LOCUS       NM_009594               5933 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus c-abl oncogene 1, non-receptor tyrosine kinase (Abl1),
            transcript variant 2, mRNA.
ACCESSION   NM_009594
VERSION     NM_009594.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5933)
  AUTHORS   Chandia-Cristi,A., Gutierrez,D.A., Dulcey,A.E., Lara,M., Vargas,L.,
            Lin,Y.H., Jimenez-Munoz,P., Larenas,G., Xu,X., Wang,A., Owens,A.,
            Dextras,C., Chen,Y., Pinto,C., Marin,T., Almarza-Salazar,H.,
            Acevedo,K., Cancino,G.I., Hu,X., Rojas,P., Ferrer,M., Southall,N.,
            Henderson,M.J., Zanlungo,S., Marugan,J.J. and Alvarez,R. A.
  TITLE     Prophylactic treatment with the c-Abl inhibitor, neurotinib,
            diminishes neuronal damage and the convulsive state in
            pilocarpine-induced mice
  JOURNAL   Cell Rep 43 (5), 114144 (2024)
   PUBMED   38656874
REFERENCE   2  (bases 1 to 5933)
  AUTHORS   Vong,K.I., Lee,S., Au,K.S., Crowley,T.B., Capra,V., Martino,J.,
            Haller,M., Araujo,C., Machado,H.R., George,R., Gerding,B.,
            James,K.N., Stanley,V., Jiang,N., Alu,K., Meave,N., Nidhiry,A.S.,
            Jiwani,F., Tang,I., Nisal,A., Jhamb,I., Patel,A., Patel,A.,
            McEvoy-Venneri,J., Barrows,C., Shen,C., Ha,Y.J., Howarth,R.,
            Strain,M., Ashley-Koch,A.E., Azam,M., Mumtaz,S., Bot,G.M.,
            Finnell,R.H., Kibar,Z., Marwan,A.I., Melikishvili,G., Meltzer,H.S.,
            Mutchinick,O.M., Stevenson,D.A., Mroczkowski,H.J., Ostrander,B.,
            Schindewolf,E., Moldenhauer,J., Zackai,E.H., Emanuel,B.S.,
            Garcia-Minaur,S., Nowakowska,B.A., Stevenson,R.E., Zaki,M.S.,
            Northrup,H., McNamara,H.K., Aldinger,K.A., Phelps,I.G., Deng,M.,
            Glass,I.A., Morrow,B., McDonald-McGinn,D.M., Sanna-Cherchi,S.,
            Lamb,D.J. and Gleeson,J.G.
  CONSRTM   Spina Bifida Sequencing Consortiumdouble dagger
  TITLE     Risk of meningomyelocele mediated by the common 22q11.2 deletion
  JOURNAL   Science 384 (6695), 584-590 (2024)
   PUBMED   38696583
REFERENCE   3  (bases 1 to 5933)
  AUTHORS   Ullah,I., Barrie,U., Kernen,R.M., Mamula,E.T., Khuong,F.T.H.,
            Booshehri,L.M., Rhodes,E.L., Bradford,J.M., Datta,A. and
            Wetzel,D.M.
  TITLE     Src- and Abl-family kinases activate spleen tyrosine kinase to
            maximize phagocytosis and Leishmania infection
  JOURNAL   J Cell Sci 136 (14) (2023)
   PUBMED   37357611
REFERENCE   4  (bases 1 to 5933)
  AUTHORS   Leon,R., Gutierrez,D.A., Pinto,C., Morales,C., de la Fuente,C.,
            Riquelme,C., Cortes,B.I., Gonzalez-Martin,A., Chamorro,D.,
            Espinosa,N., Fuentealba,P., Cancino,G.I., Zanlungo,S., Dulcey,A.E.,
            Marugan,J.J. and Alvarez Rojas,A.
  TITLE     c-Abl tyrosine kinase down-regulation as target for memory
            improvement in Alzheimer's disease
  JOURNAL   Front Aging Neurosci 15, 1180987 (2023)
   PUBMED   37358955
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5933)
  AUTHORS   Feng,L., Ding,R., Qu,X., Li,Y., Shen,T., Wang,L., Li,R., Zhang,J.,
            Ru,Y., Bu,X., Wang,Y., Li,M., Song,W., Shen,L. and Zhang,P.
