LOCUS       NM_178688               7152 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus actin-binding LIM protein 1 (Ablim1), transcript
            variant 1, mRNA.
ACCESSION   NM_178688
VERSION     NM_178688.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7152)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7152)
  AUTHORS   Chen,X., Liu,Y., Xu,C., Ba,L., Liu,Z., Li,X., Huang,J., Simpson,E.,
            Gao,H., Cao,D., Sheng,W., Qi,H., Ji,H., Sanderson,M., Cai,C.L.,
            Li,X., Yang,L., Na,J., Yamamura,K., Liu,Y., Huang,G., Shou,W. and
            Sun,N.
  TITLE     QKI is a critical pre-mRNA alternative splicing regulator of
            cardiac myofibrillogenesis and contractile function
  JOURNAL   Nat Commun 12 (1), 89 (2021)
   PUBMED   33397958
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7152)
  AUTHORS   Jin,S.H., Kim,H., Gu,D.R., Park,K.H., Lee,Y.R., Choi,Y. and
            Lee,S.H.
  TITLE     Actin-binding LIM protein 1 regulates receptor activator of
            NF-kappaB ligand-mediated osteoclast differentiation and motility
  JOURNAL   BMB Rep 51 (7), 356-361 (2018)
   PUBMED   29921413
  REMARK    GeneRIF: ABLIM1 is associated with the regulation of preosteoclast
            motility via the PI3K/Akt/Rac1 pathway during RANKL-mediated
            osteoclastogenesis.
REFERENCE   4  (bases 1 to 7152)
  AUTHORS   Zhang,Q., Huang,R., Ye,Y., Guo,X., Lu,J., Zhu,F., Gong,X.,
            Zhang,Q., Yan,J., Luo,L., Zhuang,S., Chen,Y., Zhao,X., Evans,S.M.,
            Jiang,C., Liang,X. and Sun,Y.
  TITLE     Temporal requirements for ISL1 in sympathetic neuron proliferation,
            differentiation, and diversification
  JOURNAL   Cell Death Dis 9 (2), 247 (2018)
   PUBMED   29445148
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7152)
  AUTHORS   Narahara,H., Sakai,E., Yamaguchi,Y., Narahara,S., Iwatake,M.,
            Okamoto,K., Yoshida,N. and Tsukuba,T.
  TITLE     Actin binding LIM 1 (abLIM1) negatively controls osteoclastogenesis
            by regulating cell migration and fusion
  JOURNAL   J Cell Physiol 234 (1), 486-499 (2018)
   PUBMED   29904924
  REMARK    GeneRIF: abLIM1 regulated the localization of tubulin, migration,
            and fusion in osteoclasts. Thus, these results indicate that abLIM1
            negatively controls osteoclast differentiation by regulating cell
            migration and fusion mediated via actin formation.
REFERENCE   6  (bases 1 to 7152)
  AUTHORS   Erkman,L., Yates,P.A., McLaughlin,T., McEvilly,R.J., Whisenhunt,T.,
            O'Connell,S.M., Krones,A.I., Kirby,M.A., Rapaport,D.H.,
            Bermingham,J.R., O'Leary,D.D. and Rosenfeld,M.G.
  TITLE     A POU domain transcription factor-dependent program regulates axon
            pathfinding in the vertebrate visual system
  JOURNAL   Neuron 28 (3), 779-792 (2000)
   PUBMED   11163266
REFERENCE   7  (bases 1 to 7152)
  AUTHORS   Suriyapperuma,S.P., Lozovatsky,L., Ciciotte,S.L., Peters,L.L. and
            Gilligan,D.M.
  TITLE     The mouse adducin gene family: alternative splicing and chromosomal
            localization
  JOURNAL   Mamm Genome 11 (1), 16-23 (2000)
   PUBMED   10602987
REFERENCE   8  (bases 1 to 7152)
  AUTHORS   Kim,H.J., Noben-Trauth,K. and Morell,R.J.
  TITLE     Tectorin-beta (Tectb) maps to mouse chromosome 19
  JOURNAL   Genomics 53 (3), 419-420 (1998)
   PUBMED   9799617
REFERENCE   9  (bases 1 to 7152)
  AUTHORS   Kim,A.C., Peters,L.L., Knoll,J.H., Van Huffel,C., Ciciotte,S.L.,
            Kleyn,P.W. and Chishti,A.H.
