROD 09-JUL-2024
DEFINITION  Mus musculus acetyl-Coenzyme A carboxylase alpha (Acaca), mRNA.
ACCESSION   NM_133360 XM_006531957 XM_109883
VERSION     NM_133360.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9175)
  AUTHORS   Wang,Y., Yang,Y., Xie,L., An,X. and Zhang,L.
  TITLE     MiR-24-3p enhances the Treg/Th17 balance to improve cerebral
            ischemic injury by suppressing acetyl-CoA carboxylase 1 expression
  JOURNAL   J Neuroimmunol 390, 578344 (2024)
   PUBMED   38640826
  REMARK    GeneRIF: MiR-24-3p enhances the Treg/Th17 balance to improve
            cerebral ischemic injury by suppressing acetyl-CoA carboxylase 1
            expression.
REFERENCE   2  (bases 1 to 9175)
  AUTHORS   Deja,S., Fletcher,J.A., Kim,C.W., Kucejova,B., Fu,X., Mizerska,M.,
            Villegas,M., Pudelko-Malik,N., Browder,N., Inigo-Vollmer,M.,
            Menezes,C.J., Mishra,P., Berglund,E.D., Browning,J.D.,
            Thyfault,J.P., Young,J.D., Horton,J.D. and Burgess,S.C.
  TITLE     Hepatic malonyl-CoA synthesis restrains gluconeogenesis by
            suppressing fat oxidation, pyruvate carboxylation, and amino acid
            availability
  JOURNAL   Cell Metab 36 (5), 1088-1104 (2024)
   PUBMED   38447582
REFERENCE   3  (bases 1 to 9175)
  AUTHORS   Dong,J., Li,M., Peng,R., Zhang,Y., Qiao,Z. and Sun,N.
  TITLE     ACACA reduces lipid accumulation through dual regulation of lipid
            metabolism and mitochondrial function via AMPK- PPARalpha- CPT1A
            axis
  JOURNAL   J Transl Med 22 (1), 196 (2024)
   PUBMED   38395901
  REMARK    GeneRIF: ACACA reduces lipid accumulation through dual regulation
            of lipid metabolism and mitochondrial function via AMPK- PPARalpha-
            CPT1A axis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9175)
  AUTHORS   Munoz-Gallardo,M.D.M., Garcia-Padilla,C., Vicente-Garcia,C.,
            Carvajal,J., Arenega,A. and Franco,D.
  TITLE     miR-195b is required for proper cellular homeostasis in the elderly
  JOURNAL   Sci Rep 14 (1), 810 (2024)
   PUBMED   38191655
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9175)
  AUTHORS   Guo,C.G., Sun,R., Wang,X., Yuan,Y., Xu,Y., Li,S., Sun,X., Wang,J.,
            Hu,X., Guo,T., Chen,X.W., Xiao,R.P. and Zhang,X.
  TITLE     Intestinal SURF4 is essential for apolipoprotein transport and
            lipoprotein secretion
  JOURNAL   Mol Metab 79, 101847 (2024)
   PUBMED   38042368
REFERENCE   6  (bases 1 to 9175)
  AUTHORS   Levert,K.L., Waldrop,G.L. and Stephens,J.M.
  TITLE     A biotin analog inhibits acetyl-CoA carboxylase activity and
            adipogenesis
  JOURNAL   J Biol Chem 277 (19), 16347-16350 (2002)
   PUBMED   11907024
  REMARK    GeneRIF: A biotin analog inhibits acetyl-CoA carboxylase activity
            and adipogenesis
REFERENCE   7  (bases 1 to 9175)
  AUTHORS   Patel,D.D., Knight,B.L., Wiggins,D., Humphreys,S.M. and
            Gibbons,G.F.
  TITLE     Disturbances in the normal regulation of SREBP-sensitive genes in
            PPAR alpha-deficient mice
  JOURNAL   J Lipid Res 42 (3), 328-337 (2001)
   PUBMED   11254743
REFERENCE   8  (bases 1 to 9175)
  AUTHORS   Zhang,S. and Kim,K.H.