  TITLE     BCR-ABL triggers a glucose-dependent survival program during
            leukemogenesis through the suppression of TXNIP
  JOURNAL   Cell Death Dis 14 (4), 287 (2023)
   PUBMED   37095099
  REMARK    GeneRIF: BCR-ABL triggers a glucose-dependent survival program
            during leukemogenesis through the suppression of TXNIP.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5933)
  AUTHORS   Pilz,A., Moseley,H., Peters,J. and Abbott,C.
  TITLE     Comparative mapping of mouse chromosome 2 and human chromosome 9q:
            the genes for gelsolin and dopamine beta-hydroxylase map to mouse
            chromosome 2
  JOURNAL   Genomics 12 (4), 715-719 (1992)
   PUBMED   1315305
REFERENCE   7  (bases 1 to 5933)
  AUTHORS   Gaskins,H.R., Prochazka,M. and Leiter,E.H.
  TITLE     Chromosomal localization of the murine stress protein gene encoding
            glucose-regulated protein 78 (BiP)
  JOURNAL   Mamm Genome 3 (12), 709-711 (1992)
   PUBMED   1362103
REFERENCE   8  (bases 1 to 5933)
  AUTHORS   Fulchignoni-Lataud,M.C., Szpirer,J., Levan,G. and Weiss,M.C.
  TITLE     Assignment of the rat genes coding for alpha 1-antitrypsin (PI),
            phosphoenolpyruvate carboxykinase (PEPCK), alcohol dehydrogenase
            (ADH), and fructose-1,6-bisphosphatase (FDP)
  JOURNAL   Mamm Genome 3 (1), 42-45 (1992)
   PUBMED   1316195
REFERENCE   9  (bases 1 to 5933)
  AUTHORS   Siracusa,L.D., Jenkins,N.A. and Copeland,N.G.
  TITLE     Identification and applications of repetitive probes for gene
            mapping in the mouse
  JOURNAL   Genetics 127 (1), 169-179 (1991)
   PUBMED   1673105
REFERENCE   10 (bases 1 to 5933)
  AUTHORS   Risser,R., Stockert,E. and Old,L.J.
  TITLE     Abelson antigen: a viral tumor antigen that is also a
            differentiation antigen of BALB/c mice
  JOURNAL   Proc Natl Acad Sci U S A 75 (8), 3918-3922 (1978)
   PUBMED   211509
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ101520.1, CJ128107.1, CJ099623.1, CN663033.1, CK626997.1,
            CF726668.1, CF727248.1, BU053120.1, BM949741.1, CA752052.1 and
            AL929275.8.
            
            On Sep 25, 2013 this sequence version replaced NM_009594.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            coding region, and uses an alternate downstream start codon
            compared to variant 1. The resulting protein (isoform b) has a
            shorter and distinct N-terminus compared to isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090095.1, J02995.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                CJ101520.1         1-44
            45-342              CJ128107.1         40-337
            343-345             CJ101520.1         344-346
            346-525             CJ099623.1         297-476
            526-896             CN663033.1         247-617
            897-1410            CK626997.1         49-562
            1411-2024           CF726668.1         124-737
            2025-2634           CF727248.1         5-614
            2635-2962           BU053120.1         376-703
            2963-3037           BM949741.1         16-90
            3038-3751           CA752052.1         1-714
            3752-5933           AL929275.8         141108-143289
FEATURES             Location/Qualifiers
     source          1..5933
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 21.86 cM"
     gene            1..5933
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /note="c-abl oncogene 1, non-receptor tyrosine kinase"
                     /db_xref="GeneID:11350"
                     /db_xref="MGI:MGI:87859"
     exon            1..177
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..3470