  TITLE     Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse
            chromosome 19 and human chromosome 10q25, a region frequently
            deleted in human cancers
  JOURNAL   Genomics 46 (2), 291-293 (1997)
   PUBMED   9417918
REFERENCE   10 (bases 1 to 7152)
  AUTHORS   Roof,D.J., Hayes,A., Adamian,M., Chishti,A.H. and Li,T.
  TITLE     Molecular characterization of abLIM, a novel actin-binding and
            double zinc finger protein
  JOURNAL   J Cell Biol 138 (3), 575-588 (1997)
   PUBMED   9245787
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF404774.1, AC102655.7, AC161518.3 and BE994737.1.
            
            On Apr 18, 2018 this sequence version replaced NM_178688.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1, also known as
            abLIM-l).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF404774.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1222              AF404774.1         1-1222
            1223-1223           AC102655.7         131281-131281
            1224-2723           AF404774.1         1224-2723
            2724-6164           AC161518.3         23795-27235
            6165-6621           BE994737.1         18-474              c
            6622-7152           AC161518.3         27693-28223
FEATURES             Location/Qualifiers
     source          1..7152
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 52.09 cM"
     gene            1..7152
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /note="actin-binding LIM protein 1"
                     /db_xref="GeneID:226251"
                     /db_xref="MGI:MGI:1194500"
     exon            1..319
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..2661
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /note="isoform 1 is encoded by transcript variant 1;
                     actin-binding double zinc finger protein; actin-binding
                     LIM protein family member 1"
                     /codon_start=1
                     /product="actin-binding LIM protein 1 isoform 1"
                     /protein_id="NP_848803.3"
                     /db_xref="CCDS:CCDS38027.1"
                     /db_xref="GeneID:226251"
                     /db_xref="MGI:MGI:1194500"
                     /translation="MPSLLGLKCLGKLCSSEIGKVPSPERASLRNSHRRLLIEDLSVP
                     ETPDPAHRRRGTVIHLVYLYSAGCGPPELRFSSYDPSVAHPQDPHHSSEKPVIHCHKC
                     GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHG
                     CGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPK
                     EASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKD
                     YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHP
                     DCKQSTKTEEKLRPPNIPRSSSDFFYPKSLIRRTGRSPALQLLSPPCLMNSNKNPRQP
                     TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITY
                     EPFYTSGYEDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRH
                     SYTPTTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSDSRPNPPFRHHFLPHVKGN
                     EPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKA
                     SEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRSSGREEDEEELLR
                     RRQLQEEQLMKLNSGLGQLILKEEMEKESRERASLASRYDSPLHSASHAPSSKTSSLP
                     GYGKNGLHRPVSTDFAQYNSYGDISGGVRDYQTLPDGHMPAVRMDRGVSMPNMLEPKI
                     FPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKK
                     KAKLF"
     exon            320..454
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            455..638