  TITLE     Acetyl-CoA carboxylase is essential for nutrient-induced insulin
            secretion
  JOURNAL   Biochem Biophys Res Commun 229 (3), 701-705 (1996)
   PUBMED   8954960
REFERENCE   9  (bases 1 to 9175)
  AUTHORS   Shimano,H., Horton,J.D., Hammer,R.E., Shimomura,I., Brown,M.S. and
            Goldstein,J.L.
  TITLE     Overproduction of cholesterol and fatty acids causes massive liver
            enlargement in transgenic mice expressing truncated SREBP-1a
  JOURNAL   J Clin Invest 98 (7), 1575-1584 (1996)
   PUBMED   8833906
REFERENCE   10 (bases 1 to 9175)
  AUTHORS   Myohanen,S., Wahlfors,J., Alhonen,L. and Janne,J.
  TITLE     Nucleotide sequence of mouse spermidine synthase cDNA
  JOURNAL   DNA Seq 4 (5), 343-346 (1994)
   PUBMED   7803821
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596447.16 and AL596252.11.
            
            On or before Apr 1, 2022 this sequence version replaced
            XM_006531957.5, NM_133360.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AY451393.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN00849375, SAMN00849379 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                AL596447.16        58240-58335
            97-143              AL596447.16        71488-71534
            144-393             AL596447.16        73847-74096
            394-526             AL596447.16        92567-92699
            527-665             AL596447.16        94243-94381
            666-775             AL596447.16        101551-101660
            776-857             AL596447.16        102853-102934
            858-956             AL596447.16        104543-104641
            957-1063            AL596447.16        107329-107435
            1064-1174           AL596447.16        110060-110170
            1175-1384           AL596252.11        182496-182705       c
            1385-1555           AL596252.11        178083-178253       c
            1556-1717           AL596252.11        176163-176324       c
            1718-1881           AL596252.11        175674-175837       c
            1882-2032           AL596252.11        171967-172117       c
            2033-2136           AL596252.11        170196-170299       c
            2137-2218           AL596252.11        164766-164847       c
            2219-2364           AL596252.11        164210-164355       c
            2365-2515           AL596252.11        162058-162208       c
            2516-2650           AL596252.11        160773-160907       c
            2651-2797           AL596252.11        159875-160021       c
            2798-2986           AL596252.11        158947-159135       c
            2987-3087           AL596252.11        158159-158259       c
            3088-3176           AL596252.11        157404-157492       c
            3177-3301           AL596252.11        151090-151214       c
            3302-3415           AL596252.11        144884-144997       c
            3416-3529           AL596252.11        143622-143735       c
            3530-3619           AL596252.11        142576-142665       c
            3620-3738           AL596252.11        141021-141139       c
            3739-3762           AL596252.11        131220-131243       c
            3763-3906           AL596252.11        128497-128640       c
            3907-4003           AL596252.11        127538-127634       c
            4004-4111           AL596252.11        126486-126593       c
            4112-4168           AL596252.11        121407-121463       c
            4169-4213           AL596252.11        121066-121110       c
            4214-4255           AL596252.11        114373-114414       c
            4256-4471           AL596252.11        110049-110264       c
            4472-4627           AL596252.11        108649-108804       c
            4628-4831           AL596252.11        105554-105757       c
            4832-4987           AL596252.11        100850-101005       c
            4988-5134           AL596252.11        98902-99048         c
            5135-5404           AL596252.11        82948-83217         c
