LOCUS       NM_013924               4456 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus activator of basal transcription 1 (Abt1), mRNA.
ACCESSION   NM_013924 XM_990110
VERSION     NM_013924.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4456)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   2  (bases 1 to 4456)
  AUTHORS   Brower,C.S., Veiga,L., Jones,R.H. and Varshavsky,A.
  TITLE     Mouse Dfa is a repressor of TATA-box promoters and interacts with
            the Abt1 activator of basal transcription
  JOURNAL   J Biol Chem 285 (22), 17218-17234 (2010)
   PUBMED   20356838
REFERENCE   3  (bases 1 to 4456)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 4456)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 4456)
  AUTHORS   de Planell-Saguer,M., Schroeder,D.G., Rodicio,M.C., Cox,G.A. and
            Mourelatos,Z.
  TITLE     Biochemical and genetic evidence for a role of IGHMBP2 in the
            translational machinery
  JOURNAL   Hum Mol Genet 18 (12), 2115-2126 (2009)
   PUBMED   19299493
REFERENCE   6  (bases 1 to 4456)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 4456)
  AUTHORS   Oda,T., Kayukawa,K., Hagiwara,H., Yudate,H.T., Masuho,Y.,
            Murakami,Y., Tamura,T.A. and Muramatsu,M.A.
  TITLE     A novel TATA-binding protein-binding protein, ABT1, activates basal
            transcription and has a yeast homolog that is essential for growth
  JOURNAL   Mol Cell Biol 20 (4), 1407-1418 (2000)
   PUBMED   10648625
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL714025.12.
            
            On Apr 28, 2007 this sequence version replaced NM_013924.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029222.1, AK009557.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-281               AL714025.12        27511-27791         c
            282-481             AL714025.12        26408-26607         c
            482-4456            AL714025.12        22286-26260         c
FEATURES             Location/Qualifiers
     source          1..4456
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.65 cM"
     gene            1..4456
                     /gene="Abt1"
                     /note="activator of basal transcription 1"
                     /db_xref="GeneID:30946"
                     /db_xref="MGI:MGI:1353636"
     exon            1..281
                     /gene="Abt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..844
                     /gene="Abt1"
                     /codon_start=1
                     /product="activator of basal transcription 1"
                     /protein_id="NP_038952.1"
                     /db_xref="CCDS:CCDS26338.1"
                     /db_xref="GeneID:30946"
                     /db_xref="MGI:MGI:1353636"
                     /translation="MVKAGELVEQQKAAMEEEANAEAAEDQEEPEDTACSSSSKKKKK
                     VVPGIVYLGHVPPRFRPLHVRNLLSAYGEVGRVFFQAEDHFVKRKKKAAAAAGGKKGA
                     KYSKDYTEGWVEFRDKRVAKRVAASLHNTPMGARKRSPFRYDLWNLKYLHRFTWSHLS
                     EHLAFERQVRRQRLRAEVAQAKRETDFYLRNVEQGQHFLAADGDATRPNSSWTFTQRP
                     TEQEFRARKAARPGGRERARLANVEDQARSNRGLLAKIFGAPLPAESKEKP"