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            639..748
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            749..875
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            876..969
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1057
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1116
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1200
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1248
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1326
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1482
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1518
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1648
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1649..1768
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1873
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..1921
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            1922..2062
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..2154
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2155..2257
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2258..2322
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2323..2383
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2384..2391
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2392..2466
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2467..2547
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     exon            2548..7152
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6591..6596
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /note="hexamer: AATAAA"
     polyA_site      6613
                     /gene="Ablim1"
                     /gene_synonym="2210411C18Rik; 2610209L21Rik;
                     4833406P10Rik; 9330196J19Rik; Limab1; mKIAA0059"
                     /note="major polyA site"
ORIGIN      
        1 aggggaactg ctactgggga gccctgcttc ccgggcttct gggtcagatc ttgatgtcat
       61 gtctgctatg ccaagatgcc atccttgctt gggttaaagt gtctggggaa attgtgcagc
      121 tctgagatag gcaaagttcc ctcaccagag agagccagcc tcaggaactc ccacaggaga
      181 ctgcttattg aggacctgag tgtccccgag actcctgacc ctgctcatcg caggcgtggc
      241 acagtcatac atctggtcta tctgtattct gctggctgtg gtccaccaga gctcaggttt
      301 agcagctatg atccatccgt ggcccatcct caggaccctc accactcgtc ggagaaacct
      361 gtcattcact gccataaatg cggggagcca tgcaagggcg aagtgctacg ggtgcagacc
      421 aagcatttcc acatcaaatg cttcacctgc aaagtgtgcg gctgcgacct ggcccagggg
      481 ggcttcttca taaagaacgg ggactatctg tgtaccctgg actaccagag gatgtatggg
      541 acacggtgcc acggctgtgg ggagttcgtg gagggcgagg tggtaactgc cctgggcaag
      601 acctaccacc ccaactgctt cgcctgtaca atctgcaagc gcccatttcc acccggagac
      661 cgagtcacat tcaacgggag agactgtctt tgtcagctct gtgcacagcc gatgtcttcc
      721 agccctaaag aagcctcctg ctccagcaac tgcgccggct gtggaaggga cattaagaac
      781 ggacaggcgc tgctagctct ggacaagcag tggcatttgg gctgcttcaa gtgcaagtcc
      841 tgtgggaagg tcctcaccgg cgagtacatc agcaaggatg gctccccata ctgtgagaaa
      901 gactaccagg ggctctttgg ggtgaagtgt gaagcctgtc accagtttat cacaggaaaa
      961 gtcctggagg caggcgacaa gcattatcat cccagctgcg cacgatgcag cagatgcaat
     1021 cagatgttca cagaagggga agaaatgtat ctgcaaggtt ctaccgtgtg gcatcccgac
     1081 tgtaagcagt ccactaagac agaggagaag ctgcggccac caaacatccc gcgctcttca
     1141 tccgatttct tttaccccaa aagtctgatt cgtcgcacag gacggtcccc agctctgcag
     1201 cttctgtcgc caccctgtct gatgaactcc aacaaaaacc ccaggcagcc caccaggacc
     1261 tcctctgaaa gtatctattc tagaccaggc tccagcatcc ctggttcacc aggccatact
     1321 atctatgcaa aagtagacaa tgaaatcctg gattacaagg atttagcagc catccccaag
     1381 gtcaaggcga tctatgacat cgagcgtcca gatctcatta cctatgagcc tttctacaca
