LOCUS       NM_026622               4341 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus abhydrolase domain containing 18 (Abhd18), transcript
            variant 1, mRNA.
ACCESSION   NM_026622
VERSION     NM_026622.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4341)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160757.3.
            
            On Dec 13, 2019 this sequence version replaced NM_026622.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219379.41579.1, AK169375.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-185               AC160757.3         50201-50385         c
            186-293             AC160757.3         39651-39758         c
            294-378             AC160757.3         38688-38772         c
            379-479             AC160757.3         34041-34141         c
            480-558             AC160757.3         27880-27958         c
            559-643             AC160757.3         27688-27772         c
            644-671             AC160757.3         25239-25266         c
            672-810             AC160757.3         21093-21231         c
            811-900             AC160757.3         14418-14507         c
            901-1002            AC160757.3         13662-13763         c
            1003-1381           AC160757.3         10742-11120         c
            1382-1544           AC160757.3         9615-9777           c
            1545-4341           AC160757.3         6506-9302           c
FEATURES             Location/Qualifiers
     source          1..4341
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 19.58 cM"
     gene            1..4341
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /note="abhydrolase domain containing 18"
                     /db_xref="GeneID:269423"
                     /db_xref="MGI:MGI:1915468"
     exon            1..185
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            186..293
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..1596
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; abhydrolase domain-containing protein 18;
                     alpha/beta hydrolase domain-containing protein 18; protein
                     ABHD18"
                     /codon_start=1
                     /product="protein ABHD18 isoform a precursor"
                     /protein_id="NP_080898.2"
                     /db_xref="CCDS:CCDS38422.2"
                     /db_xref="GeneID:269423"
                     /db_xref="MGI:MGI:1915468"
                     /translation="MGVSKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRER
                     CQNLVSSDYPVHIDKVEEQSDCKILDGHFVSPMAHYVPGIMPIESVVARFQFIVPKEW
                     NSRYRPVCIHLAGTGDHHYWRRRTLMARPMIKEARMASLLLENPYYGCRKPKDQVRSS
                     LKNVSDLFVMGGALILESAALLHWLEREGYGPLGMTGISMGGHMASLAVSNWPKPMPL
                     IPCLSWSTASGVFTTGVLSKSINWRELEKQYYTQTVYEEEIIHMLEYCGTDSFKMGHE
                     FMNHLPSNADKLTNLNLVSRTLNLDMTDQVVSPKDAKCHKSGKTSISAPSNGQLLQDT
                     AKMECLNQTLSTNKSWFASYNPQSFHLLNREQRRSNRQKESLIFMKGVMDECTHVANF
                     SVPVDPSLIIVVQAKEDAYIPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFRQA
                     IYDAFERFLHKYAN"
     exon            294..378
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            379..479
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            480..558
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            559..643
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            644..671
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            672..810
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            811..900
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1002
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1381
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1544
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..4341
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2492..2497
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2513
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /note="major polyA site"
     regulatory      4318..4323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4341
                     /gene="Abhd18"
                     /gene_synonym="2310068E01Rik; 3110057O12Rik"
                     /note="major polyA site"
ORIGIN      
        1 acgccccgcc ccgaggacgt cctccctgtc aggctggctg gcagctcgcc tgctgttttg
       61 tacctgagca gattcagctc tctgctgtcc gagctgaggc gaaagtccgg tgccttaagc
      121 gtggagagcg gtggtggcca gaggcttggc gagttcccct tcaggtgtgc ctcggcgagc
      181 ggcctatgct gtttggcact catgggtgta agcaagttag atattctata ccggagactt
      241 cttctcacaa aacttttcat cagaggatgg ggaaggccag aagacctcaa gagactcttt
      301 gaattcagaa agatgattgg aaatcgagaa aggtgccaga acctggtttc aagtgactac
      361 ccggtacaca tcgataaggt tgaagaacag tcagattgta agatcctaga tggacacttt