            5405-5502           AL596252.11        79507-79604         c
            5503-5623           AL596252.11        75445-75565         c
            5624-5734           AL596252.11        74716-74826         c
            5735-5878           AL596252.11        57724-57867         c
            5879-5999           AL596252.11        57084-57204         c
            6000-6096           AL596252.11        52764-52860         c
            6097-6193           AL596252.11        49934-50030         c
            6194-6329           AL596252.11        48817-48952         c
            6330-6507           AL596252.11        40852-41029         c
            6508-6620           AL596252.11        38987-39099         c
            6621-6775           AL596252.11        29867-30021         c
            6776-6946           AL596252.11        29145-29315         c
            6947-7083           AL596252.11        23336-23472         c
            7084-9175           AL596252.11        19880-21971         c
FEATURES             Location/Qualifiers
     source          1..9175
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 51.29 cM"
     gene            1..9175
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /note="acetyl-Coenzyme A carboxylase alpha"
                     /db_xref="GeneID:107476"
                     /db_xref="MGI:MGI:108451"
     exon            1..96
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            97..143
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            144..393
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..7207
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /EC_number="6.4.1.2"
                     /note="ACC-alpha; acetyl-CoA carboxylase 265"
                     /codon_start=1
                     /product="acetyl-CoA carboxylase 1"
                     /protein_id="NP_579938.2"
                     /db_xref="CCDS:CCDS25185.1"
                     /db_xref="GeneID:107476"
                     /db_xref="MGI:MGI:108451"
                     /translation="MDEPSPLAKTLELNQHSRFIIGSVSEDNSEDEISNLVKLDLEEK
                     EGSLSPASVSSDTLSDLGISGLQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVA
                     SPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPED
                     LKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLP
                     ELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKR
                     ILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFR
                     QVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPA
                     AIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEM
                     VADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGHVIAAR
                     ITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENR
                     EEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAER
                     PDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVL
                     KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNK
                     TCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCI
                     HYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVL
                     DNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVE
                     KSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQ
                     RYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSH
                     AQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASH
                     LPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRM
                     AALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFASN
                     LNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEIMGCFCDSPPQS
                     PTFPESGHTSLYDEDKVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVE
                     HGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAF
                     QLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEA
                     SFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSM
                     VMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRT
                     AQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIK
                     LWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSP
                     EYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLA
                     EEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDI
                     IGKEEGLGAENLRGSGMIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVEN
                     SHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSY
                     MPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGS
                     FSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQV
                     WFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECS
                     QPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDL
                     VKTMRRVDPVYIRLAERLGTPELSPTERKELESKLKEREEFLIPIYHQVAVQFADLHD
                     TPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLR
                     RWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSL
                     VQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST"
     exon            394..526
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            527..665
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            666..775
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            776..857
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            858..956
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1063
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1174
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1384
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            1385..1555
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1717
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1881
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2032
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2136
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2137..2218
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2364
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2515
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2650
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2651..2797
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2798..2986
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            2987..3087
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3088..3176
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3177..3301
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3302..3415
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3416..3529
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3530..3619
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..3738
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3739..3762
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3763..3906
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            3907..4003
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4004..4111
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4112..4168
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4169..4213
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4214..4255
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4256..4471
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4472..4627
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4628..4831
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4832..4987
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            4988..5134
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            5135..5404
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            5405..5502
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            5503..5623
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            5624..5734
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            5735..5878
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            5879..5999
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6000..6096
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6097..6193
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6194..6329
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6330..6507
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6508..6620
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6621..6775
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6776..6946
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            6947..7083
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     exon            7084..9175
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9151..9156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /note="hexamer: AATAAA"
     polyA_site      9175
                     /gene="Acaca"
                     /gene_synonym="A530025K05Rik; Acac; Acc1; Gm738"
                     /note="major polyA site"
ORIGIN      
        1 gtcagccatc gccgagccgc cggcgtcgcc tcccgcccag cacatctcgg cgcagggtct
       61 cagcgaccgt cggtccctgc gtgccgccag cctgagttct ttttggaggc ggatatctgc
      121 tgagacaata agaattataa gagctctgag agcttatttt gaaagaataa tggatgaacc
      181 atctccgttg gccaaaactc tggagctaaa ccagcactcc cgattcataa ttgggtctgt
      241 gtctgaagac aactcagaag atgagatcag taacctggtg aagctggacc tagaagagaa
      301 ggagggctcc ctgtcaccag cctccgtcag ctcagataca ctttctgatt tggggatctc
      361 tggcttacag gatggtttgg cctttcacat gagatccagc atgtctggct tgcacctagt
      421 aaaacaaggt cgagacagaa agaaaataga ctcacaacga gatttcactg tggcttctcc
      481 agcagaattt gttactcgtt ttgggggaaa taaagtaatt gagaaggttc ttatcgccaa
      541 caatggtatt gcagcagtga aatgcatgcg atctatccgt cggtggtctt atgaaatgtt
      601 tcgaaatgaa cgtgcaatcc gatttgttgt catggttaca cctgaagacc ttaaagccaa
      661 tgcagaatac attaagatgg cagaccacta tgttccagtg cctggaggac ccaacaacaa
      721 caattacgca aatgtggagt tgattcttga tattgctaaa aggatacctg tacaagcagt
      781 gtgggctggc tggggtcatg cctctgagaa cccgaaactc ccagaactgc tcttaaaaaa
      841 tggcattgct ttcatgggcc ctccaagcca ggccatgtgg gctttggggg ataagattgc
      901 atcttctatt gtggctcaaa ctgcaggtat cccaactctt ccctggagtg gcagtggtct
      961 tcgagtggat tggcaagaaa atgatttttc gaaacgtatc ttaaatgttc cacaggatct
     1021 gtatgagaaa ggctatgtga aggatgtgga tgatggtctg aaggcagctg aggaagttgg
     1081 ctatccagtg atgatcaagg cctcagaggg aggaggaggg aaagggatca gaaaagttaa
     1141 caatgcagat gacttcccta acctcttcag acaggttcaa gctgaagttc ctggatcacc
     1201 tatatttgta atgagactag caaaacaatc tcgacatctg gaggtccaga ttctggcaga
     1261 tcagtatggc aatgctattt ctttgtttgg tcgtgactgc tctgtgcagc gcaggcatca
     1321 gaagatcatt gaagaagctc ctgctgcgat tgctacccca gcagtatttg aacacatgga
     1381 acagtgtgca gtgaaacttg ccaaaatggt tggttatgtg agtgctggga ctgtggaata
     1441 cttgtacagc caggatggaa gcttctactt tttggaactg aaccctcggc tacaggttga
     1501 acatccttgt acagagatgg tggctgatgt caatcttcct gcagcacagc tccagattgc
     1561 catggggatc cctctattta ggatcaagga tattcgtatg atgtatgggg tatctccttg
     1621 gggagatgct cccattgatt ttgaaaattc tgctcatgtt ccttgcccaa ggggccacgt
     1681 gattgctgct cggatcacca gtgaaaaccc agatgagggg tttaagccca gctctggaac
     1741 agttcaggaa cttaattttc gtagcaataa gaacgtttgg ggttatttca gtgttgctgc
     1801 tgctggagga cttcatgaat ttgctgattc tcagttcggg cactgctttt cctggggaga
     1861 aaacagggag gaagcaatct caaatatggt ggtggcactg aaggagctgt ctattcgggg
     1921 tgactttcga actacagtgg aatacctcat caaactgctg gagacagaaa gctttcagct
     1981 taacagaatc gacactggct ggctggacag actgatcgca gagaaagtgc aggcagagcg
     2041 acctgacacc atgttgggag ttgtgtgtgg ggctctccat gtagcagatg tgagcctgag
     2101 gaacagcatc tctaacttcc ttcactcctt agagaggggt caagtccttc ctgctcacac
     2161 acttctgaac acagtagatg ttgaacttat ctatgaagga atcaaatatg tacttaaggt
     2221 gactcggcag tctcccaact cctacgtagt gataatgaat ggctcgtgtg tggaagtgga
     2281 tgtgcatcgg ctgagtgatg gtggcctgct cttgtcttat gacggcagca gttacaccac
     2341 atacatgaag gaagaggtgg acagatatcg aatcacaatt ggcaataaaa cctgtgtgtt
     2401 tgagaaggaa aatgacccat ctgtaatgcg ctcaccgtct gctgggaagt taatccagta
     2461 tattgtggaa gatggcggac atgtgtttgc tggccagtgc tatgctgaga ttgaggtaat
     2521 gaagatggtg atgactttaa cagctgtaga atctggctgc atccattatg tcaaacgacc
     2581 tggagcagca cttgaccctg gctgtgtgat agccaaaatg caactggaca accccagtaa
