LOCUS       NM_022419               1985 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Mus musculus abhydrolase domain containing 8 (Abhd8), mRNA.
ACCESSION   NM_022419
VERSION     NM_022419.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1985)
  AUTHORS   Albrecht,N.E., Alevy,J., Jiang,D., Burger,C.A., Liu,B.I., Li,F.,
            Wang,J., Kim,S.Y., Hsu,C.W., Kalaga,S., Udensi,U., Asomugha,C.,
            Bohat,R., Gaspero,A., Justice,M.J., Westenskow,P.D., Yamamoto,S.,
            Seavitt,J.R., Beaudet,A.L., Dickinson,M.E. and Samuel,M.A.
  TITLE     Rapid and Integrative Discovery of Retina Regulatory Molecules
  JOURNAL   Cell Rep 24 (9), 2506-2519 (2018)
   PUBMED   30157441
REFERENCE   3  (bases 1 to 1985)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 1985)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1985)
  AUTHORS   Inoue,S., Sano,H. and Ohta,M.
  TITLE     Growth suppression of Escherichia coli by induction of expression
            of mammalian genes with transmembrane or ATPase domains
  JOURNAL   Biochem Biophys Res Commun 268 (2), 553-561 (2000)
   PUBMED   10679242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127416.7 and AK003090.1.
            
            On Sep 3, 2009 this sequence version replaced NM_022419.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003090.1, AK155503.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                AC127416.7         126240-126251       c
            13-432              AK003090.1         1-420
            433-433             AC127416.7         124326-124326       c
            434-1588            AK003090.1         422-1576
            1589-1985           AC127416.7         119294-119690       c
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.43 cM"
     gene            1..1985
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /note="abhydrolase domain containing 8"
                     /db_xref="GeneID:64296"
                     /db_xref="MGI:MGI:1918946"
     exon            1..192
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            193..919
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1090
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1307
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1985
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1952..1957
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /note="hexamer: AATAAT"
     regulatory      1958..1963
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /note="hexamer: AATAAT"
     regulatory      1961..1966
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1969
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /note="major polyA site"
     polyA_site      1976
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
     polyA_site      1980
                     /gene="Abhd8"
                     /gene_synonym="0910001L24Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtgggactta cagggccggt ttgctacgcg gctgcgggat gcccctgcgt tgaccgtccg
       61 ggcccgcgcc tgtccgcgct aatgcggcca accccgcacc accatgtaag cggcacctgc
      121 aggtggacgc tggcttctcc gcccgggacc cctgcgtcct gcctcgggcc ccgggcccct
      181 cgatgacctc agaacacacc atgctgactg gggtgacaga tggctttttc tgctgcctgc
      241 tggggactcc ccctaacgcc gtgcggccac tggagagtgt cgagtccagt gacggctaca
      301 cattcgtgga ggtcaagcca ggccgggtgc tgcgggtaaa gcatgcgggg cccgcgccca
      361 tccccacgcc gccaccacca cctcctgaag atgatccagg ggtcaagacg ggccttgtgc
      421 gctgccagcg ccgtatcaca gtgtaccgca acgggaggct ggtggtggag aacctgggcc
      481 gagcgcctcg tgccgacctg caaggccgca gtggctccgg ggacccgcct gctgcactcg
      541 aggttgagct ggctgagccc gcaggaggag acacccgggc caacccaggc agcgggcgac
      601 ggcgccgccc acggcgtccg aagaggacca tccacatcga ctgtgagcag cgcatcacca
      661 gctgcaaggg tgcgcaggct gatgtggtgc tgttcttcat tcacggagtc ggtggctcac
      721 tcgccatctg gaaggagcag ctagacttct ttgtgcgact cggctatgag gtggtggcac
      781 ctgacctggc gggccatgga gccagctctg cgccgcaggt ggcagctgcc tacacctttt
      841 acgcattggc agaggatatg agggccatct tcacacgcta tgccaagaag cgcaatgtgc
      901 tcatcggcca ttcttacggt gtctccttct gtactttcct ggcccacgag tacccagatc
      961 ttgtacacaa agtgatcatg atcaacggtg ggggccccac ggcactggag cccagcctat
     1021 gctccatctt caacatgccc acatgtgtcc tgcactgcct gtcaccttgc ctggcctgga
     1081 gtttcctcaa ggccggcttt gcccgccaag gggccaaaga aaagcagctg ctgaaggagg
     1141 gcaatgcgtt caatgtgtcc tccttcgtgc tgcgggccat gatgagtggc cagtattggc
     1201 ctgaaggcga cgaggtctac cacgcggagc tgacggtacc cgtgctgcta gtgcacggca
     1261 tgcacgacaa atttgtgcca gtggaagagg accaacgcat ggctgagatc ctgctgctgg
     1321 cctttctcaa gctcatcgag gaaggcagcc acatggtgat gctggagtgt cctgaaacgg
     1381 tcaacacgct gttacacgag ttcctgctgt gggagccaga acccgaggct gagccaaagc
     1441 tcgagccaaa gcccaagcca cagctgctgc agccagagcc ggctccaggg gaggagaagt
     1501 gaccagcggc gcagggactc ctggatcttg agtagtagag gctcttagac tgggcgtggg
     1561 ctggctgggc ggggcctcat gccgatgggc ggggcctggg catgccccag agcgaaccag
     1621 gcacagtcag tgttggagac tcagtgccca gggcagctat ggtgcccttt ccacgcgcga
     1681 ccgaagggtg tgaccttgta cagagccccc tccctgcctc cccgagtccc tgaagctgca
     1741 gcgcgcgggc tgccatccca ctcggtcttc ccctccgctg tgctccattc cgcactggga
     1801 agccctaagg agaatcctgg ggaagggctc ctatcctgtc ctgggagacc ctaccgcgcc
     1861 atccccattg cttgggactg ggagctaggc acccaaggag ggaggggtcg gagccacaaa
     1921 tccccgcata tggcaacttg taagtcaata aaataataat aataaaaaag acaatccaaa
     1981 ctggc
//
