LOCUS       NM_146096               2475 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus abhydrolase domain containing 17B (Abhd17b), mRNA.
ACCESSION   NM_146096
VERSION     NM_146096.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2475)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2475)
  AUTHORS   Tortosa,E., Adolfs,Y., Fukata,M., Pasterkamp,R.J., Kapitein,L.C.
            and Hoogenraad,C.C.
  TITLE     Dynamic Palmitoylation Targets MAP6 to the Axon to Promote
            Microtubule Stabilization during Neuronal Polarization
  JOURNAL   Neuron 94 (4), 809-825 (2017)
   PUBMED   28521134
REFERENCE   3  (bases 1 to 2475)
  AUTHORS   Yokoi,N., Fukata,Y., Sekiya,A., Murakami,T., Kobayashi,K. and
            Fukata,M.
  TITLE     Identification of PSD-95 Depalmitoylating Enzymes
  JOURNAL   J Neurosci 36 (24), 6431-6444 (2016)
   PUBMED   27307232
REFERENCE   4  (bases 1 to 2475)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   5  (bases 1 to 2475)
  AUTHORS   Puente,X.S., Sanchez,L.M., Overall,C.M. and Lopez-Otin,C.
  TITLE     Human and mouse proteases: a comparative genomic approach
  JOURNAL   Nat Rev Genet 4 (7), 544-558 (2003)
   PUBMED   12838346
  REMARK    Review article
REFERENCE   6  (bases 1 to 2475)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK050879.1, BN000127.1 and BM206433.2.
            
            On Aug 19, 2005 this sequence version replaced NM_146096.2.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR1660815.261408.1, BN000127.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN00849374, SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-332               AK050879.1         126-457
            333-1232            BN000127.1         65-964
            1233-2247           AK050879.1         1236-2250
            2248-2475           BM206433.2         1-228               c
FEATURES             Location/Qualifiers
     source          1..2475
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 15.54 cM"
     gene            1..2475
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /note="abhydrolase domain containing 17B"
                     /db_xref="GeneID:226016"
                     /db_xref="MGI:MGI:1917816"
     exon            1..285
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /inference="alignment:Splign:2.1.0"
     exon            286..755
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..1155
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /EC_number="3.1.2.22"
                     /note="Cgi67 serine protease; abhydrolase
                     domain-containing protein FAM108B1; family with sequence
                     similarity 108, member B; alpha/beta hydrolase
                     domain-containing protein 17B; abhydrolase
                     domain-containing protein 17B; protein ABHD17B"
                     /codon_start=1
                     /product="alpha/beta hydrolase domain-containing protein
                     17B precursor"
                     /protein_id="NP_666208.2"
                     /db_xref="CCDS:CCDS29700.1"
                     /db_xref="GeneID:226016"
                     /db_xref="MGI:MGI:1917816"
                     /translation="MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGS
                     RWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAV
                     DLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADVEAAWLALRTRYGIR
                     PENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNID
                     KISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLER
                     LKQFVSQELVNL"
     exon            756..935
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /inference="alignment:Splign:2.1.0"
     exon            936..2475
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2475
                     /gene="Abhd17b"
                     /gene_synonym="5730446C15Rik; Cgi67; Fam108b; Fam108b1"
                     /experiment="experimental evidence, no additional details
                     recorded"
ORIGIN      
        1 ggtgccaagg aaggcgggct gcggagaagg cagcaccggc cctgcgctgc ggacggcgac
       61 cacggccgcg cgggacctcg ggccggagag ccccggcggc ggccgcccct cgcggcggag
      121 ccgttagtca gcagaacgcg aacgcgcgtg gaggggcccc acgaagcgcg cccgggcacc
      181 gcagctctct ttcgcgtcct cgccgggccg ggccgcgggc gcagagtcgg cgggcggcgc
      241 cccgcggagg acagcgcgtt ggcggccgcg gccgcccagc tgcagaagat gaataatctg
      301 tcatttagtg agctatgttg cctcttctgc tgtccacctt gcccagggaa aattgcttca
      361 aaactagcat tcttgccacc tgatccaact tacacactga tgtgtgatga aagtggaagc
      421 cgctggacct tacacctgtc agagcgagca gactggcagt actcgtcccg agaaaaagat
      481 gctattgagt gtttcatgac aagaaccagt aaaggcaaca gaattgcttg tatgtttgtg
      541 cgttgttcac caaatgctaa gtatacctta ctcttctcac atggaaatgc tgttgatctt
      601 ggtcagatga gcagttttta tataggtctg ggttcccgca ttaattgtaa catattctcc
      661 tatgactact ccggatatgg tgctagttct ggaaagccaa cagagaagaa cctgtatgca
      721 gatgtggaag ctgcctggct ggctcttcgg acaagatacg gcattcgtcc tgaaaatgtg
      781 attatatatg gccagagcat agggacagtg ccatctgtgg acctggctgc tcgctatgag
      841 agtgctgctg ttattcttca ttctcctctc acctcaggaa tgcgagttgc tttccctgat
      901 actaagaaga cctactgttt tgatgcattc ccaaacattg acaaaatctc taagataacc
      961 tctccagtat taataattca cgggactgaa gatgaagtca ttgacttttc ccatggcctc
     1021 gcattgtttg agcgctgcca aagacctgtg gagcccctgt gggttgaagg ggcaggacac
     1081 aatgacgtgg agctttatgg acaatacctt gagaggttaa aacagttcgt gtcacaggaa
     1141 ctggtaaatt tgtaaactac tctgtaaatt tgcagactgg gttttctttt cttgctgaac
     1201 tgcactcctt ggtaaataac ataaaacctg aaggttttgt ttacaaatca tgtaagttgc
     1261 cttcataact gtacaggtaa tgatttgtta acagacttaa tgaaggtttt aattaccata
     1321 acttgaaact ggaaatagca gtatcatgca gtcaggctgt gtaatttata ttttttctgt
     1381 gaattttttt taaacatcaa gatgagtact gtatgaaatt ttaattctat aaaatcaaat
     1441 gctgtaaaag tattgtcaaa tgcttttgca tatcaaaagc aaatttataa atatttttaa
     1501 acatctcaat gtactaaata tcctggtata caaatgtaat attctttcaa aaagctgtat
     1561 atctaaagca attcaagtac tcagaataaa ctgtaaaaaa caaaacggtt tgaaaacatc
     1621 caaattgagt tgatatatac tccactgtac agggatagag gcttaaatgg ttattttatt
     1681 gttaaaaaaa atgcattgac ttttctgtat tctccaatta tagtacattt atcctttaaa
     1741 aaaatgaagt cttaattttt atgccatctg ttaacttagc agctcttcat cctgtcactg
     1801 agaagtcctg atggcgctgg attttaacta gttctgactt atgtttggta ctgtgagaca
     1861 actacttaac attttcattc agttatttaa aggacagtta gggcttcaag aatgattttg
     1921 tatgcaatgt tgttttaaat ttgactaatt attagaactg tagtagtctt ccttatatga
     1981 atacttgaaa ctccgttagt tgatcttcaa gaccacagag agactggctg tttggttcct
     2041 ttccacctct gctgttttta agagtagggc ctgttctttt ggagtagtat ctgagaatgt
     2101 catgggttcc ctcctgaatg caggggataa gaaaacatgc catacatttt atattaacca
     2161 gtatagtaaa aaaaataaaa taaataaata aagctcacac acaaaaacta agttgccttt
     2221 ccttgaatga atcctgcctg aaaaatgaaa gaaaaataaa aaataaacta atggtatata
     2281 gtcttaattt gtaatgaatg agaatcaaaa taatacacac tgtggatatg tttttaaggc
     2341 cttatgtaat tttaattgtt ctgcttgttc tgtggttatg tctaagatta tagtacacga
     2401 tcttcaaagt atatcaaata ttgtgaatcc tttggttcag ctatgtcaaa ttcacagtaa
     2461 aacaacaaat gtacc
//