      421 gtttctccca tggcccacta tgtgcctggt atcatgccaa ttgaatctgt tgttgcaaga
      481 ttccagttta tcgtgcctaa ggaatggaac agcaggtacc gacctgtgtg cattcatctg
      541 gctggaacag gagaccatca ttactggagg cgcagaacac tcatggctcg tcctatgatt
      601 aaggaggcca ggatggcttc attgttgtta gaaaaccctt attatggctg caggaagccc
      661 aaggaccaag taagatccag cttaaaaaat gtgtcagacc tatttgtgat gggaggcgct
      721 cttattcttg agtctgcagc tctcttgcac tggctggaga gggaaggtta tggacctctt
      781 gggatgactg gaatatccat gggaggacat atggcctcct tagcagtgtc caactggccc
      841 aagcccatgc cgttgattcc atgcctgtct tggtccacag catctggggt cttcactacg
      901 ggtgtattga gtaaatcaat taattggcgg gagctcgaaa agcagtatta tacacagaca
      961 gtttatgaag aagaaattat tcatatgctt gaatactgtg ggacagattc tttcaaaatg
     1021 ggacacgagt tcatgaatca cttgcctagc aatgcagaca agctgactaa cctgaatctg
     1081 gtttccagaa ctttaaattt agatatgaca gaccaagttg tatccccaaa ggatgccaag
     1141 tgccataagt ctggtaaaac atctatcagt gctccttcaa atggacagct gttgcaagat
     1201 acagctaaga tggaatgctt gaatcaaacg ctctcgacta acaaaagttg gtttgcaagt
     1261 tacaaccctc agtcatttca cctgctcaat agagaacaaa gaagaagcaa tcgtcaaaaa
     1321 gaatctttaa tattcatgaa aggagtcatg gatgaatgta ctcacgtagc aaacttctca
     1381 gttccagttg atccaagcct cattatagtg gtacaagcca aagaggatgc ctatattcca
     1441 cgaacaggag ttcgaagctt gcaagaaatt tggcctggtt gtgaaatccg gtatctagaa
     1501 gggggtcata tcagtgctta tctctttaaa caaggactct tcagacaagc catctacgat
     1561 gcctttgaac gtttccttca taaatatgct aactaattgg attgatgtat tgtataacat
     1621 cctatttcct acaaaaagag tttacccaat gatgatgtga aaaacaagca aacagcacta
     1681 catacttgat tgttgccaaa ttagtctgtg ttgccagtgt tacgggtcag ttacaaactg
     1741 tggatacatt tcagtaatga aaaaactact tgaaaaatac aatcctgaag tatttgtaac
     1801 tctttaaaaa atctcatata ccttatacaa catctgttgt tactatttat gaaaacattt
     1861 taattgtgaa taatttattg attcagaata aatagaaact attggttttt taatagaatt
     1921 gttgaaacta aaattgtaac atcacatgta ctgtatattg ttctatggca gttttgctat
     1981 taacttgatt ttaaaaactc gtgtctatcc tttttgtgtg tgtagtgggt ttataatttg
     2041 gttttcaact ttaggtgatt tattgccata gaaataccta agatataaaa tcagtgttag
     2101 ctttgaatta tgaaaacatc ctgagtgctg agctgcaccc tctgtggtag tgcacttgta
     2161 gtcccagcac ttgggaagtg gagacaggag tgtcaggagt ccagccattc tgtttttcat
     2221 agcaaaattt gaggccagcc tgagctgtat gagaccctgt ctcaaacaat tgcctggcat
     2281 ggtagctcat gactttaatc ttagcgggta ggagacagag ccaagcagat ctcttgaagt
     2341 gccaaggctg ggaccatgct tgcccagcct acctagactc tgaggccagt ccccagcact
     2401 gccaaatgaa aagaaaagct ggaggtattt gggaaatggg ggttatacat gttttctcta
     2461 cttaagagag ttttatgtcg aaaatggaaa taataaaaga acattgtact agatggtggg
     2521 ttctgtcaga catttcttat acacctgttc ttcagttgct tacagactga gttaacaact
     2581 ttgacctttt aatttcagaa tttaaaagct acatattaaa ttaaaccatt gtacagaaaa
     2641 acacgaggtt ttacacactg ctagcttttt aaatggaaat tatatggata gatatttggt
     2701 gctaatgtta aactgctctg agctaaaatg tttaaaaggc aaatgtgttt actttgaaat
     2761 ctgtattgcc cttaaattta aattaggtct tgcaggtcta gtgaggatat gtggattgta
     2821 acataccttc tgcagctttt taaaaagatg ctatcgcact ccaatgtctt tgccactaaa
     2881 atttctacca gctatttaaa catctttact gtgaaatcat tgatagcaaa gaagtagctt
     2941 cttggacatt actttttaag gtttattaat tttatgtata taagtacact gtcactgtca
     3001 tcagacatat cggaagaggg catcagatcc tattacagat ggttgtgatc taccatgtgg
     3061 gtgctgggaa ctgaactcag gacctctgga agagcagtca gtgctcttga ccactgagct
     3121 atctctcagc cccttggaca ctattttcaa gtaacattac agtagagctg ttagagctac
     3181 agcaattttg tactttcagg cttgaataca aatacaagaa aacctggtca tggttgtggt
     3241 ggtgcatgcc tttaattcca gcaaagtcag gtactctctg agttggaggc cagcctctgg
     3301 gctacacaga gaaaccctgt cttgaaaaca aaacaaaacc acaaaacaaa caaaaaagca
     3361 aaagaactgg gtgtaggacc atgagtggtg gcaccctctt cctcctgcac tgggaggcag
     3421 agttcagggt cagccttgtc ttcagaggag ttccaggaca accagggcta cactgggtat
     3481 tactggaggt acatccctga aattcctgca cttgggaggc agagcatcag tcaaccacaa
     3541 ggttcaggcc agaatagtct acataatata ttccagatca actagggcta cctgtcacat
     3601 ataagtttat tttcatcttt taagtggctg tttcaagaca gcattcgcaa aactacctaa
     3661 acttattaat tcagagaaga aaatgccttt actcacattt cttcaaatcc actctgcaaa
     3721 atagtagctt aagtactata aagtctcaaa cccttgggac aaatggctga aatgcttatc
     3781 taacatatca aattgaatct ggccacaagg ttctcccgcc atccctactt ggtttccaca
     3841 ccccgcctcc tatattgaac tctctgaact ttgctgcccc caacatacac acacacacac
     3901 acatacacac acacacacac acacacacac acacacacac acaagttgta tatagtcttt
     3961 gagaaattaa tgtattctca aagaagtcct ctatgccatt ttcctgtcac tttgtggatt
     4021 aggtctatga aatactacag attcattcag agcagagttg caaggagctc accatgggcc
     4081 agtttgaccc aattttattt ggtgtacata agagtgggca ttcttatatg tagctactac
     4141 tctatattta cgactcagcc ctaaagaccc tgaagaagta gttctgtagt tagacttcat
     4201 aatttaccaa tgttgtaagt atatcatttt atcaatgtat tttaatgtgg tgctttctct
     4261 attaaaatat taacaatata acaattttta aaatatttgc caaattttat atttcctaat
     4321 aaaaatctat tttagaaagt a
//