     exon            282..481
                     /gene="Abt1"
                     /inference="alignment:Splign:2.1.0"
     exon            482..4456
                     /gene="Abt1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1253..1258
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abt1"
                     /note="hexamer: AATAAA"
     polyA_site      1274
                     /gene="Abt1"
                     /note="major polyA site"
     regulatory      4250..4255
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abt1"
                     /note="hexamer: AATAAA"
     polyA_site      4273
                     /gene="Abt1"
ORIGIN      
        1 agattcacgg ctgtcgtgct ccccagatct tgccatggtg aaagcgggag agttggtgga
       61 gcagcaaaag gctgcgatgg aggaagaggc gaatgcagag gcggcggagg atcaggagga
      121 gcccgaggac acggcctgca gcagcagcag caagaagaag aagaaggtag ttccggggat
      181 tgtgtacctg ggccacgtcc cgccgcgatt ccggcccctt cacgtacgca acctgctcag
      241 cgcctacggc gaggtgggac gcgttttctt ccaggccgag gaccactttg tgaaacgcaa
      301 gaagaaggca gccgcggccg caggaggaaa gaagggagct aagtacagca aggactatac
      361 cgaaggctgg gtggagttcc gagacaagcg tgtagccaag cgagtggcag ccagtctaca
      421 taacacgccc atgggcgccc gcaagcgcag ccccttccgt tatgacctgt ggaacctcaa
      481 gtatttgcat cgttttactt ggtcccacct cagtgaacac cttgcctttg agcgccaagt
      541 acgaaggcaa cgcctgagag cagaggtcgc ccaagcaaag agagagactg acttctatct
      601 tcgaaacgta gaacagggac aacacttcct tgcagctgat ggggatgcta ctcggccaaa
      661 tagctcctgg acattcaccc agcgtcccac tgagcaggag tttagggccc ggaaagctgc
      721 acggccagga gggcgggaaa gagcacggct ggctaatgtc gaggaccagg cccgatccaa
      781 cagagggctc cttgccaaga tctttggagc ccctctacct gcagagagca aggaaaaacc
      841 gtagtcaata agggactcct ggtgatggaa gaaataccta ccagccctgc gccattctga
      901 tctgcttcct gaagagtgtg accatctagg cagatgtttt ctctattcca cacaccaaga
      961 gtctggtaaa ggccttttgt tggtgtcttt tacctacttt gaacaaatcc tgtaagtgcc
     1021 agcctgagaa ccttactcgt cctatccagg gtgaagacca ctggaggtgc ctgttgtgtt
     1081 ttgtttgatt tctgattgcc tgcctctttc tcagtggaca gctaacagtt tctgactgaa
     1141 agagtggact tgccctccac tagggtagtg gtctgtggtg tttgttcact gtggtggaag
     1201 gctgaattag caggaattgg attagaggtc caatttgagg cttatatttg aaaataaaaa
     1261 ataatttatt tttatatgct ttttagtttt tcattaagta agtttcaact tcttttgaag
     1321 ccatacatgc cgctcagtta ctttagcaca ggcatgattc tcctccaccc atgaatctca
     1381 gttactctat cagatatgat cccaatgctc ctgtgttagt cagggttctg tagagtcaca
     1441 gaacttatgg gtagtctctg tatagtaatg gaatttgttg atggtttacc gactgtagtc
     1501 ttaactccca acagtggtca ggagcacctg tgaatggaag tgcaagggtc tagcagttgc
     1561 tcagtcccac aagacaagca ggtgaaggag ggtcttcctt cttccaatgt cattatgtag
     1621 gtctccttag aagatgtggc ccaggttaaa ggtgtgtgcc gccattcctg gatctgggac
     1681 ttgctttgtc ccacatgacc ttgaactcag agatctcctt tctacggagg aagtagtcca
     1741 atgtagtaaa cctgacacca ggtttctggc tgatcacctc aaagaatctg gggctcagtg
     1801 ttagtttctg ctattggcag atctggcatt cagcggcagc cgtagccagg tcagccttgg
     1861 tgagtggaag tccctgttgt tgagcccgag cataacctcc atctccgtca ccatagccac
     1921 tttgttcatg tgcccattga gcaatgacag ggatggctgg ggaaagaggc tgactgtcca