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /EC_number="2.7.10.2"
                     /note="isoform b is encoded by transcript variant 2;
                     proto-oncogene tyrosine-protein kinase ABL1; p150;
                     proto-oncogene c-Abl; abelson murine leukemia viral
                     oncogene homolog 1; Abelson murine leukemia oncogene;
                     Abelson tyrosine-protein kinase 1; c-abl oncogene 1,
                     receptor tyrosine kinase; v-abl Abelson murine leukemia
                     oncogene 1; c-abl protein, type III"
                     /codon_start=1
                     /product="tyrosine-protein kinase ABL1 isoform b"
                     /protein_id="NP_033724.2"
                     /db_xref="CCDS:CCDS15901.1"
                     /db_xref="GeneID:11350"
                     /db_xref="MGI:MGI:87859"
                     /translation="MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSE
                     AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEA
                     QTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ
                     RSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAP
                     KRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED
                     TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE
                     VSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDT
                     YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE
                     LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEK
                     ELGKRGTRGGAGSMLQAPELPTKTRTCRRAAEQKDAPDTPELLHTKGLGESDALDSEP
                     AVSPLLPRKERGPPDGSLNEDERLLPRDRKTNLFSALIKKKKKMAPTPPKRSSSFREM
                     DGQPDRRGASEDDSRELCNGPPALTSDAAEPTKSPKASNGAGVPNGAFREPGNSGFRS
                     PHMWKKSSTLTGSRLAAAEEESGMSSSKRFLRSCSASCMPHGARDTEWRSVTLPRDLP
                     SAGKQFDSSTFGGHKSEKPALPRKRTSESRSEQVAKSTAMPPPRLVKKNEEAAEEGFK
                     DTESSPGSSPPSLTPKLLRRQVTASPSSGLSHKEEATKGSASGMGTPATAEPAPPSNK
                     VGLSKASSEEMRVRRHKHSSESPGRDKGRLAKLKPAPPPPPACTGKAGKPAQSPSQEA
                     GEAGGPTKTKCTSLAMDAVNTDPTKAGPPGEGLRKPVPPSVPKPQSTAKPPGTPTSPV
                     STPSTAPAPSPLAGDQQPSSAAFIPLISTRVSLRKTRQPPERIASGTITKGVVLDSTE
                     ALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLESNLR
                     ELQICPATASSGPAATQDFSKLLSSVKEISDIVRR"
     exon            178..351
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            352..647
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            648..920
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1005
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1183
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1368
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1521
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1611
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1776
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..5933
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3928
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
     regulatory      5087..5092
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5112
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /note="major polyA site"
     regulatory      5777..5782
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
                     /note="hexamer: CATAAA"
     polyA_site      5801
                     /gene="Abl1"
                     /gene_synonym="Abl; c-Abl; E430008G22Rik"
ORIGIN      
        1 ggaggcggga cgcgggcctg ggcgcgggcc tgctgggagc gcggcctggc ggggctgggg
