LOCUS       NM_001077190            3375 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus abl interactor 1 (Abi1), transcript variant 1, mRNA.
ACCESSION   NM_001077190
VERSION     NM_001077190.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3375)
  AUTHORS   Balekoglu,N., Michaud,J.F., Sauve,R., Ayinde,K.S., Lin,S., Liu,Y.,
            Kramer,D.A., Zhang,K., Steffen,A., Stradal,T., Angers,S., Chen,B.,
            Yam,P.T. and Charron,F.
  TITLE     The WAVE regulatory complex interacts with Boc and is required for
            Shh-mediated axon guidance
  JOURNAL   iScience 27 (12), 111333 (2024)
   PUBMED   39640588
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3375)
  AUTHORS   Verdile,V., Svetoni,F., La Rosa,P., Ferrante,G., Cesari,E.,
            Sette,C. and Paronetto,M.P.
  TITLE     EWS splicing regulation contributes to balancing Foxp1 isoforms
            required for neuronal differentiation
  JOURNAL   Nucleic Acids Res 50 (6), 3362-3378 (2022)
   PUBMED   35253879
REFERENCE   3  (bases 1 to 3375)
  AUTHORS   Aviles,E.C., Krol,A., Henle,S.J., Burroughs-Garcia,J., Deans,M.R.
            and Goodrich,L.V.
  TITLE     Fat3 acts through independent cytoskeletal effectors to coordinate
            asymmetric cell behaviors during polarized circuit assembly
  JOURNAL   Cell Rep 38 (5), 110307 (2022)
   PUBMED   35108541
REFERENCE   4  (bases 1 to 3375)
  AUTHORS   Wang,R., Wang,Y., Liao,G., Chen,B., Panettieri,R.A. Jr., Penn,R.B.
            and Tang,D.D.
  TITLE     Abi1 mediates airway smooth muscle cell proliferation and airway
            remodeling via Jak2/STAT3 signaling
  JOURNAL   iScience 25 (2), 103833 (2022)
   PUBMED   35198891
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3375)
  AUTHORS   Qi,Y., Liu,J., Chao,J., Greer,P.A. and Li,S.
  TITLE     PTEN dephosphorylates Abi1 to promote epithelial morphogenesis
  JOURNAL   J Cell Biol 219 (9) (2020)
   PUBMED   32673396
REFERENCE   6  (bases 1 to 3375)
  AUTHORS   Scita,G., Nordstrom,J., Carbone,R., Tenca,P., Giardina,G.,
            Gutkind,S., Bjarnegard,M., Betsholtz,C. and Di Fiore,P.P.
  TITLE     EPS8 and E3B1 transduce signals from Ras to Rac
  JOURNAL   Nature 401 (6750), 290-293 (1999)
   PUBMED   10499589
REFERENCE   7  (bases 1 to 3375)
  AUTHORS   Xiong,J.W., Leahy,A., Lee,H.H. and Stuhlmann,H.
  TITLE     Vezf1: A Zn finger transcription factor restricted to endothelial
            cells and their precursors
  JOURNAL   Dev Biol 206 (2), 123-141 (1999)
   PUBMED   9986727
REFERENCE   8  (bases 1 to 3375)
  AUTHORS   Zechner,U., Scheel,S., Hemberger,M., Hopp,M., Haaf,T., Fundele,R.,
            Wanker,E.E., Lehrach,H., Wedemeyer,N. and Himmelbauer,H.
  TITLE     Characterization of the mouse Src homology 3 domain gene Sh3d2c on
            Chr 7 demonstrates coexpression with huntingtin in the brain and
            identifies the processed pseudogene Sh3d2c-ps1 on Chr 2
  JOURNAL   Genomics 54 (3), 505-510 (1998)
   PUBMED   9878254
REFERENCE   9  (bases 1 to 3375)
  AUTHORS   Biesova,Z., Piccoli,C. and Wong,W.T.
  TITLE     Isolation and characterization of e3B1, an eps8 binding protein
            that regulates cell growth
  JOURNAL   Oncogene 14 (2), 233-241 (1997)
   PUBMED   9010225
REFERENCE   10 (bases 1 to 3375)
  AUTHORS   Shi,Y., Alin,K. and Goff,S.P.