     1981 cagaacgggt catctaatcc acttgattat tgaactcctc cttggctgaa gtcacctttt
     2041 ggtgagtgtt taaatgggac acaaatatct tcacatcctt tgcccacttg gaaatatcta
     2101 tccacatact tcttccccag atgtctttct caccaatttt caattgttat ctttccaaat
     2161 ccctgaccat ccagccaatc cattggctac aaaccatgag tcagtaaaca gttgtacatc
     2221 tggccatttc ttttgccaaa caaactaata ccacgtgtac tgcccgaagt tttgcccatt
     2281 gtgaagattt tccttcacct gtatctttca gggttgccct ggaaagggat tatactgcag
     2341 ctgtccactt ctgggtggtg cctgcataac gtatagagct atcagaaatc caggtcctag
     2401 tcttcagtca gccaatcata ggaacacccc atgaggctat aggcacatgc ttggcagcag
     2461 atggcattgt aataggagta gaaaccatag gcatttgagc aacttcttca agtaacttgc
     2521 ttgtgccttc aagacctgct ctggcccaat cacatatata ccacttccat ttgataatag
     2581 actgctgctt tgtatgtcct actttacgac tggagggtct gatggcaccc agctcatgat
     2641 ggatagttca agttcaggtt gcttggtaac ttgcaacctg attctggtgt cctattatca
     2701 aatgttcagt ttccactaag gcccaatagc aggccaagag ctgtttttca aagggagaat
     2761 agttgtctgc agatgatggt agagctttgc tttaatatcc caaaggtctt ttctgtgatt
     2821 tccctacagg ggcctgccag aggctccaaa cagcatctct atctgctacc agcacctcaa
     2881 gtgccatcgg gtctgcttga tcatatggtt caggagtaga gcagcctgca cagtagcctg
     2941 gacctgttga agggccttct gtttcaggcc ccacacacgt cacttggtat atgggcctga
     3001 gtaacacacc caagtgagta atatactgtc tccagaatcc aaatagaccc actaaatgtg
     3061 cttttttctt ggtagtggga ggggccaggt gcaataactt atctttcacc ttagaaggaa
     3121 tatctctgca tgtcccacat tactggacct agggactgct ctttataact ttcttatttt
     3181 gtgatagggc ctcactcaag tgagacttag ccttgaactc attctgtaag ttgctcaaat
     3241 tagctttgag ctaactttgg tcaggtaggc tctgaacatg aaatcctgtc tcagcctccc
     3301 aaaaacttgc tgtgaggaga ggcctgtatc aagaggccta gtttcaatat tcttaaataa
     3361 ataaatagaa taataattta ccttcctttt ctttataggg taaatcctta cctggaaaag
     3421 gcatccacaa gctatcacat gccttatctt ttaaaatgtt tcagtattca ttttggtaca
     3481 tgtcttctgt ataaaaactg caaaaagatg tttactaata gatctagggg ttaaaaatac
     3541 tgtcatggtt tgaatatgct tggcccagag agtggcacta tttggaggag tggccttgtt
     3601 ggagtaggtg tgctactgtg gtcatggggt ttaagagcct cactctagct gcctagaagt
     3661 cagtcttcca ctagcagcct tcagatgtag aaccctcagc tctgcctgta tcatgcctgg
     3721 atgctgccag gctcccacct tgatgataat ggactgaacc tctgaacctg taagccagtc
     3781 ccaattagaa gttgtccttt ataagacttg ccttggtcat ggtgtctgtt cacagcagtt
     3841 aaactctaag acagagactg agcctctcaa agatcctacc attccagcca cttttcctgt
     3901 ctccattctc ctccctcagt ccagcccatg tcgtgggtct atcacatgga ctgccttcct
     3961 cagcaccttc tgaaacttcg cttccaacag cctgaacccc tggccccttg ttcccttcct
     4021 cacaagctca agtgcatttc cccttcaaga ttcagtcact tagaatgtca ggctggcttc
     4081 ccccgacttc ccctcctaag gtgagcatcc tgcttctgtg gggctggagc actgttttct
     4141 ctctggggta gctcctcctg ttttacagta attgttgatg tttttaccct ggtgttatca
     4201 gtatgaagat tcaacattat ctttgactct ttagggcttc agtctggtaa ataaatgttc
     4261 actaactctt tgagttgctg tgaggagagg ttttataaaa atcctaaata atacactttc
     4321 tgcactccac tacctgtgat gtttggtttg acaaccagtt tggaaagtgt catctacttg
     4381 tgacagtgat aaggagcgtc aggaaggtct tgatccaaac agtcacaaag gtaataaaag
     4441 tcagatttac atcttc
//
