LOCUS       NM_133722               2252 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus abhydrolase domain containing 17C (Abhd17c), mRNA.
ACCESSION   NM_133722
VERSION     NM_133722.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2252)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2252)
  AUTHORS   Tortosa,E., Adolfs,Y., Fukata,M., Pasterkamp,R.J., Kapitein,L.C.
            and Hoogenraad,C.C.
  TITLE     Dynamic Palmitoylation Targets MAP6 to the Axon to Promote
            Microtubule Stabilization during Neuronal Polarization
  JOURNAL   Neuron 94 (4), 809-825 (2017)
   PUBMED   28521134
REFERENCE   3  (bases 1 to 2252)
  AUTHORS   Yokoi,N., Fukata,Y., Sekiya,A., Murakami,T., Kobayashi,K. and
            Fukata,M.
  TITLE     Identification of PSD-95 Depalmitoylating Enzymes
  JOURNAL   J Neurosci 36 (24), 6431-6444 (2016)
   PUBMED   27307232
REFERENCE   4  (bases 1 to 2252)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101659.12, BM943880.1, AK008906.1 and BQ033953.1.
            
            On Oct 12, 2007 this sequence version replaced NM_133722.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018511.1, SRR1660811.433952.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-519               AC101659.12        124551-125069
            520-1210            BM943880.1         1-691
            1211-2220           AK008906.1         187-1196
            2221-2252           BQ033953.1         1-32                c
FEATURES             Location/Qualifiers
     source          1..2252
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 48.35 cM"
     gene            1..2252
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /note="abhydrolase domain containing 17C"
                     /db_xref="GeneID:70178"
                     /db_xref="MGI:MGI:1917428"
     exon            1..612
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1012
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /EC_number="3.1.2.22"
                     /note="abhydrolase domain-containing protein FAM108C1;
                     family with sequence similarity 108, member C; abhydrolase
                     domain-containing protein 17C; protein ABHD17C"
                     /codon_start=1
                     /product="alpha/beta hydrolase domain-containing protein
                     17C"
                     /protein_id="NP_598483.2"
                     /db_xref="CCDS:CCDS21417.2"
                     /db_xref="GeneID:70178"
                     /db_xref="MGI:MGI:1917428"
                     /translation="MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTV
                     LAPEQRAPAPAATPAPAPAAQPAPAEEGAGPGACSLHLSERADWQYSQRELDAVEVFF
                     SRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYS
                     GYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECA
                     AVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGL
                     AMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS"
     exon            613..792
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /inference="alignment:Splign:2.1.0"
     exon            793..2238
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2216..2221
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /note="hexamer: AATAAA"
     polyA_site      2238
                     /gene="Abhd17c"
                     /gene_synonym="2210412D01Rik; Fam108c; Fam108c1"
                     /note="major polyA site"
ORIGIN      
        1 gcgctccctg cgcttccctc ccgcccgcgg cgggcgccag gccgccccga tgcccgagcc
       61 cggccccagg atgaacggct tctcgctcgg cgagctgtgc tggctcttct gctgccctcc
      121 ttgtccgagc cgcatcgccg ccaagctggc cttcctgccg cccgaaccca cctacacggt
      181 gctggcgccc gagcagcgcg cgcccgctcc cgcggcgacc cccgcgcccg ccccggcggc
      241 gcagcccgct ccggccgagg agggtgcggg ccccggcgcg tgcagcctgc acctgagcga
      301 gcgcgccgac tggcagtact cgcagcgcga actggacgcc gtcgaggtct tcttctcgcg
      361 cacggcccgc gacaaccggc tgggctgcat gttcgtgcgc tgcgcgccct ccagccgcta
      421 cacgctgctc ttctcgcacg gcaacgccgt ggacttgggc cagatgtgta gcttctacat
      481 cggcctgggc tcgcgcatca actgcaacat cttctcttac gactactcgg gctatggtgt
      541 gagctccggc aagccctccg aaaagaatct ctacgctgac atcgacgccg cgtggcaggc
      601 actgcgcacc cggtatggcg tgagtcctga gaacatcatc ctctatggac agagcattgg
      661 cactgtcccc actgtggacc tggcctcgcg gtacgagtgt gcagccgtca tcctccattc
      721 cccactgatg tctggtttgc gtgttgcttt tccggatacc aggaaaacat actgctttga
      781 tgctttcccc agcattgaca agatatctaa agtcacctct cctgtgttgg tcattcacgg
      841 taccgaggat gaggtcatcg atttctccca tggcttggcg atgtatgagc gctgtccccg
      901 tgctgtggag cccctgtggg ttgagggggc tgggcacaat gatatagagc tctatgcaca
      961 gtacctagaa cgactaaaac agttcatatc tcacgagctt cccaactcct gaagacagcg
     1021 gccaacctta cctcattact gtgaagcgag gatccttgtt tgcacacgct ttgactggat
     1081 ttaacagtga tacccaataa ccacagagaa gggcccagcc tttgtgtgtt cttcttaaag
     1141 agctaacaca gtctgtcttt tgtacgtaat ctccaccttc cattaggctg agcagctgga
     1201 ttctcagctg caagaccttg caggagtggg aacgagagct gaccatgagg actggttccc
     1261 agggctgtag actaaagtgt gatcaagtcc gtctcccttg ctgtctgtca cctctgattc
     1321 ccctaccggt gcaggatcac ctctcatcca tgtgccggtg tttgacctgc ggcgctttca
     1381 gccctggtgc catgggtgag attcatatgt gaagctatgg tagtgtaact ggaaactgtc
     1441 gtgagaaatc ctccattaac ttgtattaac acgccagcct ttcccacaca catgcattga
     1501 agaatgattt actggaacta taacagcttc atcaactgtt accatttaaa tacaactgga
     1561 atattcttaa acaacaggaa actggggttt ttttaagtgt aaatttatta ctagccaaga
     1621 gttttaatat tttgattgtc tggtctaata gagcctggcc gactttcctt ctgtaaagtc
     1681 ctccttgtcg gctttcttaa aagtcctgta catatttgca attacattgt gcacagattc
     1741 ttaatggata gatttctttt gtcaggctac aacaacagac tgcagattcc ttgtttgtat
     1801 tgtaaatgat tgaatacatt ttgttaatat gtttttattc ctatgttttg ctattaaaat
     1861 ttttataaca tttccaagac aaaaattcca agtttctgct ttgaagaatt taggtaatta
     1921 aattacccta agctgatctc ttagtttagg agttatttgg gttttgacac tggagttgtg
     1981 ccaggtgaac atcagaaaca agatgcttaa atcattacac taacttgtat tggttgcggg
     2041 attgggtttg gggtcgtttg gtcttatttt agggtttttt ttttttttgt tttttttctt
     2101 cttcaaattt aaaagcctta aatgtactgt aagcctcaga tcgttgtaca actggattgc
     2161 gttggttgcc agtttgtgtg ctgttgcctg gatgcggcac ggtggttggt aatggaataa
     2221 aggacgcatg gatcagaaaa aaaaaaaaaa aa
//