  TITLE     Abl-interactor-1, a novel SH3 protein binding to the
            carboxy-terminal portion of the Abl protein, suppresses v-abl
            transforming activity
  JOURNAL   Genes Dev 9 (21), 2583-2597 (1995)
   PUBMED   7590237
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845257.2 and CT030013.7.
            
            On Feb 21, 2023 this sequence version replaced NM_001077190.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034476.1, SRR17253011.6168278.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-247               AL845257.2         23338-23584         c
            248-415             CT030013.7         173757-173924       c
            416-592             CT030013.7         150317-150493       c
            593-607             CT030013.7         142448-142462       c
            608-708             CT030013.7         141635-141735       c
            709-849             CT030013.7         139941-140081       c
            850-950             CT030013.7         136252-136352       c
            951-1127            CT030013.7         132669-132845       c
            1128-1214           CT030013.7         129418-129504       c
            1215-1400           CT030013.7         125810-125995       c
            1401-3375           CT030013.7         119307-121281       c
FEATURES             Location/Qualifiers
     source          1..3375
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 15.18 cM"
     gene            1..3375
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="abl interactor 1"
                     /db_xref="GeneID:11308"
                     /db_xref="MGI:MGI:104913"
     exon            1..247
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            248..415
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            416..592
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            593..607
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            608..708
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            709..849
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            850..950
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1127
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1214
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1400
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..3375
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2200..2205
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="hexamer: AATACA"
     polyA_site      2218
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="major polyA site"
     regulatory      2881..2886
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="hexamer: ATTAAA"
     polyA_site      2905
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="major polyA site"
     regulatory      3059..3064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="hexamer: AATAAA"
     polyA_site      3084
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="major polyA site"
     regulatory      3166..3171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="hexamer: AACAAA"
     polyA_site      3192
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
     regulatory      3346..3351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
                     /note="hexamer: AATAAA"
     polyA_site      3375
                     /gene="Abi1"
                     /gene_synonym="abi-1; E3B1; NAP1; Ssh3bp1"
ORIGIN      
        1 gcagtcccac aatacccggc ggagggaggg tgggtggttg gcgtctggtc tgtgcggagc
       61 tcgggtcccc ggcggactca gcttcctctg tctctttaat gcgagaggaa gcgatgcgga
      121 ggggtggaaa atggcagagc tgcagatgtt actagaggag gagatcccgt ctggcaagag
      181 ggcgctgata gagagttacc agaacctgac ccgggtggcg gactactgtg aaaacaacta
      241 tatacaggct acagacaaga gaaaagctct agaagagacc aaagcatata caactcaatc