     2641 agttcaacag gctgagcttc acacgggcag tctaccacag atccagagca cagctctcag
     2701 aggcgagaag ctccatcgag ttttccacta tgtcctggat aacctggtca atgtgatgaa
     2761 tggatactgc cttccagacc ctttcttcag cagcagggta aaagactggg tagaaagatt
     2821 gatgaagact ctgagagacc cctccttgcc tctgctagag ctgcaggata tcatgaccag
     2881 tgtctctggc cggatccccc tcaatgtgga gaagtctatt aagaaggaaa tggctcagta
     2941 tgctagcaac atcacatcag tcctgtgtca gtttcccagc cagcagattg ccaacatcct
     3001 agatagtcat gcagctacac tgaaccggaa atctgagcgg gaagtcttct tcatgaacac
     3061 ccagagcatt gtccagctgg tgcagaggta ccgaagtggc atccgtggcc acatgaaggc
     3121 tgtggtgatg gatctgctgc ggcagtacct gcgagtagag acacagtttc agaacggcca
     3181 ctacgacaaa tgtgtattcg cccttcggga agagaacaaa agcgacatga acaccgtact
     3241 gaactacatc ttctcccacg ctcaggtcac caaaaagaat ctcctggtga caatgcttat
     3301 tgatcagtta tgtggccggg accctacact tactgatgag ctgctaaata tcctcacaga
     3361 gctaacccaa ctcagcaaga ccaccaacgc taaagtggcg ctgcgcgctc gtcaggttct
     3421 tattgcttcc catttgccat catatgagct tcgccataac caagtagagt ctatcttcct
     3481 atcagccatt gacatgtatg gacaccagtt ttgcattgag aacctgcaga aactcatcct
     3541 ctcggaaaca tctattttcg atgtcctccc aaactttttt taccacagca accaggtggt
     3601 gaggatggca gctctggagg tgtatgttcg aagggcttac attgcctatg aactcaacag
     3661 cgtacaacac cgccagctta aggacaacac ctgtgtggtg gaatttcagt tcatgctgcc
     3721 cacatcccat ccaaacagag ggaacatccc cacgctaaac agaatgtcct ttgcctccaa
     3781 cctcaaccac tatggcatga ctcatgtagc tagtgtcagc gatgttctgt tggacaacgc
     3841 cttcacgcca ccttgtcagc ggatgggcgg aatggtctct ttccggacct ttgaagattt
     3901 tgtcaggatc tttgatgaaa taatgggctg cttctgtgac tccccacccc aaagccccac
     3961 attcccagag tctggtcata cttcgctcta tgatgaagac aaggtcccca gggatgaacc
     4021 aatacatatt ctgaatgtgg ctatcaagac tgatggcgat attgaggatg acaggcttgc
     4081 agctatgttc agagagttca cccagcagaa taaagctact ttggttgagc atggcatccg
     4141 gcgacttacg ttcctagttg cacaaaagga tttcagaaaa caagtcaact gtgaggtgga
     4201 tcagagattt catagagaat tccccaaatt tttcacattc cgagcaaggg ataagtttga
     4261 ggaggaccgc atttatcgac acctggagcc tgctctggct ttccagttag agttgaaccg
     4321 gatgagaaat tttgacctta ctgccatccc atgtgctaat cacaagatgc acctgtacct
     4381 tggggctgct aaggtggaag taggcacaga agtgactgac tacaggttct ttgttcgtgc
     4441 gatcatcagg cactctgatc tggtcacaaa ggaagcttct ttcgaatatc tacaaaatga
     4501 aggggaacga ctgctcctgg aagctatgga tgaattggaa gttgctttta ataatacaaa
     4561 tgtccgcact gactgtaacc acatcttcct caactttgtg cccacggtca tcatggaccc
     4621 atcaaagatt gaagaatctg tgcggagcat ggtaatgcgc tatggaagtc ggctatggaa
     4681 attgcgggtc ctccaggcag aactgaaaat caacattcgc ctgacaacaa ctggaaaagc
     4741 aattcccatc cgcctcttcc tgacaaacga gtctggctac tacttggaca tcagcctgta
     4801 taaggaagtg actgactcca ggacagcaca gatcatgttt caggcatatg gagacaagca
     4861 gggaccactg catggaatgt taattaatac tccatatgtg accaaagacc ttcttcaatc
     4921 aaagaggttc caggcacagt ccttaggaac aacatatata tatgatatcc cagagatgtt
     4981 tcggcagtca ctcatcaaac tctgggagtc catgtccacc caagcatttc ttccttcgcc
     5041 tcctttgcct tccgacatcc tgacgtatac tgaactggtg ttggatgatc aaggccagct
     5101 ggtccatatg aacagacttc caggaggaaa tgagattggc atggtagcct ggaaaatgag
     5161 ccttaaaagc cctgaatatc cagatggccg agatatcatt gtcatcggca atgacattac
     5221 atatcggatc ggttcctttg ggcctcagga ggatttgctg tttctcagag cttctgaact
     5281 tgccagagca gaaggcatcc cacgcatcta cgtggcagcg aacagtggag ctagaattgg
     5341 acttgcagaa gaaatacgcc atatgttcca tgtggcctgg gtagatcctg aagatcccta
     5401 caagggatac aagtatttat atctgacacc ccaggattat aagagagtca gtgccctcaa
     5461 ttctgtccac tgtgaacatg tggaggatga aggggaatcc aggtacaaga taacagatat
     5521 tatcgggaaa gaagaaggac ttggagcaga gaaccttcgg ggttctggaa tgattgctgg
     5581 ggaatcctca ttggcttacg atgaggtcat caccatcagc ctggttacat gccgggccat
     5641 tggtattggg gcttaccttg tccggctggg acaaagaacc atccaggttg agaattctca
     5701 cttaattctg acaggagcag gtgccctcaa caaagtcctt ggtcgggaag tatacacctc
     5761 caacaaccag cttgggggca tccagattat gcacaacaat ggggttaccc actccactgt
     5821 ttgtgatgac tttgagggag tcttcacagt cttacactgg ctgtcataca tgccgaagag
