LOCUS       NM_145421               1473 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus abhydrolase domain containing 17A (Abhd17a), mRNA.
ACCESSION   NM_145421 XM_994656 XM_994672 XM_994685 XM_994703
VERSION     NM_145421.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1473)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1473)
  AUTHORS   Yan,P., Liu,H., Zhou,T., Sun,P., Wang,Y., Wang,X., Zhang,L.,
            Wang,T., Dong,J., Zhu,J., Lv,L., Li,W., Qi,S., Liang,Y. and Kong,E.
  TITLE     Crosstalk of Synapsin1 palmitoylation and phosphorylation controls
            the dynamicity of synaptic vesicles in neurons
  JOURNAL   Cell Death Dis 13 (9), 786 (2022)
   PUBMED   36097267
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1473)
  AUTHORS   van der Weyden,L., Swiatkowska,A., Iyer,V., Speak,A.O. and
            Adams,D.J.
  TITLE     A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators
            of Pulmonary Metastatic Colonisation
  JOURNAL   G3 (Bethesda) 10 (6), 1869-1877 (2020)
   PUBMED   32245826
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1473)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1473)
  AUTHORS   Puttagunta,R., Gordon,L.A., Meyer,G.E., Kapfhamer,D.,
            Lamerdin,J.E., Kantheti,P., Portman,K.M., Chung,W.K., Jenne,D.E.,
            Olsen,A.S. and Burmeister,M.
  TITLE     Comparative maps of human 19p13.3 and mouse chromosome 10 allow
            identification of sequences at evolutionary breakpoints
  JOURNAL   Genome Res 10 (9), 1369-1380 (2000)
   PUBMED   10984455
REFERENCE   6  (bases 1 to 1473)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC152058.8.
            
            On Feb 3, 2010 this sequence version replaced NM_145421.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC005632.1, SRR7652917.1196703.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849378, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               AC152058.8         168517-168683       c
            168-683             AC152058.8         164857-165372       c
            684-878             AC152058.8         163950-164144       c
            879-1058            AC152058.8         162485-162664       c
            1059-1473           AC152058.8         161991-162405       c
FEATURES             Location/Qualifiers
     source          1..1473
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..1473
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /note="abhydrolase domain containing 17A"
                     /db_xref="GeneID:216169"
                     /db_xref="MGI:MGI:106388"
     exon            1..167
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /inference="alignment:Splign:2.1.0"
     exon            168..683
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..1284
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /EC_number="3.1.2.22"
                     /note="abhydrolase domain-containing protein FAM108A;
                     mFLJ00358 protein; family with sequence similarity 108,
                     member A; abhydrolase domain-containing protein 17A;
                     protein ABHD17A"
                     /codon_start=1
                     /product="alpha/beta hydrolase domain-containing protein
                     17A"
                     /protein_id="NP_663396.1"
                     /db_xref="CCDS:CCDS24027.1"
                     /db_xref="GeneID:216169"
                     /db_xref="MGI:MGI:106388"
                     /translation="MNGLSVSELCCLFCCPPCPGRIAAKLAFLPPDPTYSLVPEPEPG
                     PGGAGAAPSGPLRTSAATPGRWKIHLTERADFQYGQRELDTIEVFVTKSARANRIACM
                     YVRCVPGARYTVLFSHGNAVDLGQMCSFYVGLGTRIGCNIFSYDYSGYGISSGRPSEK
                     NLYADIDAAWQALRTRYGISPDSIILYGQSIGTVPTVDLASRYECAAVVLHSPLTSGM
                     RVAFPDTKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEP
                     LWVEGAGHNDIELYSQYLERLRRFISQELPSQRA"
     exon            684..878
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1058
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1473
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1449..1454
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /note="hexamer: ATTAAA"
     polyA_site      1468
                     /gene="Abhd17a"
                     /gene_synonym="1700013O15Rik; D10Bwg1364e; Fam108a"
                     /note="major polyA site"
ORIGIN      
        1 cttccggggg cggtgttagg tcaagctcac ttccgcccgc ggcggagctg cggtggtggc
       61 ggtgcaggag gctgggtcgg ggtccccggg ggacagacag acggacgcac gggcgggcgg
      121 ccgggagcca tggagtgcgg cccccgggcc ggcgggcgcg ggcggcgggt atcccactgt
      181 atggcatgga gacctgtggc tgtgaggctc ccgggggctc gccttggacc gcgatggggc
      241 ccggctgcgg cctcctaacg ggactgaggt gtgcagcccg cgagctgccg ctgcccgcat
      301 ctcggagcac ccccgcccct cccctggccc ggcgcgggcc cggtgcccgc catgaacggc
      361 ctgtcggtga gcgagctctg ctgcctgttc tgctgcccac cctgcccggg ccgcatcgct
      421 gccaagctcg ccttcctgcc tcccgatccc acctactctc tggtacctga acctgagccg
      481 gggcccggtg gggctggcgc tgccccctcg ggtcccctgc ggacctcagc ggccacaccc
      541 gggcgctgga agatccacct gacggagcgt gctgacttcc agtacggcca gcgcgagctg
      601 gataccatcg aggtcttcgt gaccaagagc gcgcgcgcca accgcatcgc ctgcatgtat
      661 gtgcgctgtg taccgggtgc caggtacacg gttctcttct cgcatggcaa tgcagtggac
      721 ctgggccaga tgtgcagctt ctatgttggc ctgggcacac gcatcggctg caacatcttc
      781 tcttatgact actctggcta tgggatcagc tctggccggc cctcggagaa gaacctctat
      841 gctgacattg atgcagcctg gcaggccctg cgtaccaggt atggcatcag cccagacagt
      901 atcatcctgt atggccagag cattggcact gtgcccacag tggatctggc gtcacgctac
      961 gagtgtgctg cagtggttct gcactcgcct ctcacctcgg gcatgcgggt ggccttccct
     1021 gacaccaaga agacctactg cttcgatgct ttccctaaca tcgagaaggt gtcgaagatc
     1081 acgtcaccgg tgctcatcat ccacggcaca gaggacgagg tgatcgactt ctctcacggg
     1141 ctggcactgt atgagcgctg cccaaaggct gtggagccgc tgtgggtgga gggcgctggg
     1201 cacaatgaca ttgagctgta cagtcaatac ctggagcgcc tacgccgctt catttcccag
     1261 gagctgccca gccaacgcgc ctagccaagc tgcagggacc tcagcagtac atgggcctcc
     1321 tgccgggact gcatgtgacc cggagcccag gaccctgcct ggcaccccag gggccatgag
     1381 ccatgttcag gcgtcagagg tccctcttct ctcctcatgg aagcaaagag aaggaaagag
     1441 ggaaactaat taaaggatta agattttagg gtt
//