       61 gcccggggtg gtggggcctt cgccgtggcc acgggaccat gttggagatc tgtttgaagt
      121 tggtgggctg caaatccaag aaggggctct cttcgtcctc cagctgctac ctggaagaag
      181 ccctgcagag gccagtggca tctgactttg agccccaggg tctcagcgaa gcagctcgat
      241 ggaactccaa ggaaaacctt cttgctgggc ccagtgaaaa tgaccccaac ctttttgtgg
      301 cactctatga ttttgtggcc agtggagata acactctcag catcactaaa ggtgaaaagc
      361 tccgggtctt gggttataat cacaatgggg aatggtgtga agcccaaacg aaaaatggcc
      421 aaggatgggt cccaagcaac tacatcaccc ccgtcaacag cctggagaaa cattcctggt
      481 atcatggccc tgtatctcgg aatgctgctg agtatctgct gagcagcgga atcaacggca
      541 gcttcttagt gcgggagagt gagagtagcc ctggccagag atccatctcg ctgcggtatg
      601 aagggagggt gtaccactac aggatcaaca ctgcctctga tggcaagctg tacgtgtcct
      661 ccgagagccg cttcaacact ctggctgagt tagttcacca tcactccacg gtggctgatg
      721 gcctcatcac cacactccac tacccagctc ccaagcgcaa caagcccact atctacggtg
      781 tgtcccccaa ctacgacaag tgggaaatgg agcgcaccga catcaccatg aagcacaagt
      841 tgggtggagg ccagtacggg gaggtgtacg agggcgtttg gaagaagtac agcctcactg
      901 tggccgtgaa gaccttgaag gaggacacca tggaggtgga ggagttcctg aaggaagcgg
      961 cggtgatgaa ggagatcaaa caccctaacc tggtgcagct gctaggggtg tgtacccggg
     1021 aaccaccatt ctacataatc actgagttca tgacctatgg gaacctgctg gactacctga
     1081 gggagtgtaa ccggcaggag gtgagcgccg tggtactgct ctacatggcc acacagatct
     1141 catcagccat ggagtacttg gagaagaaga acttcatcca cagagacctt gctgcccgga
     1201 actgcctggt aggggaaaac cacttggtga aggtggctga ttttggcctg agcaggttga
     1261 tgacagggga cacctacacg gcccatgctg gagccaaatt ccccatcaaa tggaccgcac
     1321 ctgagagcct ggcctacaac aagttctcca tcaagtcgga cgtgtgggca tttggagtat
     1381 tgctctggga gattgctacc tatggcatgt caccttaccc gggaattgac ctgtctcagg
     1441 tttatgagct gctggaaaaa gactaccgca tggagcgccc tgaaggctgc ccggagaagg
     1501 tctacgagct catgcgagca tgttggcagt ggaacccctc tgaccggccc tcctttgctg
     1561 aaatccacca agcctttgaa accatgttcc aggaatccag tatctcagat gaggtggaga
     1621 aggagctggg gaaacgaggc acgagaggag gtgctgggag tatgctgcag gccccagagc
     1681 tgcccaccaa gaccagaacc tgcaggagag cagctgagca gaaagatgcg cctgacaccc
     1741 ctgagctgct ccacacgaag ggcctgggag aaagcgatgc actggacagt gagcctgctg
     1801 tatcgccact gcttcctcgg aaagagcgcg ggcccccaga cggcagccta aatgaagatg
     1861 agcgccttct ccccagagac agaaagacca acctgttcag cgctttgatc aagaagaaga
     1921 agaaaatggc gccgacgccc cctaagcgca gcagttcctt ccgagagatg gatggccagc
     1981 cagaccgcag aggggctagt gaggatgaca gcagggaact ctgcaatgga ccaccagctc
     2041 tcacctcaga cgcagcagag cctaccaagt ccccaaaggc cagcaatggg gctggcgtcc
     2101 ctaatggagc cttccgggag ccgggcaact caggcttccg ttctccccac atgtggaaaa
     2161 agtccagcac actgaccggg agccgcctgg ctgctgccga agaggagagc ggcatgagct
     2221 ccagtaagcg cttcctgcgt tcttgttcgg cctcctgcat gccccatggg gcaagggaca
     2281 cagagtggcg gtcggtcacg ctgcctcgag acctgccgtc tgctggcaag cagtttgact
     2341 catccacctt tggagggcac aaaagcgaaa agccagctct gcctcggaaa cgcaccagtg
     2401 agagcaggtc tgagcaggtg gccaaaagca cggcgatgcc ccctccccgg ctggtgaaga
     2461 agaacgagga ggctgctgaa gaaggcttca aagacacaga atccagccct ggctccagcc
     2521 ctcccagctt gactcccaaa ctcctccgca ggcaggtcac tgcctctcct tcctctggcc
     2581 tctctcacaa ggaagaggcc accaagggca gtgcctcagg catggggact ccggccactg
     2641 cagagccagc accccccagc aacaaagtgg gcctcagcaa ggcctcctct gaggagatgc
     2701 gcgtaaggag gcacaagcac agctcggagt ccccagggag agacaagggg cgactggcta
     2761 agctcaagcc tgccccgccg cctcctcctg cctgcacagg aaaagcaggc aagcccgcac
     2821 agagccccag ccaagaggcc ggggaggcag gggggcccac aaagacaaaa tgcacgagtc
     2881 tggctatgga tgctgtgaac actgacccca ccaaggccgg cccacctgga gaaggactga
     2941 gaaagcctgt gcccccatct gtgccaaagc cccagtcgac ggctaagcct ccagggactc