     1441 tcaggctatg aggacaagca ggagagacag agccttggag agtctccaag gactttgtct
     1501 ccaactccat ctgcagaagg ttatcaagat gtccgggatc ggatgatcca caggtccacc
     1561 agccagggct ccatcaactc ccctgtgtat agccggcaca gttacactcc aactacgtct
     1621 cgctcgcccc agcacttcca ccgacctgag ctcttgtctc ctggtgtgca caggtggtct
     1681 cccctgcgca ccagcagctt cagctccacc cacagcgact cccgtcccaa cccccccttc
     1741 cgacaccact tcctccccca tgtcaaaggc aatgagccgt ccagcggccg gaactcccct
     1801 ctcccctacc ggcccgacag ccgccctcta actccaactt acgctcaggc ccctaaacat
     1861 ttccatgttc cagatcaagg gatcaacatt taccgaaaac cacccatcta caaacagcat
     1921 gctgccttgg cagcccagag caaggcttca gaagatatca tcaagttttc caagttccca
     1981 gcagcccagg cgccagatcc caacgagata ccaaagattg agacggacca ctggccgggt
     2041 cccccctcac ttgccgccgt aggaactgac ccgaggcgca gatcaagtgg cagagaggaa
     2101 gatgaagagg agcttttgag acgccggcag cttcaagaag aacagttgat gaagctcaac
     2161 tcaggcctgg ggcagctgat cctgaaggaa gagatggaga aggagagcag agaaagagca
     2221 tcgctggcca gtcgctatga ctctcccctc cactcagctt cccatgctcc atcatctaaa
     2281 acttcatctc tccctggtta tggaaagaat ggccttcacc ggccagtttc cacagacttc
     2341 gctcagtaca acagctacgg agacatcagt ggcggagttc gagactacca gaccctccca
     2401 gatggccaca tgcctgcagt gagaatggac agaggagtat ccatgcccaa catgttggaa
     2461 ccaaagatat ttccatatga gatgctcatg gtgaccaaca gagggcgcaa caaaatcctg
     2521 agagatgtgg atagaacccg gctagagcgc cacttagccc cagaagtatt ttgggagatc
     2581 tttgggatgt ccatacagga atttgacaag ttacctcttt ggagacgcaa cgacatgaag
     2641 aaaaaagcta aactcttcta agtccctcga gtaaacgaca atcaggaaac gaactctcag
     2701 tggcggtggt gcgtagaaca ttatgctaag gcccagaact gatcagagaa tttgttcacc
     2761 accgtctcca ggcagcaacg ccaagggcaa gtctgatctc agcacccacg agccacatcc
     2821 tgggccaagc aacagtaacc cttgccaagc aacgacgggg tagaatttct atgttcccaa
     2881 attcagcagt aacgtccaca tgggaccttt tcacgtgact ctgtggggct tctttctcct
     2941 tttcactttc ccctttaacc catgtctgac ttagtgctgc ctgtgttggt aagagtcagc
     3001 aagtgccctt aggaagccac acggagggga tgctgggagt cctgacatat gaatctattt
     3061 attatgtagt actgtggcag agaaggaatc caggggcctg cactgatcgg gtagcagcta
     3121 ctttgcctgt ccttggccgt ctccctcagc tctgcctggg ctccgaggga gatggaagtc
     3181 cgtcagggaa caggtagttc taagtgcgtg gctaaatgat ttggacaagc tcctgtgtgt
     3241 gctgagacct ggctggccag ctgctagagg ggaaaaacaa ttaagacaat ggaaaaggaa
     3301 aaaggaatga aggaacctcc ctccctgaaa gcttttcctg cttctgagac tgtgttcagc
     3361 cctttcccct ataaattgat aggaactgtg tgtccacctt tccaaagaaa ggaaagacaa
     3421 aaagagtttc cagattggcc cagctgctga taggtgattt tttttgccca tgaatcatgt
     3481 atctcttaga gaagaaaatt ctatgcccta ccacatcaca agatctcctc ctcagtgtct
     3541 gtctgtctgt ctgtctgtct gcctggcatc tgatgggtca ggtcaagccc gtgctggttt
     3601 tgactaaggg tagagactaa ggggagactt gtttttctga agtagactgc tttcactcgg
     3661 cctgatggac aagcccgcgt gtgttcacgt ctgtgtgtaa ctcacccaga gcagatctgt
     3721 gagtctcgat gtgctttgta atctctgctt gagtgttgcc catactgggc tgtggctttg
     3781 aaggtcattt gcacaagagc acgtgaccca gagatggaga agtgaggttc agggagggtg
     3841 cttagagacc agcctgttct ttgagctgta gagactcatg ctggattcaa actgagaacc
     3901 ctggaaggaa ggccaggcta gtttagggct cagcgcgtct caccagagcc cttccatact
     3961 ctgtgactct cagtgtgaat tggaatgcaa ttctttccct aaaatgtgtg gaaaaggcca
     4021 catcatgagg actggtgtga gttggggtag ggtccccaga gtctcaggaa agaagctaga
     4081 tcacactgat tctcctgccg tggatatgag ttaaaaccaa gtggtaaagc acttggattc
     4141 acccccaatg accactcagc acaaaatgca gaaattcctt ctgaaggact aaagcgacca
     4201 gctgtctgcc acacctgcag taacacagag caacagattc ccagcccgtg atgagagcct