      301 tctagctagt gttgcttatc aaataaatgc attggccaac aatgtgctcc agctgctgga
      361 tatccaagca tctcagctgc ggaggatgga gtcatccatc aatcacatct cacagactgt
      421 ggatattcat aaagaaaaag tggctcgaag agagattggt attttgacaa caaataagaa
      481 tacatcaaga actcacaaaa taatcgcacc cgcaaatatg gagcgtcctg tcaggtatat
      541 tcggaaacct atcgactata cagttctgga tgatgtgggc catggagtta agtggctaaa
      601 agccaagcac ggaaataacc agcctgcaag aactggcaca ttgtcgagaa caaaccctcc
      661 cacgcagaaa ccaccaagcc ctcccgtgtc gggccgaggg actttgggac ggaatacccc
      721 ttacaaaacc ctagagcctg ttaagcctcc aacagttccc aatgactaca tgactagtcc
      781 tgcgaggctt ggaagccagc atagtccagg caggacagct tctttaaatc agagaccaag
      841 gacgcatagt ggaagtagtg gaggaagcgg aagccgagag aacagtggga gcagcagcat
      901 tggcattcct attgctgtgc ctacgccctc accgcccact gcgggcccag cagcccctgg
      961 cgcagctcct ggttcccagt atggcacaat gaccaggcag atttctcgac acaactctac
     1021 cacttcttcg acatcttctg gtggatatag acgaactcct tctgtggccg cccaattctc
     1081 tgctcagcct catgttaatg gaggtccact ttattctcaa aattcaattt ctgttgcccc
     1141 tcctcctccc cccatgcctc agttgactcc acagatccct ctcacaggct tcgtggccag
     1201 ggtgcaggaa aacattgctg atagcccaac tccaccacca ccccctccac cagatgacat
     1261 tcccatgttt gatgactctc cgcctcctcc gccacctcct cctgtggact atgaagatga
     1321 ggaagctgca gtagttcagt atagtgaccc atatgcagat ggggaccctg catgggctcc
     1381 caagaactat attgagaaag ttgttgcaat atatgattat acaaaagaca aggatgatga
     1441 gctgtccttt aaagagggtg caatcatcta tgttataaag aagaatgatg atggctggtt
     1501 tgaaggagtt tgcaatcgag tgactggact cttccctggg aactatgttg aatcaatcat
     1561 gcactatact gattagtttt tcttttttct tttcatgtag gttattactc cgtcatactg
     1621 tgggattata tggttaacag aattgtttta atgtttaaaa tgtgcccata ttttcaagga
     1681 catgttttat tggtatattt ggatgtctac ctgtaagcat aaattttgga ggcagttcaa
     1741 acattgctga gcagcagttt atatgcctat aattgattat gcatatgtac tcacaccttg
     1801 ctaagtttat gaccagccta aaacttctgg ggattgggta ttatgtttaa caaatcatgg
     1861 ttcagaatgc accattacat gtttcagtgc agcatggtca ctaacattgt gtcagactaa
     1921 taggaaaaaa cagaaaacgt caatgctggt gctggtcata cttttggttt caattctcat
     1981 ttttaaaaaa atactgtgtt taaagcatgc ataaattttt atgtattgaa atatacttaa
     2041 caattcaaga tgcttccaat ttgtgtaacg attatctgga gtactcatac ttgagtctcc
     2101 taagctctcc atgtgaaatg aaagactatc tgtaatgttg taatttgtat ctaagttttt
     2161 taatgagtga aatttgcatt ataaattttt ccattcataa atacataagt gaaccaaagg
     2221 attttggcct ctcctttact ggtttgcttt aattatgtat gctagtgcat atgcatgcac
     2281 accctcccac ccctttaaga aagatttatt gcagaattat ggttctattt tctcaatgca
     2341 tcagttttga aaatattttt agcttaatct taatgtgtcc aaacagtcaa tgtgacagaa
     2401 ttttgcagat tttggagcta gactgtgtca gagtaagcac atgatattct gggggcaaca
     2461 tctgaaggag gagtgccaca ccggtccttt ggattttaat gaaactgaat ttacattgac
     2521 tcagtgaaag gaaaatcctt tacatattgt aaagatggat gcagttcatt tgtggatagg
     2581 catatttaat ccattccctg gcactagaaa cataaaattt tacaataatt ttgaaagaaa
     2641 ctaggccatg tattaatctg taaacaggta ataagcaggt ttgtattgta actttgatgc
     2701 aacacatgca ctttgtgtgt ctccttgatt caagggaggg tgtgagggat acttctcttg
     2761 tatataagac tgtactgctt aggatattaa agtagatcac acaagtgtgg gtttctatgt
     2821 actgagggtt gcagatttat gacagcatag tgatgagagc agtgcaaaat atttctgaaa
     2881 attaaagacc attgttccta ccaaatcaat gattccatat atattttaac ctttgttatt
     2941 tttgaagtac tatgtcatta gcaatcagat agctttttat tatgcatttc ctttttgaag
     3001 caaaatgttt tcttcatttg taaataacct gttgtctaaa ttttatctag tcttttataa
     3061 taaactatgc tcctatatga aaaatttgga tattgttaaa gtataactaa tgtggattta
     3121 aatagtacag acttcaaaat tctctgacct ttaatcctat ggtgaaacaa agacaaacca
     3181 cttgaatttt aacgttgatt atttatttgt gtaatggctt tacatgtggg cattaacagt
     3241 gtaaacaata ccacatataa ccatcaggat acctcgatta gaatttatag gactataatg
     3301 acactggttt aattacattt aaaaagtttt ccgaaaaact ttgccaataa aaattgccca
     3361 tcaataaggt tgaaa
//