     3001 ccaccagccc ggtctccacc ccctccacag caccagctcc ttcacccctg gctggggacc
     3061 agcagccatc ttctgccgcc ttcatccccc tcatatcaac ccgtgtgtct cttaggaaga
     3121 cccgccagcc gccagagcgc attgccagtg gcaccatcac caagggtgtg gttctggaca
     3181 gtactgaggc cctgtgcctt gccatctccc ggaactcaga gcagatggcc agccacagtg
     3241 ctgtactgga ggctggcaag aacctgtaca ctttctgtgt gagctatgtg gactctatcc
     3301 agcagatgag gaacaagttt gccttccgtg aggctatcaa caagctggag agcaacctcc
     3361 gagagctgca gatctgccct gccacagcct ccagtgggcc agctgccacc caagacttca
     3421 gcaagctgct cagctctgtg aaggagatca gcgacattgt ccggaggtag cagcaaccag
     3481 tgtatgtcag caagagatgt tgcagttcac agggctcttg tgcctataaa gatggggaca
     3541 ggggactggg gagctggcgt ctttccccag gagctttaaa gagagacaag cagagcctga
     3601 gggagacctg gatggagcct ggtggagttg gctcttcctc ctgtgttgtg caccagctgc
     3661 cctgcacctt tcctgtccag cccaggcgtc agccacctct cctcactgcc tgtggatggg
     3721 tctcctgctc tgaagactac atctggcctg cctggccacc aggcttctca ctccccggtg
     3781 cctcagaccc agctcccagg tcagcctgga gtgctcttcc ctgtccttgc agaacgacct
     3841 cctctgatgg accttcttgt caccaaggca tgggagcccc tgtgcttact gtacctgcac
     3901 ctttgatgct tacaaactgt ccccgagagc ctgtgctcac tgtgttttca ttggaaggaa
     3961 gctgtcgctt taagggtcat gaggtgctaa agccaggggc ccagatgggt gggcactgga
     4021 aacaggagct gggcagtgtg gtctgtcacc tgctctcagt atcttcagca gtgtgcccgg
     4081 cagatcttgg acagcaagct tgagttttat gggtggcagt cactggctgg ctaggcacat
     4141 agccaggcca aacctaggcc tccaagggct ccccaaaatc tgaatttctg agtagtcttc
     4201 atcccctctc ctgctctaag gtcaggtcca tcctctctgg tccttacctt gatgacaagg
     4261 atccagcctt ctggtgtttt tgagcatttc aaaggtctgc atagaaagga acagccacta
     4321 ggtacaaaca ggcaggaatc tgggctctcc tgagccctga ctgcttctca gaactgctgc
     4381 ttaaccactg agaacagtgc tcagcccaga gctcctgaga gccatgcaca tcacgctggg
     4441 gttgggtgtc ccttgcagac tcagccaggg gggccatatc ttcctcctaa ggcaggcagg
     4501 accagagctg agcacaggca caggtgtggg cgactccttg actaacccag agccgccagc
     4561 ctaggcctcg tgccaggctg acccaaaaca gggcgcatgc ctaggccttg taccaggctg
     4621 gaagacacct ccacactccc tgcttctcca ctgcaggtgt gctgtgctgg ccccaggccc
     4681 acactgatca cctagatgcg ggcctggtag agatgatttc ctctggatgg tcttccatgg
     4741 tcctcgtagc acctcacctc gttacctcca aaggctgctc tgcagcccaa gggaggctgt
     4801 gccacactgc cagcgacctt gaatagccag acaccgccat cccctgacac tgtgctcaca
     4861 aggcccctgc tctgttgctg ccgtgggtgc cactatattt tgtattacac tttgatatta
     4921 cactcttttt taaaatagac ttgcgctctt ataaatgaca tgtaaatagt tcaccactgt
     4981 gccccctctg gcacaccaac agcattcccc ttttttctca gtccagtaca ttttgtttct
     5041 gtatatgact gttttttgaa tccaaatctc tctgtagtat tttttaaata aatgtttaca
     5101 gaactatcga cagactgctt ggtctgtgat tcatctctgc aagccctcat gtcccagccc
     5161 gtgtgtcccg agcatatcgt tgccagctgc ccagctcttg gcagcctcac agcagatggt
     5221 agtgtcctgt gtcgggccgg aagtaggagc ggctaagcac ctgagattct tgctggcgga
     5281 gtgagtccct ccccggcatg cctctgcctt cagccgctca gtgctctctc tctctcatgt
     5341 ggcttcgggt gccagctgtt aggcttcagt ggacagtgaa caaacgcctc ggcaggctcc
     5401 gtggactatg cttcagtcac tggagctcag gcaaggatgc caaggccaca ggctggggtg
     5461 ccctgccact ccaacaactc gccacacaga agctctgcct cccctggctg tcatatgtca
     5521 tgcatgttga agtgggtcgg agttgtccag tgaatctaga cactggccat cctgcaggtc
     5581 ttctgtagcc aatagggtca tccttgagtg gctgtctaac aggaggttcc agggacagcc
     5641 tccacagcta ccacttgtgc ttttgtgtgt gacatgggcc taagagggct cccagtggcc
     5701 tcaagcaagt actgtttgcc tgttttctcg atttcttgta aggccacagg agtgagacct
     5761 gtcaccttgg cccaagcata aaatactcca tgtctccgaa ataaggtcct gatgtgtcat
     5821 tggaaactta tttctgtggc tacctttctt gtcagacgtg gtggtgccca caaaggcagg
     5881 tggcctggcc tacagagcaa gatccggggc agtcagaggg aaaccctggc ttg
//