     4261 gtagctcgtg acacacttct ttgggttact ctgctacatt tctgtaagag agttaagtct
     4321 gagaactagt ctcgcaagtg tatctgttag tacactctgc aagaggactg gactgctggc
     4381 ctaggtatat ggatctcacg cctcttgggg agacagattg caaaaatggg ttccctgcat
     4441 gtctccggct tcttcccatg ttctcattgt ttttctctag ctaccctact catcactggc
     4501 tccctcagca ccaggcctgt ataacgtggt tctcacgtta ccctggcagc atacaggatg
     4561 gggagtctgg tgtattcagt gttcacagtc agcagacatg gtgacctggt gggagacttt
     4621 atttatccag tgtggtgata gcatgaccct ccatgcttct tactggttaa tgctatttct
     4681 cacaatgatg cagattagga aaattgaagt attcaggaaa caggggtggt tgctaaggtt
     4741 ccgtacctgc tctttataaa tttatagtgg ctttatcctg acataggaaa gttcagctgc
     4801 aggggaggag gaggagacag tcttcctctt taagttacag agagccgtaa gctaaaggac
     4861 ctgcctagga ttataatatt tgaagaatga acttttaaat tcttgcaata acgaaaccct
     4921 gcctccttga ctatttgaac tcagttctcc atctaaactg ggaaaaaaaa caaacaaaga
     4981 aacaaacaaa aaaaataaca ttccgtatta gcatagtagt ccaaattgta tcaagcaaaa
     5041 aatgtatggc tagacaacac cagtaagaat cctgctgctc tgggggaggc ggaaggagag
     5101 ctggaaagtc tggagtatcg ctccgttccc tggcagaagg ttccagccag gaggatgtgc
     5161 tgaagatggt ctggtcctaa ctgccagaca caatgtccgt gacattaaag gctccacatg
     5221 attgaccaca gcatgggaga gcggtgttct tcactcgact ccaccctgct ggacacagga
     5281 aaatttcaat tgctaaaaaa aaatcaaagc actcattcac ttggggggag gatcctacgc
     5341 aggggggact tggtgcgtat attaagggct atatttttct agcatttgac ctacttgcga
     5401 cttgatacag attgcatagc ctgaaagagg cttctgtggc cacctgggag tctcagtgtt
     5461 ttcttcaaaa cttctccaag agagtccagg ctctcacatc gtcttcctgt gcgacctatt
     5521 agagagatga aaagcctttg aaaacagcta gctctgcatt ttcatactag tgtagagttt
     5581 gttatgaaat atttttacta tgactccttc aacaactaaa tacgaactgc ctgttctcta
     5641 aacctcaagg agaaaaactg gagttaatgg gtaataaggt gcaaaataaa ggggtaaggg
     5701 gggagttttc tatctgtcct gttctctgtt atctccaagt cctgattctg ttgcctccag
     5761 cccgagcctc ctctcctctt ctctcccgag acacagcctc acccgtcatt tcattctcta
     5821 tccactgtct gtcacctcca gcatggaaag gttcagctgg agacatttct gaaacagact
     5881 actttacttt gaagcaaacg tctttttttt aaagattgct tcaccaatga tgctgtcaga
     5941 tatatctgct ttctcaagtt taaaagaatt caaattaact tcctttgagt ctttgttaaa
     6001 agagaaaata aaaaaatctc aagcaaactt ggagtggcag tccagggcat gtcgcaggag
     6061 caggagtggc tccaagctgt gctctccatg aactctggct ctggggagat ttctagtaac
     6121 tcttcaatct gtactttctg tgcccgcctc ggttttgagt tgcatttttt ttttctgttg
     6181 ttagacaaac cagggctttg tatgcttgaa gttcactgtt ttgtgccccc ctttgaagaa
     6241 ctttctatgc agaaatagat ggtcagggtt tcggatttgc agtgatgtgt cttccggtgg
     6301 caatggacag ggaaggagca cccatgtcca ctggaacggg agaacaagcc ttcggcatct
     6361 acagggttac tgtttgcatt ttctacccac aagcagaagg agacagtgac aatgggcagt
     6421 ggatagccct cactcgtgag tgtttaatgt tgcagcaaac tcaccaagaa ggagacaaat
     6481 ggctgtttcg aatggaagct ttctcagcag acaatgtgtg cacagtaaac ttcagcagag
     6541 tccacttgtt ctcccggaag cttaatgtaa ttgaatggca gttatcacta aataaaattc
     6601 ttttctgagt ctctcccgag agtggcagtc ctttgaatcg cttcccaggg tgaaagatgg
     6661 aaagagatga gcctaaggat accaggttca aaacggttat gaccatacac acaggcattt
     6721 taccttatgg aagaggagac agttgttcat ggaattgatg ggggaggtag agggggtcct
     6781 ctaacaaata tgtctggtgg tgaatgtgaa agctttccat gagatgccaa agaccctaca
     6841 tcgaatttcc ttgaagaatg gttcacggga tttctgtccc tgatgaaaga ctgcccattc
     6901 accttggttc cctccccttg tggctaaacg aaagcaaatg tccggaagtc ttgagaagct
     6961 gtgtcgtgtt ccctgtggaa atgagttgat gtgtgccagt gctgagcacc tggtattgag
     7021 gtacagagga gggctccgcc tgcaggcact gtggccgctg agctgcgtgt tcccagctgc
     7081 ctctgttgcg gacagcccgc tccactctcc accctgtact ccataaataa agctacgtgc
     7141 ttctgccctg ag
//