     5881 cgtacacagt tcagttcctc tcctgaattc caaggatcct atagatagaa tcatcgagtt
     5941 tgttcccaca aaggccccat atgatcctcg gtggatgcta gcaggccgtc ctcacccaac
     6001 ccagaaaggc caatggttga gtgggttttt tgactatgga tctttctcag aaatcatgca
     6061 gccctgggca cagaccgtgg tagttggcag agccaggtta gggggaatac ccgtgggagt
     6121 agttgctgta gaaacccgaa cagtggaact cagtatccca gctgatcctg cgaacctgga
     6181 ttctgaagcc aagataatcc agcaggccgg ccaggtttgg ttcccagact ctgcatttaa
     6241 gacctatcaa gctatcaagg actttaaccg tgaagggcta cctctaatgg tctttgccaa
     6301 ctggagaggt ttctctggtg ggatgaaaga tatgtatgac caagtgctca agtttggcgc
     6361 ttacattgtg gatggcttgc gggaatgttc ccagcctgta atggtttaca tcccgcccca
     6421 ggctgagctt cggggtggtt cttgggttgt gatcgacccc accatcaacc ctcggcacat
     6481 ggagatgtac gctgaccgag aaagcagggg atctgttctg gagccagaag ggacagtaga
     6541 aatcaaattc cgtaaaaagg atctggtgaa aaccatgcgt cgggtagatc cagtttacat
     6601 ccgcttggct gagcgattgg gcaccccaga gctaagcccc actgagcgga aggagctgga
     6661 gagcaagttg aaggagcggg aggagttcct aattcccatt taccatcagg tagctgtgca
     6721 gtttgctgac ttgcacgaca caccaggccg gatgcaggag aagggtgtca ttaacgatat
     6781 cttggattgg aaaacatccc gcaccttctt ctactggagg ctgaggcgcc tcctgctgga
     6841 ggacctggtc aagaagaaaa tccacaatgc caaccctgag ctgactgacg gccagatcca
     6901 ggccatgttg agacgctggt ttgtagaagt tgaaggcaca gtgaaggctt acgtctggga
     6961 caataataag gacctggtgg agtggctgga gaagcaactg acagaggaag atggcgtccg
     7021 ctctgtgata gaggagaaca tcaaatacat cagcagggac tatgtcctga agcagatccg
     7081 cagcttggtc caggccaacc cagaagtcgc catggactcc atcgtccaca tgacccagca
     7141 catctcaccc acccagcgag cagaagttgt aaggatcctc tccactatgg attccccttc
     7201 cacgtaggag gagcttcccg cccacccctg ccctgtctct ggagaagaga gtcgggctgc
     7261 ctctcccatc tgagaccact gtaatgagaa ggcaccggag gcctgagact ggatcagtgg
     7321 catttgcttc ccttgagtgt ttcaggctct gcatgacatc ctgggctata ggatcacaca
     7381 gcccagtcac acatacccga ttcagtattt attagcccag ctatgatgac agtcctcttc
     7441 ccatgcacag gactgagaag gcaatgaaag gtacttgcct gtaccatgag gtcttactag
     7501 actaaagcag gactgccctc cgtcctgcct gccccagcat agggtcgtgt gaacagtgtc
     7561 caagtgtctg cagcccctgc cccatgagcc acagccaaca ggggagggct ggggctgcca
     7621 ggagacgcaa gtccatcgat cactacccca cattgcaacc aagcacatgc caggcactgg
     7681 agagagacag tcccatctaa ccacagcaag ataactgaga aatgtcagag cagaaaatct
     7741 gtcgcaagcc cgtgagaaca cagagataaa ggcaaagcca tgatctaaca ggcaggctca
     7801 aaaccagatc atgtcattgt tcctggtcaa acacactcaa ccacctcagt ggcgtctcag
     7861 tatccctggg gagacggtca ccctgccacc accttatcac tatgtaatca catagtgact
     7921 atacctagga gctaaaggcc tgtgcataag ggccctagcc tctgcgggtg gatggagaca
     7981 ggcaggcagt gcaggagcct gaggtggcta agaggaggct cttttctgtt ggtgataggg
     8041 gaagagtact tcaaaacagg agaagtctct tctggggaca ggttgtcact atggggccat
     8101 gcctattcct ggcagaaggt atggcgggtc acccacctga tgacacctgt gctttcagca
     8161 ccagaaactg gccttcttga tgttaggagg cttccaggga acaagaattc acctgccctt
     8221 aagatacctt acagttcagt ctcggtgctg gtgtttccag acttctgggc cctatgtggc
     8281 cagcaacacg gcttcctcag gggtggcctg aaaagtttaa ctacccattt gtccaagaaa
     8341 gcagctgatg gttcagcatt tgtgttcata aagcaagaat gaagatgatc ataactcgta
     8401 taacatccag tttcaacttt atgactaata catctgtcgc tgaagatcga gaaggaaaaa
     8461 gatacctgcc acagaaacca ttcaagtgag tacttcagtc tgagccttaa cctggattcc
     8521 acgaaaagag ctgacctccc cttcaggagc acctcaagca gatattccag aggaccttct
     8581 caatggtgcc acattgcaag tggacatcca agggactata gatgcaagtt gccccacccc
     8641 cacaagccct ggtggaagga acaggagggc cagagctgga tcaggtgggg agcatcctta
     8701 gtccagaagg aagctccctg gcccctggtt ccctgcttac ctggtaggta aggatgggat
     8761 ttatctctgg cctccacttt tgctacagca cgtccaatcc cacacccccg gtggtatgaa
     8821 agctgctttc ctggagaggt ggagtgggct gggcttgtat aagtcccttt tccctgctgc
     8881 cccatccccg ggaccgggcc gtctcaatac ggagaagtca gagccacggc acatgggcag
     8941 tgtgatggta ccacagccca ttacacatgc agggttactg aggaggaggg tgaatgatgt
     9001 attgacccag actggcttga actgagattg ccatattatc tgtccacttg ttcacaaagc
     9061 agccttcaca cgtgtcagtg agagttcgat ggacacacac gccagcgagc aggggcttca
     9121 gtccaatgca ctcttctcac gttttgttga aataaacctc cacatttgta gaaga
//
